Excited to share our latest paper in which we discuss merging theory-and data- driven computational psychiatry in a large transdiagnostic cohort study (N=2400) www.biologicalpsychiatrycnni.org/article/S245... Christopher Pittenger, Godfrey Pearlson @annierhcheng.bsky.social @sobp-org.bsky.social

If you live in the UK, please consider filling this in to keep the BBC reporting truth in our world of lies: www.gov.uk/government/c.... And here are some suggestions regarding answers: britishbroadcastingchallenge.com/wp-content/u...

Come work with us! really great team and super exciting project.

The really exciting moments. Many congratulations Dr Chen! @jiazchen.bsky.social

Postdoctoral research position in #ComputationalPsychiatry and #EEG as part of relmed.ac.uk trial testing reinforcement learning as biomarker for antidepressant treatment response. www.ucl.ac.uk/work-at-ucl/... @uclbrainscience.bsky.social @mikebrowning.bsky.social @relmed.bsky.social

📣🔥Thrilled to announce that 2026 Computational Psychiatry Conference will take place in New Haven, CT, btw July 14-16 - www.cpconf.org @robbrutledge.bsky.social @drrickadams.bsky.social @tobiasuhauser.bsky.social @docqhuys.bsky.social @clairegillan.bsky.social Sonia Bishop More info to come soon!

vimeo.com/1125505169?f... Are you: ✅ Aged 18 or over ✅ Experiencing depression or low mood ✅ Registered with a GP in England You may be eligible to take part in the RELMED Study, exploring ways to improve treatment for depression. 🎥 Watch our short introductory video to learn more!

New #neurojob #psychiatryjob #jobalert. www.northlondonmentalhealth.nhs.uk/current-vaca.... Focus is on clinical trials for mood disorders, with close links to @uclpsychiatry.bsky.social @uclqsion.bsky.social and @mpc-comppsych.bsky.social

In a Comment, @docqhuys.bsky.social and Michael Browning argue that the field of computational psychiatry will improve patient outcomes through its increasing focus on interventions and trials. #mentalhealthresearch #Psychiatry ➡️ nature.com/articles/s43... 🔓 rdcu.be/eKp1v 🧵(3/8)

Depression can affect the mind, body and daily life in ways you might not expect. 🧠Swipe to learn the key signs and symptoms – and why recognising them matters. #Depression #Mentalhealth #Research

Curious about how scientists measure brain activity through EEG? Swipe to read more! ⚡️

🧠🌍 On World Mental Health Day, we’re reminded that mental health is a global priority. RELMED is committed to developing evidence-based practices to improve how we treat depression. Thank you to all our participants and everyone who has contributed to research. Each voice truly makes a difference.

New #job alert! Clinical research fellow / postdoc in #computationalpsychiatry at the @mpc-comppsych.bsky.social / @uclqsion.bsky.social and UCL psychiatry. We will aim to understand the computations engaged by serotonin in the treatment of depression. Please re-sky. www.ucl.ac.uk/work-at-ucl/...

Proud husband! Ivana Gavric's new single is out m.youtube.com/watch?v=OegD...

🧠 We're hiring a computational postdoc! 3+ years with me & @mitulamehta.bsky.social on @wellcometrust.bsky.social funded social cognition/paranoia research at the IoPPN. Lead & develop computational work, collaborate with experimentalists on psychosis/THC data. DM for details! lnkd.in/eCMy9Jf5

The brain's priors have been found! They were hiding everywhere: www.nature.com/articles/s41.... So if this is true for "simple" decisions, it should also be true for more complex ones, like, say, emotions, right?

🧵 New paper! We studied depression symptoms and goal-directed decisions under uncertainty @shiyiliang.bsky.social, with @evanrussek.bsky.social & @robbrutledge.bsky.social Surprisingly, we found that apathy–anhedonia was linked to enhanced goal-directed behavior. www.biorxiv.org/content/10.1...

… Link here: www.biorxiv.org/cgi/content/... ... (2/15)

📢 We are hiring! 📢 For our @wellcometrust.bsky.social grant on information gathering biases in #OCD and #Schizophrenia, we are looking for a Postdoc in Computational Modelling, supervised by Peter Dayan and myself. Interested? See all the details in the job advert here: devcompsy.org/wp-content/u...

Another exciting new job opening at @uclpals.bsky.social with Niko Steinbeis and Essi Viding - www.ucl.ac.uk/work-at-ucl/... #neurojob #computationalpsychiatry

Still open!

🚨 We’re hiring: Associate Professor/Professor of Cognitive Neuroscience 🧠 Lead pioneering imaging-informed cognitive neuroscience research 🌍 Open to international applicants | Visa sponsorship available 📍 Permanent, full-time, on-site 🔗 Apply now: www.ucl.ac.uk/work-at-ucl/...

#neurojob #psychiatry @rcpsych.bsky.social @uclqsion.bsky.social @relmed.bsky.social

New position alert! This is an exciting position for a Specialty Doctor to take a leading role in developing the North London Mood Disorders Research Clinic in a national network of Mental Health Mission research clinics apps.trac.jobs/job-advert/7.... @noclor.bsky.social @uclpsychiatry.bsky.social

I still get chills Meet Mike *30+ years severe depression *first hospitalized @ 13y *20 meds *3 rounds of ECT *2 near-fatal suicide attempts Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE see videos, read paper, follow thread doi.org/10.31234/osf...

