📢PhD job alert! A exciting PhD project that involves using MEG and biophysical modelling to try to predict effects of a glutamatergic treatment for psychosis... plus you can develop your own side project. Join our great team! www.ucl.ac.uk/work-at-ucl/...

In a #ICML2026 position paper we argue a dynamical systems perspective is needed to drive time series models forward: arxiv.org/abs/2602.16864 For TS, we need to move away from transformers that do not respect a system’s dynamical structure, esp. if out-of-domain generalization & insight is sought.

Donoghue et al. introduce the Human Single-Neuron Pipeline, an open source processing pipeline for collecting and analyzing human single-neuron data: doi.org/10.52294/001... @ohbmossig.bsky.social @ohbmofficial.bsky.social #OpenDatasets #SpecialIssues

Super glad to have our team's work on clinical applications of neural simulations highlighted in this article! Trying to bring academic work to the real-world has been a great experience and I'm quite excited to continue these efforts with @dvwz.bsky.social and @jonescompneurolab.bsky.social

Layer-specific wide-field calcium imaging of neocortical activity https://www.biorxiv.org/content/10.64898/2026.04.28.721258v1

In people at high risk for psychosis, reduced excitability of pyramidal cells predicts who will later convert to develop psychosis, suggesting this may be a root cause of schizophrenia rather than a consequence of the illness.

New paper in Imaging Neuroscience by Lindsey Power, Sylvain Baillet, et al: A neuroscientist’s guide to neural burst detection doi.org/10.1162/IMAG...

Headed to #SOBP2026? Come visit our posters on stress and mental effort! F325: Investigating the Role of Serotonin in Stressor Controllability and Mental Effort Allocation (me!) S297: Learning and Generalization of Stressor Controllability for Mental Effort allocation (Tony El Nemer)

Really excited for this conference! We’ve all been digging deep into different ways to use EEG to better understand and treat psychiatric diseases If you’re at SOBP definitely stop by our posters if you want to chat biophysical mechanisms, biomarkers, and deep learning approaches to EEG analysis

New work, now out in PLoS Biology. Using intracranial recordings & EEG, we find that the human STN rapidly engages / releases motor inhibition depending on task context, does so in tight accord w/ frontal cortex, and shows little to no lateralization while doing so. journals.plos.org/plosbiology/...

[ #ICLR2026 ] How do we know if two systems are performing the same computation when they are constantly driven by different external inputs? 🧠🤖 I’ll be presenting our novel method InputDSA tomorrow April 23 (2:15pm-4:45pm EDT in Pavilion 3 P3-#1614)📍 Come swing by our poster! I’d love to chat!

Uncovering putative neural mechanisms of neurotherapeutic impacts on EEG using the Human Neocortical Neurosolver https://www.biorxiv.org/content/10.64898/2026.04.11.717895v1

Happy to share a new preprint from the @hnnsolver.bsky.social team!🧠💻🎉 "Uncovering putative neural mechanisms of neurotherapeutic impacts on EEG using the Human Neocortical Neurosolver" 📝 www.biorxiv.org/content/10.6...

New preprint! 🧠 How do RNNs learn abstract rules from sequences, independent of specific stimuli? By Vezha Boboeva, with Alberto Pezzotta & George Dimitriadis "From sequences to schemas: low-rank recurrent dynamics underlie abstract relational representations" www.biorxiv.org/content/10.6...

Thrilled to see the second paper of the lab out 🤩 Check it out if you need a method to infer causality from neural data, even when the signal is short! Paper: joss.theoj.org/papers/10.21... Code: github.com/CMC-lab/Tran...

Want a dataset to test ideas on neural basis of decision making or how areas interact as we make choices? Check out our data published today @rudebecklab.bsky.social. >16,000 single neurons from 22 anatomically confirmed areas in macaques performing a decision task. www.nature.com/articles/s41...

