Our latest paper on protein expression and mRNA stability is out! academic.oup.com/nar/article/... Check out how to increase your protein output with a simple trick. Congratulations to first author @Anna Lipońska, it was a great collaboration with the Aalberts group. #RNAsky #ribosome #EGM

🫳 Metastable folding of Bacillus subtilis glmS ribozyme modulates turnover by RNase J1: www.sciencedirect.com/science/arti... #subtiwiki

In this study, we highlight the importance of the base composition of the first codons for protein expression. An increased abundance of adenine (A) and a decrease in guanine (G) enhance expression and improve mRNA stability. The mediator of this effect is the ribosome.

Are authors fairly judged by assessing the #journals in which their work is published? @bihutchins.bsky.social &co reveal that most influential papers are published in lower tier journals, and more authors would be better recognized with #ArticleLevelMetrics #ALMs @plosbiology.org 🧪 plos.io/4oV58Ed

DusB links tRNA modification with oxydative stress response in V. cholerae! Congrats to @zeynepbaharoglu.bsky.social and colleagues!

RNA–RNA interactome approaches provide in vivo evidence for a critical role of the Hfq rim face in sRNA–mRNA pairing url: academic.oup.com/nar/article/...

An rRNA modification to adapt translation to anaerobic conditions!

The EMBO Gold Medal 2025 was awarded to Tanmay Bharat and David Bikard: https://www.embo.org/press-releases/embo-gold-medal-2025-awarded-to-tanmay-bharat-and-david-bikard/ 🧪 At #CellBio2025, the EMBO Gold Medal was handed over to David Bikard in recognition of his pioneering work on #GeneEditing.

Exametabolomics!

Today, Minister-President Markus Söder awarded @jorg-vogel-lab.bsky.social the Bavarian Maximilian Order. Presented every two years, the award recognizes outstanding accomplishments in science & the arts and is regarded as one of the state’s highest honors. Congrats on the “Bavarian Nobel Prize”! 👏🎉

Very cool paper, studying mechanisms (and a toxin) targeting the ribosome, translation initiation and the use of Shine-Dalgarno motifs!

BREAKING: Friday night massacre underway at CDC. Doznes of "disease detectives," high-level scientists, entire Washington staff and editors of the MMWR (Morbidity and Mortality Weekly Report) have all been RIFed and received the following notice:

Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here: emploi.cnrs.fr/Offres/Docto...

Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.

hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!

Communiqué de presse : financement de la recherche publique : la communauté scientifique alerte sur un système à bout de souffle. #veilleESR, @info.gouv.fr @agencerecherche.bsky.social @cnrs.fr @franceuniversites.bsky.social @inserm.fr @inrae-france.bsky.social @enseignementsup-recherche.gouv.fr

Congrats to @mlejars.bsky.social for this really cool publication! Tired of your somewhat easy life doing genetics in E.coli? Make it even way easier with Maxence's method!!

So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!

Exciting FULL PROFESSORSHIP at the Vienna BioCenter - Molecular Mechanisms of Disease Mechanisms: www.maxperutzlabs.ac.at/news/open-po... Come be our colleague!

Many congrats to Ninon Christol from our Microbial Gene Expression research unit, IBPC CNRS, as well as to @maximiliankohl.bsky.social from IBMC at Univ. Strasbourg, for their amazing poster prizes!

Happy to have presented my work at the #microbialRNAs meeting today, with a very active discussion and a beautiful session! Looking forward to more science in the next few days in Strasbourg.

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!

🚨 New Preprint Alert 🚨 Our latest work, A Zur-dependent regulatory RNA involved in maintaining zinc homeostasis in Staphylococcus aureus, is now live on bioRxiv! 🧬🦠📄 Check it out here: www.biorxiv.org/content/10.1...

Beautiful paper on translation start sites and extented SD motifs in Staph. aureus. www.biorxiv.org/content/10.1... Congrats to colleagues in Strasburg univ.!

What a fantastic achievement! Carine Tisné is rewarded the CNRS Silver medal for her structural studies of tRNA modification. We are very proud of her, at the Microbial Gene Expression research department, IBPC! www.insb.cnrs.fr/fr/personne/...

Check this out : the mechanism of Rae1 cleavage upstream of stalled ribosomes in B.subtilis!

Marie Curie fellowship, post-doc hosting oppotunity in my lab. MSCA Post-doctoral Fellowship at IBPC Paris on RNA modifications in bacteria (FRANCE) 🦠💫 euraxess.ec.europa.eu/jobs/hosting...

