Pedro Vale
@pfvale.bsky.social
📤 2255
📥 1248
📝 159
Ecology & Evolution of Infection Dynamics lab, Edinburgh, UK
https://pedrovale.bio.ed.ac.uk/
pinned post!
This piece on infection history as a driver of individual heterogeneity in infection outcomes was fun to think about and to write with
@chadisaadroy.bsky.social
and Mike Boots. Also suggest that systems like
#Drosophila
can offer useful tools to tackle the epidemiological consequences.
add a skeleton here at some point
about 2 months ago
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*Congratulations* to former Darwin Trust-funded PhD student Arun Prakash for being awarded the Alfred Russel Wallace award from
@royentsoc.bsky.social
for his PhD on
#immune
regulation of disease
#tolerance
and immune
#priming
in
#Drosophila
!
@edinburghbiology.bsky.social
@uoe-eid.bsky.social
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Former PhD student wins the Alfred Wallace Award for significant contribution to the science of entomology | Edinburgh Infectious Diseases | Edinburgh Infectious Diseases
September 2025: Dr Arun Prakash, a Darwin Trust PhD student, has been retrospectively awarded the prestigious award from the Royal Entomological Society for his 2021 thesis ''Immune Regulation Of Dise...
https://edinburgh-infectious-diseases.ed.ac.uk/former-phd-student-wins-the-alfred-wallace-award-for-contribution-to-entomology
18 days ago
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reposted by
Pedro Vale
PLOS Biology
about 2 months ago
Forecasting the effects of
#epidemics
is complicated by a population’s pathogen exposure history.
@pfvale.bsky.social
@chadisaadroy.bsky.social
& Mike Boots argue for the use of experimental
#DiseaseEcology
to better understand the consequences of variations in
#infection
history 🧪
plos.io/4mdDVvW
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The ghost of infections past: Accounting for heterogeneity in individual infection history improves accuracy in epidemic forecasting
Variable pathogen exposure history contributes to individual immune differences, complicating epidemic forecasting. This Essay argues that experimental disease ecology can offer powerful tools and app...
https://plos.io/4mdDVvW
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This piece on infection history as a driver of individual heterogeneity in infection outcomes was fun to think about and to write with
@chadisaadroy.bsky.social
and Mike Boots. Also suggest that systems like
#Drosophila
can offer useful tools to tackle the epidemiological consequences.
add a skeleton here at some point
about 2 months ago
1
17
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"The myth of meritocracy in science collapses under the financial sacrifices expected at every career stage. From unpaid internships and self-funded conferences to underpaid positions, these hidden costs disproportionately exclude those without generational wealth, compounded by race and gender."
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Too poor to science: How wealth determines who succeeds in STEM
From student to researcher, a career in science can come with a high price tag. This Perspective explores how persistent financial barriers limit who can succeed in science, revealing how wealth shape...
https://dx.plos.org/10.1371/journal.pbio.3003243
3 months ago
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reposted by
Pedro Vale
Trends in Microbiology
4 months ago
Providencia rettgeri
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Providencia rettgeri
Providencia rettgeri is a rod-shaped, urease-producing, Gram-negative bacterium. It is motile, owing to the presence of flagella, which aid in its movement and colonisation of a wide range of environments. It is prevalent in hospitals and other healthcare settings, particularly on medical equipment, and therefore plays an increasingly important role in nosocomial infections. P. rettgeri produces mannose-resistant Proteus-like (MR/P) fimbriae, which allow adhesion to uroepithelial mucosal cells and to exfoliated urinary cells, contributing to its role in urinary-tract infections.
http://dlvr.it/TKnby4
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reposted by
Pedro Vale
Caroline Amoroso
4 months ago
Hope this primer proves helpful to anybody interested in infection avoidance. It was certainly a pleasure to write with
@akgibson.bsky.social
and
@pfvale.bsky.social
l!
add a skeleton here at some point
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This primer on infection avoidance was incredibly fun to write with
@cr-amo.bsky.social
and Mandy Gibson. We cover its taxonomic breadth, mechanisms and evolution, and its importance across fields as diverse as public health, conservation, and agriculture. 🧪
www.cell.com/current-biol...
#SymbioSky
4 months ago
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Providencia rettgeri is a commonly employed
#Drosophila
pathogen. It also has an extensive AMR profile causing opportunistic infections in hospital settings. I recently realised I know less about it than I should, so here is my homework.
www.sciencedirect.com/science/arti...
