The Lambrechts Lab
@lambrechtslab.bsky.social
📤 306
📥 146
📝 26
Research unit
@pasteur.fr
investigating arbovirus transmission by mosquitoes.
reposted by
The Lambrechts Lab
Nature Microbiology
15 days ago
OUT NOW! - Engineered Metarhizium fungi produce longifolene to attract and kill mosquitoes 🍄🧲🦟☠️ By Dan Tang, Jun Cao, Raymond Leger, Jianhua Huang, Weiguo Fang & colleagues.
www.nature.com/articles/s41...
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Engineered Metarhizium fungi produce longifolene to attract and kill mosquitoes - Nature Microbiology
Insects colonized with Metarhizium fungi emit longifolene to lure new hosts for infection to disperse spores. A fungal strain was engineered to emit longifolene to attract and eliminate mosquitoes.
https://www.nature.com/articles/s41564-025-02155-9
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reposted by
The Lambrechts Lab
Natural History Museum, London
15 days ago
A long-held myth about a mosquito evolving in the London Underground has been debunked! 🦟 The insect gained notoriety in the Second World War, when it fed on Londoners seeking shelter in the rail tunnels during the Blitz. Discover its true origin story.👇
www.nhm.ac.uk/discover/new...
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Origins of the London Underground mosquito revealed | Natural History Museum
New research reveals that these insects likely evolved in the Mediterranean basin more than 1,000 years ago.
https://www.nhm.ac.uk/discover/news/2025/october/origins-of-the-london-underground-mosquito-revealed.html?utm_source=bls-link-post-20251024-ec&utm_medium=social&utm_campaign=news
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reposted by
The Lambrechts Lab
Wellcome Sanger Institute
15 days ago
The so-called 'London Underground mosquito' linked to West Nile Virus evolved over 1,000 years ago — not 200 years ago in Europe. 🦟 New research reshapes our theories of urban mosquito evolution. 👇
http://bit.ly/4qnJOJi
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Current
#mosquitoes
evolved more recently than previously thought
www.nature.com/articles/d41...
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Current mosquitoes evolved more recently than previously thought
Genetic analysis reveals that most living genera of mosquitoes emerged around 73 million years ago.
https://www.nature.com/articles/d41586-025-03244-9
26 days ago
0
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🚨 New preprint alert! We have developed a targeted amplicon sequencing panel for Aedes aegypti. We believe it is a powerful and cost-effective tool for studying
#mosquito
#population
#genetics
. Curious how it matches up to WGS? Check out our preprint to find out!
www.biorxiv.org/content/10.1...
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A targeted amplicon sequencing panel for cost-effective high-throughput genotyping of Aedes aegypti
The mosquito Aedes aegypti is the primary vector for several medically significant arboviruses, including dengue, Zika, chikungunya, and yellow fever. Studying the genetic diversity of Ae. aegypti is ...
https://www.biorxiv.org/content/10.1101/2025.09.28.679043v1
about 1 month ago
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5
2
reposted by
The Lambrechts Lab
Ben Longdon
about 1 month ago
2 job adverts on a NERC project w myself +
@darrenobbard.bsky.social
on “What determines the virome: ecology and the environment, evolution, or species history?” early 2026 in
@uniexecec.bsky.social
- Postdoc:
jobs.exeter.ac.uk/hrpr_webrecr...
- RA:
jobs.exeter.ac.uk/hrpr_webrecr...
Pls share!
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reposted by
The Lambrechts Lab
Princeton University
about 2 months ago
A study by researchers at Princeton,
@pasteur.fr,
and
@ucsandiego.bsky.social
reveals that Africa’s low rates of Zika virus outbreaks may be due to a surprising factor: the genetic makeup of local mosquito populations.
