🚨 New preprint alert! DNMT1 is often elevated in cancer, but its direct impact on DNA methylation regulation has been hard to isolate in tumours full of confounding processes. Using a clean genetic system in mESCs, we asked: What does excess DNMT1 by itself do to the methylome? Let’s dive in 🧵 1/9

New work from the lab by @eli-elder.bsky.social !! Tread to follow shortly...

The recruitment campaign is on! We’re seeking outstanding MSc, PhD, and Postdoctoral candidates to join @cra-chusj.bsky.social . If you’re passionate about epigenetics, development, and neurodevelopment, consider exploring the opportunities available in my lab. event.fourwaves.com/campagnerecr...

My Canadian university, Queen's, is offering TWENTY 4-year funded PhDs (40k CAD/yr) for a student of ANY citizenship who has been accepted at a top 100 US university but have had offer rescinded OR are reconsidering offer due to US policy. Details found here👇 www.queensu.ca/grad-postdoc...

EMBO is delighted to announce that this year the EMBO Gold Medal is awarded to Tanmay Bharat @tbharat-lab.bsky.social ‬ @mrclmb.bsky.social and David Bikard @dbikard.bsky.social @pasteur.fr for their remarkable contributions to the #LifeSciences. www.embo.org/press-releas... #award 🧪

Congrats to all winners! ...but especially to own, Michelle Robb, for the Best Poster Award at #DOHaDCanada2025! Michelle presented our recent advances on Early Embryonic Alcohol Exposure ! 🏆

Thank you, #DOHaDCanada2025, for organizing and for the invitation to present our work on Early Embryonic Prenatal Alcohol Exposure! #FASD #DOHaD #communautéFRQ

Congratulations to our co-president, Dr. Kristin Connor (@kconnor.bsky.social), for being awarded the Nick Hales Award by the International DOHaD Society. #DOHaD2025

Come join us at @mcgill.ca as an assistant professor in virus-host interactions! Please share widely. mcgill.wd3.myworkdayjobs.com/en-US/McGill...

Paper Out👇🥳 thanks to ALL authors, Nakatani-san @tamas-schauer.bsky.social @palmrinmoy.bsky.social and bluesky-less RIF1 regulates Replication Timing in mouse embryos & (suprising) findings disentangling effects on transcription and LADs...lots to think about 🙄👍🤔 👉 www.cell.com/developmenta...

Sophie Petropoulos, chercheuse au CRCHUM, et son équipe révèlent pour la première fois que l’embryon préimplantatoire de cochon d’Inde est très similaire à l’embryon humain, ce qui ouvre la voie à une meilleure compréhension de l’infertilité et du développement humain précoce.

🥂Congratulations to Petropoulos & co for their new Open Access study in our journal (@naturecellbiology.bsky.social): single-cell #transcriptomics, spatial, functional and comparative analyses show that the guinea pig presents high similarity with early human #embryogenesis. bit.ly/3RaRwWY

The Lim Lab at the @crchum.bsky.social is recruiting PhD students or Postdoctoral Fellows to study the roles of 14-3-3zeta in #adipocytes or pancreatic #betacells. Projects are supported by CIHR, NSERC, or Diabetes Canada. Please share with people who might be interested! Thanks!

I urge folks to sign this letter and share it with their university colleagues to get critical mass.

🔊Share widely! Were looking for a Tier 2 CRC in Human Metabolic Disease! Just posted but hurry as app deadline is May 15! Got expertise in #obesity or #diabetes and are an emerging expert in your field? Apply now!!!! carleton.ca/deputyprovos...

Dear USA colleagues, paradoxically the environment is warmer for doing science north of the border.♥️

This should save grant reviewers a lot of time on some of those proposals…..

Argonautes 2025 will cover progress in: Structural insights Effector complexes: formation, composition & function Post-transcriptional silencing Transcriptional silencing & DNA cleavage Post-translational modifications and regulations Medical aspects 27-30/8/2025 argonautes.img.cas.cz Pls RT!

For Canadian cancer researchers concerned about travelling to the US (🙋🏼‍♂️), please check out and plan to be at the Canadian Cancer Research Conference in Calgary this November. All welcome. www.ccra-acrc.ca/conference/

Thank you @stemcellnetwork.ca for internship scholarship to the lab to support the next generation of stem cell scientists!!

A few days left to apply for exciting PhD and Postdoc opportunities in wonderful Copenhagen and join our efforts in understanding Epigenetic Cell Memory.

Come by my colleague!! Assistant professor position in molecular neurobiology at @mcgill.ca and the Lady Davis Institute! mcgill.wd3.myworkdayjobs.com/McGill_Caree... Montreal is an amazing city and the Lady Davis is a great institute to work at!