Really excited to share a new preprint! 𝗛𝗼𝘄 𝗱𝗼 𝗯𝗿𝗮𝗶𝗻𝘀 𝘀𝘁𝗮𝘆 𝗿𝗼𝗯𝘂𝘀𝘁 & 𝗲𝗳𝗳𝗶𝗰𝗶𝗲𝗻𝘁 𝘄𝗵𝗶𝗹𝗲 𝗯𝗲𝗶𝗻𝗴 𝗶𝗻𝗰𝗿𝗲𝗱𝗶𝗯𝗹𝘆 𝘀𝗽𝗮𝗿𝘀𝗲? We explore how! www.biorxiv.org/content/10.6... We built Connectome-based Neural Networks (CoNNs) using Drosophila wiring (larva&adult) & compared with random networks with same sparsity.

Preprint out arguing that we should build the techology to translate (compile) molecularly annotated connectomes into dynamics. I think this is incredibly important. arxiv.org/abs/2603.25713

This work started when Christian Pehle, @tonyzador.bsky.social, and I found that training sequentially (consuming/producing one spike at a time) in JAX was prohibitively slow. You certainly can consume multiple spikes in parallel—TLDR; just use an associative scan—but... 2/N

🧵 New preprint led by @bingbrunton.bsky.social, @elliottabe.bsky.social, @lawrencehu.bsky.social We gave a worm brain control of a fly body and it walked What did we learn? Nothing, other than deep reinforcement learning is effective We call it the digital sphinx www.biorxiv.org/content/10.6...

Our paper “Multifidelity Simulation-based Inference for Computationally Expensive Simulators” has been accepted at ICLR 2026! 🥳 We hope this can be a practical solution for anyone analysing and doing inference on computationally expensive simulators. Paper: openreview.net/pdf?id=bj0dc...

We have a new preprint examining single neuron responses in humans undergoing TMS (www.biorxiv.org/content/10.6...). The excellent Charlie Dickey led the way, and I had the privilege to co-supervise this work with @coreykeller.bsky.social and @aaronboes.bsky.social 🧵 (1/7) 🧠🟦 🧠💻

A Spatially Structured Spiking Network Model of Beta Traveling Waves and Their Attenuation in Motor Cortex https://www.biorxiv.org/content/10.64898/2026.03.18.712701v1

Pleased to share that our paper "Representation Biases: Variance is Not Always a Good Proxy for Importance" is now out as Theory/New Concepts paper in eNeuro! www.eneuro.org/content/13/3... 1/

Happy to share a new preprint from my PhD thesis! “A novel framework for expanding RNNs with biophysical detail to solve cognitive tasks” 🧠💻 📝 www.biorxiv.org/content/10.6... @jonescompneurolab.bsky.social

Deep-learning-assisted simulation of a cortical circuit: integrating anatomy, physiology and function https://www.biorxiv.org/content/10.64898/2026.03.13.711751v1

We've been saying for a while now that beta bursts might be functionally heterogeneous. Check out @quentinmoreau.bsky.social's paper where we show that different types of bursts have different relationships to behavior in a sensorimotor adaptation task 👇👇👇

Mission: record hippocampal place cells in zero gravity Crew: 3 rats with electrode arrays Vehicle: Space Shuttle Columbia Status: data now publicly available on DANDI, 28 years later The ratstronauts' mission is finally complete. 🐀🚀 h/t NASA about.dandiarchive.org/blog/2026/02...

underappreciated concept 🙂 for more dipoles: neighboring dipoles have different orientations & can have different stimulus preferences. so even though topographies look similar, subtle differences remain. maybe that's why it is possible to decode information from relatively few sensors?

The angle of the dipole obviously matters. If active dipoles in two conditions are slightly misaligned, a difference can be observed. However, this difference is not driven by differences in amplitudes, but only by differences in orientations. Here, I simulated such a scenario. #brainmovies

Excited to share our new findings: distinct neural dynamics in prefrontal and premotor cortex during flexible decision making, preprinted on biorxiv. www.biorxiv.org/content/10.6...

Do you have an open working memory dataset and want it to be findable and reused? You can now add it to the Open WM Data Hub: williamngiam.github.io/OpenWMData! The collection of datasets tagged with useful metadata is steadily growing thanks to a small team of volunteers!

