FinnGen-based study by Nina Mars, Joni Turunen and colleagues demonstrates that polygenic risk scores can identify individuals at substantially increased risk of developing glaucoma and those whose disease is likely to progress more rapidly. Read more: www.helsinki.fi/en/news/gene...

A unique job opportunity to work on some of the most exciting genomic datasets in the world!

FinnGen-konsortioon kuuluvat tutkijat Oulun yliopistosta ovat tunnistaneet kymmeniä uusia geneettisiä riskitekijöitä lannerangan selkäydinkanavan ahtaumalle. Tutkimus auttaa ymmärtämään paremmin tätä yleistä selkäsairautta. Lue lisää @oulu.fi tiedotteesta: www.oulu.fi/fi/uutiset/s...

FinnGen-konsortioon kuuluvia tutkijoita Itä-Suomen yliopistosta on osallistunut kansainväliseen yhteistyötutkimukseen, jossa tunnistettiin yli 90 Alzheimerin taudin riskiin liittyvää geneettistä aluetta. Laaja meta-analyysi tuotti uutta ymmärrystä taudin biologiasta. 🔗 www.uef.fi/fi/artikkeli...

We are pleased to announce the release of FinnGen DF13 results! 🧬 While the number of participants remains unchanged, DF13 incorporates updated health register data, increasing the number of cases across most disease endpoints. Browsing & download instructions here: www.finngen.fi/en/access_re...

We’re looking for a Project Manager to join our FinnGen team in Helsinki! The role centers on financial management of a major international research collaboration project. If keeping complex projects financially on track are your thing, this might be for you! jobs.helsinki.fi/job/Helsinki...

Two inspiring days at the FinnGen meeting at Novartis, Cambridge! Partners shared latest insights from FinnGen data across diseases & advances in biobank-scale analyses. Just as important were discussions on the future, outlining the next phase of FinnGen. Many thanks to our hosts and participants!

Tutkimuksemme kärjet ovat Tulevaisuuden teknologiat, Oppivat ja muuntuvat yhteiskunnat, Yksilöllinen terveys ja Kestävä planeetta. www.helsinki.fi/fi/uutiset/y...

Large-scale FinnGen-based study by Reeve et al., just published in Nature Genetics, provides the most detailed genetic map of autoimmune hypothyroidism to date and reveals a surprising inverse relationship between hypothyroidism risk and skin cancer risk. www.broadinstitute.org/news/study-r...

Tiesitkö, että FinnGen-tutkimuksessa tuotettu genomitieto on palautettu takaisin näytteen toimittaneeseen biopankkiin? Veripalvelun biopankissa on pilotoitu tähän tietoon perustuen hemokromatoosin riskitiedon palauttamista biopankkiin kuuluville verenluovuttajille: www.veripalvelu.fi/verenluovutt...

The largest genetic study of anxiety disorders to date has identified 58 genetic variants associated with anxiety. The research, published in Nature Genetics, was based on data from >120,000 individuals with anxiety disorders, from various cohorts, including FinnGen. www.nature.com/articles/s41...

🌍 On #WorldCancerDay we recognise those in the BBMRI-ERIC community working to advance cancer research. 🔬 In our first post, we looked at EU projects. Let's turn the spotlight on the researchers & biobankers driving cancer innovation - The teams behind the data, discoveries & breakthroughs. 🧵 1/2

FinnGenin suomalaisten partnerien edustajat tapasivat eilen Biomedicumissa Helsingissä ja etäyhteyden välityksellä. Kiitos kaikille osallistujille aktiivisuudesta tutkimuksen seuraavan vaiheen suunnittelussa!

This week, Aarno Palotie and Mark Daly are visiting our Finnish partner organisations presenting what FinnGen has achieved and discussing how to develop it in the future. Great that the seminars, organised with help from the analysts that support FinnGen locally, have turned out to be popular!

We've been contributing to an international study identifying 13 genetic markers associated with infection with the Omicron variant of the coronavirus. The study, led by Statens Serum Institut, was recently published in Nature Genetics: 🔗 www.nature.com/articles/s41... 🔗 en.ssi.dk/news/news/20...

New preprint 👇 Does diagnostic misclassification in EHR-based psychiatry GWAS suppress genetic discovery? We use simulations and FinnGen data to expand the SuperControl framework and propose a new ML approach (PRISMA) to boost signal discovery. Led by Lisa Eick & Zhiyu Yang!

