🩺🦠How well do #OPAT antimicrobials really hit PK-PD targets? Our UK prospective study shows good attainment across agents, while demonstrating the feasibility of #TDM to support #precisiondosing in outpatient infection care doi.org/10.1093/jac/... @tmrawson.bsky.social @mgilchrist123.bsky.social

80 years after the Nobel Prize for penicillin, antimicrobial resistance is one of societies toughest challenges. GSK, the Fleming Initiative, and the @ineosoxford.bsky.social hosted leaders at the Royal Society of Medicine to advance the global response.

Now published! www.nature.com/articles/s41... Very nice collaboration with Hoogenboom ( @ucl.ac.uk ) and Bonev ( @uniofnottingham.bsky.social ) labs.

Incredible week with @camo-net.bsky.social UK and India! Diving into all things AMR surveillance, data systems and stewardship strageties! Grateful to our hosts at Amrita for having us! 🇬🇧🇮🇳 #globalhealth #AMR

Interesting paper Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China 'A. baumannii is evolving from a low-virulence, multidrug-resistant pathogen to a more virulent one' www.nature.com/articles/s41...

And this is what microbiologists do for #Easter. #AgarArt #ScienceIsFun 🦠🧫🔬👨🏻‍🎨🎨🖌️🐣🐇🥚

Discovery of a new class of natural antibiotics with a new mode of action to address antimicrobial resistance, a major unmet need @mcmasteruniversity.bsky.social @nature.com www.nature.com/articles/s41...

One week left to apply for this BBSRC funded PhD position in the Duncan lab, cosupervised by @thecopperdoctor.bsky.social and @ruamicro.bsky.social www.findaphd.com/phds/project...

Please RT. Post-doc opportunity alert! 💥 Come join our team (thelowlab.org) at Imperial, London, working on bacterial secretion systems. The position is funded by the Wellcome Trust. For more details and to apply please see www.imperial.ac.uk/jobs/search-...

I am delighted to update that our work presented at the ICID 2024 has been published today: Neonatal intensive care units as a driver and reservoir of invasive infections: an example of the emerging Staphylococcus capitis multidrug-resistant NRCS-A clone www.sciencedirect.com/science/arti...

New online! The role of bacterial metabolism in antimicrobial resistance

McMaster researchers developed the free ESKAPE Model, an AI tool for identifying new antibiotics against resistant pathogens, allowing researchers to screen up to 20,000 chemicals daily. How to access is not yet shared, but stay tuned 😊 brighterworld.mcmaster.ca/articles/esk...

BIGSdb v1.50.0 has been released, introducing support for registering fields from the output of third-party analysis tools and then using these in queries and analyses (image shows querying hicap results in H. influenzae database).

🆕Read my short perspective on @daganlab.bsky.social's intriguing @currentbiology.bsky.social paper that examined plasmid-mediated gene mobilisation by comparing plasmid cargoes with chromosomal sequences across almost 2000 isolates, now in Trends in Microbiology 💻💫🧬 #MicroSky

At ISID 2024 to present work with Nina Zhu & Tim Rawson on using AI to predict acute kidney injury from vancomycin & VPT therapy! Visit poster #1 at 12 PM today! @CAMO_Net1 @HPRUamr #AMR #AIinMedicine Also chat to me about Microbiology Society's Knocking out AMR project 😊

JOB CLAXON! I am recruiting a post-doctoral researcher on a BBSRC-funded project (36 months) on the genetics and functional genomics of vancomycin resistance in enterococci. Further details here: edzz.fa.em3.oraclecloud.com/hcmUI/Candid... Please DM or email me if you want to discuss this post.

Hot off the press - some light reading on Shigella sonnei! 🧪🧫🧬 With @ksbakes.bsky.social @yekwah.bsky.social @sydneylmiles.bsky.social @sergemostowylab.bsky.social @lshtmamrcentre.bsky.social and a bunch of others not yet on bluesky
rdcu.be/d1EAF

Incredible graphic - the myriad of ways that bacteria defend themselves against antibiotics. 14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell www.sciencedirect.com/science/arti...

HERE's our paper revealing phylogenomic variations in #Salmonella Agona that lead toward persistent infection dx.plos.org/10.1371/journal.ppat.1012679 Great job to our @Emmabeansworth.bsky.social, @gemma-langridge.bsky.social, @winnielee.bsky.social & UKHSA's Marie Chattaway & Amina Ismail Ahmed

Hello Blueskis. Here is a starter pack of General Microbiology. It's a small list currently. Please feel free to self-nominate and I will add you. go.bsky.app/QgSQHJ9

PhD studentship available. The project is VERY interdisciplinary, combing social science, biophysics and microbiology to understand inequalities of UTIs treatment and replicate them in vitro to help choose the correct antibiotic. Pls share, home students only #AMR #MicroSky tinyurl.com/45d8h54u

It's HERE! Our long awaited paper revealing phylogenomic variations in #Salmonella Agona that lead toward persistent infection in @PLOSPathogens https://t.co/iDY38oiVbJ Great job to our @EmmaBeansworth, @gemma_langridge,@Winni_l08 & @UKHSA's @MarieChattaway & Amina Ismail Ahmed

Research, prevention, awareness - Controlling Microbes to Fight Infections

It's HERE! Our long awaited paper revealing phylogenomic variations in #Salmonella Agona that lead to persistent infection in @PLOSPathogens dx.plos.org/10.1371/jour... Thanks Gemma Langridge, UKHSA's, Marie Chattaway & Amina Ismail Ahmed & Winnie Lee Now to the next 3 papers..

