New paper in CPsy - 'Computational Mechanisms of Approach-Avoidance Conflict Predictively Differentiate Between Affective and Substance Use Disorders' from Marishka Mehta and the group of @rssmith.bsky.social doi.org/10.5334/cpsy...

New paper in CPsy 📢 - from Mostafa Abdou, @raziasahi.bsky.social, Thomas Hull, @eriknook.bsky.social and @nathanieldaw.bsky.social - cpsyjournal.org/articles/10....

Delighted to share our work on replay and successor representations! We find replay during very short task pauses in human visual cortex that is linked to learning SRs & happens when learning is implicit. Study led by @lnnrtwttkhn.bsky.social #compneuro #neuroskyence www.pnas.org/doi/10.1073/...

Very happy to share my first preprint from @oxexppsy.bsky.social @oxneuro.bsky.social ! We (me + co-first authors @lilweb.bsky.social @mirunarascu.bsky.social + PI @mkflugge.bsky.social + many others) used transcranial focused ultrasound stimulation (TUS/tFUS/LIFU) of the human amygdala ... (1/15)

I still get chills Meet Mike *30+ years severe depression *first hospitalized @ 13y *20 meds *3 rounds of ECT *2 near-fatal suicide attempts Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE see videos, read paper, follow thread doi.org/10.31234/osf...

I’m elated to share our latest publication - out now in @natmentalhealth.nature.com! www.nature.com/articles/s44... - tour de force by @leahbanellis.bsky.social @brainandstomach.bsky.social and the rest of the VMP team!

Attractors are usually not mechanisms - new blog post: open.substack.com/pub/kording/...

Clinical research in England is wild! 3+ years, 20+ meetings, 200+ documents, 500+ emails is what it can take to open a fully funded, observational non-CTIMP study. Thank you @chrischirp.bsky.social and colleagues for calling attention to this urgent, solvable crisis! www.bmj.com/content/390/...

Thrilled to see our TinyRNN paper in @nature! We show how tiny RNNs predict choices of individual subjects accurately while staying fully interpretable. This approach can transform how we model cognitive processes in both healthy and disordered decisions. doi.org/10.1038/s415...

Our new study published in TheLancetPsych! We found that pramipexole augmentation substantially reduced depressive symptoms in patients with treatment-resistant depression over 48 weeks of treatment. This is an important advance in how we treat depression! 1/6 www.thelancet.com/journals/lan...

Looking forward to #RLDM2025! 🌀 I'll be talking about why we get caught in repetitive negative thinking patterns like rumination and worry at the Thursday poster session (poster #21) — come say hi if you're around!

I am so excited to share that our paper 'A neural basis for distinguishing imagination from reality' is now published in @cp-neuron.bsky.social! 🧠✨ See thread below! doi.org/10.1016/j.ne...

Fundamental work that everyone should read!

Completing the mouse, ANN, human trilogy of projects, here are two openings to study cognitive map deficits in human psychosis patients with the inimitable @mattnour.bsky.social Using functional neuroimaging and planning tasks. If you’re keen to join us then apply!

📢 Bühler Talks – Summer 2025 🧠 Jill O’Reilly (Univ. Oxford, UK) 🗣 “The representation, use and updating of priors in the human brain” 🕔 May 28, 5pm Zoom: tu-dresden.zoom-x.de/j/6464455404... @tudresden.bsky.social #BühlerTalks #TUdresden

Thank you @clairelavalley.bsky.social and @rssmith.bsky.social. Striking to see aversive pruning altered in people with methamphetamine use, particularly given the results in depression (dx.doi.org/10.1017/S003...).

New in Nature MentalHealth! with Vrizzi, Najar, Lemogne, and @mael-lebreton.bsky.social We tested whether behavioural and RL-based model parameters are test-retest reliable and predict mental health traits. The result? Not really. A cautionary tale for comp. psychiatry doi.org/10.1038/s442...

Huge congrats to @clairelavalley.bsky.social on this new paper. www.nature.com/articles/s41.... Results show that methamphetamine users show a specific deficit in model-based planning, in which they fail to simulate plans with large short-term losses (elevated aversive pruning). Brief thread below!

Often people with ephys data say it doesn’t look like any predictive coding signals, but this clever analysis says otherwise - nice work!

New preprint, w/ @predictivebrain.bsky.social ! we've found that visual cortex, even when just viewing natural scenes, predicts *higher-level* visual features The aligns with developments in ML, but challenges some assumptions about early sensory cortex www.biorxiv.org/content/10.1...

This is especially relevant to mental health neuroscience…

🤖🧠 Paper out in Nature Communications! 🧠🤖 Bayesian models can learn rapidly. Neural networks can handle messy, naturalistic data. How can we combine these strengths? Our answer: Use meta-learning to distill Bayesian priors into a neural network! www.nature.com/articles/s41... 1/n

V cool work

🔥💥📣 Excited to announce a new policy at the Computational Psychiatry (CPSY) journal @cpsyjournal.bsky.social. Starting from April 2025, CPSY will compensate reviewers for their time and effort invested in reviewing manuscripts. w/ @drrickadams.bsky.social cpsyjournal.org/articles/10....

