We were all very sad to learn the death of Pierre Capy. Pierre was a professor at University Paris Saclay, in the 1990s, he started a group working on the evolutionary genomics of transposable elements; this group is still very active today. He was a great teacher, mentor, and colleague.

Pierre Capy était un généticien, un drosophiliste, un acteur majeur dans l'essor de la génétique des éléments transposables en France. Très impliqué dans l'administration de la vie scientifique, il a aussi été directeur du laboratoire LEGS (actuel @EGCE), et un des fondateurs en 2016 de @IDEEV.

Bravo à Gaël Cristofari lauréat du Prix Michel Delalande Ses travaux à l’IRCAN (Université Côte d’Azur, @insermpacacorse.bsky.social , @cnrscotedazur.bsky.social ) sur la « face cachée du génome » et les rétrotransposons ouvrent de nouvelles pistes pour la pharmacologie et la lutte contre le cancer.

We are recruting an assistant engineer for 18 months at LBBE (Lyon, France) in molecular biology of Drosophila. The project is to study the interactions between response to viral infections and control of transposable elements. emploi.cnrs.fr/Offres/CDD/U...

TE x ZFP = Evolution! Writing this with Olga @orpsf.bsky.social & Didier @trono-lab.bsky.social was a major highlight of my 🇨🇭sabbatical. Such a treat! 🍫Hope you enjoy it as much as we enjoy piecing it together.

📖 Les filles sont parfaites pour les sciences, un ouvrage qui met en lumière des chercheuses, ingénieures et techniciennes. 👩‍🔬 48 femmes, 48 parcours, une même passion : la science. Très fière de faire partie de cette belle aventure 💛 📘 En librairie le 15/10 👉 www.editionsmkf.com/femmes-et-sc... 1/2

🔥 Mark the date! 🗓️ Millésime 2026 of the @embo.org Workshop on Pathogen Immunity and Signaling has arrived. Terrific roster of speakers, many spots for talks, spectacular venue in Leiden. Submit your abstract. Join us on 8 – 11 June 2026. meetings.embo.org/event/26-pat...

Join IGMM ! 🧬 Postdoctoral Fellow in Oncogenesis. Apply now 👉 emploi.cnrs.fr/Offres/CDD/U... #Postdoc #OncologyResearch #ScienceJobs #IGMM #CNRS

Happy to share the results of a long-haul post-doc project, now online @science.org, aiming at understanding the rules of transgeneration epigenetic inheritance over TEs in plants and its extent and impact in nature. More below! doi.org/10.1126/scie...

Hi! We are looking for a PhD to work on the cross talk between transposable elements, insects and intracellular bacteria on the bioinformatics side. The PhD would be supervised by @mariefablet.bsky.social and myself along with @nicolasparisot.bsky.social Deadline December 2025! Please share! #tesky

Our new review is out in Trends in Cancer. We had fund writing this :) We discuss the roles of retrotransposons in immune modulation in normal and malignant hematopoiesis. www.cell.com/trends/cance...

New paper from our lab! We found that LINE-1 transposons contribute to early human brain development. Funded by @asapresearch.parkinsonsroadmap.org www.cell.com/cell-genomic...

🦟 Bioinformatics Research Scientist position open in my lab in Nice (FR) to study Aedes mosquito retrotransposons & their interactions with arboviruses collab w/ @salehlabparis.bsky.social & @lambrechtslab.bsky.social Apply: euraxess.ec.europa.eu/jobs/359830 Please boost! #ArboRetro #Bioinformatics

Have you ever wanted to design large and complex ribozymes from scratch? I know I have! We used RNA inverse folding to design synthetic Group II Introns (G2Is) from the bottom up, resulting in highly active #ribozymes that splice in E. coli without proteins! #intron #RNAsky #SynBio 🧬🧵(1/n)

🌊 Tout le mois de juin, dans le cadre de l'Année de la Mer et en marge de l' #UNOC3, retrouvez la très belle exposition du @cnrs.fr "L'océan si fort et si fragile" sur la Promenade de l'Octroi à Villefranche-sur-Mer ! Les experts décryptent ce monde bleu, clé de l’équilibre de notre planète 🌎

Ce 22 mai, le campus Valrose d’Université Côte d’Azur a accueilli plus de 500 élèves issus de 25 classes de collèges et lycées pour la grande restitution de fin d’année des projets scolaires "Science et Société". Une journée placée sous le signe de la curiosité scientifique et de la créativité !

