Reproducible Human Reward Imaging Phenotypes Exhibit Differential Sensitivity to Dopamine D2 Receptor Antagonism https://www.biorxiv.org/content/10.64898/2026.05.14.724267v1

Recent preprint with Oriel FeldmanHall and Matt Nassar, showing clear neural evidence that adolescent (13-15 yrs) social media and smartphones use are associated with blunted reward signaling in the ventral striatum, the brain's reward processing hub, and worse mental health. osf.io/preprints/ps...

Selecting an effect size for power analysis is hard. Many researchers fall back on Cohen's thresholds, but they have no empirical basis and vary wildly by field. Our new paper offers a better option: field-specific effect size distributions built from meta-analytic data doi.org/10.3758/s134...

🚨Preprint Alert 🧠 Our new preprint „Menarche onset is an inflection point for mental health and brain development“ is now online! 👉 Preprint available here: www.biorxiv.org/content/10.6...

Very excited to announce our new preprint, led by @hollysully.bsky.social, that presents, benchmarks, and validates a method to estimate brain iron content from routine fMRI scans! It comes complete with a BIDS app! Check out the preprint and thread below! doi.org/10.64898/202...

Our new paper asks whether autism is linked to the way people learn from rewards. We’ve previously shown that people not only learn to value the features that predict reward, but also assign credit to features of their actions that they know are irrelevant (in this case, the card's location).

🚨Preprint Alert🚨 Our new preprint 'A Scalable fMRI Estimate of Basal Ganglia Brain Tissue Iron for Use in Developmental and Translational Neuroscience' is live!! lnkd.in/gpG9naba

Minneapolis has by far the most interesting Lyft rides convos of any of the cities I’ve lived in

Precision reward/affect fMRI study out now in HBM! onlinelibrary.wiley.com/doi/10.1002/... @dvsmith.bsky.social @olinotom.bsky.social @coopersharp.bsky.social and @shenghanwang.bsky.social Intensively sampled task + rest fMRI data with behavioral manipulation openly available on OpenNeuro! (1/2)

USPS announced that it would no longer postmark mail automatically on the date it is received. Voting rights advocates fear that this may end up disenfranchising voters who rely on postmark dates, and they’re urging people to get ahead of election deadlines.

🚨 New preprint alert! 🚨 Transdiagnostic latent factor models of psychopathology are widely assumed to improve brain-behaviour associations. So we decided to test this directly and found that they don't. A short 🧵 Link: www.biorxiv.org/content/10.6... 1/10

New preprint from the lab! Led by @martingell.bsky.social . There is something for everyone: brain-behavior prediction, latent variable modeling, test-retest reliability. 🧠📈📊 "Disentangling Brain-Psychopathology Associations: A Systematic Evaluation of Transdiagnostic Latent Factor Models"

Excited to share our latest paper in which we discuss merging theory-and data- driven computational psychiatry in a large transdiagnostic cohort study (N=2400) www.biologicalpsychiatrycnni.org/article/S245... Christopher Pittenger, Godfrey Pearlson @annierhcheng.bsky.social @sobp-org.bsky.social

🚨🚨New paper day!🚨🚨 Wonderful work from the longitudinal arm of our cannabis-users study showing how brain reward-system function changes over 12 months in regular users. 🧵⬇️ #neuroskyence www.nature.com/articles/s41...

🚨📃New Wassum Lab Paper 📃🚨 Out today, Melissa Malvaez, Nick Griffin, Andrea Suarez & team discovered that dopamine can enable reward predictions to shape how we pursue reward. Surprisingly, we find that dopamine can constrain instrumental reward seeking. www.jneurosci.org/content/46/8... 🧵👇🏻

#eNeuro: Findings in rats from Boven et al. reveal that the cerebellum doesn't just fine-tune our movements but can also actively compute our internal sense of time, helping link between what we perceive and how we act. https://doi.org/10.1523/ENEURO.0198-25.2025

#eNeuro: Findings from Soma et al. reveal how reward-related information is hierarchically distributed across the rat's brain. https://doi.org/10.1523/ENEURO.0256-25.2026

OK I swear a saw a cartoon about a mediation analysis being 3 correlations in a trench coat but I can't find it and searching online just gives me a lot of trench coats 😂 does anyone have this? @dingdingpeng.the100.ci in my mind you were involved but I might have made it up

Rent assistance is a HUGE need right now. People have drained their savings in hiding for months and now they’re losing their homes too. If you need ideas about where to send your money:

Can you easily distinguish between value, valence, and salience? Probably not, but the prefrontal cortex of mice seems to achieve this by creating a sort of multidimensional orthogonal neural space, where each dimension corresponds to one of these subjective elements www.nature.com/articles/s41...

So excited that this textbook, edited by @dfareri.bsky.social @dvsmith.bsky.social & @thepsychologist.bsky.social is out now! And so happy to have been invited to contribute. Here’s my chapter on the role of memory, esp. semantic memory, in temporal discounting: link.springer.com/chapter/10.1...

