Jesse Shapiro
@bjesseshapiro.bsky.social
📤 1766
📥 759
📝 462
Macrobe qui aime les microbes
http://www.shapirolab.ca/
pinned post!
One of my favourite serendipitous results from the lab came about because we were long-read sequencing bacterial: Vibrio cholerae, which is "supposed to" have TWO circular chromosomes (3 + 1 million base pairs) often has just ONE fused chromosome (4 Mbp).
www.nature.com/articles/s41...
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Prevalent chromosome fusion in Vibrio cholerae O1 - Nature Communications
The pathogenic bacterium Vibrio cholerae typically has two circular chromosomes. Here, Cuénod et al. analyse 467 clinical isolates and identify several independent chromosome fusion events that are li...
https://www.nature.com/articles/s41467-025-60699-0
7 months ago
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Zamin Iqbal
about 2 hours ago
A long time ago in a galaxy far away, there was a SARS-CoV-2 pandemic. Our paper, led by
@martibartfast.bsky.social
a) correcting errors in 4.5 million genomes & their phylogeny b) improving representation of the Global South in public data
www.nature.com/articles/s41...
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Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny - Nature Methods
This Resource paper presents a global SARS-CoV-2 phylogenetic tree of 4,471,579 high-quality genomes consistently constructed by Viridian, an efficient amplicon-aware assembler.
https://www.nature.com/articles/s41592-025-02947-1
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John Lees
about 6 hours ago
How do bacterial pangenomes evolve, what controls their dynamics, why do they exist? Fitting a mechanistic model to 450 species from
allthebacteria.org
suggesting fast vs slow gene exchange (i.e. amount of MGEs) is a major differentiating factor, correlated with phylogeny rather than lifestyle
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Olympic hockey on the big screen and soup simmering in the kitchen.
2 days ago
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Daniel Bolnick
4 days ago
New preprint from our big collaborative evolution experiment in 9 whole lakes in Alaska, written by McGill grad student
@lucaseckert.bsky.social
www.biorxiv.org/content/10.6...
What happens if you put a mixture of multiple source populations together to complete & evolve in multiple new lakes?
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Stephen Heard
3 days ago
Excellent classification.
xkcd.com/3204/
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Dinosaurs And Non-Dinosaurs
https://xkcd.com/3204/
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BF Francis Ouellette
4 days ago
This is the final week to submit your abstract to the Canadian Bioinformatics Hub Conference 2026 |
#ActNow
#Bioinformatics
#OpenScience
#Toronto
#Canada
#GreatScience
🧬 🖥️ 🧪 🔓 ⬇️
www.iscb.org/cbhc2026/
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Montreal in February: we eat so much poutine that our dumpsters are overflowing with 180L vats of poutine sauce. This message brought to you by Tourisme Montréal
4 days ago
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Paul Turner Lab
5 days ago
How does population density affect evolutionary trajectory? Microbes construct their own niche which in turn reshapes their evolution. Preprint drop from grad student
@noahhoupt.bsky.social
whose evolution experiments featured blue/white colonies, 1000 generations, a lab move, and much more!
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Dave Baltrus 🦦
6 days ago
Hey y’all, New paper out from the lab in Microbial Genomics, starting down the rabbit hole of IS elements in Paeudomonas syringae
www.microbiologyresearch.org/content/jour...
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Independent, ongoing clade-specific expansions of IS5 elements in Pseudomonas syringae
Insertion sequence (IS) elements are transposable regions of DNA present in a majority of bacterial genomes. It is hypothesized that differences in distributions of IS elements across bacterial strain...
https://www.microbiologyresearch.org/content/journal/mgen/10.1099/mgen.0.001613
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How your email finds me today
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6 days ago
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Jonathan Eisen
8 days ago
Rereading these two papers: Holes in the hologenome: why host-microbe symbioses are not holobionts.
journals.asm.org/doi/10.1128/...
The Hologenome Concept: Helpful or Hollow?
journals.plos.org/plosbiology/...
And I still find myself in general agreement with most of the points in them
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Holes in the Hologenome: Why Host-Microbe Symbioses Are Not Holobionts | mBio
ABSTRACT The advent of relatively inexpensive tools for characterizing microbial communities has led to an explosion of research exploring the diversity, ecology, and evolution of microbe-host systems...
https://journals.asm.org/doi/10.1128/mbio.02099-15
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Montreal Gazette
8 days ago
Anti-ICE demonstration being held in downtown Montreal Sunday
montrealgazette.com/news/local-n...
