Early unilateral auditory deprivation can cause lasting spatial #hearing deficits. @anbuhlk.bsky.social &co show that unilateral #HearingLoss during development (but not adult-onset) impairs binaural #brainstem function & spatial hearing acuity in guinea pigs @plosbiology.org 🧪 plos.io/46njw1P

Sad day for peope who still believe brain areas are the primary organizational units of function in the brain. www.nature.com/articles/s41...

music lessons don't make kids smarter, but many people have assumed that music lessons would have near-transfer effects, e.g. improving aspects of auditory perception big new study led by Andrew Oxenham says "nope". music lessons make kids better at music & that's good enough reason to do 'em !

First lab outing since the move to NYC.... feeling so lucky to have such a talented and fun group! with Lital Rachmany, @adhockley.bsky.social, me, Molly Hornick, Fumiyasu Imai, and @cgalli-io.bsky.social

Are predictions computed hierarchically, or can they be computed locally? Check out our paper! Congrats, Toshitake Asabuki and @colleenjg.bsky.social ! www.pnas.org/doi/10.1073/...

#ICYMI Areas of the brain that help a person differentiate between what is real and what is imaginary have been uncovered in a new study led by @uclpals.bsky.social‬ and @uclqsion.bsky.social‬ researchers.

📣New study in Neuron, featuring modeling insights: "Cell-Specific Dendritic Integration in Cortical GABAergic Interneurons"! It reveals PV & SST interneurons compute differently. This highlights how distinct dendrites enable specialized brain computations! www.sciencedirect.com/science/arti...

Here's our new #preprint on triggering of cortical Up states by deviants in the auditory oddball paradigm. Up states are reliably evoked by deviants under anesthesia, explaining the long-latency deviant responses seen in previous studies. www.biorxiv.org/content/10.1...

🚀 We are excited to share that bombcell is now available in Python! 🐍 Automatically sort your units into good/MUA/noise/non-somatic using quality metrics and interpretable & adjustable classification thresholds. pip install and play around with our toy dataset: 🔗 github.com/Julie-Fabre/...

A great catch up today in the Jono's @ Nottingham 🏰

My final day at the @incyl.bsky.social today! I've met so many amazing people here and I'll miss everyone so much 🩵 next step is back to UK for a month of hiking, cycling and camping, then heading to @jordanhamm.bsky.social lab soon! 🗽

Excited to share my PhD paper! In it, we use targeted 2-photon optogenetic stimulation to determine how V1 activity is read-out in a detection task. We found that network influence, not visual coding properties, predicted the impact of ensembles on behavior - contradicting our expectations (1/5).

1/ Excited to share our new paper just out in Scientific Reports! 🧠🎧 Using intracranial EEG, we show how the human brain automatically encodes patterns in random sounds– without attention or explicit awareness. 🔗 doi.org/10.1038/s415...

Exciting work showing an objective test for tinnitus! www.science.org/doi/10.1126/...

How does our brain predict the future? Our review of predictive processing + research program is now on arXiv arxiv.org/abs/2504.09614 50+ neuroscientists distributed across the world worked together to create this unique community project.

Does your research involve comparing experimental conditions? Then our latest publication is for you: We developed generalized contrastive PCA (gcPCA), a tool for comparing high-dimensional datasets. 🧠📊 doi.org/10.1371/journal.pcbi.1012747 This tool was born out of necessity, here is the story. 🧵 1/

New preprint with systematic measurements of feature tuning in the mouse auditory system made with robust representation similarity analysis. Validates a range of earlier observations and generalizes beyond that. www.biorxiv.org/content/10.1...

Thrilled to present our paper out today in @cp-cellreports.bsky.social We asked how prediction errors are generated in the auditory cortex during the oddball paradigm. When blocking top-down prediction signals from mPFC, we saw reduced prediction errors in A1. doi.org/10.1016/j.ce...

Excited to share my latest work just out in @pnas.org! This NIH MOSAIC K99-funded project identifies a top-down cortical circuit—from cingulate to auditory cortex—that supports auditory perceptual performance in challenging listening conditions: www.pnas.org/doi/10.1073/...

Some really nice work on autonomic prediction errors in cortical circuits