Long-read sequencing of Mycobacterial tuberculosis is comparable to short-read sequencing for antimicrobial resistance prediction and epidemiological studies. https://www.biorxiv.org/content/10.64898/2026.04.08.717216v1

Somehow I missed this on #WorldTBDay earlier in the week but it is so good I have to repost it. Check out this comic on “A World without Tuberculosis” bobthesquirrel.art/copy-of-un-m...

On #WorldTBDay, it’s important to reflect on the scale of the challenge we’re facing. In 2024 alone, tuberculosis (TB) caused 1.23 million deaths worldwide, remaining the leading cause of death from a single infectious agent, according to WHO @ndm.ox.ac.uk

@wvschaik.bsky.social introducing the Black Knight model for identifying ARGs at #AMR2026. A defining moment or at least an excellent use of a Monty Python analogy. The field needs more off the wall thoughtful comments!

Since 2017 the CRyPTIC project collected and collated 53,897 clinical TB samples with genetics and drug susceptibility testing data. You can download the datasets via crypticproject.info and v4.0.0 will appear later this year. #WorldTBDay @modmedmicro.bsky.social

@zaminiqbal.bsky.social giving an uplifting talk at #AMR2026. As ever he makes me think. 🤔

#AMR2026 about to kick off at the #wellcome genome campus! Got here a bit early so went to visit the new Thornton Building.

Rare opportunity to apply to become a President of Oxford’s newest college! www.nature.com/naturecareer...

I saw @reduced.bsky.social at the Rep in Bham when I was 17 in 1993. Took my daughters to see the same in Chipping Norton today. Better than I remember it. And my eldest is? 17

20 years ago today I started as a Postdoc at @ox.ac.uk on a six month contract and somehow am still here! 🤯🥳

Our team wore blue for World Antimicrobial Awareness Week 2025💙 Research into how resistance emerges, spreads and can be prevented is vital. Our group works to understand these processes and develop better tools to detect, monitor and combat antimicrobial resistance. #WAAW @oxfordbrc.bsky.social

For #WorldAntimicrobialAwarenessWeek, we introduce our recent paper on antibiotic-resistant subpopulations in TB. TB may be one of humanity’s oldest diseases, yet it still kills over 1M people yearly. As resistance spreads, knowing each patient’s resistance profile before treatment is vital. 🧬💊

Antimicrobial resistance occurs when bacteria, viruses, fungi & parasites change over time - leading to medicines being less effective against them. Here you see bacteria growing and antibiotics (the small discs) which kill the bacteria...unless they are resistant! #WAAW #AMR @oxfordbrc.bsky.social

Are you interested in infections, the micro-organisms that cause them and antimicrobial resistance? So are @bashthebug.net and they're looking for new members to join their patient & public group. More info: bashthebug.net/lay-represen... Deadline 27 Nov @ouhospitals.bsky.social @medsci.ox.ac.uk

New paper by @vbrunner.bsky.social looking at detecting rifampicin resistant subpopulations in M. tuberculosis infections using genetics and putting a lower limit on the proportion that arose due to secondary infections. bit.ly/47rwf42 @modmedmicro.bsky.social @oxfordbrc.bsky.social

Pleased to see this pre-printed, highlighting the completeness/accuracy of @nanoporetech.com long-read genome assembly for clinical Enterobacterales: www.biorxiv.org/content/10.1... Thanks to colleagues @modmedmicro.bsky.social, @ukhsa.bsky.social, @genewiz.bsky.social and @oxfordbrc.bsky.social!

Great new work from #DotNagy @modmedmicro.bsky.social - she tool 96 clinical isolates from the NEKSUS study and sequenced with both Illumina and Nanopore - question was, can we do away with hybrid sequencing for the rest of the study? www.biorxiv.org/content/10.1...

'Linking life expectancy to the bacteria in our gut: A final year undergraduate project'. Akika investigated how the gut microbiome influences longevity, with fieldwork in Nagano, Japan—home to the country’s longest-living population. Read the blog post here ➡️ bashthebug.net/2025/08/22/l...

Bit over 24 hours left to apply for these two posts to help us develop pipelines to process pathogens..! Senior Bioinformatic Engineer bit.ly/4ecl0hF Senior Biostatistical Researcher bit.ly/4kRfZxI Grade 8 or 7, depending on experience closing date: noon Tues 8 July

Mind That Cyclist! Give Him Room 1950 Artist: Roland Davies

Job advert to come and work with me on tuberculosis closes tomorrow (Friday) at noon! Part of #OxCOD4TB bit.ly/4ndKOhF @ndm.ox.ac.uk @modmedmicro.bsky.social @oxfordbrc.bsky.social

Congratulations to the winners of the poster prizes, Elliott Rogers and Iva Grujic, yesterday at the 3rd #Dx4LMIC conference at @reubencollege.bsky.social !

