Masahiro Kanai
@masakanai.bsky.social
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Instructor in Medicine, MGH / HMS / Broad Institute
https://mkanai.github.io/
Excited to share our new FinnGen single-nucleus multiome preprint! 🧬 We profiled ~10M PBMCs (snRNA-seq + snATAC-seq) from 1,108 Finnish donors to map how genetic variants drive complex disease through chromatin and gene regulation 🧵👇 🔗 Link:
www.medrxiv.org/content/10.1...
2 days ago
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Masahiro Kanai
Konrad
3 months ago
A project many years in the process, we’re pleased to present our work on multi-ancestry meta-analysis across a boatload of traits in the UK Biobank:
www.nature.com/articles/s41...
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Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects - Nature Genetics
Genome-wide analyses for 7,266 traits leveraging data from several genetic ancestry groups in UK Biobank identify new associations and enhance resources for interpreting risk variants across diverse p...
https://www.nature.com/articles/s41588-025-02335-7
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