#Microsky
#MEvosky
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Providencia rettgeri
https://www.sciencedirect.com/science/article/pii/S0966842X25001386
4 months ago
2
6
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hollyyfc.github.io/lme4u/
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Interpretation and Diagnostics for lme4 Hierarchical Models
Interpret and diagnose linear mixed-effects models fitted with lme4. Provides tools for summarizing model output, visualizing assumptions checks, and performing hypothesis tests.
https://hollyyfc.github.io/lme4u/
5 months ago
0
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A new preprint from the lab, where we apply complex systems and machine learning approaches to identify transitions between life and infection-induced death in
#Drosophila
.
www.biorxiv.org/content/10.1...
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Detecting infection-related mortality using dynamical statistical indicators of high-resolution activity time series
Predicting transitions between health, disease, and death across biological systems remains an important challenge with significant implications for both ecological management and medical intervention...
https://www.biorxiv.org/content/10.1101/2025.04.21.649753v1
5 months ago
0
5
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Really excited to finally start this project with
@andreadwilson.bsky.social
, using
#Drosophila
as a model for experimental epidemiology and evolution to explore the genetic determinants and evolutionary constraints on extreme pathogen transmission phenotypes.
add a skeleton here at some point
5 months ago
0
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Hi
#Drosophila
folk: I'm advertising a 2-year
#Postdoc
, funded by a BBSRC grant on the genetic and immune determinants and evolutionary constraints underlying extreme pathogen transmission phenotypes. Deadline 29 April, details in the link below, or feel free to email:
www.jobs.ac.uk/job/DMQ231/p...
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Postdoctoral Research Associate at The University of Edinburgh
Apply now for the Postdoctoral Research Associate role on jobs.ac.uk - the leading job board for higher education jobs. View details.
https://www.jobs.ac.uk/job/DMQ231/postdoctoral-research-associate
6 months ago
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An interesting, tenured, Principal Researcher position at CIBIO in Northern Portugal, focused on the study of virus-host
#co-evolution
, with emphasis on the
#evolution
of
#immune
system genes and the impact of emerging diseases on wildlife.
www.cibio.up.pt/en/jobs/tenu...
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TENURE, 1st Edition: 2 positions- BIOPOLIS2025-15 - Job Opportunities - Cibio
The mission of the Research Centre in Biodiversity and Genetic Resources is to develop world-class research in the areas of biodiversity and evolutionary bi
https://www.cibio.up.pt/en/jobs/tenure-1st-edition-2-positions-biopolis2025-15/
6 months ago
0
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reposted by
Pedro Vale
Tobias Engl
6 months ago
A long, long time ago, we started this review project during the first Coron lockdown, but if finally made it out into the world - Origin and function of beneficial bacterial symbioses in insects!
@naturerevmicro.bsky.social
add a skeleton here at some point
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reposted by
Pedro Vale
Katerina Guschanski
6 months ago
Dental calculus, the preserved oral microbiome, is an absolute treasure trove of information that can be interrogated across thousands of years. But how to make it work? In a new preprint,
@markella-morait.bsky.social
asks this questions using >30 mammalian species:
doi.org/10.1101/2025...
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reposted by
Pedro Vale
Priscilla Akyaw
7 months ago
Time to give an update on the fantastic work by
@taniafpaulo.bsky.social
during her PhD, now published in
@royalsocietypublishing.org
on the evolution of resistance and disease tolerance mechanisms to oral infection in
#Drosophila
royalsocietypublishing.org/doi/10.1098/...
#infection
#immunity
🤓🎊
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Evolution of resistance and disease tolerance mechanisms to oral bacterial infection in Drosophila melanogaster | Open Biology
Pathogens exert strong selection on hosts that evolve and deploy different defensive strategies, namely minimizing pathogen exposure (avoidance), directly promoting pathogen elimination (resistance) a...
https://royalsocietypublishing.org/doi/10.1098/rsob.240265
1
12
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reposted by
Pedro Vale
SalehLab
7 months ago
Here we go again!!! Thanks to
@rubengonzalez.bsky.social
a brilliant postdoc in the lab, I made my first baby steps into the aging field... Be kind and supportive 😀 I find the results totally exciting! and so much to do now!