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Mosquito Genetics May Explain Why Zika Virus Outbreaks Are Rare in Africa – But Climate Change Could Shift the Balance - High Meadows Environmental Institute
A new study reveals that Africa’s low rates of Zika virus outbreaks may be due to a surprising factor: the genetic makeup of local mosquito populations. Research by scientists at the High Meadows Envi...
https://environment.princeton.edu/news/mosquito-genetics-may-explain-why-zika-virus-outbreaks-are-rare-in-africa/?utm_campaign=communications&utm_content=1758575701&utm_medium=social&utm_source=bluesky
0
4
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Huge thanks to
@gonzalezlabbcn.bsky.social
for her invaluable contribution as a member of Alexander Bergman's PhD jury and for the stimulating discussions that ensued. It was a great opportunity to chat about
#transposons
in
#mosquitoes
and
#Drosophila
!
add a skeleton here at some point
about 1 month ago
0
3
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WOW! Systematic testing of 2
#Wolbachia
strains for their ability to block transmission of 60 genetically diverse
#DENV
isolates in
#mosquitoes
shows substantial heterogeneity and suggests potential long-term selection risks in Wolbachia-based control interventions.
add a skeleton here at some point
about 2 months ago
0
3
0
reposted by
The Lambrechts Lab
Erica McAlister
about 2 months ago
www.nhm.ac.uk/discover/new...
Mosquitoes that have been in the collection for nearly a hundred years are helping us in dealing with an even older but also current problem - malaria
@sangerinstitute.bsky.social
@nhm-london.bsky.social
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Genetic study of malaria-carrying mosquitoes tracks evolution of insecticide resistance | Natural History Museum
It crucially also reveals promising genetic targets for potential control.
https://www.nhm.ac.uk/discover/news/2025/september/genetic-study-of-malaria-carrying-mosquitoes-evolution-of-insecticide-resistance.html
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How the yellow fever mosquito conquered the world | Science | AAAS
www.science.org/content/arti...
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How the yellow fever mosquito conquered the world
Aedes aegypti further adapted to life around humans when it arrived in the Americas, study of hundreds of mosquito genomes reveals
https://www.science.org/content/article/how-yellow-fever-mosquito-conquered-world
about 2 months ago
0
1
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Genomic clues into the spread of deadly mosquitoes | Science
www.science.org/doi/10.1126/...
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Genomic clues into the spread of deadly mosquitoes
Ancient and more recent human interactions shape mosquito vector evolution
https://www.science.org/doi/10.1126/science.aea9024?utm_source=sfmc&utm_medium=email&utm_content=alert&utm_campaign=SCIeToc&et_rid=41055313&et_cid=5736120
about 2 months ago
0
2
0
reposted by
The Lambrechts Lab
Vasilakis Lab
about 2 months ago
1206 genomes reveal origin and movement of Aedes aegypti driving increased dengue risk | Science
www.science.org/doi/10.1126/...
. A seminal paper of great interest to all. Great work and congratulations to the team!
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1206 genomes reveal origin and movement of Aedes aegypti driving increased dengue risk
The emergence and global expansion of Aedes aegypti puts more than half of all humans at risk of arbovirus infection, but the origin of this mosquito and the impact of contemporary gene flow on arbovi...
https://www.science.org/doi/10.1126/science.ads3732
0
8
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reposted by
The Lambrechts Lab
Didier Mazel
about 2 months ago
Striking and frightening 😒 "They found multiple instances of insecticide-resistance variants in this malaria vector, although most of these weren’t shared with museum specimens collected as recently as 1967, suggesting rapid emergence"
www.science.org/doi/10.1126/...
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Genomic diversity of the African malaria vector Anopheles funestus
Anopheles funestus s.s. is a major human malaria vector across Africa. To study its evolution, especially under vector control pressure, we sequenced 656 modern specimens (collected 2014 to 2018) and ...
https://www.science.org/doi/10.1126/science.adu3596?utm_source=sfmc&utm_medium=email&utm_content=alert&utm_campaign=SCIeToc&et_rid=35361304&et_cid=5736120
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ScienceAdviser: Mosquitoes seem to love hedonists | Science | AAAS
www.science.org/content/arti...
