It's not #FluorescenceFriday but unexpectedly beautiful data should always be celebrated 💚 #PKMO -stained #mitochondria cristae in #STED

FLASH-AWAY: Intrabody-Directed Targeting of Optogenetic Tools for Protein Degradation: pubs.acs.org/doi/10.1021/...

Systems biology view on mitochondrial dynamics, I like it 🤩

Beyond Static Screens: A High-Throughput Pooled Imaging CRISPR Platform for Dynamic Phenotype Discovery by Kees Jalink and team: www.biorxiv.org/content/10.1...

Hi everyone! I’m new to Bluesky. At the beginning of the year, I moved to Zurich @UZH_en to start a postdoc with #CyrilZipfel and @pedrobeltrao.bsky.social, investigating protein phosphorylation in plants 🌱 If you’re nearby or working on something similar, let’s connect 😀

🌍Euromit 2026 is coming to Angers!🌍 ✨The international congress dedicated to mitochondrial research, will take place in France, at the Centre des Congrès of Angers. from May 31 to June 4, 2026! ✨ 📢 Stay informed by following this page and get ready for an exceptional scientific experience! 🚀🔬

Impairing mitochondrial fusion triggers a vicious cycle of unequal mitochondrial inheritance and failed mtDNA synthesis that rapidly depletes mtDNA: www.biorxiv.org/content/10.1...

Origin and evolution of mitochondrial inner membrane composition journals.biologists.com/jcs/article/...

Intracellular metabolic gradients dictate dependence on exogenous pyruvate www.nature.com/articles/s42... Congrats to @lydiafinley.bsky.social Lab!

Very cool work from the @katajistolab.bsky.social ! Congratulations to the team!

Bluesky has overtaken its flailing rival X in hosting posts related to new academic research, indicating the platform is fast becoming the go-to place for scholars to share their work #AcademicSky #EduSky

Preventing Multimer Formation in Commonly Used Synthetic Biology Plasmids | ACS Synthetic Biology pubs.acs.org/doi/full/10....

Check out our new fluorescent probe for imaging f-actin dynamics: 𝗦𝗶𝗥-𝗫𝗔𝗰𝘁𝗶𝗻: 𝗔 𝗳𝗹𝘂𝗼𝗿𝗲𝘀𝗰𝗲𝗻𝘁 𝗽𝗿𝗼𝗯𝗲 𝗳𝗼𝗿 𝗶𝗺𝗮𝗴𝗶𝗻𝗴 𝗮𝗰𝘁𝗶𝗻 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 𝗶𝗻 𝗹𝗶𝘃𝗲 𝗰𝗲𝗹𝗹𝘀 www.biorxiv.org/content/10.1... Thank you @veselin-nasufovic.bsky.social

In-cell architecture of the mitochondrial respiratory chain | Science www.science.org/doi/10.1126/...

Join us at the ICSB in Dublin this October - I will chair the session on aging systems biology icsb2025.com

Interesting preprint about ATP gradients within cells: www.biorxiv.org/content/10.1...

Why do cortisol-lowering drugs work for Cushing’s but fail in mood disorders & chronic stress? We propose that the ability of the pituitary and adrenal glands to adjust their functional masses—normally beneficial—counteracts the drug’s effect. Using a math. model, we screened HPA interventions (1/2)

Great to see the mTurquoise2 plasmids that we've generated used as markers of subcellular structures rupress.org/jcb/article/...

🧵Prepint alert! Optimizing Multifunctional Fluorescent Ligands for Intracellular Labeling | tinyurl.com/3n55hvsc. With Jason Vevea, Ed Chapman, and @so-lets-kilab70.bsky.social, we combined dye chemistry, HaloTag, microscopy and cell biology to make protein purification and manipulation tools.

Mito-friends: What conferences are we attending this year? I ask because there are no mito/cyto symposia at my usual conferences, and it would be great to catch up! 🔬🧪

Our global study on the state of trust in scientists is now out in Nature Human Behaviour! 🥳 With a team of 241 researchers, we surveyed 71,922 people in 68 countries, providing the largest dataset on trust in scientists post-pandemic 👇🧵https://www.nature.com/articles/s41562-024-02090-5

Pericentromeric #heterochromatin clusters into chromocenters. @skrutlnize.bsky.social &co use quantitative mass spec to characterize the chromocenter proteome in multiple tissues, identifying a link between satellite DNA-binding proteins & #transposon repression🧪 @plosbiology.org plos.io/4akuNAi

FLIM imaging reveals IMM lipid heterogeneity in live cells. Find out more about this exciting tool: onlinelibrary.wiley.com/doi/10.1002/...