On behalf of all of us in FinnGen team, we wish you Happy Holidays and a wonderful New Year full of exciting scientific discoveries! Thank you for being part of the FinnGen community and for helping move this effort forward together. 🧬❄️

Kindly note that the URLs for our publicly available meta-analysis result browsers have been updated. The browsers are now accessible at: ➡️FinnGen + pan-UKBB meta-analysis results: public-metaresults-fg-ukbb.finngen.fi ➡️FinnGen-MVP-UKBB meta-analysis results: public-mvp-ukbb.finngen.fi

Autumn semester publication wrap-up! 📄 This autumn, FinnGen researchers contributed to a remarkable set of papers across human genetics, medicine, and methods; spanning @natgenet.nature.com, @natcomms.nature.com, Hypertension, @ajhgnews.bsky.social and more. Here’s a 🧵 highlighting these studies ⬇️

We are looking for a Software Developer to join our international team in Finland! With us, you will gain invaluable experience in high-impact software solutions that empower researchers to analyse and visualise extensive genomic and health data. Apply by 30 Jan: jobs.helsinki.fi/job/Helsinki...

Excited to share our new FinnGen single-nucleus multiome preprint! 🧬 We profiled ~10M PBMCs (snRNA-seq + snATAC-seq) from 1,108 Finnish donors to map how genetic variants drive complex disease through chromatin and gene regulation 🧵👇 🔗 Link: www.medrxiv.org/content/10.1...

Researchers from the University of Edinburgh carried out the largest genetic analysis of delirium to date, drawing on data from several study cohorts, including FinnGen. The results demonstrate that APOE contributes to delirium susceptibility independently of dementia. www.ed.ac.uk/news/study-f...

In a new study, @hheyne.bsky.social and her team identified a Finnish-enriched missense variant in the SCN5A gene that acts like a natural lifelong cardiac sodium channel blockade, decreasing the risk of cardiac arrhythmias while also having some negative effects. hpi.de/en/article/h...

Check out our new article in #Circulation on an astonishing genetic variant in the ion channel #SCN5A that enables us to learn about #cardiac-arrhythmia and their treatment with sodium channel blockers. @finngen.bsky.social www.ahajournals.org/doi/10.1161/... Congrats to @jwanner.bsky.social

Depression in young adulthood has a stronger hereditary component and is associated with a higher risk of suicide attempts than depression that begins later in life, according to a new study led by researchers @ki.se, including FinnGen as one of the study cohorts: news.ki.se/genes-may-pr...

We are proud to welcome Alnylam Pharmaceuticals as the 15th pharma company to join our public-private partnership! Alnylam brings world-leading expertise in RNAi therapeutics to the consortium, further enriching the scientific and translational potential of the study. www.finngen.fi/en/alnylam-b...

FinnGen-aineistoa hyödyntänyt LL Joel Räsäsen normaalipaineisen hydrokefalian eli NPH-taudin geneettistä taustaa käsittelevä väitöskirja tarkastetaan tänään Itä-Suomen yliopiston terveystieteiden tiedekunnassa Kuopion kampuksella. Tilaisuutta voi seurata myös verkossa: www.uef.fi/fi/artikkeli...

Comment🚨 Large biobank projects like #FinnGen help in uncovering genetic factors that influence cancer risk and outcomes, enhancing risk prediction & biomarker and drug target discovery. @finngen.bsky.social @dalygene.bsky.social @aoxing2.bsky.social#FinnGen 📖 👇

If you are in or around Turku tomorrow, don’t miss Prof. Mark Daly’s @biocityturku.bsky.social guest seminar highlighting the latest FinnGen discoveries! 📆21st Oct at 12:00-13:00, Presidentti auditorium, BioCity Title: FinnGen and the road ahead in human genetics 🔗 biocityturku.fi/events/bioci...

Day 4 at #ASHG2025 and the FinnGen team is still going strong! 💪🧬 Visit today’s FinnGen posters (see the thread) and swing by booth #147 for some Finnish candies and great conversation!

Excited (😁) to share a commentary on @finngen.bsky.social & cancer research, co-written with Mervi Aavikko & @dalygene.bsky.social!! (View-only full text -> rdcu.be/eLlJs)

So much great FinnGen science on display again today at #ASHG2025! Make sure to visit the posters listed here, and stop by at our booth (# 147) for some Finnish salmiakki!