🌟 SAVE THE DATE: Talent Forum 2025! 🗓️ November 18–19 📍 @www.helmholtz-munich.de‬, Germany Showcase your research and network with global talents in #Epigenetics & Nucleic Acids Research! Apply by July 31 for a speaker spot —travel & accommodation covered. 🔜 Website coming soon!

📣 Tenure track job alert! Assistant and associate tenure-track position at McGill University in toxicology and/or pharmacology. I know the department very well and could not speak more highly of the supportive environment it provides and of its leadership! www.nature.com/naturecareer...

Now seems like a great time to share a starter pack I made when I joined BlueSky! Let me know if you'd like to be added: go.bsky.app/6aMSMpy

Our next seminar is this Friday, March 21! This week, we welcome Drs. Cheryl Arrowsmith and Riley Horvath from @uoft.bsky.social where they will discuss pharmacological tools for manipulating the #epigenome. Register at: us06web.zoom.us/webinar/regi...

This. But also we are up against the fact that academic scientists in particular are often unprepared to think of ourselves as workers, build solidarity, and take collective action. This moment is going to require a really big pivot!

We are hiring our next Department Head. If interested, you will be joining a great team of committed researchers and teachers. 👇 www.med.ubc.ca/careers/admi...

My alma mater, the University of British Columbia, Dept of Medical Genetics, is hiring for a tenure track junior faculty position specializing in chromatin regulation / gene regulatory mechanisms. Beautiful city and vibrant epigenetics research. Please share! medgen.med.ubc.ca/assistant-pr...

Happy to share the lab's latest publication from @eli-elder.bsky.social and team in @narjournal.bsky.social ! What happens when #DNAmethylation maintenance is transiently interrupted in mouse embryonic stem cells? Let's dive in (1/11). doi.org/10.1093/nar/...

Happy to share the lab's latest publication from @eli-elder.bsky.social and team in @narjournal.bsky.social ! What happens when #DNAmethylation maintenance is transiently interrupted in mouse embryonic stem cells? Let's dive in (1/11). doi.org/10.1093/nar/...

NOUVELLE PUBLICATION | Rescuing DNMT1 fails to fully reverse the molecular and functional repercussions of its loss in mouse embryonic stem cells - par E. Elder et coll. @sergemcgraw.bsky.social tinyurl.com/2pucty86

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Excited to share the latest work from our lab - published in @devbiol.bsky.social! can01.safelinks.protection.outlook.com?url=https%3A... Congratulations Avery, @bnatale.bsky.social , Matthew Tang, Megan Cull and Nicki Peterson!

Now that’s a snowstorm! Already shovelled my driveway twice and still going on strong! #MontrealSnowStorm

We should all be taking to the streets. March 7. DC, state capitols, other big cities. Go to the website and sign up. Honestly, what the hell else will it take?

I really hope this snowstorm picks up... So far, it’s a letdown! Even our lab trainees who’ve never seen snow before aren’t impressed. #MontrealSnowStorm Just saying. ❄️😅

The department of biochemistry and molecular medicine at the Université de Montréal has a job opening for an assistant/ associate professor in the field of cryo-EM and its use to study fundamental questions in biology. Please email me for details or contact the department chair, Dr. Pascale Legault.

This International Day of Women and Girls in Science, we celebrate the brilliant women in our community and highlight articles by #WomeninScience to keep the conversations going(1/3) @davislab.bsky.social discusses gender inequalities in academia and shares her story of becoming a mother-scientist:

🚨 The Ghersi Lab is Hiring! 🚨 If you're passionate about hematopoietic stem cells, developmental biology, and cutting-edge research, I’d love to hear from you. Feel free to share. 🩸🐠 📍 Montreal, Canada 📩 [email protected] and Ghersilab.com

We're hiring a motivated PhD student! Join reNEW @ucph.bsky.social & @nucleardn.bsky.social to study how metabolism regulates chromatin & stem cell fate thanks to generous Marie Skłodowska-Curie Fellowship. Remember to apply both at shorturl.at/yf7Qq & nuclear-dn.eu.

We all have a few good days and many bad months during the year…The last 10 days have been just amazing for the lab. Major paper accepted, major funding, seeding grants, various PI and trainee awards, thesis completed… If this could be the normality! But tonight we celebrate! 🍾

Congrats! Especially our Lab's trainees : Diego Camacho, Josianne Clavel, and Charlotte Le Monies de Sagazan for Awards!! 🏆

Subventions Projet des Instituts de recherche en santé du Canada : 8,66M$ pour des projets de recherche au CHU Sainte-Justine! tinyurl.com/mr2e4cb3