“Towards modeling evolving longitudinal health trajectories with a transformer-based deep learning model” in collaboration with Pekka Marttinen at @AaltoUniversity www.sciencedirect.com/science/arti...

If you are interested in our pilot use of cross-EU health data ahead of the European Health Data Space implementation, check this out pubmed.ncbi.nlm.nih.gov/40926479/

A project many years in the process, we’re pleased to present our work on multi-ancestry meta-analysis across a boatload of traits in the UK Biobank: www.nature.com/articles/s41...

Cool work from @ewanbirney.bsky.social Moritz Gerstung, Tom Fitzgerald about modeling health trajectories with generative AI! www.nature.com/articles/s41...

Some people call it a minefield. Others call it dangerous, even irresponsible. I call it the most promising field in life sciences. My love letter to social science genetics: communities.springernature.com/posts/a-love...

Check out @tuomohartonen.bsky.social blog post on our study, out today in Nature Genetics, comparing electronic health record-based risk scores with genetic polygenic scores, and how they work better together! tuomohartonen.substack.com/p/medical-re...

Are electronic health records (EHR) more predictive of disease onset than polygenic scores? Can we transfer EHR-based prediction models between countries? Our study on these questions using 3 biobank-based studies with N>845K, is out in @natgenet.nature.com today: www.nature.com/articles/s41...

I wrote another book & I'm very excited (& nervous) for it to be released into the world: www.penguinrandomhouse.com/books/714593...

Happy to see this online! Having an extra sex chromosome really challenge the binary definition of sex based on XX and XY. So it is not only a medical, but also an important societal question.

Impressive paper by EPIC. They built a autoregressive transformer on 150M individuals and 115 billion medical events. Including: diagnoses, medications, lab values, procedure Cons: model is not shared (and unlikely will be) arxiv.org/pdf/2508.12104

Papers of the months in Health Data Science healthdatascience.substack.com/p/monthly-up...

The iPSYCH study represents a unique example to understand the ethical and legal challenges of using existing samples/data for health research. A thread 🧵 www.science.org/content/arti...

Dived into past, present & future of human genetics with brilliant students & mentors.Grateful for the chance to present my work on personalized sequence→expression prediction and discussions with @sashagusevposts.bsky.social @bpasaniuc.bsky.social @mashaals.bsky.social @tuuliel.bsky.social & others

This was such a special event! So grateful that I could be part of it, learning about great science, making truly unique connections with amazing fellow students and tutors, and even learning how to punt 🛶 Huge thanks to everyone who helped bring this unique school back to life!

It was a pleasure to be part of this summer school. Students were amazing, it was a great experience getting the chance to discuss one on one without hierarchy for three days with them. They taught me so much.

Truly grateful for the exceptional opportunity to participate in #LPSHG2025 last week, featuring a stellar ✨ lineup of leading researchers who doubled as tutors, alongside inspiring fellow PhD students. Excited to apply my learnings and see where this collaborative spirit takes genomics next!

Great meeting! Renewed excitement about all the cool research happening in genetics right now 🧬

The pace and breadth of discovery are mind-blowing and made even better by the cool people involved. So grateful to have taken part in this event 🙏 Now to process it and try to apply a tiny fraction to new research projects

Leena Peltonen School of Human Genetics in full-swing! @gosiatrynka.bsky.social @dgmacarthur.bsky.social @bpasaniuc.bsky.social @tuuliel.bsky.social @hilarycmartin.bsky.social @sashagusevposts.bsky.social @zkutalik.bsky.social @mashaals.bsky.social @alemedinarivera.bsky.social

🇪🇺 The European Commission R&D website has highlighted our ERC-funded work on AI for health data. This is a part of a larger effort to highlight how EU-funded AI research has enabled innovation and discoveries in life sciences. cordis.europa.eu/article/id/4...

Can we use genetics to make real-world evidence more like randomized trials and improve trial design in the process? In our latest paper, we emulate 4 cardiometabolic RCTs in FinnGen and test how polygenic scores can improve trial emulation rdcu.be/eryti

Ely Lilly buys Verve therapeutics www.investors.com/news/technol...

New preprint: One of the largest studies (N = 67,000) on how sexual desire varies with age, sexual orientation, education, job, number of children, recent birth, and relationship satisfaction, and how the trends differ by gender. doi.org/10.21203/rs....

The FIMM Young Investigator for April 2025 is Feiyi Yang, a doctoral researcher supervised by @andganna.bsky.social & Tiinamaija Tuomi. Warm congratulations to her for her recent 1st-author publication on the effects of parental autoimmune diseases on type 1 diabetes in offspring in Cell Genomics!