Your regular reminder about editorial standards at Frontiers.

🌍 World Antimicrobial Awareness Week! 🦠 Antimicrobial resistance is a threat to global health. Misuse of antibiotics fuels resistance and makes infections harder to treat. Be part of the solution: Follow medical advice and help spread awareness! #WAAW #AMR #GoBlue #OneHealth youtu.be/_Qy3aTKiVLE

It was great to catch up with one of our favorite customers @winnielee.bsky.social at #genomescienceUK in Bristol 🥰 #gsuk24 #MicrobialGenomics

Great talk on the genomic population of bloodstream Klebsiella spp. in Southwest UK Thanks for the shout out @winnielee.bsky.social 🥰 it's always fun to hear what happens to the data we send out 🥳 #gsuk24 #Genomescienceuk #AMR

#Postdoc alert! wanna come do some postdoc-ing with us in beatiful Tübingen!? #Evolution & #genomics enthusiasts, we want you! 💻🧬🔬 You don't need to love #Drosophila, but if you do, it is a plus :) pallareslab.org/we-are-hirin...

A little over a week left to apply for this PhD position in Glasgow. Come study how Staphylococcus aureus transitions from the nasal to bloodstream niche, and how the microbiome influences colonisation status

Still time to apply for this PhD. Deadline is January 31st. #microsky

1 week left to apply for these 4 year post-doc positions in my lab

En route to Glasgow! Who wants to join me? 🗓️ Reminder that the deadline for the PhD is January 31st. Details below. #microsky 🏴󠁧󠁢󠁳󠁣󠁴󠁿🧫

We are expanding our team again! If you are looking for a bioinformatics post please take a look 🤩

🚨JOBS🚨🦠🔬 Two 4 year post-docs available in my lab at Warwick. Looking for experts in super-resolution #microscopy, single molecule fluorescence, FRET or protein biochemistry. Visa+NHS fees covered. Salary~£40K. Two exciting team science projects with outstanding collaborators #microsky

🔔New preprint! In which we explore the ecological consequences of plasmid-bacterial compensatory evolution using models and experiments. With Rosanna Wright, Jamie Wood, Mike Bottery, @brockhurstlab.bsky.social and others 🧫💫🦠 www.biorxiv.org/content/10.1...

First official post on here! Viva done and dusted! Thanks Ed Feil and Alice Halliday for examining, as well as Darryl Hill for chairing! Interesting discussions and awesome experience! Matthew Avison looking very happy here 😊

3-year Junior Research Fellowship at Trinity College, Oxford in Biochemistry/Pathology/Biomedical Sciences, broadly defined. Synergy with current researchers at Trinity (incl. myself!) very much encouraged. trinity.ox.ac.uk/vacancies Ideally suited for somebody 1/2

New PhD position in the MRC Doctoral Training Programme for an Oct 2024 start with @milja001.bsky.social and myself as supervisors. The gut phageome as a driver for microbiome dynamics in critically ill patients Scroll down on more.bham.ac.uk/mrc-aim/phd-... for details

Check out the latest Microbiology Primer on using TraDIS to link genotype to phenotype www.microbiologyresearch.org/content/micr...

If you are looking for an AMR-themed PhD project and want to learn cool techniques such as microscopy and chemical genetics, come join my lab at Newcastle University. This project is a close collaboration with Manuel Banzhaf (Newcastle) and Gary Sharples (Durham). www.findaphd.com/phds/project...

I'm recruiting PhD students for Oct 24 start at University of Bath. Fully funded for UK students only. If interested in developing data structures/algorithms for bacterial genomics, or exploring plasmid epidemiology, or ML/AI on bacterial/phage geno/pheno data, give me a call!

The evolution and international spread of extensively drug resistant Shigella sonnei. The international outbreak (England, France, Belgium, USA, Australia) was ciprofloxacin, azithromycin, and ceftriaxone resistant - three of four WHO recommended antibiotic treatment options for shigellosis. 🖥️🧪🧬🦠🧫

We're hiring a senior bioinformatician. Come and work with us bit.ly/mmm_sbio

New in Science with @jaescudero.bsky.social . A combinatorially complete fitness landscape with >260.000 E.coli genotypes shows unexpected properties. Despite ~500 fitness peaks in this landscape, adaptive evolution can easily navigate to highest fitness peaks www.science.org/doi/10.1126/...

Thanks @scousemicrobe.bsky.social for the code! 🤗 Looking forward to joining the science community here and connecting with people who have moved over!