This is a devastating outcome for those who have spent their careers trying to stop HIV/AIDS and for all the activists who demanded the world take this work seriously.

Ribosomes modulate transcriptome abundance via generalized frameshift and out-of-frame mRNA decay

Groundbreaking?

New paper from the lab! Want to know if there is a difference in ribosome collisions between your samples? We show that you can detect this in the rRNA reads in your ribosome profiling data. academic.oup.com/nargab/artic...

Swarm-seq Reveals Functional Divergence in CsrA Homologs Across Bacteria. https://www.biorxiv.org/content/10.1101/2025.05.05.652322v1

Bonjour, un poste d´IE (biochimie/BM) en mobilité interne (NOEMI) est disponible au Laboratoire de Biologie Structurale de la Cellule (bioc.ip-paris.fr), École polytechnique, Palaiseau. Rejoignez-nous!!! emploi.cnrs.fr/Offres/MOBIN... Merci de faire circuler l´information!

🧬🧫🦠 @science.org Bacterial reverse transcriptase synthesizes long poly-A–rich cDNA for antiphage defense | Science www.science.org/doi/10.1126/... #microbiology #bacteriophage #antiphage #immunity #DNA #RNAsky #RT #Cryo-EM #DRT9

I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Non-model Bioeng Custom Lab Hardware Turn Key Genetic Design Please repost for reach 💚

My dept in London at Imperial (Bioengineering) is recruiting a group leader at Professor level 🧑‍🎓 Please RT. It's a great place with world-class expertise in all sorts of biomedical & biological engineering topics like synthetic biology. It's also not in the USA. www.imperial.ac.uk/jobs/search-...

Compartments made of RNA-CsrA 😯

Cool work from the @jonathandworkin.bsky.social lab : new riboswitch-based in vivo (p)ppGpp reporter systems for Bacillus subtilis!

Latest work from the lab - we identify a translation factor, YebC2, that reduces ribosome stalling in B. subtilis! Congrats to co-first authors: grad students Hye-Rim Hong & Cassidy Prince & undergrad Dennis Wu @denniswu02.bsky.social journals.plos.org/plosgenetics...

RiboSeq during branched chained amino acid resistance!

Some say, important sRNAs can be recognized by having their own “sponge” 🧽. Well, here comes InvS: a sponge of PinT (and vice versa). Congrats to @kooshapour.bsky.social and @ginlaca.bsky.social on their great work! doi.org/10.1101/2025...

Streptomycin targets tumor cells via an impact on ROS production www.sciencedirect.com/science/arti...

A new RIL-seq experiment, now to study host-pathigen interactions! Congrats to the @westermannlab.bsky.social and colleagues!

I am glad to share our detailed super resolution imaging protocol for single particle tracking in human cell. doi.org/10.1101/2025...

I am thrilled to share this new preprint from our lab! We find (>800!) 30S binding sites in hundreds of 5'UTRs, but also new dynamic steps of translation initiation. www.biorxiv.org/content/10.1... Congrats to all co-authors at the RNA control of gene expression lab, IBPC CNRS (Thread, 1/6)

Thrilled to see our story now out at @naturecomms.bsky.social A shared adventure with Estelle Leroy and Mathieu Rougemaille @i2bcparissaclay.bsky.social, and with the precious help of the @palancadelab.bsky.social Such a tiny RNA with such a wide range of functions www.nature.com/articles/s41...

Job alert ! I am looking for a postdoc to work on "computational investigation of ion-effects in ribozyme catalysis" to work with me in Paris (France). 1-year contract funded by @agencerecherche.bsky.social, with possible 2nd year in collab. with P. Jungwirth @iocbprague.bsky.social #compchem #RNA

Make your E. co-lives easier with @mlejars.bsky.social gene editing toolkit! Everything to build your reporter fusions, recombinant proteins and more!

Here we unexpectedly find that the ribosomal protein S20/L26—identified at the dawn of ribosome research but later deemed a biochemical artifact—is indeed a genuine component of the large ribosomal subunit. More on this ribosome content variation is here: www.nature.com/articles/s41...

If anyone is looking for a lab technician/manager with nucleic acid isolation, library prep, and sequencing analysis experience preferably in the DMV, my former biologist is looking for a job. She was unfortunately terminated in Feb as part of the probationary employee firings. DM me for her info