From Robert Reich's "A warning about American fascism", a PSA made by the US government in 1945...Happy 250th for all, except those stoking hate against our country. www.youtube.com/watch?v=MnA1...

If this rule change goes forward, science in the US “will stop,” says Colette Delawalla, the founder and CEO of Stand Up for Science. “It won’t exist anymore.” Read the article here:zurl.co/gEtBL Then help us take action against the proposed rule here: zurl.co/J3Z23

Help Stop Trump’s Project 2025 Scheme to Kill Science: Today's #BradCast Guest: @cdelawalla.bsky.social of @standupforscience.net; Also: Judge nixes Trump election rigging order; Mamdani's progressives sweep; Primary results from UT, MD, SC, NY... FULL STORY, LISTEN: bradblog.com?p=17804

Francis Crick was born OTD in 1916. We've all seen the DNA diagram that appeared in Crick and Watson’s Nature paper (left), but have you seen his sketch (right), from which his wife Odile made the published version? 🌱🐋🧪🐡 #EvoBio #HistSTM

If you have ever emailed a writer to let them know you enjoyed something they wrote, you are among the noblest and best and most saintly in this entire world, and I hope you sleep really well tonight.

As it turns out: electrified tracks end in DC, so we'll switch to a diesel engine, allowing riders to reflect on what progress looks like, backwards.

Thank you #NobelLaureate Jack Szostak for sharing these thoughts, which many US scientists and physicians resonate with newsletter.ofthebrave.org/p/im-a-nobel...

Look at the women at NASA. They are the ones pushing the boundaries of science, solving problems most people can’t even understand, and carrying this country forward, while our politicians right now posture and stumble through talking points. And they are doing it all with joy.👇

"A well-articulated argument against a new data center in Ohio" (1/2) Source (video not split here): old.reddit.com/r/interestin...

So very very proud of my dear friend Greg Hannon, a leader and intellectual powerhouse

Way to go Angela, Kristian and Gigi…great effort to empower truth over ideology

Republican AZ State Supe wants me off his damn lawn. Tough break: beginning April 24, I have 16 uninterrupted months on sabbatical to analyze his program’s data and make it public. Taxpayers deserve to see what they’re paying for. Mazel tov.

Happy St. Patrick's Day, New York.

🧵 Arizona Ed said it analyzed a random sample of 3K ESA transactions & concluded 1.9% of ESA $ unallowable. TLDR: 🫠They did not draw a random sample 🫠Either ADE lied or made a very basic error 🫠Focusing on unallowed misses big picture; too many low-ROI for human capital items are allowed 1/10

Princeton's @jenjennings.bsky.social research takedown of AZ Dept Ed: stunning & seeming willful abuses of their voucher program. Hope the AZ Attorney General makes all accountable for > $400M in stockpiled/misused voucher money. And hats off to AZ 12News for pursuing! www.12news.com/article/news...

Spanberger’s rebuttal and dominance of Woman’s Olympic feats—Jennifer Rubin nails it…worth an end-to-end read substack.com/@jenrubincon...

I have entirely deleted my X/Twitter account today. A sense of relief has ensued.

He’s too busy making podcasts about 2020 to talk about his supposed job today.

You can't buy a rotisserie chicken for humans with SNAP $, but you can buy rotisserie chicken-flavored cat and dog toothpaste (last line) with Arizona ESA $.

I discussed new Arizona ESA data with Arizona 12 News’ Craig Harris. 20% of transactions deemed unallowable. Imagine letting public schools spend taxpayer dollars with this little oversight or auditing. We wouldn’t. Release the data, and let the public see what it’s funding.

Not a well thought out ad to learn from an "educational program" for scientists to learn how to buy/use their instruments

Bring it

amazing that Tensions can deploy tear gas and abduct 5 year olds. the new york times is undefeated.

If I could ask everyone outside Minnesota to read one thing to understand what's going on there (on ICE's side, not the community response), my current pick would be this public Facebook post by @erinmayequade.bsky.social, a state legislator in Apple Valley, an outer-ring suburb of Minneapolis

shel silverstein was a prophet

More news (not good) from NIH The renewal request from National Institute of Neurological Diseases and Stroke Director Walter Koroshetz has been denied. I guess the NIH_leadership™ needed another position to fill with their time-tested recruitment process.