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Isabel
10 days ago
People always say, “oh, but what if ‘zero tolerance for sex pests’ gets earth’s rare geniuses fired?!?” as though many of these manipulative creeps haven’t also manipulated their way into professional positions far above their skill level…
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Tonight’s film selection
10 days ago
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Oliver Moore
11 days ago
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Laurie Belcher
11 days ago
Calling all OrthoFinder users! We’ve just released GLADE, a tool to infer gene gains, losses, duplications, and ancestral genomes across a phylogeny. GLADE runs directly on OrthoFinder results.
www.biorxiv.org/content/10.6...
github.com/lauriebelch/...
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https://www.biorxiv.org/content/10.64898/2026.01.27.702036v1
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Keith Robison
15 days ago
ONT Axes P2 Solo, Roiling Community 🧬🖥️
omicsomics.blogspot.com/2026/01/ont-...
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ONT Axes P2 Solo, Roiling Community
Oxford Nanopore has a serious case of user community unrest, triggered by the announcement that the P2 Solo (aka P2s) will be phased out sta...
https://omicsomics.blogspot.com/2026/01/ont-axes-p2-solo-roiling-community.html?m=1
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Bruce Springsteen
12 days ago
I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good. Stay free
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Bruce Springsteen - Streets Of Minneapolis (Official Audio)
YouTube video by Bruce Springsteen
https://youtu.be/wWKSoxG1K7w?si=7ciYwNLv34RrdD1p
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Nonia Pariente
12 days ago
The names of 72 female scientists will be added to the Eiffel Tower, to accompany those of 72 male scientists that are already engraved there
tinyurl.com/e2satnyp
👏👩🔬 🧪
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Locutus Tips
12 days ago
Locutus movie pick: The Breakfast Club. Five unique individuals discover that they are essentially the same and can be used as interchangeable components of a collective.
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Michael Hendricks 🇨🇦
14 days ago
I was maybe 2.5 years into my position as an Assistant Professor when my phone rang, and it was Kirsty Duncan, the new federal science minister, calling out of the blue. I had never met her. She asked me what she could do for early career investigators. /1
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Pleuni Pennings
19 days ago
Made a drawing to explain what a soft sweep is (and a hard sweep) in the context of drug resistance evolution in a viral population within a person's body. Anyone teaching about selective sweeps? Feel free to use.
#populationgenetics
#HIV
#drugresistance
#evolution
#PopulationGenomics
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MSU MGI
18 days ago
Vaughn Cooper’s new Scientific American article offers a clear look at the potential threats posed by mirror‑life. He trained with MGI's Rich Lenski
@relenski.bsky.social
, whose contributions to the field are referenced in the piece. Important context for a complex topic.
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Zamin Iqbal
17 days ago
Thread!
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Paul Carini
18 days ago
Excited to see this published! A big part of why SAR11 is so tricky to grow like "normal" microbes.
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Cool study showing in exquisite details what every parent of kids in daycare already knows...
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19 days ago
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Jesse Shapiro
Alex Crits-Christoph
20 days ago
Sad to hear that Oxford Nanopore wants to discontinue the P2Solo later this year in favor of the P2i (the very pricey P2Solo that comes with a GPU to do the basecalling in it) It feels like such a big step in the wrong direction. They are a great sequencing company, not a great GPU upseller...
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nanoporetech-customers - Sign In
https://community.nanoporetech.com/posts/product-update-p2
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A. Murat Eren (Meren)
20 days ago
We just released
#anvio
v9, "eunice" 🎉 This version represents over 2,000 changes in the codebase since v8, increasing the total number of programs in the anvi'o ecosystem to 176. Read the release notes:
github.com/merenlab/anv...
Visit our up-to-date web page:
anvio.org
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unraveled
21 days ago
God bless the United States of Minnesota
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Christian Landry
21 days ago
Another way in which Denmark is helping the US!
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Luís M. Silva
23 days ago
Call for abstracts ENDS MONDAY!! details below :)
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Oh The Urbanity!
23 days ago
Montreal’s snow removal operation — snow is trucked away from streets to snow dumps — is really effective. But also *expensive*. Each centimetre collected across the city costs $1 million. An operation collecting 15 cm of snow costs $15 million. The city does it about half a dozen times a year.
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Steven Salzberg
24 days ago
very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone.
www.embl.org/news/embl-an...
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In remembrance of Peer Bork | EMBL
EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.
https://www.embl.org/news/embl-announcements/in-remembrance-of-peer-bork/
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Rachel M. Wheatley
25 days ago
🚨4-year fully funded PhD in the lab of
@magicmicrobe.bsky.social
(& collaborating with me!): How does iron availability shape the ability of pathogens to invade the gut microbiome? Apply by Jan 26th Advert:
research.reading.ac.uk/foodbiosyste...
How to apply:
research.reading.ac.uk/foodbiosyste...
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https://research.reading.ac.uk/foodbiosystems/wp-content/uploads/sites/145/2025/12/FBS2026-69-Sharp-rq-AD.pdf
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Trying to keep these vibes in my heart and mind as I digest (yet another!) rejected grant.