Andrew Singer gets day two underway at the #Dx4LMICs conference at @reubencollege.bsky.social

Lionel Tarassenko introducing Vivian Lee who is giving the after dinner speech at #Dx4LMICs conference at @reubencollege.bsky.social

Jospeth Matovu: HIV self testing among fishermen @reubencollege.bsky.social #Dx4LMICs

Arjuna Sen talking about equity in epilepsy at @reubencollege.bsky.social #Dx4LMICs

@gariclifford.bsky.social talking about how extensive cell phone coverage was in China 20 years ago: “If you can drive a truck up a road there will be a cell phone tower at the end of it” #Dx4LMICs @reubencollege.bsky.social

Joshua Kibera gets us underway at #DxLMICs at @reubencollege.bsky.social

Any questions DM me

All ready for day one of the third #Dx4LMICs conference at @reubencollege.bsky.social !

Thanks for the reminder @janemunday.bsky.social. Every summer, I repost this article DROWNING DOES NOT LOOK LIKE DROWNING. To date, I know of FOUR kids who were saved after someone who'd clicked on the link learnt how to spot actual drowning. Take time to read and pass on. slate.com/technology/2...

And that's a wrap on #ESM2025! A huge thank you to our incredible community of scientists, speakers, and organizers who made this week unforgettable. The future of mycobacteriology is bright! See you all in 2026! 👋 #Tuberculosis #Science

Three posts all closing next week! Senior Biostatistical Researcher bit.ly/4kRfZxI Senior Bioinformatic Engineer bit.ly/4ecl0hF both Grade 8 or 7, closing noon Wed 2 Jul Computational Mycobacteriologist Grade 7, closing noon Fri 4 Jul bit.ly/4ndKOhF @medsci.ox.ac.uk

[TRAILER]🎥 “The Clinic That Crossed the River” is a film by young men from Xhora Mouth, Bulungula in the Eastern Cape. This film tells a story of the Bulungula community and their long, difficult journey to access healthcare. Check link for more: youtube.com/watch?v=Igh7...

Come and work with me and use the 53,897 samples of M. tuberculosis we have collated to help tackle this important disease! We are part of the OxCoD4TB consortium that is developing new therapeutics for tuberculosis. Grade 7, funding until 28 Feb 2028, deadline noon Fri 4 July bit.ly/4ndKOhF

@vbrunner.bsky.social doing her pitch for her poster at #ESMyco! @modmedmicro.bsky.social

The relaunch of crypticproject.info at #ESMyco by @philipwfowler.bsky.social 53,897 clinical tuberculosis samples with genetics and drug susceptibility testing data!

Just like buses, here is a third role we are advertising for! Come and help @philipwfowler.bsky.social use the large TB datasets we hold to help the OxCoD4TB consortium develop new therapeutics for tuberculosis. Grade 7, funding until 28 Feb 2028, deadline noon Fri 4 July bit.ly/4ndKOhF

Come and help us develop and validate genetic pipelines for processing pathogens in collaboration with @eitoxford.bsky.social Senior Bioinformatic Engineer bit.ly/4ecl0hF Senior Biostatistical Researcher bit.ly/4kRfZxI Grade 8 or 7, depending on experience closing date: noon Wednesday 2 July

Start of #ESMyco - my fourth meeting and this is one of my favourites!

Come and help us develop and validate genetic pipelines for processing pathogens in collaboration with @eitoxford.bsky.social Senior Bioinformatic Engineer bit.ly/4ecl0hF Senior Biostatistical Researcher bit.ly/4kRfZxI Grade 8 or 7, depending on experience closing date: noon Wednesday 2 July

Lots of bugs at the @oxfordbrc.bsky.social showcase in the Westgate!

Come and find @modmedmicro.bsky.social at the Westgate in Oxford as part of the @oxfordbrc.bsky.social showcase!

Come and play our dance mat game named after me! Outside John Lewis in the Westgate as part of the @oxfordbrc.bsky.social showcase!

First time the OxCoD4TB team has met up!

Kevin Yuan talking now at #ESCMIDGlobal in Hall 9!

And on the last day of #ESCMIDGlobal we have 1406 Hall 9 - Kevin Yuan P3166 - Dot Nagy

ModMedMicro at #ESCMIDGlobal (well nearly everyone!)

Dylan Adlard, Jeremy Westhead and me presenting posters in the huge hall at #ESCMIDGlobal