Jesse Shapiro
@bjesseshapiro.bsky.social
📤 1859
📥 824
📝 597
Macrobe qui aime les microbes
http://www.shapirolab.ca/
pinned post!
Now out & nicely formatted in
@isme-microbes.bsky.social
A big analysis of ocean genomes & metagenomes co-led by former postdocs, now PIs,
@gmdouglas.bsky.social
&
@cyanophage.bsky.social
along with co-PIs
@lbobay.bsky.social
& Samuel Chaffron. A few highlights... 🧵 (1/n)
doi.org/10.1093/isme...
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Co-occurrence is associated with horizontal gene transfer across marine bacteria independent of phylogeny
Abstract. Understanding the drivers and consequences of horizontal gene transfer (HGT) is a key goal of microbial evolution research. Although co-occurring
https://doi.org/10.1093/ismejo/wraf275
5 months ago
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Greg Annandale
about 16 hours ago
I made an animation which shows the effects of air pollution on pedestrians waiting to cross the road, along with what can be done to reduce its harmful effects:
stepback.gregdev.com
Thank you to
@ianwalker.bsky.social
for the inspiration for doing so during a conversation a couple of weeks' back!
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'Step back' - air pollution at pedestrian crossings
Every busy road produces a cloud of pollution you can't see. Where you stand in it matters more than most people might realise.
https://stepback.gregdev.com/
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Lewis C. E. Mason
1 day ago
By Julia Marshall as first author and led by Professors Kate Baker and Henrik Salje as co-leading authors (
@hsalje.bsky.social
@ksbakes.bsky.social
), please see our new article about the genomic epidemiology of the spread of sexually transmitted
#Shigella
:
www.thelancet.com/journals/lan...
🛟🧪🧬🖥️🦠💉🧫😷
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The spread of sexually transmissible drug-resistant shigellosis in England: a genomic epidemiology study
Our study shows the distinct and intensifying sexual transmission of shigellosis, highlighting the urgent need to address sexually transmissible shigellosis as a distinct health threat. Traditional in...
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00227-6/fulltext
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Must find a way to play these. Where is my MD player?!
2 days ago
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Jesse Shapiro
Alex Crits-Christoph
5 days ago
What are your favorite papers that linked patients, traced outbreaks, or distinguished epidemiological hypotheses on the careful basis of just a few SNVs? Like ~ <20? Bacterial best, viruses OK too
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Sabbatical year in France is HAPPENING !!
6 days ago
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Jesse Shapiro
Kristian G. Andersen
6 days ago
This is possibly the best thing I have read on Bluesky since I joined a few years ago. It is that on-point. What we are observing isn't "polarization", it's "radicalization". This can be applied not just to politics, but also many other things in the public discourse - COVID being one close to me.
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MEEhubs
6 days ago
🚨The program for MEEHubs2026 is now online, as is more detailed information about the hubs! Check it out at
meehubs.org
and register‼️ Less than a month before the conference kicks off! 🦠
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Home
A hub-based conference on Microbial Ecology and Evolution
https://meehubs.org
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Jesse Shapiro
Alex Diaz-Papkovich
7 days ago
Built a proof-of-concept interactive map based on the news stories I collected: 2,202 incidents involving 1,724 pedestrians, 400 cyclists, 279 others, and 252 structures.
diazale.github.io/death_by_car/
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Jesse Shapiro
C. Brandon Ogbunu
11 days ago
New for
@undark.org
: Mathematicians have signed the Leiden Declaration for AI. I argue that the life sciences needs one: built for noisy, context-dependent systems, w/ disclosure, human accountability, wet-lab validation, & rules that evolve as fast as the tools do.
undark.org/2026/07/02/o...