Sharing a new paper from the lab. This paper, led by Sangyoon Ko, represents a merging of two longstanding research themes in the lab-- adult neurogenesis and systems consolidation. rdcu.be/el18q A short thread follows for those interested. 1/n

Impressive study in @nature from my colleague Marcus Stephenson-Jones at UCL in the @sainsburywellcome.bsky.social www.nature.com/articles/s41...

Super interesting work with a computational model of how auditory hallucinations may arise: journals.plos.org/plosbiology/... #neuroscience #compneuro

Don't miss our upcoming #SPM course for #EEG & #MEG online from 19-22 May 2025! 🧠 We'll cover preprocessing, source reconstruction, DCM & OPM analyses. Practicals will include SPM-Python! Programme: www.fil.ion.ucl.ac.uk/spm/docs/cou... Register by May 11th 👇 onlinestore.ucl.ac.uk/conferences-...

📢 Fantastic post doc job opportunity in my group and co-supervised by DeepMind's @mariaeckstein.bsky.social - now live! Ad here: tinyurl.com/26rafzdc - deadline May 29th. This is part of a very exciting collaboration with @melgaby.bsky.social and Matt Nour, funded by @wellcometrust.bsky.social.

1/15) We had an interesting conversation on BlueSky here last week about why there's not more of an interface between theory and experiments in neuroscience. Thanks to those who chimed in! My broader take is shown below. A🧵on the experience that led me to this take: 🧠📈 🧪

Exciting new findings in Computational Psychiatry? Only few more days to submit your late breaking abstract! 👇🏼 And don't forget to book your hotel - the conference's contingencies for hotel rooms are running low...

My PI is hiring a new postdoc! if you are interested in memory, navigation, or just curious about the hippocampus, come join a lab processing data from human single cell recordings up to whole brain MEG! (Deadline 28th May) www.ucl.ac.uk/work-at-ucl/...

My colleague Dan Bush (not on BSky) at UCL is looking for a post-doc. Focus on intracranial EEG and single cell recordings from epilepsy patients + MEG recordings from healthy volunteers during spatial and episodic memory tasks. Apply here tinyurl.com/n6nkty8e

Even honest conservatives can condemn starvation of a civilian population. And the far-more-intensive-than-ever bombing of civilians. Complete siege 8 wks+, food warehouses empty. So why is there such silence? This should be the headline every day. www.theamericanconservative.com/the-starvati...

Late Abstract Submissions Now Open – Limited Space Available! We are now accepting late abstract submissions for the 2025 Computational Psychiatry Conference in Tübingen! cmt3.research.microsoft.com/CPConf2025/S... (1/3) #CPConf2025

It’s a real shame that folks with mental illness have to fight not only their symptoms but also concerted efforts to undermine their treatment. 😢 The @nytimes.com mag published a long piece entitled “rethinking adhd”. Here is a 🧵 highlighting its factual & logical errors 1/n

Is it possible to estimate the neural response from fMRI BOLD? Lots of proposals (blind deconvolution, etc) but is it reliable enough? Looking for scenarios that are not just simple tasks. I'm guessing no but maybe regularization can help. What do the experts say? @danielemarinazzo.bsky.social

OK here it is, the moment you have all been waiting for! Our advert for 5 posts here at Glasgow: Cognitive neuroscience/psychology. Closing date May 12 - please spread the word www.nature.com/naturecareer...

LAST DAYS for EARLY BIRD registration which ends tomorrow... please register if you'd like to come to the Comp Psych conference this summer!

Come join our team! Super exciting project…

Hello world! We are building *personalized* feeds to help you make sense of research discussions on BlueSky! Pin our first feed below, which shows posts about papers from accounts you follow! Follow this account for more updates! bsky.app/profile/pape...

This is fascinating @philcorlett.bsky.social - like an inverse Capgras syndrome (emotion but no face!)…

Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness academic.oup.com/brain/articl...

❗RESEARCH OPPORTUNITIES❗ We're hiring for an ambitious @wellcometrust.bsky.social project exploring brain mechanisms of planning/inference in psychosis 🧠 Tackled at multiple scales: from single neurons to human behaviour/fMRI and neural networks. Opportunities for 1 post-doc 1 clinical fellow 👀

this is super interesting... nice work!

Submit an abstract for #Valentine's! 💗💗💗 Two more days to submit your abstract for the Computational Psychiatry Conference! #CPConf2025

🚨New postdoc job alert!🚨 www.ucl.ac.uk/work-at-ucl/... ...we are looking for someone with an interest in computational psychiatry and/or naturalistic neuroimaging to work on a new ERC Advanced grant "The Neurocomputational Mechanisms of Anxiety Treatment Response (MECHANX)". (1/3)

We are very excited to announce the open release of a new 170 participant dataset: Linked MEG, TMS, multimodal 3T MRI, 7T MRI, Connectom MRI, cognitive /questionnaire data. Immense effort from a fabulous CUBRIC team. Paper by Carolyn McNabb et al: doi.org/10.1038/s415...

v exciting job!