The peer-reviewed version: www.science.org/doi/10.1126/...

🧵 New preprint led by @bingbrunton.bsky.social, @elliottabe.bsky.social, @lawrencehu.bsky.social We gave a worm brain control of a fly body and it walked What did we learn? Nothing, other than deep reinforcement learning is effective We call it the digital sphinx www.biorxiv.org/content/10.6...

The conference is quickly filling up! Don't wait to sign up. We also received some funding and can offer fellowships to graduate students and postdocs. Won't cover the whole cost but will certainly make it much easier!

🧠⏰our latest paper is out now: how each neuron ages differently allowed us to define in silico screens for new therapeutic molecules that could prevent neurodegeneration @cecad.bsky.social @unicologne.bsky.social @uniklinikkoeln.bsky.social @meyerdh.bsky.social www.nature.com/articles/s43...

🔬 Discover the latest advances from Labex IBEID We have released a new white paper highlighting recent scientific and technological advances from the partners. ➡️ Key results ➡️ Latest innovations ➡️ Future challenges for Emerging Infectious Diseases research www.labexibeid.fr/en/ibeid-whi...

Not all bacteria are beneficial in every context. We found that enriching Drosophila with a commensal bacterium reduces tolerance to viral infection. The effect was virus-specific and occurred without changes in viral load, immune gene expression or intestinal damage. rdcu.be/eZ4Sd

We just uploaded our most recent paper to @biorxivpreprint.bsky.social and submitted the manuscript for publication. We are really excited with this collaboration between our lab (ColladoLab) @cimususc.bsky.social and the lab of @hanli-pasteur.bsky.social @pasteur.fr

Kicking off 2026 the best way we know how: together! 🥐👑 Our annual Galette des Rois brought the team together, and Mori Yoshida claimed the crown for the 4th year running! 🎉 But the real treasure? These moments that unite us before another year of discovery. Here's to an incredible 2026! 🔬✨

If you want to help, you can share our story, check out our work at viralemergence.org, and - if you're the one in a million person who can save our project - reach out. (At this point, my job is to fundraise for the amazing scientists I work with, so they can focus on doing some actual science! 🦠)

Now published as version of record at @elife.bsky.social ! Layers of Immunity: Deconstructing the Drosophila effector response. The tools are now deposited in the VDRC (link ⬇️) elifesciences.org/articles/107... shop.vbc.ac.at/vdrc_store/d... #Drosophila #IDsky #SymbioSky #Infection #Immunology

All hail Caenorhabditis elegans, one of the most researched organisms on Earth. Collaborative data sharing in the nematode research community led to four Nobel Prize-winning discoveries about human development and disease. In PNAS: https://ow.ly/uNqU50Xyj4e

Version 2 is out! More comprehensive text plus new tissue- and pathway-specific analysis revealing how different viruses trigger systemic aging through diverse mechanisms. www.biorxiv.org/content/10.1...

In flies and worms, more pathogenic viruses caused greater aging acceleration, and the effect lingered even after clearance, new study reveals. #Aging #Infection #MicroSky #Virology 📖 shorturl.at/OeYVp ✍️ @rubengonzalez.bsky.social @castellosanjuan.bsky.social @salehlabparis.bsky.social @pasteur.fr

Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on. (Please repost to reach a broad audience.)

IT'S HAPPENING! 💥 I'm psyched to launch the collaboration between @qedscience.bsky.social & @openrxiv.bsky.social @biorxivpreprint.bsky.social! Preprint + q.e.d = your science is out there, and anyone can appreciate it. Let's care about making discoveries, and not on “getting published” (1/3) 👇

🧬 Thrilled to share our latest paper in @natmicrobiol.nature.com 📄 A collaboration to give the Flaviviridae (home to Zika, Dengue & HCV) a much-needed taxonomic re-think. Our at-scale AI structure prediction gave a complementary perspective on viral evolution. www.nature.com/articles/s41...

Apart from the AI junk part… the notion that one should not offer a potential mechanistic explanation for an observation, without first spending years & (unavailable) $$ trying to test possibilities before sharing the observation with others (who may be better equipped to investigate the mechanism)…

🪰 folks! I spoke to the Transmitter about FlyBase. As noted at flybase.org, bridge $ ran out and many staff were laid off. Good news is stopgap contributions will keep core FlyBase operations active. But community support remains essential. Please donate @FlyBase and share! 1/2 tinyurl.com/FlyBase

Last chance to download my book for free! It's still available until tomorrow.

What makes PhD students happy? Good supervision www.nature.com/articles/d41...

Science is so much fun!

I'm so excited to share this with all of you! This is the very first paper where I am the first author 🥹 Let me share some insights about our work 👇🧵(1/5): How do persistent viral infections impact the host? What happens when a fly becomes persistently infected by a virus?

Microbiome composition modulates the lethal outcome of Drosophila A virus infection https://www.biorxiv.org/content/10.1101/2025.10.16.682821v1

🦖 Something HUGE just hatched. Plasmidsaurus now offers RNA sequencing for gene expression analysis: • As fast as 3 day turnaround • $50/sample for academia, $80 for industry • Up to ~10M unique transcript 3’ end reads per sample • Interactive results Explore Plasmidsaurus RNA-Seq today.

1/3 What happens when a fly gets persistently infected by a virus? In our latest work, we established persistent infections to examine their impact on this model organism. By tracking four natural, persistent RNA viruses...