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ScienceAdviser: Mosquitoes seem to love hedonists
Today in Science and science: How corpse flowers make a big stink, a rocky start for the ocean, and more
https://www.science.org/content/article/scienceadviser-mosquitoes-seem-love-hedonists
about 2 months ago
0
1
0
reposted by
The Lambrechts Lab
Le Monde
about 2 months ago
Chikungunya : forte hausse des cas autochtones en métropole, Santé publique France appelle à la vigilance face aux moustiques tigres
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Chikungunya : forte hausse des cas autochtones en métropole, Santé publique France appelle à la vigilance face aux moustiques tigres
L’implantation du moustique tigre dans 81 départements métropolitains inquiète les autorités, qui redoutent une propagation accrue du chikungunya et d’autres maladies vectorielles cet automne.
https://www.lemonde.fr/planete/article/2025/09/17/chikungunya-forte-hausse-des-cas-autochtones-en-metropole-sante-publique-france-appelle-a-la-vigilance-face-aux-moustiques-tigres_6641594_3244.html
0
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reposted by
The Lambrechts Lab
Nature
about 2 months ago
Brazil hopes to turn the tide of dengue with a home-grown vaccine and an army of mosquitoes
go.nature.com/41VWT1V
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How billions of hacked mosquitoes and a vaccine could beat the deadly dengue virus
Outbreaks of dengue are killing thousands of people in South America each year and getting worse. Brazil hopes to turn the tide with a home-grown vaccine and an army of mosquitoes infected with Wolbachia bacteria.
https://go.nature.com/41VWT1V
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Mosquito-borne viruses surge in a warming Europe | Science | AAAS
www.science.org/content/arti...
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Mosquito-borne viruses surge in a warming Europe
Chikungunya cases break records in France; West Nile virus appears near Rome
https://www.science.org/content/article/mosquito-borne-viruses-surge-warming-europe?utm_source=sfmc&utm_medium=email&utm_content=alert&utm_campaign=SCIeToc&et_rid=41055313&et_cid=5730218
about 2 months ago
0
1
1
reposted by
The Lambrechts Lab
Sarah Merkling
2 months ago
@elodiecouderc.bsky.social
is on 🔥 this month ! Our review (which the literature really missed, imho) giving an historical perspective on the methods used to study of mosquito-virus interactions in now online at
@cp-trendsmicrobiol.bsky.social
. Check it ou here:
www.cell.com/trends/micro...
add a skeleton here at some point
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6
2
reposted by
The Lambrechts Lab
Sarah Merkling
2 months ago
Virology lost one of his monuments, David Baltimore. To learn more about him and his contributions, I recommend (re)-listening to this great TWIV episode :
www.microbe.tv/twiv/twiv-10...
add a skeleton here at some point
0
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5
reposted by
The Lambrechts Lab
Elodie Couderc
2 months ago
New
#review
out 🚨 for mosquito enthusiasts 🦟 ! Have you ever questioned the approach you routinely use to investigate
#mosquito-virus
#interactions
? ⬇️
www.sciencedirect.com/science/arti...
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Does
#dengue
virus hijack
#mosquitoes
' brain? Study led by Felix Hol
@pasteur.fr
discovered that infected mosquitoes take smaller blood meals. As a result, they bite more often, and potentially infect infect more people. (video in French with English subtitles available)
youtu.be/2u_qckfAQa4?...
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La dengue aux commandes
YouTube video by Institut Pasteur
https://youtu.be/2u_qckfAQa4?si=JaLTa6iP6p09KD7-
2 months ago
0
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8
reposted by
The Lambrechts Lab
bioRxivpreprint
2 months ago
Blood, sweat, and beers: investigating mosquito biting preferences amidst noise and intoxication in a cross-sectional cohort study at a large music festival
https://www.biorxiv.org/content/10.1101/2025.08.21.671470v1
0
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reposted by
The Lambrechts Lab
Elodie Couderc
2 months ago
🚀 Excited to share (with a little delay) my first first-author publication on
#Vago
genes in
#mosquitoes
! 🦟 🦠 Have a look to see how we questioned a mosquito immunity dogma and challenged the existing understanding of Vago-like genes as antiviral factors ⬇️
bmcbiol.biomedcentral.com/articles/10....