Our paper is now published in its final form: rdcu.be/elV6u @biomedcentral.bsky.social @salehlabparis.bsky.social @merklinglab.bsky.social @pasteur.fr

💥🥳 At long last, our latest paper is out! Gag proteins of endogenous retroviruses are required for zebrafish development www.pnas.org/doi/10.1073/... Led heroically by Sylvia Chang & @jonowells.bsky.social A study which has changed the way I think of #transposons! No less! 🧵 1/n

Interested in the analysis on Transposable elements? 🧬 Have a look at our course with @valentinapeona.bsky.social & @ritarebollo.bsky.social We'll cover everything from TE biology to de novo library construction, quantification, & transcriptomic analysis. www.physalia-courses.org/courses-work...

Fantastic talk by @aktast.bsky.social unraveling how RNA binding proteins tame the TE transcriptome, control their exonization and allow for the peaceful co-existence of TE and host genes. LOVE IT. #TECSHA

Great talk by @emiliebrasset.bsky.social at #TECSHA on the regulation of piRNA production in germline vs somatic compartments of Drosophila ovary. Sophisticated mechanisms have evolved to control different sets of TEs, to the benefit (I think) of both host and TEs.

Hello World! Are you passionate about epigenomics and evolution 🧪🧬🐭🐵 ? Are you looking for a postdoc in a stimulating and inclusive environment ? Look no further... We are seeking creative postdocs for our ERC project EvoEpi @igred.fr ! 👇Details👇 tinyurl.com/PostdocEvoEp... Repost are appreciated

Un scientifique utilise la chimie pour créer des œuvres d'art visuelles époustouflantes. En combinant différents éléments et réactions chimiques, il produit des images fascinantes dans une goutte d'eau 💧!

Our study with Anjana Rao's lab was just published at NSMB 🥳 Shows how OGT prevents TET proteins from activating retrotransposons, particularly those in heterochromatin. Paper has 6-base and ONT sequencing data from OGT iKO mESCs, and also interesting OGT inhibitor data 👀. rdcu.be/efuho

Le mot du mois #Recherche 📚 Les travaux sur les gênes sauteurs offrent de nouvelles perspectives sur l'évolution et la génétique humaine, avec des applications potentielles pour le diagnostic et le traitement des cancers. swll.to/genessauteurs @insermpacacorse.bsky.social

Hi! Here is a PhD opportunity at Montpellier, IGH institute with Séverine Chambeyron to study endogenous retroviruses ! #TEsky #PhD

Our latest paper is out in NAR! 🥳 In collaboration with @saramaciasrna.bsky.social, we show DGCR8 haploinsufficiency disrupts pluripotency in hESC by affecting primate-specific miRNAs and TEs. Our findings highlight a co-evolved miRNA-TE network in primates. Read: academic.oup.com/nar/article-...

🧑‍🔬 Moins de bruit, plus de Science ! Tous les 15 jours, explorez la science autrement avec nos chefs de rubrique @bentonson.bsky.social et Elsa Couderc : découvertes inédites, nouvelles voix, décryptages exclusifs et bien plus encore. ⭐️ Abonnez-vous gratuitement : urlr.me/bnsS7G

#RésultatScientifique🔎 | Vieillissement : un bouclier levé ? @juliencherfils.bsky.social et ses collaborateurs ont découvert comment un glycolipide protège les cellules sénescentes du système immunitaire. En le ciblant, ils parviennent à réduire les effets du vieillissement chez la souris ! 🧪

1/ Transposable elements are often called "jumping genes" because they mobilize within genomes. 🧬 But did you know they can also jump 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 cells? 🤯 Our new study reveals how retrotransposons invade the germline directly from somatic cells. www.biorxiv.org/content/10.1... A short thread 🧵👇

Here, we demonstrate that Starships, a newly discovered group of cargo-mobilizing transposable elements, are active vectors of horizontally transferred DNA among eukaryotic species.