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Biologists Should Articulate Their Position on AI
Opinion | In the Leiden Declaration, mathematicians issued a treatise on how AI challenges their field. Others must do the same.
https://undark.org/2026/07/02/opinion-biologists-leiden-declaration/
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Jesse Shapiro
Canadian History Ehx
13 days ago
Today is Moving Day in Quebec. Every year on this day, thousands of Quebec residents load up trucks and vans to move residences. The origin of Moving Date dates back centuries to the era of New France. This is the story. 📸 Montreal Gazette Archives 🧵 1/7
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Jesse Shapiro
Dave Baltrus 🦦
17 days ago
I am now old enough that perspective pieces are being written about articles I read in grad school the day they came out (and which definitely changed how we think about the world)
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Jesse Shapiro
Paul Rainey
17 days ago
I really value: the dynamics of community assembly on 2 contrasting C sources. Daily sampling of communities derived from compost & maintained over 8 wks. No difference in diversity maintained on simple or complex C. AmaZinG. 🙏 all
enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
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Diverse Microbial Communities Assemble on Both Recalcitrant and Labile Carbon Sources
Taxonomically and functionally distinct communities assemble on cellulose and its monomer, glucose. Although single carbon sources were provided, high and comparable diversity was maintained in both ...
https://enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/1462-2920.70351
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Jesse Shapiro
Kayla King, Ph.D.
20 days ago
Evolutionary rescue in a phage community! New paper from former PhD student, Sam Greenrod, with brilliant colleague
@craigmaclean.bsky.social
:
academic.oup.com/ismej/advanc...
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Rapid adaptation accelerates competitive suppression in a parasite community
Abstract. Environmental stress leads to changes in community composition by altering competitive hierarchies and pushing taxa towards extinction. Parasites
https://academic.oup.com/ismej/advance-article/doi/10.1093/ismejo/wrag114/8707356?login=false
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Any other weirdo/luddites like me listing to the game on TSN radio are being treated to delightful Scottish-accented play-by-play
add a skeleton here at some point
19 days ago
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Love the
#worldcup
flag combos that appear in Canada but I doubt would be viable in their home countries…
19 days ago
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Bonne St-Jean tout le monde!
add a skeleton here at some point
20 days ago
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Jesse Shapiro
Lucy van Dorp
23 days ago
We are advertising a 3-year Evolution Education Trust funded
#PhD
studentship at
@ugiatucl.bsky.social
UCL to investigate the genomic history of infectious diseases preserved within historical pathology collections. Details:
www.findaphd.com/phds/project...
.
#findaphd
#EET
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Unlocking the Genomic History of Pathogens Through Pathology Archives at University College London on FindAPhD.com
PhD Project - Unlocking the Genomic History of Pathogens Through Pathology Archives at University College London, listed on FindAPhD.com
https://www.findaphd.com/phds/project/unlocking-the-genomic-history-of-pathogens-through-pathology-archives/?p197455
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Jesse Shapiro
Chris Hutchinson 🇺🇸🇺🇦🇬🇱🇵🇸🇮🇷 🕊️
23 days ago
alright, who did this?
#hatm
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Green roof at the local library is so cheerful on a rainy day
23 days ago
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Jesse Shapiro
Andrew Roger
25 days ago
1/ Deep-time phylogenetics is hard: overly simplistic substitution models can mislead tree estimation at the billion year timescale. Our new preprint introduces GTRspmix, a protein modeling framework designed to more realistically model site-to-site heterogeneity in amino acid replacement. 🧵
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Jesse Shapiro
Tu Thanh Ha
25 days ago
The top scorers at the World Cup right now, with 3 goals each, are Jonathan David and a guy named Messi.
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Jesse Shapiro
Tom Hawthorn 🇨🇦
25 days ago
Charlie Demers: "I mean the match up hardly seems fair… a sparsely-populated petro-state cowering in terror of its neighbours versus Qatar."
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Jesse Shapiro
Colin Carlson
25 days ago
Potential postdoc opportunity! We're looking for someone to do Good Work Fast at the interface between zoonotic disease ecology and global climate and land-use projections. Strong skills in statistics and geospatial modeling are the non-negotiable here. In-person in New Haven. More essential info 👉
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Jesse Shapiro
Noah Fierer
25 days ago
Ever wanted to use metagenomic data to infer oxygen levels (or the oxygen preferences of whole bacterial communities)? We have the tool for you:
journals.asm.org/eprint/9GUIR...