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Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes - BMC Biology
Background Arthropod-borne viruses (arboviruses) such as dengue virus (DENV) and Zika virus (ZIKV) pose a significant threat to global health. Novel approaches to control the spread of arboviruses foc...
https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-025-02325-5
1
20
15
🦟🦠 Check out our latest article in
@natcomms.nature.com
on the genetic basis of
#dengue
virus susceptibility in
#mosquitoes
! Collaborative work brillantly led by
@merklinglab.bsky.social
and
@elodiecouderc.bsky.social
@pasteur.fr
and primarily supported by
@agencerecherche.bsky.social
rdcu.be/eBbg7
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Dengue virus susceptibility in Aedes aegypti linked to natural cytochrome P450 promoter variants
Nature Communications - Genetic factors affecting Aedes aegypti susceptibility to dengue virus infection aren’t well studied. Here the authors show that a cytochrome P450 gene, typically...
https://rdcu.be/eBbg7
3 months ago
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reposted by
The Lambrechts Lab
Cassandra Koh 🦟🔬🧪
3 months ago
📣 I'm recruiting a postdoc researcher to join my team for a project on mosquito-specific viruses and host interactions. Peep the job description & how to apply below. Perfect for soon-to-be or recent PhD graduates in mosquito vector biology 🦟 or arbovirology 🦠 🗓️ Application deadline 31 August 2025
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reposted by
The Lambrechts Lab
Le HuffPost
3 months ago
Moustiquaire ou citronnelle ? Comment se protéger vraiment des moustiques
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Moustiquaire ou citronnelle ? Comment se protéger vraiment des moustiques
https://www.huffingtonpost.fr/life/video/moustiquaire-ou-citronnelle-comment-se-proteger-vraiment-des-moustiques_253157.html
0
6
3
reposted by
The Lambrechts Lab
Hugo Perdomo
3 months ago
How can mosquitoes tolerate viral infections? In our latest preprint we show that mosquitoes that can regulate their metabolism after infection can tolerate viral infections better. Thanks to all the authors for all your ideas and contributions
www.biorxiv.org/content/10.1...
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Metabolic homeostasis favors tolerance to persistent viral infection in Aedes aegypti mosquitoes
The mosquito Aedes aegypti harbors a wide range of persistent viral infections, including both medically important arboviruses and insect-specific viruses (ISVs). However, the mechanisms underpinning ...
https://www.biorxiv.org/content/10.1101/2025.07.23.666353v1
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reposted by
The Lambrechts Lab
brackneylab
4 months ago
Despite all the shit going on, we have to celebrate our victories. New publication with
@entomososwin.bsky.social
and
@vectorimmunity.bsky.social
showing that hemocytes play a central role in disseminating flaviviruses to secondary tissues potentially functioning as a Trojan Horse(TBD)
rdcu.be/euj4g
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Mosquito immune cells enhance dengue and Zika virus infection in Aedes aegypti
Nature Communications - Infection of mosquito immune cells by dengue and Zika virus enhances the spread of virus infection to mosquito tissues, such as the salivary glands, to promote virus...
https://rdcu.be/euj4g
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reposted by
The Lambrechts Lab
Nathan Grubaugh
5 months ago
Interested in using phylogenetics to study arboviruses? Our new review in
@natrevgenet.nature.com
by
@viralverity.bsky.social
,
@sdellicour.bsky.social
, and Marta Giovanetti has you covered! 📖 👉
rdcu.be/epH2U
Short 🧵
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reposted by
The Lambrechts Lab
Simon Cauchemez
5 months ago
Just few days left to apply to one of these postdoc positions in my infectious disease modelling Unit at
@pasteur.fr
in Paris!
add a skeleton here at some point
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reposted by
The Lambrechts Lab
Siân Owen
5 months ago
The Wadsworth Center is expanding it's research focus on
#virology
/vector-borne diseases!
www.asmcareerconnections.org/job/research-scientist-5-g-31/78488664/
This is a unicorn assistant prof equivalent position with 12-month hard money salary and no teaching commitments (!) Reposts appreciated 🙏
3
49
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reposted by
The Lambrechts Lab
Clement Vinauger
5 months ago
🚨New preprint from the lab! Work led by our talented former postdoc
@karthikeyanc.bsky.social
where we show that incomplete larval control can make things worse by producing bigger and meaner adult mosquitoes that are more efficient vectors of Zika. See thread below
www.biorxiv.org/content/10.1...
add a skeleton here at some point
1
5
2
reposted by
The Lambrechts Lab
Sinead English
5 months ago
Interesting study! How the thermal tolerance of Aedes mosquito eggs varies depending on urbanisation - shows how critical developmental periods can facilitate adaptation to novel environments. Work from Souvik Chakraborty,
@joshuabenoit.bsky.social
& others
www.sciencedirect.com/science/arti...
