We have something for everyone- CSF flow & #neurodegeneration, ciliary trafficking of PKD2 complexes, cilia & #actin dynamics, #DNADamageResponse & multiciliation, cilia & pituitary development & transcriptional control of ciliogenesis... Great breaking science & rising talent to be showcased...🧪

Thrilled to see our study on how kinesin-2 motors are switched on and off published in @natsmb.nature.com ⚛️ ➡️ www.nature.com/articles/s41... Congrats to all authors from me and Anthony 🎉 @dunnschool.bsky.social Check out this animation made by talented PhD student @matthew-batisio.bsky.social 😆

Save the date! March 2027 on beautiful lake Maggiore right outside #Milan, are you ready for #Cilia2027? 🥳 Stay tuned for more info!

🎉Excited to see my master’s work contributed to this amazing paper! 🎥 🧠 Congrats to all co-authors 👏 Grateful for my time in Dr. Isabelle Caillé & Pr. Alain Trembleau’s lab #IBPS. Isabelle’s passion for science will keep inspiring me ✨ doi.org/10.1126/scia...

#Trypanosoma, fixed, expanded, and imaged with #STED, stained for tubulin. Scale bar refers to expanded specimen, original structures are 3-3x smaller. Image courtesy: @mbonhivers.bsky.social, MFP, CNRS, Univ. Bordeaux, France #fluorescencefriday #ExM #STEDmicroscopy

New interesting paper on MAPKBP1, which sheds new light on its localization and function at #cilia! Many thanks to Ria and Jan for inviting us to participate in this exciting work! Congratulations to all collaborators! #ciliopathies #kidney #nephronophthisis www.kireports.org/article/S246...

Daniel's paper is now published in @jcellsci.bsky.social, great experience with @reviewcommons.org 😀 Want to know everything tubulin assembly in trypanosome flagella and other microtubules? Here is the link: journals.biologists.com/jcs/article/...

Ciliated teddy bear!

Our last paper is now available on the Kidney International website! Thanks to all collaborators and special congrats to Alice and Guillaume... #cilia #ciliopathies #kidney www.sciencedirect.com/science/arti...

📣 Don’t miss the review by @bolettalab.bsky.social & S. Clerici on metabolic and mitochondrial alterations in #PolycysticKidneyDisease and other renal #ciliopathies ➡️ doi.org/10.1038/s443... at IRCCS San Raffaele Scientific Institute

IFT trains in primary #cilia Intraflagellar transport trains can switch rails and move along multiple microtubules in intact primary cilia | PNAS www.pnas.org/doi/10.1073/...

9 PhD positions to work on #cilia and #ciliopathies including 2 in our lab @hkd-l.bsky.social @institutimagine.bsky.social www.cilia-ai.eu

Dear cilia researchers, join us in the heart of the beautiful Vosges mountains to share your latest findings! This year, partnership with @for5547.bsky.social and keynote lectures by @micromotility.bsky.social and @mick-lab.bsky.social Registration is now open www.cfc2025.conferences-pasteur.org

📣Thrilled to announce that the registration for the 8th annual Czech #Cilia #Meeting (17 June 2025, #Brno) is NOW OPEN: 🪧https://forms.gle/wkooViZtBGxvVASNA 👩‍🔬INVITED SPEAKER: Ruxandra Bachmann-Gagescu ⏱️Registration deadline: 17 May 2025

First announcement for the 2025 meeting of the #cilia, #flagella and #centrosome club which will be held from October 13 to 15, in Oberbronn, Alsace, eastern France. gmgm.unistra.fr/en/news/meet...

First announcement for the 2025 meeting of the #cilia, #flagella and #centrosome club which will be held from October 13 to 15, in Oberbronn, Alsace, eastern France. gmgm.unistra.fr/en/news/meet...

Here is a recent paper by colleagues from @hopitalnecker.bsky.social and @institutimagine.bsky.social showing that loss of IFT27 lead to fetal #ciliopathies with #cilia defects in #kidney www.nature.com/articles/s41...

Interesting preprint by the group of Hervé le Hir showing that inhibition of the Exon Junction Complex (EJC) which is found at the basal body perturbed primary #cilia biogenesis in neural stem cells. www.biorxiv.org/content/10.1...

New great paper in Developemental Cell by Nathalie Delgehyr and collaborators in Nathalie Spassky's lab on the action of actin-based cytoskeleton on the the nucleus in multiciliated cell differentiation. #cilia www.sciencedirect.com/science/arti...

Two recent great papers in Cell Reports from Alice Meunier on how cell cycle regulates #cilia biogenesis and multiciliated cell differentiation.

Last few days to submit your research on #cilia and #flagella to our upcoming special issue, coordinated by Guest Editors Pleasantine Mill @cilialab.bsky.social and Lotte Pedersen @lottepedersen.bsky.social. journals.biologists.com/jcs/pages/ci...

