Brain network responsible for Parkinson’s disease identified

Scientists just discovered a key brain network affected by Parkinson’s disease. The finding could change how doctors understand symptoms and lead to better treatments. 🧠 bit.ly/4qdpLMf

A new study suggests Parkinson’s may stem from disruptions in a little-known brain network, reshaping how doctors think about the disease. trib.al/XFtsWKn

I’m very excited about this new work describing the specific cortical-striatal circuits that are altered in Parkinson’s Disease and that should be targeted for optimal PD treatment. www.nature.com/articles/s41...

Thanks to @shawnballard.bsky.social for this terrific synopsis of our latest work in @cellpress.bsky.social. The details of how stimulant medications like Ritalin work inside the brain will surprise you! doi.org/10.1016/j.ce...

This is your brain on Ritalin. Got your attention? Stimulant medications like Ritalin (methylphenidate) do, but not in the way you might think. They don't act directly on the brain’s attention systems! Find out what's really happening in @cellpress.bsky.social. doi.org/10.1016/j.ce...

Check out some compelling and timely work by @nasiametoki.bsky.social on sex vs gender differences in the developing adolescent brain!

Ever wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications! doi.org/10.1038/s414...

Poor image quality introduces systematic bias into large neuroimaging datasets, new study of ABCD data shows. By Natalia Mesa www.thetransmitter.org/spectrum/poo...

Excited to see the latest paper from @bttyeo.bsky.social's lab finally published in Nature! Now I know the most economical way to spend my grant money on MRI! No surprise, sample size matters, but adequate sampling in scan time can reduce the cost of sampling adequate numbers of participants.

Once again, if you give @gordonneuro.bsky.social et al a network, they're going to want to characterize its subnetworks... A thought provoking read on the AMN (née CON) and the brain architecture of the decision-action-feedback loop. I always feel smarter after reading these kinds of papers!

Fantastic work from @drdamienfair.bsky.social's using the latest in precision neuroimaging and neuromodulation to untangle the mechanisms of chronic pain!

It's not surprising to see that cutting off funding disrupts science and impacts its novelty, but I think it's important that this is documented and shared 🧪 . For more see the news coverage in @nature.com www.nature.com/articles/d41...

My med school textbook says stimulants like Ritalin treat hyperactivity by “stimulating” the brain’s attention and cognitive control systems. We studied children taking stimulants in the ABCD Study, and the largest differences were actually in arousal and reward networks! Check out our preprint!

Had a great time speaking with Sydney about our most recent paper out now in @natcomms.nature.com @macwoodburn.bsky.social . Paper link here: rdcu.be/ehbOy

The brainstem’s red nucleus is an evolutionarily old structure that emerged as animals began to use limbs for walking, but its function in humans reaches beyond motor control, a new study suggests. By @sydneywyatt.bsky.social #neuroskyence www.thetransmitter.org/brain-imagin...

It turns out the brain🧠is silently🤫working when your arm is in a cast. 🩼 🚧 Plastic changes occur, and revert again when the cast is removed … not just in cortex.

It's shocking how little is known about the brainstem red nucleus. In our new paper “The human brainstem’s red nucleus was upgraded to support goal-directed action” out now in @naturecomms.bsky.social we show that current thinking on the red nucleus is in need of a serious upgrade. rdcu.be/ehbOy

The brain’s action-mode network — a Perspective by Nico U. F. Dosenbach, Marcus E. Raichle & Evan M. Gordon @ndosenbach.bsky.social @gordonneuro.bsky.social www.nature.com/articles/s41...

The brain’s action-mode is created by a dedicated action-mode network (AMN) rdcu.be/d5odm. In the brain’s mode continuum, AMN sits opposite DMN’s default-mode, as yin-yang. AMN might be key in pain, apathy, Parkinson’s. New @natrevneurosci.bsky.social w/ Marc Raichle & @gordonneuro.bsky.social 🧵 ⬇️

Is it critical to stimulate @ndosenbach.bsky.social's SCAN and CON networks for clinical improvements of Tourette's patients that undergo DBS? Carlos Baldermann says yes in a cool new paper out in @natureportfolio.bsky.social comms today! www.nature.com/articles/s41...