Two M. tuberculosis RelE toxins don’t cut mRNA, they slice 16S rRNA itself, shutting down translation in a totally unexpected way, new study reveals. A big leap in understanding TB’s survival tricks and new angles for therapies. 📖 shorturl.at/Z8MVX ✍️ @genevauxpierre.bsky.social & coll. #MicroSky

I am thrilled to share this new preprint from our lab! We find (>800!) 30S binding sites in hundreds of 5'UTRs, but also new dynamic steps of translation initiation. www.biorxiv.org/content/10.1... Congrats to all co-authors at the RNA control of gene expression lab, IBPC CNRS (Thread, 1/6)

🚨 New Preprint Alert 🚨 Our latest work, A Zur-dependent regulatory RNA involved in maintaining zinc homeostasis in Staphylococcus aureus, is now live on bioRxiv! 🧬🦠📄 Check it out here: www.biorxiv.org/content/10.1...

Exciting new paper from Wonsik Lee's group in Korea, using TnSeq to study gene essentiality in various intracellular and extracellular infection niches of S aureus. Loads of cool insights into metabolism and nutrient acquisition in the host www.nature.com/articles/s41...