Huge congrats to my grad student, Dr. Anna Rader Groves, who successfully defended her disseratation last week! I consider myself lucky to have mentored Anna over the past 5 years.

Excited to share our preprint! Impressive effort from grad student Anna Rader Groves and co-author @cgalli-io.bsky.social, in collaboration with Melanie Grubisha and Robert Sweet (PITT). @grubisha

Excited to share our preprint! We show that primary visual cortex is modulated by global predictability. This effect depended on higher level brain region (area ACa), and better explained classic oddball paradigms better than “local” context effects (i.e., recent stimulus history). 1/3

Our new preprint is out! We show that deviance detection in auditory cortex conveys the theorised comparison of internal prediction to sensory input. Our data confirm this key assumtion that links theoretical models of sensory processing to experimental data. www.biorxiv.org/content/10.6...

FYI…New York announced $10M in state funds for brain research. #neuroskyence #PsychSciSky www.governor.ny.gov/news/governo...

Visuomotor mismatch EEG responses in occipital cortex of freely moving human subjects https://www.biorxiv.org/content/10.1101/2025.08.14.670295v1

Just learned that my @acnporg.bsky.social panel was accepted! With my colleagues Zoë Hughes, @jordanhamm.bsky.social, Bryan Baxter & Patricio O'Donnell, our #ACNP2026 panel will highlight cross-species approaches using functional brain-based biomarkers to address translational gaps in psychiatry

First lab outing since the move to NYC.... feeling so lucky to have such a talented and fun group! with Lital Rachmany, @adhockley.bsky.social, me, Molly Hornick, Fumiyasu Imai, and @cgalli-io.bsky.social

I’m delighted to congratulate Dr. Connor Gallimore for successfully defending his dissertation, “Patterns of laminar engagement during visual mismatch processing”. I consider myself lucky that Connor joined my lab in 2019. His CV, though impressive on its own, doesn’t even scratch the surface.

Beautiful views and stimulating science discussion this week at University of Zurich/ETH Zurich with Wolfger von der Berhens, Fatih Yanık and many others. Honored to share my work with such a world class group!

There are many studies on cell types and then there is the gold standard. Beautiful work on the diversity of VIP interneurons by the Rudy lab! #neuroskyence www.biorxiv.org/content/10.1...

I'm hiring a full-time research technician to work in my lab at Nathan Kline. Benefits included! Some lab experience preferred... experience with mouse surgeries a huge plus. If you live in NYC, there are two daily shuttles that take ≈20 min from upper manhattan. nki.applicantpro.com/jobs/3663631

New results from study of cortical thickness in 1211 psychosis cases and 734 controls demonstrates that "visual cortex is among the most profoundly affected brain regions", with effect sizes larger than prefrontal regions. www.medrxiv.org/content/10.1...

Press release of our new article in Neuron: How Does the Brain Differentiate New Stimuli From Old Ones? | Columbia News news.columbia.edu/news/how-doe...

Our new paper is out in Neuron! We characterize auditory prediction errors across primary and secondary regions, to simple and complex stimuli. Deviance detection (and context) are distinct from basic adaptation -- even in a simple oddball paradigm. 1/2 www.sciencedirect.com/science/arti...

Comment on our recent paper challenging the link between MMN dysfunction and positive symptoms: www.sciencedirect.com/science/arti... Thanks @mattnour.bsky.social I may have missed it but cognitive map dysfunction is also unrelated to positive symptoms so far?

www.nature.com/articles/s41... Lots to unpack in this Nat Neuro paper on schiz genetics (ctx-wide GABA, amygdala, no DA?) One thing: in terms of exc neurons, a vis-ctx specific cluster (133) and a ctx-wide cluster (123) is as implicated (if not, more) than the most prominent PFC cluster (404).

One of the disappointing trends for urban college neighborhoods over the last few years is the introduction and maintenance of restrictions on access in and thru formerly open walkways. So it's great to see efforts to protect these public easements. www.nydailynews.com/2025/01/15/a...

New lab preprint ! There is a lot of excitement about the therapeutic potential of psilocybin but what is the mechanism? A beautiful body of work from @alexkwan.bsky.social shows that PFC plasticity is important. But how does this unfold and in which cell types? www.biorxiv.org/content/10.1...

Individuals with psychosis struggle with visual pattern integration, linked to altered brain activity and weakened connectivity in key visual areas, particularly during tasks involving background noise #Psychosis #MentalHealth #VisualPerception #Neuroscience #BrainConnectivity

We're all parts of institutions, and we're all vexed by seemingly pointless obstacles and bureaucracy at one point. Chesterton's fence provides a great lesson -- "Do not remove a fence until you know why it was constructed in the first place" #neuroskyence fs.blog/chestertons-...

Nature Neuroscience is hiring a computational/systems/cognitive editor! Come join our team! Happy to answer any questions. springernature.wd3.myworkdayjobs.com/SpringerNatu...

Here is a somber truth of creative life. If it goes well, people will begin to ask you for things. Each of those things, no matter how kind or flattering or genuine or even beneficial to your own career and finances as well as someone else's, will pull you from your true purpose.

Our book chapter is out! Written for clinical researchers interested in translating neurophysiological biomarkers to rodent models doi.org/10.1007/978-...

Our spotlight article in Trends in Neurosciences is out! We contextualize the recent findings by Furutachi, Hofer et al in the broader literature on V1 deviance detection and prediction error www.sciencedirect.com/science/arti...