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Predicting oxygen levels in microbial habitats using a metagenome-based approach | mSystems
Oxygen is one of the most important environmental variables affecting microbial activity and composition, but is often difficult to measure in situ. We developed a tool, OxyMetaG, that leverages diffe...
https://journals.asm.org/eprint/9GUIRNW778PFEPBVJEKM/full
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Jesse Shapiro
Jim Sylvester
25 days ago
Make Algae Grow Again
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Uh, what?!
add a skeleton here at some point
26 days ago
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Jesse Shapiro
Louis Ates
about 1 month ago
I'm incredibly proud to share our paper on the preclinical evaluation of the BNT164 mRNA tuberculosis vaccine candidates. Now online in the final version at Nature Immunology.
www.nature.com/articles/s41...
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mRNA-based tuberculosis vaccines BNT164a1 and BNT164b1 are immunogenic, well tolerated and efficacious in rodent models - Nature Immunology
Here the authors characterize mRNA-based tuberculosis vaccine candidates BNT164a1 and BNT164b1 and show that they are immunogenic, well tolerated and efficacious in preclinical animal models.
https://www.nature.com/articles/s41590-026-02545-z
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Jesse Shapiro
Parvathi Vijay
4 months ago
Beyond ecstatic! A huge thanks to the editors
@alejandrofabregastejeda.com
@ennofischer.bsky.social
, the reviewers, and the wonderful team at
@philinbiomed.bsky.social
for all their feedback!!
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Jesse Shapiro
Leonora Bittleston
27 days ago
Can we use ecological principles to increase coexistence in synthetic bacterial communities? Our new paper is now out in
@isme-microbes.bsky.social
: "Environmental complexity shapes maintenance of bacterial diversity through context-dependent interactions among niche axes"
doi.org/10.1093/isme...
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Environmental complexity shapes maintenance of bacterial diversity through context-dependent interactions among niche axes
Abstract. Microbial communities are often more species-rich than predicted from classical ecological models. The high levels of coexistence observed in nat
https://academic.oup.com/ismej/advance-article/doi/10.1093/ismejo/wrag144/8706321
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How useful are phages in explaining cholera disease severity? Accordingly to our latest little paper, possibly quite useful — up there with patient age and hospital location, and possibly more important than antibiotic exposures!
add a skeleton here at some point
28 days ago
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Applied Math
about 1 month ago
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Jesse Shapiro
Dor Salomon
about 1 month ago
🚨Our collaboration with the Bar Yaacov lab on A-to-I mRNA editing in
#Vibrio
is online🚨🦠 Exciting findings on what genes are edited and the physiological implications. Hint: It affects
#T6SS
activity and reveals a possible new role for CqsA.
www.biorxiv.org/content/10.6...
@rinatcp.bsky.social
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Re-upping for morning phage phriends. Hope you will find Brenna & Patrick's method useful! Here they are, with some other lab members, on a rock. They are rock stars.
add a skeleton here at some point
about 1 month ago
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Jesse Shapiro
sylvain Brisse
about 1 month ago
It's out! The LIN code approach for genomic taxonomy of microbial strains and its applications in genomic epidemiology
journals.plos.org/plosbiology/...
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Life Identification Numbers: A strain nomenclature approach to aid epidemiological surveillance of bacterial pathogens
Unified bacterial strain taxonomies are needed for coherent communication of findings in microbiological research. This Essay provides an overview of a novel bacterial strain taxonomy and describes ho...
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003781
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Cheap and easy method for nanopore sequencing phage DNA directly from plaques. Proud of lab members Brenna and Patrick for doing this work *with absolutely no help from me* !!
www.nature.com/articles/s41...
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Same-day tagmentation PCR-based whole genome sequencing of bacteriophage genomes from a single plaque without DNA extraction - Scientific Reports
Scientific Reports - Same-day tagmentation PCR-based whole genome sequencing of bacteriophage genomes from a single plaque without DNA extraction
https://www.nature.com/articles/s41598-026-55253-x
about 1 month ago
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Jesse Shapiro
Kristian G. Andersen
about 1 month ago
This is extremely chilling - virologists being targeted for what appears to be minor (if any) "offenses". We all know _why_ this is happening, so I'm not going to belabor that point - but I want to provide some context on the technical details. 🧵
www.science.org/content/arti...