Did you know that two jumping sequences (LINE-1 and Alu) make up nearly 30% of our genomes? Ever wonder how they jump into new genomic sites? We have some exciting discoveries to share new in @science.org on the structural mechanisms of LINE-1 retrotransposition (aka jumping 🧬➡️🧬) 🧪 #ScienceResearch

Université Côte d'Azur s’associe à l'initiative @standupforscifr.bsky.social au sein de l'alliance @udice.bsky.social pour dénoncer les menaces pesant sur la science et la recherche. Mobilisation 7/03 à 13h sur le campus Valrose Le communiqué : swll.to/StandForScie... #StandUpForScience

Place Jussieu at 1:30PM on Friday for the Parisians! @standupforscifr.bsky.social @sufs-paris-rp.bsky.social

📲 Vendredi 28 février 2025 de 14h à 21h, SCIENCE AZUR propose un événement en ligne "DM une scientifique : échange par tchat avec une scientifique" pour inspirer les jeunes à envisager des carrières scientifiques et à promouvoir la place des femmes dans ce domaine. RDV ici : lnkd.in/ej23CBG3

Dear all, registrations are open for the Mobile Genome @EMBO workshop. Many slots for posters, short talks but also long talks for last minute groundbreaking results! Let’s meet again on Nov 4-7, 2025 in Heidelberg. www.embl.org/about/info/c...

Very excited to share our paper on Gene and Transposable Element expression in mammalian preimplantation development, online today! www.cell.com/cell/fulltex... A short thread to highlight some of our findings 🧵

I’m excited to share our latest study led by @giuliapasquesi.bsky.social out today in @cellpress.bsky.social , uncovering a new way transposons have been repurposed for human interferon signaling! Read on for a thread on cryptic splice variants, decoy receptors, and viruses (1/N) 👇🧵 #TESky 🧪

We are recruiting an enthusiastic engineer to identify isoform-splicing regulation in the developing Drosophila embryo with transcriptomics & genetics in our lively team in @igmm-montpel.bsky.social Please reshare! #jobOffer #RNA #hox #Drosophila #Nanopore #splicing emploi.cnrs.fr/Offres/CDD/U...

Tracking transposable element (TE) activity in genomics data can be a pain, but there are solutions! Our lab built TEtranscripts -- which we've updated to work for small RNAs (TEsmall), bulk RNA at the locus level (TElocal), and in single-cell data (TEsingle). Check it out! www.mghlab.org/software

Thrilled to announce that the EMBO workshop «Mobile Genome» will be back in Heidelberg, Nov 4-7th 2025 @EMBLEvents @EMBO. Registration open soon but you can already register interest. Organized with fantastic colleagues @juliusbrennecke @GonzalezLab_BCN @JoePetersLab www.embl.org/about/info/c...

[Inserm] "Génétique : les gènes sauteurs sous contrôle" #recherche #science #génétique

Ce week-end, je ferai partie de la délégation du Café des sciences qui débarquera en force au Play Azur Festival, à Nice ! Au programme : des activités sur le stand du Café, une conférence tirée de la #BattleDuVivant et un créneau de dédicaces. Passez nous voir, ça va être sympa ! #PAF2024

On X, we have over 69,000 followers - but get much less engagement than we get here from our 2,900 followers on #Bluesky. We're a nonprofit news organization dedicated to sharing trustworthy articles, written by academic experts. Please help us out by letting more folks know we're here.

We have two new faculty opportunities at QMUL, part of a £3.2M investment by Barts Charity to develop genomic and epigenomic liquid biopsy analyses for diagnostics and research applications. More details here: qmulepigenetics.com/jobs Please RT abundantly

Postdoc advertised in my lab to study mobile DNA in mammalian genomes. Permanent position with superannuation and tax concessions in addition to advertised salary. Would suit someone straight out of PhD or a more experienced staff scientist. Please repost! www.nature.com/naturecareer...

This is one of the limited edition prints now available in my shop: www.tomgauld.com/shop

I'm so excited to announce that our story on LINE-1 DNA methylation has been published in @CellGenomics 🥳🥳 With @retrogenomics.bsky.social @aurelien-doucet.bsky.social and all other authors. Enjoy the reading! www.cell.com/cell-genomic... See original thread below.

Great initiative by Ilya Kirov to make PhD positions in the transposon / mobile genome field easier to share and find. Here is a link to the google table he created for this: t.co/gW9DYsPQtJ