Orchestrating Spatial Transcriptomics Analysis with Bioconductor https://www.biorxiv.org/content/10.1101/2025.11.20.688607v1

Today we celebrate the birthday of not one, but two amazing women in science! 🤗🎉Marie Skłodowska-Curie (1867), who discovered #radium & #polonium & pioneered #radioactivity, & Lise Meitner (1878), whose brilliance uncovered the physics behind #nuclearfission. Happy birthday, trailblazers! ✨

Statistical thinking is a core part of solid biological results. However, many studies still include insufficient sample sizes, have poor experimental design, or select incorrect statistical tests. Here, the authors present ten statistical tips for cell biology www.nature.com/articles/s41...

Applications are currently being accepted for UBC's ✨️ Biodiversity Postdoctoral Fellowship ✨️ (two positions!!), due Jan. 15 Please share far and wide 🚀 (See thread)

We’ve put up summary statistics for over 3,000 traits in the All of Us resource, and a shiny new browser alongside it! Explore your favorite gene or phenotype here: allbyall.researchallofus.org #ASHG24

We have progressed from data collection to data analysis.

🚨#job alert 🚨 I am recruiting a technician and #postdoc in #bioinformatics to investigate T cell transcription networks in skin and gut #inflammation. We are a growing and diverse team at @ubcmedicine.bsky.social. Links below: tinyurl.com/42w4vh7s tinyurl.com/4n5wva6c Please repost #immunosky

Just used this and was very impressed! It is also very nice to receive a robust scientific critique that does not include any personal comments. Reviewers #3 everywhere please take note...

‘Surprising’

Just in time for #ASHG2025, a new FinnGen public data release is live! This release features the first clinical laboratory value association results. Analyses cover 383 lab measurements (OMOPIDs) with data from ≥1,000 participants each. Access the results here: www.finngen.fi/en/access_re...

If anyone needs me I will be in the museum, lying down next to the bog bodies.

Super excited to announce the launch of the PhD subspecialization program in genetic & genomic counseling at @ubcmedicine.bsky.social - it's open to applications! All details including contact information for any questions is available here: medgen.med.ubc.ca/graduate-pro... Please share widely!

Hello everyone! I am a postdoc in mucosal immunology and I am looking for new postdoc position in Europe! I know a lot about gut mast cells, but also CD4 T cells and type 2/3 immunity in general. I've worked with single cell sequencing and neuroimmune interactions. Feel free to share! Thank you! ♥️🥼👩‍🔬

Editor searching reviewers in August

TYK2 inhibition enhances Treg differentiation and function while preventing Th1 and Th17 differentiation @cp-cellrepmed.bsky.social @mklevings.bsky.social cell.com/cell-reports...

Today is Generalised Pustular Psoriasis awareness day. The US National Psoriasis Foundation has a lot of resources for people living with this severe condition www.psoriasis.org/gpp-resource... #psoriasis, #dermatology, #RareDisease

My biggest, loudest job application advice: WHY do you want this job? This SPECIFIC job? What about it interests you? What do you think of it? What can you bring to it? I know this sounds obvious but a generic cover letter isn't doing you favours - really. *Show me you know the job!* 1/7

This is very true. My most productive time is between 5.00 and 7.00pm...which is why I am currently faffing around on Bluesky #Procrastination #AcademicChatter

🚨Our latest paper is out on the Br J Dermatol 🚨Using #MendelianRandomization, we identify OX40 as a likely disease mediator in palmoplantar pustulosis. Given OX40 inhibitors are in clinical development (for #eczema), this is exciting news! #skin, #inflammation tinyurl.com/mtezcub3

I feel seen...

Come join us in Vancouver! Exciting opportunity for a more senior investigator researching new regenerative medicine approaches for Type 1 diabetes. $8M in funding for successful candidate research.ubc.ca/media/file/j...

Thanks for the reminder @janemunday.bsky.social. Every summer, I repost this article DROWNING DOES NOT LOOK LIKE DROWNING. To date, I know of FOUR kids who were saved after someone who'd clicked on the link learnt how to spot actual drowning. Take time to read and pass on. slate.com/technology/2...

The latest preprint from our lab, led by the amazingly talented Lucia Ramirez Navarro. Do circulating immune cells capture the transcriptomic signatures of their counterparts in the inflamed gut? No, except for a rare population of T cells expressing tissue residency markers.

Hello @bsky.app! We’re excited to have made the transition over to BlueSky 🦋 and are already excited to be part of the fantastic #immunology community!

Weird intersection of math & centrifuge balancing: Visual proof that it's possible to balance a 24-position centrifuge rotor for any number of equally-filled tubes EXCEPT 1 and 23. Some of these are anxiety-inducing, though. (🧑‍🎨: aliyoh, labrats subreddit)

Can't remember who said it, but using ChatGPT for your college essays is like using a forklift to move the weights around at the gym. It's the process that's important to your development, not the end product.