#ProudPI
#LoveVirology
add a skeleton here at some point
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reposted by
Pedro Vale
RuthLeyMicro
7 months ago
So excited to share this latest work by
@kelseyhuus.bsky.social
!!! She shows that flagellin in the human gut affects whether or not people develop fever in response to vaccine, and the amount of flagellin reflects diet
add a skeleton here at some point
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reposted by
Pedro Vale
The Interactive Fly
7 months ago
Prakash, A., Fenner, F., Shit, B., Salminen, T. S., Monteith, K. M., Khan, I., Vale, P. F. (2024). IMD-mediated innate immune priming increases
#Drosophila
survival and reduces pathogen transmission. PLoS pathogens, 20(6):e1012308
journals.plos.org/plospathogen...
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IMD-mediated innate immune priming increases Drosophila survival and reduces pathogen transmission
Author summary When we are vaccinated, our immune response is able to respond quickly if we are ever exposed to the same pathogen in the future. Unlike humans, the immune systems of invertebrates, suc...
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1012308
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What is a model organism?
asm.org/Articles/202...
#MicroSky
#MEvoSky
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What is a Model Organism? Moving Beyond E. coli | ASM.org
For all its prominence in research, E. coli does not reflect Earth’s rich microbial diversity. Scientists are rethinking what can—and should—constitute a model organism moving forward.
https://asm.org/Articles/2025/February/What-is-a-Model-Organism-Moving-Beyond-E-coli
7 months ago
1
25
5
"Here, we track the development of balancing selection theory over the last century and provide an accessible review of this rich collection of models."
#evobio
add a skeleton here at some point
7 months ago
0
7
4
reposted by
Pedro Vale
Carl T. Bergstrom
7 months ago
This excellent interactive tutorial on misleading data visualizations explores the idea of a "counter chart" — the graph you draw in response to refute a misleading claims
flowingdata.com/projects/dis...
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Defense Against Dishonest Charts
This is a guide to protect ourselves and to preserve what is good about turning data into visual things.
https://flowingdata.com/projects/dishonest-charts/
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Live imaging of individual symbiotic bacterial cells colonizing the gut of living Drosophila melanogaster show that Lactiplantibacillus plantarum specifically recognizes the fruit fly foregut as a distinct physical niche.
www.science.org/doi/full/10....
#Symbiosky
#Drosophila
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https://www.science.org/doi/full/10.1126/science.adp7748#tab-citations
7 months ago
0
3
2
reposted by
Pedro Vale
bioRxiv Evolutionary Biology
7 months ago
A century of theories of balancing selection
https://www.biorxiv.org/content/10.1101/2025.02.12.637871v1
0
11
5
reposted by
Pedro Vale
RES Publications
8 months ago
The new March issue of
#RESPhysEnt
, Vol. 50 Issue 1, opens with an editorial: Key questions for future research in Physiological Entomology 👀doi/10.1111/phen.12481 If you’d like to submit an article on any of these key research areas, get in touch!
@wybouw.bsky.social
@tbuescher.bsky.social
1
8
5
reposted by
Pedro Vale
Ally Phillimore
8 months ago
Fieldwork opportunity: We're looking to hire a field assistant for the
www.phenoweb.org
project starting 1 April. Please repost.
#phenology
#fieldwork
#birdringing
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reposted by
Pedro Vale
Ben Longdon
8 months ago
V neat: "A naturally occurring mitochondrial genome variant confers broad protection from infection in Drosophila" from Tiina Salminen, Laura Vesala
@pfvale.bsky.social
et al
journals.plos.org/plosgenetics...
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A naturally occurring mitochondrial genome variant confers broad protection from infection in Drosophila
Author summary The strength of immune response and the disease symptoms vary among individuals even when exposed to the same pathogen. Much of this variation is due to the genes directly involved in a...
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011476
0
8
4
reposted by
Pedro Vale
Edinburgh Infectious Diseases
8 months ago
Really interesting day discussing impacts of climate change on vector borne diseases workshop today. Lots of great science and discussion about exciting projects to take forwards.
@keithrmatthews.bsky.social
#reecelab
@roslininstitute.bsky.social
@amypedersen.bsky.social
0
7
3
reposted by
Pedro Vale
Darren Obbard
8 months ago
From
@blongdon.bsky.social
et al!
doi.org/10.1093/evle...
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Positive correlations in susceptibility to a diverse panel of viruses across Drosophilidae host species
Abstract. Our ability to predict the emergence of novel viruses relies on there being generalizable patterns in the susceptibilities of hosts to novel infe
https://doi.org/10.1093/evlett/qraf002
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An important study showing that prolonged exposure to higher temperatures makes
#Aedes
albopictus more tolerant of
#viral
infection - with important implications for vector-borne diseases in a warming world.
