Risk of suicidal behavior is higher just before and, to a lesser extent, during ADHD medication treatment compared to off-treatment in individuals with ADHD.

Psilocybin and MDMA promote adult oligodendrocyte and myelin plasticity.

Increased reactive astrocyte activity in the medial orbitofrontal cortex underlies cognitive impairments in schizophrenia.

"Polygenic risk scores for internalizing, neurodevelopmental, and addiction-related traits index multiple distinct behavioral mechanisms with specific relevance to adolescent psychopathology risk."

If anyone would like to help organize the SOBP BrainHack 2026, please let me know ASAP! (especially folks with affiliations at NYC institutes where we might be able to book a space for the hackathon)

Lifetime physical activity moderates the association between childhood adversity and functional connectivity, with higher physical activity linked to connectivity profiles consistent with resilience.

"Immuno-metabolic depression is characterized by a distinct, multimodal neuro-demographic signature involving cortico-limbic circuitry"

Marijuana use is linked to functional connectivity while alcohol use is linked to cognition in youth.

Grateful to @biologicalpsych.bsky.social for highlighting our work on fear vs. emotional pain in PTSD, from symptom networks to neural signatures. Open access for 60 days 👇 doi.org/10.1016/j.bi...

Age and duration of illness are important to consider in developmental models of major depression.

"Sensory phenotypes in autism correspond to differences in functional connectivity across cortical, subcortical, and network levels."

Reduced brain energy metabolism due to post-COVID condition is linked to cognitive impairment.

Mania and bipolar have distinct genetic profiles, with mania capturing a core genetic component of bipolar disorder distinct from depression.

Neural responses to unexpected stimuli in infants is linked to anxiety risk.

"Genomic research on suicidality in Latin America is growing but remains fragmented and underpowered. Increasing representative sampling, implementing ancestry-aware methods, and fostering collaborations are essential to advance research and inform prevention strategies in these populations."

Our next Editor Spotlight features Dr. Anissa Abi-Dargham, who serves as a Deputy Editor for Biological Psychiatry. Check out what she has to say about selecting manuscripts for the journal and advice for first-time authors.

Atypical depression has distinct risk profiles and antidepressant responses compared to adults with other depressive disorders.

🚨Thrilled to share I am able to hire someone (PhD preferred) with coding expertise to work on our HAPPE software for EEG! Knowledge of Matlab, Python, and EEG signal processing required. Enthusiasm for teaching/mentoring, collaboration, and developmental science preferred!

Looking for a postdoc in #computationalpsychiatry? Apply here to join an interdisciplinary team and work with a large longitudinal transdiagnostic dataset postdocs.yale.edu/posts/2026-0... @RobbRutledge @xiaosigu @DrChrisPitt @PearlsonGodfrey @ACNPorg @YaleMed

Save the date for the annual "Neural Circuits and Behaviour" satellite conference at the Canadian Association for Neuroscience annual meeting, cohosted by @franklandlab.bsky.social and myself on May 18, 2026. We have a great speaker lineup and will be selecting 4 trainees talks from our registrants!

Over the next two weeks, our Social Media Editor will be sharing highlights of her adventures as a travelling human phantom for a psychiatry research study! Be sure to follow along on our Instagram:

Our first Editor Spotlight features Dr. John Krystal, who serves as the Editor for Biological Psychiatry. Check out his thoughts on emerging trends in psychiatric research and his advice for first-time authors. Stay tuned for more insights from our editors!

🚨 I'm searching for a full-time research coordinator to join my group & work on precision brain 🧠 network and cognitive control projects at both 3T and 7T. Please rt 🙌 Applications due: Feb. 26 Start date: flexible, as early as June More 👇 #neuroskyence #PsychSciSky

Over the next few months, we’ll be highlighting our Biological Psychiatry editors and sharing some of their insights on publishing! Follow along for a behind-the-scenes look at our editorial process and some helpful tips as you prepare your manuscripts. 🧠🧬📝 Instagram: biologicalpsych LinkedIn ⬇️

Now online in @biologicalpsych.bsky.social CNNI - our paper showing that reliance on habitual responding in transdiagnostic compulsivity may be underpinned by uncertainty about learned environmental structure 📃 www.sciencedirect.com/science/arti...

We’ve got some fun content coming your way in the coming weeks so make sure you’re following us on here, LinkedIn, and Instagram!

Findings in this @biologicalpsych.bsky.social CNNI paper are complementary to other results published using graph theory metrics in @braincomms.bsky.social. Check out this 20 minute lecture by Christi Westlin that connects the two papers! 8/8 youtu.be/0Zjs-7lf6fA academic.oup.com/braincomms/a...