Here’s a look at today’s FinnGen-related posters at #ASHG25, showcasing some of our research community's latest discoveries.

#ASHG2025 in Boston is off to a great start! The FinnGen team is ready and waiting for you at Booth #147! Come say hi, explore insights from one of the world’s largest genomics initiatives and grab a FinnGen canvas bag (and other goodies)!

Just in time for #ASHG2025, a new FinnGen public data release is live! This release features the first clinical laboratory value association results. Analyses cover 383 lab measurements (OMOPIDs) with data from ≥1,000 participants each. Access the results here: www.finngen.fi/en/access_re...

We’re getting ready for an exciting week at #ASHG2025 in Boston! Come meet the FinnGen team at booth 147 - we’ll be sharing updates and showcasing new public resources and tools. Plus, don’t miss the various presentations featuring FinnGen results across the program! www.finngen.fi/en/meet-finn...

💥 New preprint & our first RCT! 💥 Does an extremely high or low BMI polygenic score influence weight loss after a diet intervention? GENEROOS is a 6-month randomized diet vs. control trial testing if genetic predisposition to higher BMI affects weight loss in overweight adults

FinnGen is in the spotlight! In EP 204 of #TheGeneticsPodcast, Prof. @sripatti.bsky.social, director of @fimm-uh.bsky.social, discusses how FinnGen’s data are helping translate genetics into real-world clinical tools, such as polygenic risk scores & treatment prediction. 🎙️ pod.fo/e/328c49

This week, ~230 national and international FinnGen partner researchers came together in Helsinki for our annual F2F-meeting at Kalastajatorppa. The excellent scientific presentations and exchange of ideas will help shape the next phase of FinnGen and advance our scientific goals. Thank you!

Congratulations to the winners of the FinnGen Publication Prize 2025! 🎉 🏆 Jakob German (FIMM/UH) 🏆 Ville Salo (University of Oulu) This annual prize is announced during our F2F meeting, celebrating outstanding science from the past year. A big thank you to Scellex for sponsoring this year’s prize!

It's the FinnGen Helsinki F2F time of the year! Our Scientific Director Aarno Palotie just kicked off this year's meeting by warmly welcoming our international and local guests. The next two days will be all about exciting science, great discussions, and catching up with colleagues.

Our trisomy work is now online! 🚀 Got curious after reading our short PheWAS paper? 👀 Catch me 🌠 & my talk 🎤 this October at #ASHG25 in Boston! Yes, I am still endlessly curious about sex chromosome aneuploidies - whether it's somatic (X/Y loss) or germline (trisomies)!! 💘

📣Online now! 📄 #PheWAS of male and female sex chromosome trisomies in 1.5 million participants of MVP, FinnGen, and UK Biobank @finngen.bsky.social @ukbiobank.bsky.social

We are looking for a Data Scientist to support our clinically oriented research teams in generating insights from decades of rich, longitudinal health data. If you are inspired by the opportunity to contribute to cutting-edge research at a global scale, apply here: jobs.helsinki.fi/job/Helsinki...

📢 Another month, another set of impactful studies! Here are the papers published in July 2025 that utilized FinnGen data and credited us as a co-author. Exciting to see our resource advancing science across medical fields. Thread👇 #FinnGen #genetics

A new FinnGen-based study by researchers from Tampere University & @ki.se has identified genetic variants linked to brain function, immune defence and metabolism that contribute to the development of frailty in older people. #genomics #research news.ki.se/genes-reveal...

📢 Our newest batch of scientific publications! 📢 Here are the papers published during June 2025 that used FinnGen data and credited us as a co-author. Thread👇 #FinnGen #genetics

📢 A fresh batch of scientific discoveries! Here are the papers published in May 2025 that used FinnGen data and credited us as a co-author. Thread👇 #FinnGen #genetics

Suomalaisessa väestössä esiintyvä harvinainen TYROBP-geenimuutos lisää riskiä sairastua Alzheimerin tautiin, osoitti Itä-Suomen yliopiston johtama, FinnGeniä hyödyntänyt tutkimus. Geenimuutos vaikuttaa aivojen tulehdusta säätelevien mikrogliasolujen toimintaan. www.uef.fi/fi/artikkeli...

📢 Here comes a list of papers published in April 2025, where FinnGen has been utilized and listed as a co-author. Great to see our data driving such an impactful science! Thread👇 #FinnGen #genetics