#symbiosky
#evovir
@uoe-eid.bsky.social
add a skeleton here at some point
8 months ago
0
8
3
reposted by
Pedro Vale
Priscilla Akyaw
8 months ago
I am very happy to see this first part of my PhD work go online now! 💃🏾 We explored alternative strategies to elicit
#diseasetolerance
in
#Drosophila
melanogaster in response to oral
#infection
with a natural bacterial
#pathogen
,
#Pseudomonas
entomophila. (Thread)
add a skeleton here at some point
1
3
1
reposted by
Pedro Vale
Michael Brockhurst
8 months ago
🚨 Job alert 🚨 — are you interested in understanding how mobile genetic elements and defence systems shape bacterial genome evolution? 🧬 🧪 🧫 🦠 2x 5-year research positions available in experimental evolution
@mermanchester.bsky.social
Join us!
#microsky
www.jobs.manchester.ac.uk/Job/JobDetai...
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Research Associate in Experimental Evolution:Manchester
https://www.jobs.manchester.ac.uk/Job/JobDetail?JobId=31500
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PhD Summer School on Host-Microbe Symbioses. Awesome topic. Unbeatable location.
#symbiosky
#microsky
#evobio
gimm.idloom.events/phd-summer-s...
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PhD Summer School on Host-Microbe Symbioses 2025
PhD Summer School on Host-Microbe Symbioses Gulbenkian Institute for Molecular Medicine (GIMM) & Católica Biomedical Research Centre (CBR) July 06 -19, 202...
https://gimm.idloom.events/phd-summer-school-2025/
8 months ago
1
20
17
This looks like an outstanding meeting, likely of interest to
#Drosophila
and
#EvolSky
🧪communities.
add a skeleton here at some point
8 months ago
0
4
1
reposted by
Pedro Vale
Edinburgh Infectious Diseases
8 months ago
⭐ NEW PUBLICATION ⭐ A naturally occurring mitochondrial genome variant confers broad protection from infection in Drosophila
@pfvale.bsky.social
Read more ➡️
https://buff.ly/3EcXnYt
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Support a fantastic society journal by submitting your insect physiology work to
@royentsoc.bsky.social
PHEN. In the upcoming January volume, we discuss some of the key questions for future research in physiological
#entomology
.
#symbiosky
🐜🐝🦋🦟🧪
resjournals.onlinelibrary.wiley.com/share/YJQDXW...
8 months ago
2
15
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reposted by
Pedro Vale
Edinburgh Infectious Diseases
8 months ago
💭Check our brand new Research Focus - featuring publications from across the Edinburgh Infectious Diseases network!
@pfvale.bsky.social
@richardsloanlab.bsky.social
@dbogaert.bsky.social
@fionagreco.bsky.social
Full article here ➡️
edinburgh-infectious-diseases.ed.ac.uk/news-and-eve...
0
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reposted by
Pedro Vale
Royal Entomological Society
8 months ago
RES has joined Bluesky! We are excited to share fascinating science, news, events & more. To start, we’re featuring the
#LargeBlueButterfly
🦋 Our
#Conservation
Science team recently published ground-breaking findings on the dispersal rates of this
#EndangeredSpecies
🔽
https://buff.ly/3Wz5QLU
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Looks like a tremendous amount of work from Rodrigo Cogni's group, and a very useful quantitative review of the negative effects of viral infection across insect taxa.
#symbiosky
#virosky
#InsectEcol
#infection
#evolsky
add a skeleton here at some point
8 months ago
1
6
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reposted by
Pedro Vale
Sam Brown
8 months ago
Hello world! I'm starting out on bluesky with a job posting - we're looking for lab research tech who shares our love of bugs. More info here
brownlab.biology.gatech.edu/opportunities/
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Opportunities
https://brownlab.biology.gatech.edu/opportunities/
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reposted by
Pedro Vale
Jayna Raghwani
9 months ago
Please share widely! We are recruiting a 3-year postdoc at the RVC to develop new methodology to infer epidemic dynamics from wild animal viromes sampled across changeable environments. Further details:
jobs.rvc.ac.uk/vacancy.aspx...
Feel free to reach out with any questions. Deadline Feb 9th
0
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reposted by
Pedro Vale
René Ketting
9 months ago
www.academics.com/jobs/univers...