Fully funded #PhD studentship available at @kingscollegelondon.bsky.social to investigate immune memory in #psoriasis using #singlecell methods. Great project supervised by Satveer Mahil with opportunities to visit my lab at @bcchresearch.bsky.social. Please RT. tinyurl.com/yp7jvudv #immunosky

Heard from a former (undergrad) student who just defended her PhD. Students: tell your old profs about your successes and achievements. It's not bragging, and we love to hear about it. It's one of the best parts of being an educator. #academicsky

Chilblains were reported in #SARSCoV2–exposed individuals without PCR- or serologically defined #COVID19. Saidoune, Gilliet , @ahmad-yatim.bsky.social et al. show that excessive TLR7 responses to SARS-CoV-2 by pDCs are linked to I-IFN–driven chilblain development. rupress.org/jem/article/...

UBC is hosting US Applicant Week from April 14-18, which allows US students to apply during an extended application period for graduate studies. Sixty graduate programs will be reopening applications for US applicants for September 2025 and January 2026 start dates - www.grad.ubc.ca/us-applicant...

Does anybody want to join in a movement to limit the number of supplementary figures in a paper? Am currently reviewing a manuscript and it never ends.. was it really worth adding 3 panels to Fig S10, just to make a minor point? (and yes, it is a #singlecell paper)

Ever stuck choosing the right plot or trying to figure out how to make it look just right? My go-to resource is the R Graph Gallery (r-graph-gallery.com), which is full of examples and clear code for everything from scatterplots to Sankey diagrams! #dataviz #rstats #rladies

When you lie on your resume, but still get the job 🐾🤭 📽️dogswithjobs

"Why don't you buy a new centrifuge" Because everyone knows that any appliances in that shade of yellow will outlive you and your entire family, look at it

New preprint! We worked with @msftresearch.bsky.social and @broadinstitute.org to see whether large language models (LLMs) can be useful to variant scientists in deciding whether genetic variants seen in a patient are responsible for their disease. tl;dr yes they can: www.biorxiv.org/content/10.1...

Labeling your axes and then explaining them slowly is perhaps the biggest bang for the buck you can get for making your slides more understandable.

No exodus to state sector after VAT added to private school fees, say English councils Most say they have seen no impact on applications for year 7 places, despite warnings from those against policy www.theguardian.com/education/20...

Good data is essential for research. But it can be hard for researchers to find it. The Atlas of Longitudinal Datasets is changing that. This free tool lets you explore thousands of datasets from all over the world. Learn more from @larseneault.bsky.social ⤵️ www.linkedin.com/pulse/creati...

Join leading experts working in #RareDisease research at our #GRD25 conference. 📅 Dates: 9-11 April 2025 💭 Share insights in person Explore the latest #genomics advances accelerating improvements in clinical care for rare disorders, globally. ⏰Secure your place by 11 March: bit.ly/3BpAe44

Hello, Bluesky!👋 We are excited to connect with you!🌟 Europe PMC is an open database of global life science research - discover articles, preprints, theses, grants, and more. We talk about scholarly communication, open science, bioinformatics, and meta research. Follow us and join the conversation!

Bioinformatics Post-Doc Opportunity Vancouver Canada Come grow your genome analysis and processing skills. The Silent Genomes Project has created an Indigenous Background Variation Library for improved rare disease diagnosis. Help us make it even better. tinyurl.com/bdh7d6bu Please repost

great job opportunity to work as a research associate on the Silent Genomes project! universityaffairs.ca/search-job/?...

Our job posting for 1 or more PDF positions in Vancouver Canada is now live here: tinyurl.com/4mrjw3m2 Please share/repost and apply soon!

Less than 2 weeks left to apply to join the Leena Peltonen School of Human Genetics 27-31 July in Hinxton, UK! If you are a PhD student in your last year or very recently defended your PhD, it's your place to be! lpshg.com

Join me! Online and in person (Cambridge MA) 10th Annual Rare Disease Day Event: An Era of Innovation for Rare Diseases Feb 25 afternoon broad.io/RDD2025

Have/nearly have a PhD? ≤7 years post-doc experience? Working outside UK? Not a UK citizen? BA & Royal Society offering 2-yr Fellowships for early career researchers to come to the UK! 💷 Includes: Research expenses £12k Relocation up to £8k 🗓️ Deadline: Mar 18, 2025 (17:00 GMT) #ResearchFunding

More archeological findings emerging from the lab cleanup #AcademicSky #AcademicChatter

📢 Abstract submission for BSI Oxford and @immunologyoxford.bsky.social 's #OIS25 Symposium closes NEXT WEEK (7 Feb) Don't miss your chance to take part in this celebration of the outstanding #immunology research happening across Oxford 💫 Submit your abstract here 👉 bit.ly/4elJmnG

We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics

New sunlight beats old sunlight! www.theguardian.com/world/2025/j...