Very happy to share our paper rdcu.be/eUImj out today in @natcellbio.nature.com 🎉🎉🎉 We uncover an unexpected role for endogenous Xist RNA in regulating X-linked genes that escape X-inactivation.

We are excited to share our new preprint: SMARCA2/4-Dependent Chromatin Remodelling Establishes Gene Regulatory Programs in Early Human Embryos and Blastoids. www.biorxiv.org/content/10.64898/2025.12.01.691499v1

Our new preprint is out! 🎉 Happy and proud to have led this project during my PhD, and excited to share this story now as a preprint on bioRxiv. Grateful to my amazing mentors for their guidance and support: @crougeulle.bsky.social , @jfouimette.bsky.social, @pasquelab.bsky.social

🔬 Hot #PhD topic: Single-molecule fluorescence and super-resolution microscopy! Use quantitative nanoscale imaging to map nuclear organization. Apply by Jan 7 to join Johannes Stein’s Lab @jmstein.bsky.social & #IMPRS-BAC #gradschool! 👉 www.molgen.mpg.de/5098010/stei...

📢 Speaker showcase for our 2nd Meeting #Embryo2026 🧬Vincent Pasque @pasquelab.bsky.social from @kuleuvenuniversity.bsky.social will speak about his work on modelling early human embryogenesis with naïve pluripotent stem cells. More information👇 www.molgen.mpg.de/embryo2026

Exciting Research Professorship Position in Stem Cell and Developmental Biology at the University of Leuven. Amazing research ecosystem, great colleagues, high quality of life, tenure track. For those interested in joining us, please see below: www.kuleuven.be/personeel/jo...

🎓 PhD: Defended & Done! ✅ I am thrilled to share that I have successfully defended my PhD in Faculty of medicine, KU Leuven, Belgium! 🌟

In this Review, @eliananehme.bsky.social, @amiteshp.bsky.social, Isabelle Migeotte and @pasquelab.bsky.social give an overview of the embryonic origin and function of extra-embryonic mesoderm in vertebrates from in vivo studies. journals.biologists.com/dev/article/...

How does gene regulation shape brain evolution? Our new preprint dives into this question in the context of mammalian cerebellum development! rb.gy/dbcxjz Led by @ioansarr.bsky.social, @marisepp.bsky.social and @tyamadat.bsky.social, in collaboration with @steinaerts.bsky.social

🎉 Excited to see our review on extraembryonic mesoderm is out in @dev-journal.bsky.social! An often-overlooked but crucial lineage in early embryo development. Also happy that a tree was planted in the Forest of Biologists for this work! 🌱🌳

We have an opening for a Reviews Editor on Development. If you love developmental biology and its academic community, and have an interest in publishing and science communication, this could be the role for you. Full details here: www.biologists.com/wp-content/u...

Registration and abstract submission for YEN 2025 is officially open! We are looking forward to seeing you at the 17th Young Embryologist Network Conference on the 19th May 2025. Attendence is FREE thanks to our amazing sponsors: @biologists.bsky.social @10xgenomics.bsky.social and Azenta.

We are hiring! 3-year BBSRC-funded postdoc position available. TEs, epigenetics, pregnancy: if you love one or more of these keywords, apply through the link below. Please spread the word.

Exciting community effort for robust feeder-free maintenance of human naive pluripotent stem cells with blastoid formation potential. Collaboration with @grazianomartello.bsky.social, @leeboratory.bsky.social @jzylicz.bsky.social @nicolasrivron.bsky.social tinyurl.com/5n6z9rt9

It’s official 🎉 I am excited to share that I will start my lab this spring at the Max Planck Institute for Immunobiology and Epigenetics @mpi-ie.bsky.social in beautiful Freiburg 🤩🗻☀️ I am looking forward to new collaborations and working with the fantastic community in Freiburg & its surroundings!

📢 JOB VACANCY 4-Year Postdoc Position in Protein Design at @bristoluni.bsky.social Develop new peptides and proteins to manipulate, target and probe the mechanisms that underpin intracellular transport by microtubule motors. More: www.bristol.ac.uk/jobs/find-in... Deadline: 6 Feb 2025

NEW: Zhang & co identify the transcription factor GABPA as a regulator of #ZygoticGenomeActivation, epiblast formation and naive #pluripotency establishment. www.nature.com/articles/s41...