Dr @lucygossage.bsky.social was the first keynote at our 2025 Retreat. Oncologist, professional Ironman champion, and founder of 5K Your Way, Dr Gossage also did her PhD at @cruk-ci.bsky.social. Recalling this time, she said "completing a PhD and training for an Ironman are remarkably similar!"

Words of wisdom from a trusted Nobel Laureate…most of science is troubleshooting failure. Perhaps this is true of the rest of our lives as well, where success overcoming internal and external challenges, while keeping a positive spirit = contentment.

Known for decades as the Big Three of Groundbreaking Research - and now first in line for federal grants

This is heartbreaking 💔 to read. Thank you 🙏 for sharing this with us. I want to apologize to you on behalf of real Americans. It’s a painful reminder that we must keep resisting these harmful policies so we don’t lose more people like @wwenneuro.bsky.social, whom we spent over a decade training.

A thought article written by a thoughtful human, touching on the essential nature of human language. “Why Even Basic A.I. Use Is So Bad for Students” www.nytimes.com/2025/10/29/o...

I can’t wait for the day we get to call him Mayor Mamdani.

The authors suggest this may have allowed “speech-relevant neurons to accommodate elevated levels of FOXP2 without toxicity associated with protein aggregation”. This reminded me of the discussion of Parvalbumin in this paper on vocal learning by @erichjarvis.bsky.social

ICYMI: “And now, a response from the leader of the frog resistance...” 🐸 🎵 #Colbert

Congratulations to Princeton's Tom Muir, one of the most creative and thoughtful scientists I know, for being awarded the BMS Enzyme Chemistry & Chemical Biology Award chemistry.princeton.edu/news/tom-mui...

An entirely unnecessary fold. Adding “this celebration is open to everyone” - as we have done for all affinity events and celebrations at Princeton - makes these events legal.

Thanks for posting a path to directly "chat" with Jay Bhattacharya-encouraging everyone to submit comments/questions! Here is mine: "A Physician's credo is to do no harm. Either step up and be a Physician, stop ripping apart the efforts of so many to do good, or look in the mirror and step down."

Went for a walk to Central Park, New York and ran into a massive protest. Decided to join and document. Thousands of marchers were protesting everything the Trump administration and his supporters represent, walking around Trump Tower and then onto the park. I post the messages that resonated most.

Massive protest in New York against the current administration.

Shout out to @asiepel.bsky.social and his team for their extremely thoughtful collaboration, helping us solidify findings of human-specific NOVA1 variants-RNA regulation's contribution to the origin and contribution to human vocalization -- either I missed your original handle or welcome to Bluesky!

Thank you Mai You also shone with your insightful work & beautiful presentation 😊 Nice to be able to some of my Social sensibility @ an #RNA symposium! The PG version of my socks underscore my deep belief that Hate will Lose (& heartfelt thanks to @jenjennings.bsky.social for the Social Socks)!

Attending a March for mRNA wasn’t on my lifetime bingo card, but at this point… it feels like it needs to happen. @darnelr.bsky.social @adarnell.bsky.social

Can't help but be proud of the outspoken wisdom and bravery of the amazing Nobel Laureate @ardemp.bskyverified.social ... a role model for scientists everywhere www.cnn.com/2025/04/09/h...

Orange muppet shouting out for inseparability of science and truth

A study from Richard Lifton and @yale.edu colleagues in @pnas.org finds that a mix of inherited and de novo mutations in 60 genes contribute to 10% of congenital heart disease cases. Many of the same mutations also contribute to neurodevelopmental disorders.

Scrubbing #mRNA from grant proposals is a five-alarm fire. Thanks to pioneers including @drewweissmanlab.bsky.social & Kariko, millions of lives have already been saved. Silencing mRNA research now would be a catastrophic step backward. @erictopol.bsky.social @carlbergstrom.com @carlzimmer.com

My husband studies mRNA, so it’s time for a rebrand: Republican Nucleic Acid. It's going to be tremendous. Just incredible, believe me. Everybody's talking about it. The best nucleic acid, maybe ever.

From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA

It just gets too painful sometimes… Trump Administration Ends Tracking of Kidnapped Ukrainian Children in Russia www.nytimes.com/2025/03/18/u...