Associate Professor/Professor of Cognitive Neuroscience job opening in our own @imagingneuroucl.bsky.social department. Details here: www.ucl.ac.uk/work-at-ucl/...

Here we go. #cpconf2025 is over. Thank you all for a superb conference and in particular @tobiasuhauser.bsky.social and Susan Fischer!

Introducing our fantastic RELMED Team! 🧠 [Part 1] @docqhuys.bsky.social @nikkisingh.bsky.social

The bar is high!

@roelandheerema.bsky.social at #cpconf2025 talking about a new task linking specific emotional appraisals to computational states.

Jiazhou Chen at #cpconf2025 on generalisation of MEG signatures of emotional states.

The RELMED team @docqhuys.bsky.social @hylu.bsky.social @muzhiwang.bsky.social is presenting our study at #CPC2025 in Tübingen, Germany this week! Come find us at Poster Session 3 on Wednesday 16th July at poster number 3.24 and 3.26!

Can we quantify mental states using LLMs? What are the limits? When does it and when does it not work and why? Jakub Onysk talking #cpconf2025

Since Davies & Read review of 2019 Sameer Jauhar and I have been trying to get closer to the truth about AD discontinuation. It’s entered guidelines as FACT: 50% will experience difficulty stopping. So we completed the DEFINITITIVE meta-analysis of trial data. jamanetwork.com/journals/jam...

V important meta-analysis doi.org/10.1001/jama...: Discontinuation symptoms 1 week post stopping antidepressants was below the threshold for clinically significant discontinuation syndrome. Later worse mood is likely depression relapse @jfhayes.bsky.social @sameerjauhar.bsky.social.

Come visit us at stall 48 to learn more about RELMED and get a personally drawn postcard from our friendly lab robotic arm 🤖🦾

Deadline today - looking forward to the applications!

@yanivabir.bsky.social and Zeguo Qiu are presenting exciting new behav & eeg battery of reinforcement learning tasks developed to see if different rl processes are selectively engaged by DA and 5HT. #BAP2025 @bapsych.bsky.social

"substantially" is notable given this is in people with treatment-resistant depression, i.e. when there is a depression that has not responded to at least two other antidepressants.

@mikebrowning.bsky.social‬'s paper on pramipexole in treatment-resistant depression is now out - very encouraging results authors.elsevier.com/sd/article/S....

Early registration is OPEN for the next #BrainConference! 🧠 🇬🇷 For the first time ever, the Brain Conference is heading to Fodele Beach in Crete, Greece, and you’re invited! 🌟 Register by 10 July 2025 👉 https://loom.ly/ei_yabg#BrainConference! @lundbeckfonden.bsky.social @brainprize.org

Thank you @santhouse.bsky.social for this exploration of the blurry line between healthy and ill, of how cultural norms affect our views of who is ill. It highlights challenges when we get this wrong - like raising awareness without having sufficient answers. A very curageous and necessary book!

Delighted to announce this position www.northlondonmentalhealth.nhs.uk/current-vaca.... It's part of the Mental Health Mission Mood Disorders Research Clinic Network, aiming to support clinical trials in mood disorders in the UK. Should be very interesting! oxfordhealthbrc.nihr.ac.uk/mhm/mood-dis...

Super to see this out! Pavlovian biases have shown predictive power a surprising range of settings, e.g. long-term course of alcohol use. Here, we find that Pavlovian biases are engaged by therapy; and that this engagement medicates outcomes in NHS setting. Congratulations @liobanause.bsky.social!

NEW DEADLINE: Friday 20th June 🚨 MEG‑UKI 2025 lands in London (16–18 July)! A 3-day deep dive into the brain—naturalistic neuroscience, OP-MEG, cutting-edge methods, and real-world impact. Keynotes by Dominik Bach & Jamie Ward. Art, abstracts, and more! Register here: meguk.ac.uk/registration/

This was hard work, but ultimately there is support in the literature that engagement of different RL processes by serotonergic and dopaminergic/noradrenergic pharmacological interventions may be a promising route to follow. The @relmed.bsky.social study will do just that.

Same for peer review methinks - let's not throw the baby out with the bathwater. www.science.org/content/arti...

We are delighted to announce that the 2025 UCL Neuroscience Symposium is now sold out! The symposium is UCL's flagship cross-faculty neuroscience event with hundreds of neuroscientists expected to attend. We look forward to seeing all those who registered next Wednesday!

RELMED.ac.uk is now open to recruitment. This @wellcometrust.bsky.social-funded study wellcome.org/research-fun... will ask whether reinforcement learning tasks are differentially sensitive to dopaminergic and serotonergic antidepressants.

Thank you @clairelavalley.bsky.social and @rssmith.bsky.social. Striking to see aversive pruning altered in people with methamphetamine use, particularly given the results in depression (dx.doi.org/10.1017/S003...).