🎁 New RNA-Seq tutorial! Learn to run differential expression analysis with DESeq2, and create your own bioinformatics projects using public data and the Expression Atlas 🧬 🖥️ youtu.be/NGbZmlGLG5w

📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...

#NCB2024 In June, Liu, Xie & co profiled putative cis-regulatory elements in mouse #oocytes and pre-implantation #embryos. They further identified the transcription factors TCF3 and TCF12 as key regulators of #folliculogenesis. rdcu.be/d3NiG www.nature.com/articles/s41...

Registrations are open for the first edition of 'Gene regulation, one molecule at a time'! Very excited to bring #SingleMoleculeGenomics and #SingleMoleculeImaging community together @embl.org ! www.embl.org/about/info/c...

I wrote some thoughts about why peer review matters It shapes scientific standards, maintains field coherence & trains new researchers Yes, it needs improvement—but it's the glue that holds scientific progress together briscoelab.org/2024/12/11/i...

Thrilled our plasmid-based CRISPR-Cas13d knockdown approach in chick embryos 🐣 is now In Press @devbiol.bsky.social !! www.sciencedirect.com/science/arti...

Postdoc positions in epigenetics! We have several opportunities to investigate big picture questions on (epi)genome function & mechanisms Based @embl.org near Rome (Italy), we offer full scientific support/facilities, training & funding. Also...☀️🏛️🍕🏖️ See👇or contact me for other options. Pls RS

Here is a brief summary of academic journals and news account. Please help me add more accounts to this list! go.bsky.app/hCfhqn

Please check out this upcoming Gordon Conference (GRC) on Developmental Biology - March 2025 Very diverse and relevant topics! and Gordon Research Seminar (GRS) accompanying it as well ! (speaker list in commentts) www.grc.org/developmenta...

Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment. www.nature.com/articles/s41...

Happy to share our first #bluetorial & our latest #preprint, lead by postdoc @paulchammas.bsky.social. We used CRISPRa to disentangle the close relationship between Dux and MERVL elements in the induction of the 2-cell like state: #TEsky #MERVL www.biorxiv.org/content/10.1... (1/8)

📢 Preprint! How does the environment of a father before conception influence offspring? Even more, how do paternal genetics & ages interact with exposures to affect F1 outcome? We tested this systematically, with intriguing findings & some cautionary tales🧵... www.biorxiv.org/content/10.1...

🚨Abstract deadline- 13th December! 🚨 Join us next March in Liverpool for our Spring Meeting, joined with the BSCB and part of the Biologists@100 @biologists.bsky.social 🎉 Not to be missed! We have annual meetings grants! Next deadline is the 10th of Jan. +Info here : bsdb.org/membership/#...

📣📣📣 Come join us and set up your team in the I2BC Cell Bio Dept! You will find great science, diverse topics and models, spacious labs, supportive environment, and fun colleagues. We are a short (train) ride south of Paris. Please DM me with any questions and help us spread the word 🙏

First post on this platform! Check out our review on" "Early human development and stem cell-based human embryo models" @CellStemCell www.cell.com/cell-stem-ce...

🚨Preprint alert! tinyurl.com/2zkmynsd Did you ever dream of reconstruction #spatial single-cell #enhancer activity in a multicellular organism using massively parallel enhancer-reporter assays? Then Spatial-scERA is the method for you! #spatialOMICs

www.biorxiv.org/content/10.1... Chromosomal Instability in Human Trophoblast Stem Cells and Placentas

We have a very basic starter pack!! If you work on 3D biology and organoids broadly defined and want to be included, leave a comment below go.bsky.app/QeDg2YD

I made a starter pack for single cell and spatial people on BlueSky! 🧬🧪🥳 I’m certain it’s very incomplete, so please just let me know if you’d like to be included 😊 go.bsky.app/U57Mar8

2nd edition of the EMBO Workshop on Dev timing & evolution will take place in Paris. 6-9 May 2025. Save the date!!! coming-soon.embo.org/w25-105

We have 15 PhD positions available as part of the DANIO-ReCODE MSCA DN 🇪🇸🇩🇪🇸🇮🇭🇷🇦🇹🇬🇧 Great opportunity for anyone interested in developmental biology, regeneration, genomics, and computational sciences. For project descriptions and how to apply, check: euraxess.ec.europa.eu/jobs/290548