We have a ✨NEW PREPRINT✨! Using data from the @clscohorts.bsky.social Millennium Cohort Study and linked healthcare records, we tested the association between social media use and psychiatric diagnoses in secondary care in young people in England. This is still a work in progress - feedback welcome!

Since Davies & Read review of 2019 Sameer Jauhar and I have been trying to get closer to the truth about AD discontinuation. It’s entered guidelines as FACT: 50% will experience difficulty stopping. So we completed the DEFINITITIVE meta-analysis of trial data. jamanetwork.com/journals/jam...

The association between gabapentinoids and risk of self-harm is multifaceted: These findings do not support a direct effect of gabapentinoid treatment on self-harm but underscore the necessity for close patient monitoring throughout the gabapentinoid treatment journey www.bmj.com/content/389/...

Thanks for your interest in our study. I agree with your summary and the issues raised.

Metformin is recommended for antipsychotic associated weight gain. However, in >25k patients initiating antipsychotics, only 3.3% received metformin in the first 2 years. In this small group, it seems to work: patients lost 0.65% of their body weight vs. gaining 4.16% on antipsychotics alone.

FDA removes risk evaluation and mitigation for clozapine, including neutrophil monitoring www.fda.gov/drugs/postma...

It’s generally agreed that aripiprazole conveys less cardiometabolic risk than the other, commonly prescribed, second gen antipsychotics, but that it’s potentially less effective. But there is a lack of evidence for this position.

New #datamind paper: physical health screening in people with severe mental illness in the UK is insufficient. Until it improves, it seems hard to see how we will move the needle on premature mortality in this population

“Unease”

Unfortunately a nuanced story is far less compelling than pitching this as a simple “good vs evil”.

New (expensive) drugs don’t gain QALYs www.thelancet.com/journals/lan...

In the UK, 80% of antipsychotic prescribing is for one of 4 drugs: olanzapine, quetiapine, risperidone or aripiprazole

I stand by everything I've ever said on Twitter, so I've put it all here. Lets see how it fairs, shorn of any context. New material coming soon.

Is @altmetric a good enough reason to stay on X?

Like data science and health informatics for mental health? Come and work with us:

DOI: 10.4088/JCP.13m08978 and DOI: 10.4088/JCP.11m06831 #ICanHazPDF

There’s a reason behind every sign… #most #british #sign #ever

.@TheLancetPsych This: appears to be a Chat-GPT copy of of our 2019 article:

Basically, everything needs to be improved to retain doctors in the UK.

Low Traffic Neighbourhoods deliver significant health benefits

Just received a great email auto reply that was essentially “I’m currently very busy doing my job, so I can’t get back to you” and I have found my new motto!

Brief comment from me in Science about a new paper showing the association between air pollution and suicide in China

Strange bedfellows. The anti-psychiatry crew always get so upset when it’s suggested they are furthering a right wing agenda.

Happy birthday @Kurt_Vonnegut (yesterday)

Happy birthday @Kurt_Vonnegut

#GPT4 #LLM highlight negative bias to psychiatry in major journals

Things I didn’t know about my inspiring colleague @Naaheed_Mukadam @UCLPsychiatry

New academic life hack: switch on Out of Office 2 days before leave starts. Those unlucky people emailing just before holiday are almost certain to never receive a reply. You are welcome.

Huh?

Really happy to have completed two randomised controlled trials of @juli_health see here: improves asthma and depression. Preprints are available, but awaiting peer-reviewed publications

Harry Kane’s last penalty for Spurs 😢 #kane #thfc

Outrage drives engagement on Twitter. It’s just a huge multiplayer video game that rewards the angry.

Just a nice/normal day on Twitter

at first mental health contact people with lower incomes were more likely to have more severe symptoms and then receive less treatment time

Regions of Sweden with higher clozapine, lithium and ECT use have lower rates of male adolescent suicide highly unlikely to be causal (ecological fallacy etc) - perhaps regions with more use of these have better/more comprehensive MH services in general.

Ok. Ok. Ok

Responding to #reviewer2? Be more Wittgenstein

Thanks to all my mentors, colleagues, collaborators, students, funders, referees. From October, just call me Professor Hayes 😁

Critical/anti/whatever-psychiatry exists in a post-truth world enabled by popularists. There is considerable overlap with anti-vax, anti-science thinking. Science rarely deals with certainties this should be a 🚩 re: antidepressants

A fantastic colleague!

Signal in the noise

Can someone who is a psychiatry trainee run an NHS clinic?

#serotonin #antidepressants

Serotonin umbrella review should be retracted. JM is but one voice in UCL, where academic free speech is a key tenet. But the errors in her work are multiple and dangerous

#CleanAirDay out today: bipolar depression acutely impacted by air pollution

In advance of Mental Health Awareness week next week, I answered some questions about my work:

Premature mortality in severe mental illness it’s still getting worse, since we found this in 2000-2014 data.

Conflating opioid and antidepressant use is stigmatising and not based on evidence

from @NatalieShoham with @GemmaLewis13 @ClaudiaACooper1 & Steven Silverstein