Stoked to share TWO preprints on mitochondrial pearling! 🎉 We uncover how spontaneous #mitochondria pearling drives #mtDNA nucleoid distribution (doi.org/10.1101/2024...), and @gavsturm.bsky.social et al. dissect the biophysics behind it (doi.org/10.1101/2024...). Details below! 🔬🧵🧪

The dark side of fluorescent protein tagging: the impact of protein tags on biomolecular condensation www.biorxiv.org/content/10.1...

A highly photostable monomeric red fluorescent protein www.researchsquare.com/article/rs-5...

Interesting article: rupress.org/jcb/article/...

Vimentin-mSG FRAP

Struggling with proof-reading? A reminder that MS Word can read your document back to you via the 'read aloud' funciton found in the 'review' tab. An absolute game changer!

Oh, Switzerland, you pretty.

Looks interesting: www.sciencedirect.com/science/arti...

prelights.biologists.com/prelists/nov...

Tissue-specific adaptations to cytochrome c oxidase deficiency shape physiological outcomes 🧪 www.sciencedirect.com/science/arti... Congratulations to Milica Popovic and Lea Isermann from the Trifunovic lab for this nice work!

Very interesting approach to visualize proteins. www.nature.com/articles/s41...

Two cells photographed through a microscope. DNA in the nucleus and mitochondria in each cell are shown. #Science #Biology #CellBiology #microscopy

#Pearling in physiological neuronal axons!! 🤩📿

My turn to create a starter pack for scientists using live imaging in their research! Of course, I’ve likely missed many—please let me know who else I should include. Thanks! go.bsky.app/KYYr7xc #liveimaging #livevellimaging #microscopy

Hey blue skies- We have updated our latest #BioRxiv paper- We found that #mitochondria in #plants without mtDNA move and connect differently to those with mtDNA! Now featuring two different methods of measuring mtDNA and mitochondrial motility. Check it out: www.biorxiv.org/content/10.1...

Cool new work from the lab by @chris-morrow.bsky.social: Often we think of auto-fluorescence as a hindrance to experiments - but endogenous metabolites have specific fluorescence we can use to determine the metabolic state of the cell - and predict lifespan.. www.nature.com/articles/s42...

posting here since bsky is taking off! nature.com/articles/s41586-024-08146-w Congratulations to my good friend @keunwooryu.bsky.social and the Craig Thompson lab on uncovering metabolically distinct mitochondrial subpopulations. Really cool cell biology Keun!!

Finally moved to #Bluesky and happy to share our recent work! We found that hexokinase 1 rapidly forms rings around #mitochondria during energy stress to regulate mitochondrial fission: www.cell.com/molecular-ce... For a quick summary of our findings, check out the comment section.

Hey people! @florentwaltz.bsky.social was kind enough to make a pack for mito enthusiasts. Check it out and join/follow for updates on the most interesting organelle!

Visualizing mitochondrial membrane proteins in live cells can be challenging due to the size of fluorescent protein tags (~240 residues). In our recent paper, we show how a small tetracysteine tag (6 residues) enables accurate visualization of VDAC1 in live cells. journals.plos.org/plosone/arti...

How do #mitochondria decide when to divide or fuse? I’ve always thought mtDNA played a key role in this process, so I was very surprised by this finding: The loss of mtDNA does not affect mitochondrial fission and fusion rates. www.molbiolcell.org/doi/10.1091/...

Textbook oxidative phosphorylation needs to be rewritten with Fernando Abdulkader www.sciencedirect.com/science/arti... Free for 50 days here: www.sciencedirect.com/science/arti...

Trying to gather all the mitochondriacs that landed here Help me fill up this starter pack! Just ask and i'll add you 🤓 #Mitochondria #Mitochondriacs #Respiration #Organelle go.bsky.app/G1DPArc

🔬 Curious about #mitochondria #imaging but unsure where to begin? Our review might help! 🚀📜🧪 www.annualreviews.org/content/jour... #Quantitative #Microscopy #SuperResolution #AcademicSky #ScienceSky #CellBiology #mtDNA