🧪
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Thermal tolerance of Aedes aegypti mosquito eggs is associated with urban adaptation and human interactions
Climate change will profoundly affect mosquito distributions and their ability to serve as vectors for disease, specifically with the anticipated incr…
https://www.sciencedirect.com/science/article/pii/S030645652500124X?casa_token=WzcuZaiwjk4AAAAA:Gea0tDzDthyZJlRd101kClXE84fr5kZywlbQG0ryTrxxfApbMa9vzITB2PoVJzOgoq5XSvCc#undfig1
1
13
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reposted by
The Lambrechts Lab
Gael Cristofari
4 months ago
🦟 Bioinformatics Research Scientist position open in my lab in Nice (FR) to study Aedes mosquito retrotransposons & their interactions with arboviruses collab w/
@salehlabparis.bsky.social
&
@lambrechtslab.bsky.social
Apply:
euraxess.ec.europa.eu/jobs/359830
Please boost!
#ArboRetro
#Bioinformatics
0
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reposted by
The Lambrechts Lab
Science Magazine
5 months ago
A new Science study shows that the mycobacterium M. lepromatosis infected humans in the Americas before European contact. The findings reshape current views of leprosy in the Americas and provide insights into the long-term interactions between humans and infectious diseases.
scim.ag/3HuEjGB
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49
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reposted by
The Lambrechts Lab
Nature
5 months ago
A small genetic change makes the bacterium that caused the plague less fatal but possibly more transmissible
https://go.nature.com/43xhpG1
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Black Death bacterium has become less lethal after genetic tweak
Reducing the number of copies of one gene in the pathogen could also make it more transmissible.
https://go.nature.com/4dHyVfp
0
26
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reposted by
The Lambrechts Lab
Gytis Dudas
7 months ago
We're looking for a PhD student to join us at Vilnius University in Lithuania. We work on RNA virus evolution computationally but we'd like to generate more mosquito RNA virus sequence data. Official ad:
www.gmc.vu.lt/en/doctoral-...
. Please share & continue reading if interested.
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reposted by
The Lambrechts Lab
Ben Longdon
10 months ago
Great looking group leader position at CNRS Strasbourg on host-pathogen interactions in insects
0
6
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Great new study from the Dickson lab
@utmb.bsky.social
reveals how the microbial environment of Aedes aegypti larvae affects
#ZIKV
transmission.
#Mosquitoes
raised in urban containers (plastic buckets) are more susceptible than those from forest habitats (coconut husks)
dx.plos.org/10.1371/jour...
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Reduced microbe abundance in an urban larval development container increases Aedes aegypti susceptibility to Zika virus
Author summary Aedes aegypti mosquitoes, which spread viruses like dengue and Zika, inhabit different environments within Africa. Ancestral forms of Ae. aegypti occupy forested habitats, while domesti...
https://dx.plos.org/10.1371/journal.ppat.1013154
6 months ago
0
4
1
Sheep serve as amplifying hosts of Japanese encephalitis virus, increasing the risk of human infection | Science Advances
www.science.org/doi/10.1126/...
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Sheep serve as amplifying hosts of Japanese encephalitis virus, increasing the risk of human infection
Sheep serve as amplifying hosts for transmission cycle of JEV, increasing the public health risk of human infection.
https://www.science.org/doi/10.1126/sciadv.ads7441?utm_source=sfmc&utm_medium=email&utm_content=alert&utm_campaign=ADVeToc&et_rid=41055313&et_cid=5617764
6 months ago
0
2
0
Mosquito-borne viral disease sweeping Indian Ocean islands | Science | AAAS
www.science.org/content/arti...