If you are seriously considering an academic career in Europe, and you are weather hardened by the mid-west or north east, this is an amazing opportunity!

We have 2-3 group leader positions opening @fimm-uh.bsky.social !! We are looking for outstanding candidates in human genetics and precision medicine. This time we have a focus on population health data science. E.g. AI for EHR/health data        Generous starting package 💰 shorturl.at/FAk6n

Matteo Ferro, a doctoral candidate in my team has a new blog on health data science where he is collecting the most interesting papers, each month. Check it out!                healthdatascience.substack.com

It's #eshg2025 #eshg25 time 🥳 Here is where you can catch the team over the next few days. Please go and say hi!

Did you know that some genetic males have plasma proteomes similar to those of genetic females and vice versa? What are the consequences of this? Come discuss with me at our poster number P18.021.D on Monday 26.5. at 4pm-5pm at #ESHG2025

Personalized growth curves using results from longitudinal height GWAS of 80k japanese children

🎉 Hi #ESHG2025, the Statistical Genetics Group and alumni (@zkutalik.bsky.social) is coming in force!
 Check out our latest work on human genetics! 
📍Come see our talks & posters, or reach out to meet us!

Our team presentations at #eshg25 #eshg2025. looking forward!!

Behavioral and cognitive sciences got 30% funding boost despite very large cuts anywhere else. Interesting. Does anyone know why? the other increase in funding is in area related to national security, which makes sense given the gov.

We are looking for a post-doc/research fellow working on non-bullshit, reality-centered AI. Meaning: unique nationwide EHR and -omics with the possibility to recontact people and prospectively test multimodal AI approaches. jobs.helsinki.fi/job/Helsinki... @FIMM_UH @FinnGen_FI

Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...

Join us to listen to and meet Andrea in Lausanne 18-19 September. Register and submit an abstract if you feel like sharing your work! cbiosymposium.unil.ch

New exciting results from Marea therapeutics and Novartis www.thelancet.com/journals/lan...

One of the excellent doctoral thesis @helsinki.fi in 2024 awards goes to @bordinki.bsky.social! Mattia’s thesis "Leveraging large-scale biobanks for genetic discovery and better public health" was supervised by @andganna.bsky.social & @sripatti.bsky.social. Congrats! www.helsinki.fi/en/news/univ...

NIH to suspend funds for research abroad as it overhauls policy - An exclusive story from the Nature News team This NIH move threatens thousands of collaborative projects on infectious diseases, cancer and more 🧪 #AcademicSky #MedSky @nature.com www.nature.com/articles/d41...

New pre-print klaxon: "Discovery and characterisation of gene by environment and epistatic genetic effects in a vertebrate model" led by the excellent Bettina Welz + @saulpierotti.bsky.social from @wittbrodtlab.bsky.social, Felix Loosli, Kiyoshi Naruse and my own lab www.biorxiv.org/content/10.1...

🚨 EBI has just lunched a new portal to calculate genetic scores from individual-level genetic data. Check it out 👇. It is very cool! geneticscores.org It is linked with the @pgscatalog.bsky.social This was supported by INTERVENE

Effects of parental autoimmune diseases on type 1 diabetes in offspring can be partially explained by HLA and non-HLA polymorphisms www.cell.com/cell-genomic... @andganna.bsky.social

Why do children with Type 1 Diabetes (T1D) often have parents with autoimmune diseases? Our new study shows parental autoimmune conditions affect offspring’s T1D risk through complex genetic factors, including both HLA and non-HLA variants. 🔗 www.cell.com/cell-genomic...

Wonderful collab on predicting weight loss after GLP1-RA and bariatric surgery. We found a small effect for bariatric surgery! More data needed for follow-up work!

A large international study from Jakob German, @andganna.bsky.social et al. published in Nature Medicine shows that genetic factors have a limited impact on the effectiveness of 2 widely used weight-loss interventions, GLP-1 receptor agonists and bariatric surgery. 🔗 www.nature.com/articles/s41...

🚨 New paper 🚨 Do known genetic factors for obesity and type 2 diabetes affect weight loss from GLP1-RA (Ozempic) or bariatric surgery? 🔍 10,960 people, 9 biobanks, 6 countries 🧬 Minimal genetic impact on GLP1-RA response 📉 Modest effect after surgery www.nature.com/articles/s41...

After UK, Denmark announces a national gateway to access health data novonordiskfonden.dk/en/news/new-...

Chuffed that this is finally out in the wild!! The preprint was posted in September 2023, so the original thread is buried in the dark depths of Twitter. Instead, see sparkly new thread👇 from super 🌟 postdoc Alex (@alextremophile.bsky.social) who drove this work 👏

UK launches a national health data service agency wellcome.org/news/nationa...