Unit tests in research code feel like something that's slowing you down until they wind up saving you six months of suffering

PhD position in computational neuroscience/brain physics to work with us on biophysical modeling of electric and magnetic brain signals at University of Oslo as part of the Marie Curie EU project @neuronanotechdn.bsky.social. Application deadline: December 9th. www.jobbnorge.no/en/available...

📍Excited to share that our paper was selected as a Spotlight at #NeurIPS2025! arxiv.org/pdf/2410.03972 It started from a question I kept running into: When do RNNs trained on the same task converge/diverge in their solutions? 🧵⬇️

The Jones comp neuro lab is at #SfN25! Come check out our talks and posters to learn about our latest & greatest Science with HNN! All poster presentation times & locations can be found at jonescompneurolab.github.io/textbook/res...

Excited to release our new work: Petri Dish Neural Cellular Automata! pub.sakana.ai/pdnca We investigate how multi-agent NCAs can develop into artificial life 🦠 exhibiting complex, emergent behaviors like cyclic dynamics, territorial defense, and spontaneous cooperation.

No tricks, just brains in 3D 🧠🧟‍♂️ This cleared human brain slice (~10×7×0.3 cm) was imaged at 0.17 µm/pixel on the 3Di HOTLS lightsheet microscope. Sharp, transparent, undead-level perfection (Alpenglow Biosciences). #3Dtissueimaging #LightSheet #Halloween

Today at #PracticalMEEG2025 Nick @willenjoy.bsky.social and I will be conducting a tutorial on how to simulate EEG/MEG data with our toolbox meegsim. If you happen to be around, come to our virtual booth; we will tell scary stories.👻

Revised version of our #NeurIPS2025 paper with full code base in Julia & Python now online, see arxiv.org/abs/2505.13192

Check out our latest work led by @joeyzhou.bsky.social on alpha oscillatory networks in PLOS Biology! ➡️ journals.plos.org/plosbiology/... Do ongoing alpha activity fluctuations influence perceptual sensitivity or criterion?

🚨Postdoc job offer🚨 Are you interested in beta bursts? Want to help drive methods for laminar inference with MEG? Now hiring a postdoc: run head-cast MEG experiments, help build our laMEG toolbox, and collaborate across Lyon–Marseille–Strasbourg. emploi.cnrs.fr/Offres/CDD/U... Please repost! 🧠📈

Is the the neuroimaging community (broadly conceived) submitting to 𝗡𝗲𝘂𝗿𝗼𝗶𝗺𝗮𝗴𝗲 again????? Not to be publication police but the shift had seemed major 1-2 years ago. Looking at the editorial board it seems to have serious scientists once more. Curious about thoughts of the community.

𝗘𝗻𝗱 𝗼𝗳 𝘁𝗵𝗲 𝗲𝗺𝗽𝗶𝗿𝗲 𝗼𝗳 𝗻𝗲𝘂𝗿𝗼𝗻𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻?? Astrocytes in the regulation of fear memories! www.nature.com/articles/s41... #neuroskyence h/t @claeneuro.bsky.social

Can AI simulations of human research participants advance cognitive science? In @cp-trendscognsci.bsky.social, @lmesseri.bsky.social & I analyze this vision. We show how “AI Surrogates” entrench practices that limit the generalizability of cognitive science while aspiring to do the opposite. 1/

Thrilled to share our new preprint highlighting distinct neurocomputational mechanisms underlying how reward and punishment determine adaptive cognitive control - a massive fMRI study and collaborative team effort with the @shenhavlab.bsky.social 🧠 Link here: www.biorxiv.org/content/10.1...

Map of spiking activity underlying change detection in the mouse visual system https://www.biorxiv.org/content/10.1101/2025.10.17.683190v1

Definitely looking forward to helping run this workshop!

📜🎉 I'm happy to share that my review of clinical research investigating aperiodic neural activity is now published! It examines 177 reports of aperiodic activity in clinical disorders summarizing findings, discussion topics, & making some recommendations! onlinelibrary.wiley.com/doi/10.1111/...