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NIH scientists plead not guilty to smuggling monkeypox viruses into U.S.
Defendants face prison time for criminal charges but samples may all have been inactivated and used for routine diagnostics
https://www.science.org/content/article/nih-scientists-criminally-charged-bringing-monkeypox-virus-us-although-samples
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Jesse Shapiro
S Otto
about 1 month ago
Why we’re concerned about “Getting Major Projects Built in Canada” 👀 and its impact on nature and a healthy environment. Have your voice heard - read the govt’t proposal
www.canada.ca/en/one-canad...
and email feedback to
[email protected]
by June 7, 2026 🙏@baumlab.bsky.social
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Jesse Shapiro
Craig MacLean
about 1 month ago
Excited to share this new paper from the lab:
academic.oup.com/ismej/articl...
! See thread below
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Eco-evolutionary responses to plasmid-dependent phage constrain the spread of multidrug-resistance plasmids
Abstract. Phage therapy offers an alternative to antibiotics for treating multidrug-resistant infections. Plasmid-dependent phages (PDPs) are promising the
https://academic.oup.com/ismej/article/20/1/wrag113/8673213
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Jesse Shapiro
Salvador Almagro-Moreno
about 1 month ago
Vibriophiles! Come join us in Berlin this September! Still time to register and submit your abstract
add a skeleton here at some point
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Jesse Shapiro
Kristian G. Andersen
about 1 month ago
On OMB's proposal to make all grants political: "Speak up! Now’s the time! Standing by the side of the room, glancing around nervously and hoping that somebody else does something will lead us to disaster. These are not normal times, so stop acting as if they are."
www.science.org/content/blog...
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Action! Action Now.
https://www.science.org/content/blog-post/action-action-now
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Jesse Shapiro
Dr. Kat Napaaqtuk❄️
about 1 month ago
Happy Pride Month y'all!
add a skeleton here at some point
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Jesse Shapiro
Duncan MacCannell
about 1 month ago
This little fella shook my house.
www.cbsnews.com/boston/news/...
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Meteor explodes off Massachusetts coast, causing loud boom, meteorologist confirms
A meteor exploded off the coast of Massachusetts, causing a loud boom to be heard throughout the state Saturday afternoon, according to WBZ-TV Chief Meteorologist Eric Fisher.
https://www.cbsnews.com/boston/news/massachusetts-coast-meteor-explodes-loud-boom/
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Hard to stay sad about the Habs with these vibes! Let’s go Victoire! Championnes!!
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about 1 month ago
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Jesse Shapiro
Timothée Poisot
about 2 months ago
once again vanilla ice is under pressure
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Jesse Shapiro
The Onion
about 2 months ago
Listerine Leaves 0.1% Of Germs Alive To Spread Message Of Terror Throughout Microbial Community
https://theonion.com/listerine-leaves-0-1-of-germs-alive-to-spread-message-of-terror-throughout-microbial-community/
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The headline sounds silly but Jérôme is awesome and this is great news for science in Québec. Félicitations Jérôme, you rock!!
montrealgazette.com/news/quebec-...
about 2 months ago
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Jesse Shapiro
Kristian G. Andersen
about 2 months ago
Our NIH-funded research - including as part of CREID - developed, deployed, and established capacity for many of the core tools and countermeasures used during outbreaks. Diagnostics, sequencing, monoclonals and vaccines. As we're facing a new foe with none of those, all that work, defunded. Gone.
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Jesse Shapiro
McGill University
about 2 months ago
Convocation season is officially ON 🎓✨ Big smiles, proud moments, and the start of something new! Congratulations to all
#McGillGrads
of the Class of 2026! 🎉
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Jesse Shapiro
Jonathan Eisen
about 2 months ago
A very important preprint to check out: The holobiont is not a useful model for most host-microbiome interactions By Gavin M Douglas an S. Andrew Inkpen
ecoevorxiv.org/repository/v...
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The holobiont is not a useful model for most host-microbiome interactions
https://ecoevorxiv.org/repository/view/13115/
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