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24 days ago
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First lab lunch of 2026! There’s not a lot to love about the year so far but getting to hang out with this cool gang on a daily basis keeps me going.
26 days ago
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Chris MacQuarrie
26 days ago
Peer Review is broken because a generation of Editors were trained that peer review is sacrosanct. Thus we have Editors who are clerks, sending and re-sending manuscripts to reviewers until they are happy. That's not the job. Be an Editor, not a clerk. Use your skill and judgement. Make decisions.
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Guillaume Larocque
27 days ago
Our new paper on BON in a Box is out! 📦 This project has high ambitions: linking biodiversity science to meaningful policy, transforming messy data into useful metrics. 🐝 🌳 📊 💡 Our vision is to make biodiversity science more user friendly, powerful and accessible!
academic.oup.com/bioscience/a...
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BON in a Box: An Open and Collaborative Platform for Biodiversity Monitoring, Indicator Calculation, and Reporting
Abstract. The Convention on Biological Diversity’s Kunming–Montreal Global Biodiversity Framework (GBF) sets ambitious goals to protect and restore biodive
https://academic.oup.com/bioscience/advance-article/doi/10.1093/biosci/biaf189/8424339?utm_source=authortollfreelink&utm_campaign=bioscience&utm_medium=email&login=true
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Joshua Weitz
28 days ago
Viruses transform microbes, populations, & ecosystems. In new work jointly led w/@tn-marine-micro.bsky.social + more, we find a link between enhanced viral infection and productivity 50 meters below the surface in the otherwise nutrient limited Sargasso Sea. a 🧵
www.nature.com/articles/s41...
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Locutus Tips
2 months ago
Locutus safety tip: To prevent identity theft, avoid having your own identity.
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Very cool paper, and I look forward to the fight with the copy editor about whether it should be "deletion-born fusions" or "deletion-borne fusions"! (I think both could work?!)
add a skeleton here at some point
about 1 month ago
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/r/Habs
about 1 month ago
There’s no place in the NHL like the Bell Centre in Montreal. Just listen to the Habs crowd on Alexandre Texier’s hat trick goal 🔥
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Vaughn Cooper
about 1 month ago
🚨Call for papers🚨 Microbial Evolution: Impacts on Human Health in the society journal Evolution, Medicine, and Public Health Guest Editors: Bob Woods, Silvie Huijben & Camilo Barbosa EIC: me This will be great, please submit and share!
academic.oup.com/emph/pages/m...
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Mel Buer
about 1 month ago
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T. Green, MLS 👩🏽💻📚🇵🇭🇺🇲
about 1 month ago
Enjoy this again from one of the "untenured faculty members and staff holding the institution together." (Sobs at markout of the office of diversity, equity, and inclusion)
#AcademicChatter
#AcademicHumor
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An Accurate Organizational Chart of Your University
Our 20th most-read article of 2025. - - -In accordance with our informal tradition of updating documents every thirty years, whether they need it ...
https://www.mcsweeneys.net/articles/an-accurate-organizational-chart-of-your-university
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Rebecca R Helm
about 1 month ago
The world feels rough right now So please enjoy this shrimp, filmed off Cozumel, Mexico. It may be a larval reef shrimp, but we don’t know what species or how long it lives or what it eats. The world is still full of wonder and beauty and mystery. 🎥 @pedrovalenciam scuba diver on Insta
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Heather Hendrickson
about 1 month ago
We’re looking for a postdoc to join the Hendrickson lab! The project will involve dissecting the molecular mechanisms of a fascinating mobile element in our honeybee biocontrol phages. Sound like something you would be interested in? Get in touch! Details:
jobs.canterbury.ac.nz/jobdetails/a...
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Research Associate / Postdoctoral Fellow - Honeybee Bacteriophages and Advanced Biotechnology - University of Canterbury | Te Whare Wānanga o Waitaha
https://jobs.canterbury.ac.nz/jobdetails/ajid/ZDWZ9/Research-Associate-Postdoctoral-Fellow-Honeybee-Bacteriophages-and-Advanced-Biotechnology,30301
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McGill Global Health Programs
about 1 month ago
Applications are now open for the 2026 Global Health Scholars program. McGill undergraduates from all faculties and programs can gain hands-on global health research experience with a faculty supervisor during summer 2026 and receive up to $6,000 in funding.
www.mcgill.ca/globalhealth...
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The Onion
about 1 month ago
RFK Jr. Recommends Drinking Anything That Comes Out Of Cow
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bioRxiv Microbiology
about 1 month ago
Within-host adaptive evolution is limited by genetic drift in experimental human influenza A virus infections
https://www.biorxiv.org/content/10.64898/2026.01.07.698006v1
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