March #ImageOfTheMonth goes to M.Bonhivers from MFP lab (UMR 5234). Trypanosoma brucei cell was extracted in detergent, expanded 4.2 fold using U-ExM, labelled for the microtubule cytoskeleton (magenta) and for the Hook Complex (yellow), and images usinf scanning confocal microscopy.

www.nature.com/articles/s43... Happy and proud to have participated in this superb study about primary cilia and autophagy in neurons! congrats to @manonrivagorda.bsky.social & everyone in Oury lab @inem-necker.bsky.social

Thrilled to announce that my PhD work is finally out in the @embojournal.org ! In this paper, we show that Alms1 proteins are required for the amplification of the Plk4-Ana2 pool at the centriole duplication site using #U-ExM on various Drosophila tissues, including testis, brains, and embryos.

Join us: 1️⃣ 4️⃣ fully-funded PhD studentships in top labs across Europe (inc. with us in Edinburgh 🇬🇧 ) for Cilia-AI! #RareDisease #Cilia #Imaging #Genomics #AdvancedImaging #DiseaseModels #DiseaseMechanisms #Therapeutics #Proteomics #AI CLOSES: MARCH 16th 2025! www.cilialab.co.uk/cilia_ai-phd...

Pour Paris, départ à 13H30 de Jussieu!

Last from the archives, scanning #electronmicroscopy pictures of #cilia in #kidney IMCD3 cells (no triton) by Rania and Thierry from @bastinlab.bsky.social. The longest straight cilium ever and two interacting ones!

Explicit content… demembraned n.k.d #cilia !!! Other examples of scanning #electronmicroscopy of triton-treated IMCD3 #kidney cells with @bastinlab.bsky.social - see also previous post.

In 2009, Rania Ghossoub in my lab and Thierry Blisnick in @bastinlab.bsky.social decided to apply a protocol used in Trypanosoma to remove membranes and have access to the axoneme, here is what they saw in IMCD3… #cilia

🤩 yes Philippe, great period around our ciliary pocket story! Some other pictures coming soon where other details can be seen…

“Join the Pigino Lab! We’re hiring a PhD student to explore primary cilia biology using advanced imaging, spatial ‘omics, and AI. Apply now at www.cilia-ai.eu and be part of the Cilia-AI Doctoral Network!”

Welcome to the PKD Foundation’s Bluesky! We’re proud to be the only organization in the U.S. solely dedicated to finding treatments and a cure for polycystic kidney disease (PKD). Learn more about our organization at pkdcure.org.

Excited to announce the 10th "Choanoflagellates & Friends Workshop" over May 20-22 in our own Institut Pasteur in Paris: 2025choanocon.wordpress.com Registrations open til March 15, abstract til March 5. Pre-conference event for students/postdocs on 19/05. Plenty of slots for selected talks/posters!

Ok, let's start this thing here with my favorite 3D animation connected to our recent paper on structure and interactions of beta cell primary cilia. www.nature.com/articles/s41... Still super ecited about cilia-axon contacts in the pancreas.

Recent interesting paper on cilia signaling in pancreatic beta-cells. Together with the last one from @nachury.bsky.social lab (see previous post), fascinating examples of complex regulation of GPCR/cAMP signaling in cilia. www.embopress.org/doi/full/10....

New paper! journals.plos.org/plosbiology/... Postdoc extraordinaire @ireneon.bsky.social got to the bottom of a particularly vexing conundrum: The GPCR melanocortin receptor 4 (MC4R) is barely detectable in cilia, yet its localization to cilia is absolutely critical to body weight homeostasis.

🔔 Dernier rappel ! 🔔 Il ne vous reste plus beaucoup de temps pour répondre à l’enquête du Collège sur le financement de la recherche. Votre avis est essentiel ! 📌 Participez ici 👉 societes savantes.limesurvey.net/121783 Merci pour votre contribution ! 💡🔬

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We propose a model where the new flagellum grows in a linear manner while the old one is locked but shrinks slightly, hence requiring unlocking and compensation after cell division, leading to such multicoloured flagella following induction/deinduction/reinduction of tagged tubulin 😉

We invite you to submit your latest research to our special issue - Cilia and Flagella: from Basic Biology to Disease. This issue will be coordinated by two Guest Editors: Pleasantine Mill @cilialab.bsky.social and Lotte Pedersen @lottepedersen.bsky.social. journals.biologists.com/jcs/pages/ci...

First announcement for the next CFC meeting which will be organized by Séverine Bär, Sylvie Friant and Hélène Dollfus with colleagues from the #cilia and #centrosome workgroup of the German Society for Cell Biology. It will take place from October 13th to 15th 2025 in Oberbronn near Strasbourg.

Our last mini-symposium was last week at Imagine Institute!