Sharing @biologicalpsych.bsky.social CNNI study: Westlin et al. gradient mapping paper in 187 subjects [64 FND, 62 PCs, 61 HCs]. New mechanistic insights delineated in the paper - as well as summarized here 1/n @yutakatsumi.bsky.social @mgbresearch.bsky.social sciencedirect.com/science/arti...

Excited for the 1st lab paper to be live @biologicalpsych.bsky.social ! @emilyrperkins.bsky.social @keananjoyner.bsky.social and I discuss testing biology as simultaneous + unique predictors of different levels of psychopathology hierarchies 1/7🧵 www.biologicalpsychiatryjournal.com/article/S000...

Very excited to share our latest 📖 publication from the Latin American Genomics Consortium Suicide Working Group, now in press in @biologicalpsych.bsky.social, where we systematically review genomic 🧬 studies of suicidality in Latin American populations: linkinghub.elsevier.com/retrieve/pii...

Does pubertal development influence the effects of socioeconomic disadvantage💲 on neurodevelopment🧠 and internalizing behaviors😞 , and are these effects sex-specific♂️♀️ ?

How does a novel polygenic risk score 🧬, serving as an index for somatostatin-expressing neuron vulnerability ⚠️, associate with the severity of depressive symptoms 📈 and cognitive decline 📉 in individuals with late-life depression 👴, and are these effects sex-specific ♂️♀️?

Across studies of deep brain stimulation for treatment-resistant depression, how is treatment-resistant depression 🚫 defined, how are deep brain stimulation 🧠⚡ targets identified, and how do these associate with specific symptom dimensions?

How do polygenic scores 🧬 for schizophrenia and major depression associate with traits like smoking 🚬 and BMI ⚖️ in Chinese adults 🇨🇳 compared to European populations 🌍, and can this be used to establish a role for sociocultural factors 🤝?

Can changes in hierarchical brain dynamics 🧠🔄 serve as a common biomarker 🎯 for remission ✨ from Major Depressive Disorder 😔 across various therapeutic interventions 💊🗣️?

Does PTSD diagnosis and severity affect cortical gyrification of the prefrontal cortex 🧠 ?

What are the transdiagnostic and disorder-specific 🎯 genetic effects 🧬 driving the associations between psychopathology 😔 and cognitive functioning 💡 across development?

Can the shared genetic architecture 🧬 between metabolic traits and anorexia nervosa explain the mechanisms that contribute to their biological link 🔗 ?

How does body dysmorphic disorder affect brain structure and function in the occipital-fronto-limbic circuit 🧠🕸️ ?

How do theta oscillations 🧠 differ in individuals at clinical high-risk for psychosis ⚠️, can they predict psychosis conversion ➡️, and do they relate to deficits in mismatch negativity 🔗?

How does pretreatment brain activation ⚡ in prefrontal and cingulate regions 🧠 moderate the effectiveness of exposure-focused CBT 🎯 versus relaxation training 🧘 for pediatric anxiety 👧😟?

Can we use a vocal biomarker 🗣️ to effectively enrich participants in antipsychotic clinical trials💊 for schizophrenia 🧠, leading to enhanced treatment outcomes ✨, reduced sample sizes 📉, and reduced costs💲?

How can we integrate multi-omic 🧬 data 📊 across blood 🩸 and brain 🧠 to help identify candidate molecular mechanisms 🔗 and novel drug targets 💊 for major depression 😔?

friendly reminder that if you are declining to review an article, please please please suggest alternative reviewers if you can!

How do age-related changes in the fear network influence PTSD risk and resilience in later life?

We're now also on Instagram - give us a follow and stay tuned for more visual content! www.instagram.com/biologicalps...

How does the neurophysiological response to perceived stress relate to suicide risk as well as cannabis and nicotine use in young adults with bipolar disorder?

How do steroid hormones modulate molecular systems to influence suicide risk throughout the menstrual cycle?

Objective estimates of drug-biased behavior outperform subjective drug use measures in predicting addiction treatment outcomes?! Read more about it in our new paper in @biologicalpsych.bsky.social GOS w/ @nataliemcclain.bsky.social @narcatms.bsky.social et al! www.sciencedirect.com/science/arti...

🧠 We're hiring! 🧠 Are you passionate about neuroscience and education? Join our faculty at UNC Chapel Hill to inspire and teach the next generation of neuroscientists. Apply now: 🔗​​https://unc.peopleadmin.com/postings/308455 #Neuroscience #TeachingJobs #AcademicJobs #HigherEd