David Lalaouna
@davidlalaouna.bsky.social
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Nutritional immunity and regulatory RNAs CNRS/University of Strasbourg
The iron-regulated small regulatory RNA IsrR modulates expression of genes utilized for dioxygen metabolism and heme synthesis in Staphylococcus aureus | mBio
journals.asm.org/doi/10.1128/...
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The iron-regulated small regulatory RNA IsrR modulates expression of genes utilized for dioxygen metabolism and heme synthesis in Staphylococcus aureus | mBio
Staphylococcus aureus causes numerous and varied infections in mammals, making it a significant public health burden and concern. The prevalence of S. aureus infections is due to its robust repertoire...
https://journals.asm.org/doi/10.1128/mbio.01415-25
4 months ago
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reposted by
David Lalaouna
Westermann Lab
5 months ago
New preprint from the lab, in collaboration with Wenhan Zhu (U Vanderbilt): using dual RNA-seq during B. theta colonization of the host mucous layer, we identify IroR--an iron-response sRNA that tunes capsule expression and facilitates adaptation to iron limitation.
doi.org/10.1101/2025.09.08.672848
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An RNA regulates iron homeostasis and host mucus colonization in Bacteroides thetaiotaomicron
Symbiotic bacteria in the human intestinal microbiota provide many pivotal functions to human health and occupy distinct biogeographic niches within the gut. Yet the molecular basis underlying niche-s...
https://doi.org/10.1101/2025.09.08.672848
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reposted by
David Lalaouna
Andreas Peschel
6 months ago
"What makes S. aureus such a difficult vaccination candidate?" Here are some answers:
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🚨 New Preprint Alert 🚨 Our latest work, A Zur-dependent regulatory RNA involved in maintaining zinc homeostasis in Staphylococcus aureus, is now live on bioRxiv! 🧬🦠📄 Check it out here:
www.biorxiv.org/content/10.1...
6 months ago
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reposted by
David Lalaouna
8 months ago
New review out in
@narjournal.bsky.social
! 🔎 What makes a small RNA work? We discuss: 🧬 Sequence features 🤝 Hfq, ProQ & RNA chaperones ✂️ RNase E & degradosome interactions 🧪 Lessons for RNA design 📖 Read:
academic.oup.com/nar/article-...
@unswbabs.bsky.social
@davidlalaouna.bsky.social
@Jai Tree
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What makes a small RNA work?
Abstract. Bacterial small RNAs (sRNAs) are key regulators of gene expression, interacting with target messenger RNAs (mRNAs) through imperfect base pairing
https://academic.oup.com/nar/article-abstract/doi/10.1093/nar/gkaf563/8171871?utm_source=advanceaccess&utm_campaign=nar&utm_medium=email
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David Lalaouna
La Recherche
11 months ago
Suite aux mesures de Donald
#Trump
concernant la recherche scientifique,
#StandUpforScience
aura lieu vendredi aux États-Unis. En France, des scientifiques se joignent au mouvement. Entretien avec Olivier Berné, dir. de recherche et co-organisateur de SUfS France
www.larecherche.fr/politique-po...
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“Mes collègues aux Etats-Unis me disent qu'ils ont peur”, entretien avec Olivier Berné
Suite à l’élection de Donald Trump et à ses mesures concernant la recherche scientifique, la mobilisation Stand Up for Science aura lieu vendredi 7 mars aux États-Unis.
https://www.larecherche.fr/politique-politique-de-la-recherche/%E2%80%9Cmes-coll%C3%A8gues-aux-etats-unis-me-disent-quils-ont-peur%E2%80%9D-entretien-avec-olivier-bern%C3%A9
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reposted by
David Lalaouna
Benjamin Ezraty
11 months ago
Poste d’ingénieur(e) de recherche CNRS – 18 mois – Marseille Rejoignez notre équipe sur un projet de prématuration du CNRS ! Nous recherchons un(e) ingénieur(e) de recherche spécialisé(e) en microbiologie, biologie moléculaire et en microscopie. 🫵 🔬👨🔬👩🔬
emploi.cnrs.fr/Offres/CDD/U...
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reposted by
David Lalaouna
Ákos T Kovács
12 months ago
Biofilms in Bacterial Pathogenicity👇🏼 with Nicola
@bacteriacities.bsky.social
(cool story on Bacillus subtilis biofilm colonies and competitiveness within) and Jean-Marc
@jmghigolab.bsky.social
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reposted by
David Lalaouna
Rebecca Keogh
about 1 year ago
Applications are open for the 2025 GRS/GRC on Staphylococcal Diseases! Make sure to get your abstracts submitted for the potential to present your work in beautiful Barcelona!
www.grc.org/staphylococc...
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reposted by
David Lalaouna
Kevin Waldron
about 1 year ago
One more week to get your applications submitted
add a skeleton here at some point
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reposted by
David Lalaouna
Kevin Waldron
about 1 year ago
Looking for a postdoc position? Want to apply your biochemistry skills to answer interesting evolutionary questions of how metalloenzymes evolve? Join my growing team in Warsaw at @IBBPAS. We're seeking a talented new postdoc to work on the superoxide dismutases.
ibb.edu.pl/app/uploads/...
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reposted by
David Lalaouna
Ewan Harrison
about 1 year ago
Our paper investigating the mutational landscape during Staphylococcus aureus during colonisation is out now
rdcu.be//d55l3
@fcic.bsky.social
@sangerinstitute.bsky.social
@ibv-csic.bsky.social
University of Cambridge
@julianparkhill.bsky.social
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The mutational landscape of Staphylococcus aureus during colonisation
Nature Communications - The authors applied a genomic and evolutionary approach to study Staphylococcus aureus in host adaptation during colonisation revealing signals of adaption in metabolic...
http://rdcu.be//d55l3
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