Dear JEDIs, as we are self-organizing using the #EDRC as a nucleator we decided it is time for a JEDI database to boost our network! If you identify as a JEDI, please contact us here or send a mail to [email protected] to be added to our database. #Drosophila @fly-eds.bsky.social

Cheaper defense first, costly one later. This makes sense. journals.plos.org/plosbiology/...

Virology lost one of his monuments, David Baltimore. To learn more about him and his contributions, I recommend (re)-listening to this great TWIV episode : www.microbe.tv/twiv/twiv-10...

if you have your team and grants, not forget to support @flybase.bsky.social www.philanthropy.cam.ac.uk/give-to-camb... meanwhile, we need to think longterm and protect this data, dl it, share it portal.datarescueproject.org/datasets/fly...

The 2025-26 Eco-Evo job list is out. Good luck to those applying! docs.google.com/spreadsheets...

This week, the capital of Evolution is Barcelona! Over 1900 evolutionary biologists are gathering for the biennial meeting of the European Society for Evolutionary Biology, coorganised with its Spanish sister #ESEB2025. Over 540 of us are on Bluesky! You can use these starter packs to connect: 1/n

Forecasting the effects of #epidemics is complicated by a population’s pathogen exposure history. @pfvale.bsky.social @chadisaadroy.bsky.social & Mike Boots argue for the use of experimental #DiseaseEcology to better understand the consequences of variations in #infection history 🧪 plos.io/4mdDVvW

We've tried to gather and unite the streptophyte algae community all around the world to join forces and develop tools and methods for these critters. Learn more about it on @currentbiology.bsky.social! With @jandevries.bsky.social, @dolfweijers.bsky.social, and (many) others! tinyurl.com/29n4zwen

The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field? That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience A 🧵 1/n

Anyone pushing forward a « microbiome and beyond » WS proposal, that would be an awesome topic… 😉

Thrilled to receive @anrs-mie.bsky.social grant with @lambrechtslab.bsky.social & @retrogenomics.bsky.social! Making mosquitoes intolerant to arboviruses. Thanks @pasteur.fr, @inserm.fr & @cnrs.fr for support. Exciting times for #ARBORETRO project! Stay tunned.

Hi #Drosophila folk: I'm advertising a 2-year #Postdoc, funded by a BBSRC grant on the genetic and immune determinants and evolutionary constraints underlying extreme pathogen transmission phenotypes. Deadline 29 April, details in the link below, or feel free to email: www.jobs.ac.uk/job/DMQ231/p...

Amazing new tools for studying fly immunity!! Fantastic work

It's finally out!!!! Our review on long-reads transcriptomics was published in @natrevgenet.bsky.social!! You can have a look at the paper here rdcu.be/efugl! We hope you like it 😀

A friend sends me that picture and I'm very happy of my 14 years fighting to get this model accepted within the ageing research community. A serendipitous discovery I made that really changes everything !

A new way to conduct GWAS meta-analysis? Preprint shows Genomic Network Analysis can be used to identify conditionally independent associations between traits, controlling for shared genetic signals. Also enables multi-level biological analysis within the framework to probe underlying aetiology🧬🖥️

Scientists in China developed SCLIMS, a tool that links metabolism to oxidative stress at the single-cell level. They found that metabolic differences predict cell fate under stress and that key metabolites can extend lifespan in C. elegans. www.nature.com/articles/s41...

To all the newskies, welcome! #HiSciSky As #firstgen PI at BCM in Houston, my lab studies how the #microbiome alters host physiology using genetics & genomics in #Celegans. Our lens is #BasicResearch, but aim to promote human health on earth and beyond. 🧪🖥️🧬 #AcademicSky #MicroSky 1/3

European Drosophila Board election call for nominations. Join the EDB to represent and support Drosophila research in Europe! Five representatives will be elected for different regions. Check our election page for details: europeandrosophilasociety.org/european-dro... #Drosophila, #EDRC2025

Please consider nominating deserving colleagues (including yourselves) who would be excellent candidates for five open positions on the Council, including Nominations for President-elect, Secretary, Treasurer, and 2 Councilors. Please share widely! @official-smbe.bsky.social

Genome sequencing & single-cell transcriptomics continue to produce findings that challenge the idea that #cancer is purely a genetic disease. This Essay delves into #omics data that questions the somatic mutation theory & presents alternative theories based on GRNs & tissue fields.🧪 plos.io/3DRtAEW

Thrilled to share 'BuzzWatch', my post-doc work with Felix Hol and @lambrechtslab.bsky.social ➡️Filming mosquitoes in a cage with a €15 camera but for 700h(1month) revealed fascinating insights into their behavior⌛🦟🎥⏳ preprint🔍 doi.org/10.1101/2025... DIY guide 🛠️ theomaire.github.io/buzzwatch 🧵⬇️

1/ Transposable elements are often called "jumping genes" because they mobilize within genomes. 🧬 But did you know they can also jump 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 cells? 🤯 Our new study reveals how retrotransposons invade the germline directly from somatic cells. www.biorxiv.org/content/10.1... A short thread 🧵👇

I am happy to announce with @hanli-pasteur.bsky.social that we'll organise a summer school titled "Senescence from Cell Cultures to Humans through Model Organisms" in Paris, Fr on June 23-24, 2025 Aimed at 2nd and 3rd year PhD student + postdocs Submit your provisional project tinyurl.com/2uhfzxbp

Hello everyone on Bluesky! 🧪 We are EMBO, the organization of more than 2,100 leading researchers that promotes excellence in #lifesciences in Europe and beyond. Read more: www.embo.org/about-embo/m...