New paper in Imaging Neuroscience by Nina Raduner, Silvia Brem, et al: Neural and behavioural differences in multisensory statistical and reinforcement learning across development and task variants doi.org/10.1162/IMAG...

www.nbcnews.com/news/us-news... Watch MADDOW "IF THEY BUILD THEM THEY WILL FILL THEM" This detention center is at Fort Bliss near El Paso TX. Houses roughly 3K human beings They're in TENTS Horrendous conditions 3 PEOPLE DIED THERE, ONE DEATH now a homicide Call Your Reps PLS 202 224-3121

The extended version of my thesis procrastination project/subcortex visualization package is out now in both Python and R, now that I’ve graduated 🤠 This figure shows the 9 atlases included (and counting)! Preprint: www.biorxiv.org/content/10.6... Website: anniegbryant.github.io/subcortex_vi...

in an ideal world the trauma this couple went through *shouldnt* resonate stronger than a latino family terrorized by ice. but we dont live in that world. we live in the real world. so i applaud it when the most minnesota people possible link arms with us and FIGHT like this.

Love to see leaders using their platforms for good. Check out the links in this thread for ways to help in Minneapolis!

Let’s do better. Links to other victims of ICE/CBP God Fund Me sites are provided in the comments. Please R/T.

How many versions of the Iowa Gambling Task (IGT) exist? And how much does this affect research using the IGT? More than you might think. 🧵

The Iowa Gambling Task is an extreme example of Jingle Fallacy and schmeasurement. In 100 articles we found 244 different ways of scoring it, 177 were never reused. Correlations between them range -.99 to .99. At the same time, we show meta-analyses combine these results as if they’re equivalent.

A friend here in Minneapolis who knew Alex Pretti just texted our group that Alex was "super cool laid back and a great guy"

ICE agents beat and executed a man in public in Minneapolis this morning

NIH grant writing people, do you have thoughts on the use of "I statements" in F fellowships and K training grant apps? I thought someone told me once to use "I will", "I propose" in training-focused apps to emphasize independence, but maybe it sounds arrogant?

Another friend put it to me like this: "ICE has made the classic Nazi mistake. They've invaded a winter people in the winter."

Why in the world are we not screening all pregnant people for iron deficiency when we know it’s associated w/ bad outcomes for mom & baby, affects the vast majority of pregnancies & is easily diagnosed & treated?! Oh I forgot. We don’t care about women or children. tinyurl.com/Ironpreg

something light

New paper in @acamh.bsky.social's JCPP! We found that early adversity doesn't affect positive emotions uniformly-- youth follow 4 distinct developmental trajectories. & This heterogeneity matters for understanding depression/anxiety risk. 🧵 1/5 📊 Paper: acamh.onlinelibrary.wiley.com/doi/10.1111/...

Excited for the 1st lab paper to be live @biologicalpsych.bsky.social ! @emilyrperkins.bsky.social @keananjoyner.bsky.social and I discuss testing biology as simultaneous + unique predictors of different levels of psychopathology hierarchies 1/7🧵 www.biologicalpsychiatryjournal.com/article/S000...

Walz: "What's happening in MN defies belief. News reports simply don't do justice to the level of chaos & disruption & trauma the federal govt is raining down... This long ago stopped being a matter of immigration enforcement. Instead, it's a campaign of organized brutality against the people of MN"

New Stage 2 RR published in Clinical Psych Science: doi.org/10.1177/2167... contrary to what some claim, urgency DOES NOT moderate associations between affect and alcohol/cannabis use in EMA data. Take a look for a comprehensive test of this idea and let us know what you think!

Amazing, not only the mPFC encoded categorical scales, but also it did it independently of linguistic similarity, suggesting construct-sensitive integration during self-report and a neural basis for psychological assessment. #cogpsyc #cognition #perpsy #socialpsyc

New paper & a thread on the results 👇 ‘Reward-specific learning parameters change across normative adolescent development and are blunted in youth with high risk for depression’ acamh-onlinelibrary-wiley-com.ezp3.lib.umn.edu/doi/full/10....

🚨My trainee Victoria Murphy, data architect Gabriel Mongefranco, and I are pleased to share 🌟EMA-CleanR: R code to pre-process, clean, and visualize ecological momentary assessment (EMA) data! Documentation: teamdynamix.umich.edu/TDClient/210... Code: github.com/DepressionCe...

It’s 1990, I’m 1 years old, and the republican president of the US is attacking a petrol state It’s 2004, I’m 15 years old, and the republican president of the US is attacking a petrol state It’s 2026, I’m 37 years old, and the republican president of the US is attacking a petrol state

#RewardSignals #neuroskyence

#RewardSignals #neuroskyence

½ New preprint shows cue-evoked phasic dopamine in the NAc tracks persistent incentive salience, not outcome value updates. In ST rats under omission, dopamine remained high for cues even as reward was cancelled, mirroring persistent attraction #RewardSignals #neuroskyence doi.org/10.64898/202...

Way back in 1999, Kenji Doya sketched a big picture theory of the brain: 1️⃣The cerebellum is specialized for supervised learning 2️⃣The basal ganglia are for reinforcement learning 3️⃣The cerebral cortex is for unsupervised learning How does this hold up in 2026? www.sciencedirect.com/science/arti...

Post a perfect album from the 90s that isn't nirvana, soundgarden, pearl jam, or alice in chains.

Do people judge what is going to happen in unknown situations differently depending on their socioeconomic position? Yes, if you experience lower socioeconomic position, you think the big rewards are even more unlikely to come your way: www.sciencedirect.com/science/arti...