Pumped to share our latest work! Here, we peeked under the hood of fMRI-based predictive models to ask whether models of sustained attention and autism symptoms rely on overlapping functional connections. www.medrxiv.org/content/10.6... 1/2

What matters most for childhood brain organization? We analyzed 649 variables. The answer: Socioeconomics (SES); with brain patterns pointing at sleep & stress as drivers. Even brain-IQ associations were better explained by SES. In Science today: www.science.org/doi/10.1126/...

New paper in Imaging Neuroscience by Andrew N. Van, Nico U.F. Dosenbach, et al: Frame-wise multi-echo distortion correction for superior functional MRI doi.org/10.1162/IMAG...

Excited to share our new preprint “Functional brain network correlates of pubertal timing and depressive symptoms in preadolescence” doi.org/10.64898/2026.05.22.727009 We examined how pubertal timing relates to whole-brain functional connectivity and depression risk in >9,000 youth (ABCD Study)

Get ready to get your mind blown! 🧠 ⛓️ Turns out cortex isn’t neatly following cytoarchitectonic borders, but more like a set of functional chains that link and split across regions, creating parallel processing streams. Safe to say this one might re-chain how we think about brain organization 👀

Don’t miss out reading about this amazing work linking the SCAN to Parkinson’s disease. What are the best ways we could use this new knowledge?!

Targeting the somato-cognitive action network (SCAN) rather than motor regions doubles efficacy of TMS treatments for Parkinson’s disease. Seems that various DBS targets for Parkinson’s are selectively connected to the SCAN rather than effector-specific motor regions.🧪 www.nature.com/articles/s41...

The highlight of my week was the publication of "Parkinson’s disease as a somato-cognitive action network disorder" in @nature.com. It's a great paper that shows how conceptual changes in fundamental neuroscience - the discovery of SCAN - can improve treatment 🧪 www.nature.com/articles/s41...

An “extraordinary” brain network discovery shows that Parkinson’s disease may not be a movement disorder after all

Scientists just discovered a key brain network affected by Parkinson’s disease. The finding could change how doctors understand symptoms and lead to better treatments. 🧠 bit.ly/4qdpLMf

Do not miss this incredibly important finding about the SCAN and Parkinson’s disease.

Fantastic work showint how SCAN is related to Parkinson’s disease. Much promise for the future of battling the disease! www.nature.com/articles/s41...

What if we've misunderstood how ADHD stimulants work? WashU Medicine brain imaging and child neurology teams joined forces to uncover where in the brain these drugs act — knowledge that could improve how attention disorders are treated. medicine.washu.edu/news/stimula...

Amazing work by @benjaminkay.bsky.social and the @ndosenbach.bsky.social lab on the effect of stimulant medications on the brain! A must-read!

After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:

🎓 Congratulations Dr. Jin Yang! Jin successfully defended his PhD thesis, "The Development of Deep-Learning-Based Automatic Multi-Organ Segmentation Models from CT Images and their Clinical Evaluation", as part of the Imaging Science PhD Program at WashU!

Is resting-state functional connectivity (rsFC), cortical thickness (CT), or cortical volume more effective at capturing sex and gender differences in the brains of preadolescents? Check out our new article (doi.org/10.1016/j.dc...) now out in Developmental Cognitive Neuroscience.

Ever wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications! doi.org/10.1038/s414...

My med school textbook says stimulants like Ritalin treat hyperactivity by “stimulating” the brain’s attention and cognitive control systems. We studied children taking stimulants in the ABCD Study, and the largest differences were actually in arousal and reward networks! Check out our preprint!

The brainstem’s red nucleus is an evolutionarily old structure that emerged as animals began to use limbs for walking, but its function in humans reaches beyond motor control, a new study suggests. By @sydneywyatt.bsky.social #neuroskyence www.thetransmitter.org/brain-imagin...

Had a great time speaking with Sydney about our most recent paper out now in @natcomms.nature.com @macwoodburn.bsky.social . Paper link here: rdcu.be/ehbOy

It turns out the brain🧠is silently🤫working when your arm is in a cast. 🩼 🚧 Plastic changes occur, and revert again when the cast is removed … not just in cortex.

It's shocking how little is known about the brainstem red nucleus. In our new paper “The human brainstem’s red nucleus was upgraded to support goal-directed action” out now in @naturecomms.bsky.social we show that current thinking on the red nucleus is in need of a serious upgrade. rdcu.be/ehbOy

Happening now! Don’t miss out - Come find me at Poster Session E (#E127) at #CNS2025 to discuss how brain functional connectivity, but not neuroanatomy, captures the interrelationship between sex and gender in preadolescents. @cnsmtg.bsky.social

At #CNS2025? Come visit my poster (#E127) Mon afternoon (2:30-4:30pm) to learn how brain functional connectivity, but not neuroanatomy, captures the interrelationship between sex and gender in preadolescents @cnsmtg.bsky.social @ndosenbach.bsky.social Preprint here: www.biorxiv.org/content/10.1...

Amazing work by Dr. Yin Wang, Jamie Reilly, Haroon Popal, and others. The scale of this work is breathtaking.

Why do we not remember being a baby? One idea is that the hippocampus, which is essential for episodic memory in adults, is too immature to form individual memories in infancy. We tested this using awake infant fMRI, new in @science.org #ScienceResearch www.science.org/doi/10.1126/...

A French University is funding a Safe Place For Science program meant to recruit scientists who cannot continue their work in the US. www.univ-amu.fr/fr/public/a...

Vote for WashU Medicine in #STATMadness! Help a publication from Nico Dosenbach, MD, PhD, & colleagues on the effects of psilocybin on the brain make it to the finals! Round 1 ends March 10 at 3 a.m. CT. Read the article: www.statnews.com/wp-content/u... Vote! www.statnews.com/feature/stat...

WHERE WILL YOU BE ON MARCH 7TH!? Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one! #standupforscience2025

The brain’s action-mode network — a Perspective by Nico U. F. Dosenbach, Marcus E. Raichle & Evan M. Gordon @ndosenbach.bsky.social @gordonneuro.bsky.social www.nature.com/articles/s41...

The brain’s action-mode is created by a dedicated action-mode network (AMN) rdcu.be/d5odm. In the brain’s mode continuum, AMN sits opposite DMN’s default-mode, as yin-yang. AMN might be key in pain, apathy, Parkinson’s. New @natrevneurosci.bsky.social w/ Marc Raichle & @gordonneuro.bsky.social 🧵 ⬇️

Is it critical to stimulate @ndosenbach.bsky.social's SCAN and CON networks for clinical improvements of Tourette's patients that undergo DBS? Carlos Baldermann says yes in a cool new paper out in @natureportfolio.bsky.social comms today! www.nature.com/articles/s41...

New paper out today in PNAS 🎉 demonstrating: 1) an association between social disadvantage & child brain function can be observed as early as birth 2) these alterations are brain-wide, but most pronounced in functional networks & subcortex later linked to childhood adversity doi.org/10.1073/pnas...