Sam Krimmel
@samkrimmelneuro.bsky.social
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Neuroscientist post-doc working with Nico Dosenbach at Washington University in St. Louis
reposted by
Sam Krimmel
Cell - a Cell Press journal
about 2 months ago
as well as research articles on how stimulant medications affect arousal and reward rather than attention networks
www.cell.com/cell/fulltex...
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Stimulant medications affect arousal and reward, not attention networks
Stimulant medications (e.g., methylphenidate) were thought to improve attention by acting on the brain's attention networks. Functional connectivity data now reveal that stimulants are associated with...
https://www.cell.com/cell/fulltext/S0092-8674(25)01373-X
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reposted by
Sam Krimmel
Jianxun Ren
12 days ago
It’s time to rethink Parkinson’s disease. Our work reframes PD as a disorder of the somato-cognitive action network (SCAN), and shows that normalizing SCAN connectivity represents a shared mechanism across diverse effective therapies.
rdcu.be/e2n4t
@ndosenbach.bsky.social
@gordonneuro.bsky.social
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reposted by
Sam Krimmel
Springer Nature
13 days ago
A recently discovered brain network that links cognition (thinking) and actions may have an important role in Parkinson’s disease and could improve its treatment, according to a study published in Nature:
spklr.io/63320DMwOi
#Neuroscience
#Neuroskyence
#Parkinsons
đź§ đź§Ş
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Parkinson’s disease as a somato-cognitive action network disorder - Nature
The substantia nigra and all Parkinson’s disease deep-brain stimulation targets are selectively connected to the somato-cognitive action network rather than to effector-specific motor regions.
http://spklr.io/63320DMwOi
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reposted by
Sam Krimmel
Scientific American
13 days ago
An “extraordinary” brain network discovery shows that Parkinson’s disease may not be a movement disorder after all
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Scientists discover brain network that may cause Parkinson’s disease
An “extraordinary” brain network discovery shows that Parkinson’s disease may not be a movement disorder after all
https://www.scientificamerican.com/article/extraordinary-brain-network-discovery-changes-our-understanding-of/
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reposted by
Sam Krimmel
Jianxun Ren
12 days ago
Non-invasive brain surface stimulation targeting personalized SCAN alleviated symptoms in patients with Parkinson’s disease. See the videos below.(
www.nature.com/articles/s41...
)
add a skeleton here at some point
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reposted by
Sam Krimmel
Jianxun Ren
12 days ago
Happy to share a short but super cool video that gives a quick overview of our Nature paper on the somato-cognitive action of netwokr in Parkinson's disease
www.nature.com/articles/s41...
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reposted by
Sam Krimmel
Evan Gordon
12 days ago
I’m very excited about this new work describing the specific cortical-striatal circuits that are altered in Parkinson’s Disease and that should be targeted for optimal PD treatment.
www.nature.com/articles/s41...
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incredible and exciting work
add a skeleton here at some point
11 days ago
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reposted by
Sam Krimmel
Benjamin Kay
9 months ago
My med school textbook says stimulants like Ritalin treat hyperactivity by “stimulating” the brain’s attention and cognitive control systems. We studied children taking stimulants in the ABCD Study, and the largest differences were actually in arousal and reward networks! Check out our
preprint
!
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Had a great time speaking with Sydney about our most recent paper out now in
@natcomms.nature.com
@macwoodburn.bsky.social
. Paper link here:
rdcu.be/ehbOy
add a skeleton here at some point
9 months ago
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It's shocking how little is known about the brainstem red nucleus. In our new paper “The human brainstem’s red nucleus was upgraded to support goal-directed action” out now in
@naturecomms.bsky.social
we show that current thinking on the red nucleus is in need of a serious upgrade.
rdcu.be/ehbOy
10 months ago
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