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Mosquito-borne viral disease sweeping Indian Ocean islands
Safety issues with the only available vaccine complicates response to chikungunya
https://www.science.org/content/article/mosquito-borne-viral-disease-sweeping-indian-ocean-islands?utm_source=sfmc&utm_medium=email&utm_content=alert&utm_campaign=SCIeToc&et_rid=41055313&et_cid=5616351
6 months ago
0
1
1
Our paper is now published in its final form:
rdcu.be/elV6u
@biomedcentral.bsky.social
@salehlabparis.bsky.social
@merklinglab.bsky.social
@pasteur.fr
add a skeleton here at some point
6 months ago
0
16
8
Exciting Opportunity! The Mouse Genetics Lab
@institutpasteur.bsky.social
is seeking a
#postdoc
researcher to explore the genetic determinants of Zika virus transmission in
#mice
and
#mosquitoes
. Join us in advancing public health research with cutting-edge resources!
#Virology
#Genetics
#ZIKV
🦠🔬
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Post-doctoral position on host-vector transmission of Zika virus using mouse models - Research
The Mouse Genetics Laboratory is recruiting a post-doctoral fellow to study the role of host genetic determinants in the transmission of Zika virus between mice and mosquitoes in a collaborative proje...
https://research.pasteur.fr/en/job/post-doctoral-position-on-host-vector-transmission-of-zika-virus-using-mouse-models/
6 months ago
1
18
15
reposted by
The Lambrechts Lab
SalehLab
7 months ago
Thrilled to receive
@anrs-mie.bsky.social
grant with
@lambrechtslab.bsky.social
&
@retrogenomics.bsky.social
! Making mosquitoes intolerant to arboviruses. Thanks
@pasteur.fr
,
@inserm.fr
&
@cnrs.fr
for support. Exciting times for
#ARBORETRO
project! Stay tunned.
5
43
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reposted by
The Lambrechts Lab
8 months ago
did adaptations to humans leave traces in the genome of Aedes aegypti? check out our paper out today in Nature Ecology and Evolution. a BIG thanks to all the collaborators around the world that made this possible.
doi.org/10.1038/s415...
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https://doi.org/10.1038/s41559-025-02643-5
0
5
2
reposted by
The Lambrechts Lab
9 months ago
Do you want to know if global warming will impact how mosquito respond to viral infection? check our latest publication in Communications Biology
rdcu.be/d8wse
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Prolonged exposure to heat enhances mosquito tolerance to viral infection
Communications Biology - Single versus multi-generational exposure to increased temperature alters mosquito immune response to viral infection, with implications for mosquito-virus interactions...
https://rdcu.be/d8wse
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www.lemonde.fr/en/opinion/a...
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'The US's healthcare decisions pose serious threats to scientific progress and cooperation'
OP-ED. A group of researchers, doctors and NGO representatives express their concern about the Trump administration's initial measures, and point out that international cooperation is vital to tackle ...
https://www.lemonde.fr/en/opinion/article/2025/02/15/the-us-s-healthcare-decisions-pose-serious-threats-to-scientific-progress-and-cooperation_6738195_23.html
8 months ago
0
0
1
Boost your knowledge of pathogen-carrying arthropods with the “Medical Entomology” MOOC from Institut Pasteur! Enroll now on FUN and explore how vectors transmit pathogens and impact public health:
www.fun-mooc.fr/en/courses/m...
#Entomology
#MOOC
#PublicHealth
@pasteur.fr
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Medical Entomology
Which mosquitoes transmit malaria? Is the tiger mosquito the vector of the Zika virus? How is the transmission going? Find answers in the MOOC "Medical Entomology".
http://www.fun-mooc.fr/en/courses/medical-entomology/
8 months ago
0
8
5
reposted by
The Lambrechts Lab
Olivia Goldman PhD
8 months ago
I am thrilled to present the Mosquito Cell Atlas! We analyzed 367K nuclei from 19 tissues in male & female mosquitoes, creating a comprehensive resource for vector biology & infectious disease research. Plus we made some surprising discoveries! 🦟🧵
biorxiv.org/content/10.1...
1/n
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