Please help us find a new colleague at Mainz University. Thanks!
#evolbiol
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University Professor of Life History Evolution W3 - Johannes Gutenberg-Universität Mainz
Johannes Gutenberg-Universität Mainz looks for University Professor of Life History Evolution W3 in Mainz - apply now!
https://www.academics.com/jobs/university-professor-of-life-history-evolution-w3-johannes-gutenberg-universitaet-mainz-mainz-1094130
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Absolutely astounding. Experimental horizontal transfer of
#phage
derived genes to
#Drosophila
confers innate immunity to
#parasitoids
.
#symbiosky
#microsky🧪
add a skeleton here at some point
9 months ago
1
52
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reposted by
Pedro Vale
Elli Leadbeater
10 months ago
PhD position available! Are you interested in how natural selection shapes the evolution of animal memory? Be part of our experimental evolution plans at UCL
@ucl-pnl.bsky.social
@treesdla.bsky.social
, co-supervised by Flo Camus
@fcamus.bsky.social
.
www.trees-dla.ac.uk/projects/evo...
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Evolutionary ecology of animal memory | UCL Trees
This project seeks to explore how memory evolves in response to the ecological tasks that animals face in their natural environment. Associative memory exists in some form in almost all animal species...
https://www.trees-dla.ac.uk/projects/evolutionary-ecology-animal-memory
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reposted by
Pedro Vale
Dutchscientist (the real one)
9 months ago
jobs.surrey.ac.uk/Vacancy.aspx...
At the University of Surrey, we are looking for a new colleague. Join us as Lecturer/Senior Lecturer in Immunity and Infection Biology at the School of Veterinary Medicine. Do get in touch for any queries or forward to your networks 🙂
#MicroSky
#IDSky
#MicrobiomeSky
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Job Vacancy at the University of Surrey: Lecturer/Senior Lecturer in Immunity and Infection Biology
The University of Surrey is an international University with a world class teaching and research profile that is innovative, forward thinking and achieving notable results. Our research seeks to addre...
https://jobs.surrey.ac.uk/Vacancy.aspx?ref=060124
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reposted by
Pedro Vale
Animal Ecology Uppsala
10 months ago
📣 We are recruiting! Please spread the word! We look to hire an associate professor in animal ecology, specializing in evolutionary ecology. Apply by Feb 7 2025. Come join us in Uppsala, Sweden! Application page and contact info 🔗👇
#ecology
#evolution
#job
www.uu.se/en/about-uu/...
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Associate Professor in Animal Ecology with specialization in Evolutionary Ecology - Uppsala University
Associate Professor in Animal Ecology with specialization in Evolutionary Ecology , Department of Ecology and Genetics, Uppsala University
https://www.uu.se/en/about-uu/join-us/jobs-and-vacancies/job-details?query=771392
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"We describe a
#mtDNA
variant that confers protection against variety of pathogens in
#Drosophila
. This protection was at least partially caused by enhanced cell-mediated innate
#immunity
, including higher numbers of immune cells prior to and during infection."
journals.plos.org/plosgenetics...
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A naturally occurring mitochondrial genome variant confers broad protection from infection in Drosophila
Author summary The strength of immune response and the disease symptoms vary among individuals even when exposed to the same pathogen. Much of this variation is due to the genes directly involved in a...
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011476
10 months ago
2
38
19
"What makes a super-spreader? Unravelling the genetics of host infectiousness" Funded
#PhD
position in my lab exploring the drivers of host heterogeneity in pathogen transmission. Get in touch if interested. Deadline 17 Jan 2025.
#HostPathogen
#DiseaseEcology
www.findaphd.com/phds/project...
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EastBio: What makes a super-spreader? Unravelling the genetics of host infectiousness. at University of Edinburgh on FindAPhD.com
PhD Project - EastBio: What makes a super-spreader? Unravelling the genetics of host infectiousness. at University of Edinburgh, listed on FindAPhD.com
https://www.findaphd.com/phds/project/eastbio-what-makes-a-super-spreader-unravelling-the-genetics-of-host-infectiousness/?p179625
10 months ago
0
20
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reposted by
Pedro Vale
Journal of Evolutionary Biology
10 months ago
Opportunity! We are looking for new editors - application deadline is Monday 20th January. Positions available: Associate Editors Handling Editor Commissioning Editor Details here:
jevbio.net/call-for-edi...
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