Andrew Millard
@milja001.bsky.social
📤 726
📥 159
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phage, genomes & random news items. All views my own millardlab.org
reposted by
Andrew Millard
Professor Lesley Hoyles
about 2 months ago
If you are UK-based and working on any aspect of microbiomes (human, plant, insect, soil, animal, ...), please do sign up to Microbiome-Net for details of networking, funding and training opportunities.
forms.office.com/pages/respon...
add a skeleton here at some point
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Got an email to say your manuscript had failed manuscripts checks as the corresponding author email was missing and is required ... I am the corresponding author 🤔..
3 months ago
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After a busy period ,
@ryancook94.bsky.social
and I have have updated links to latest INPHARED dataset. With 37.5K genomes now. If some "iffy" genomes have got thought the automated and then out manual filters. Let us know the accession numbers so we can exclude
millardlab.org/bacteriophage-…
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https://millardlab.org/bacteriophage-…
3 months ago
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reposted by
Andrew Millard
Lucy Evans 🧫🦠👩🏻🔬
5 months ago
Submitted my first set of annual review stuff for my PhD (yes I started end of September but the annual review is due 1st June) and looking back on the past 8 months... Wow I have grown into even more of a badass girlie 😎🧪
#phd
#microsky
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reposted by
Andrew Millard
Adam Blanchard
5 months ago
New preprint up on the changes in the bovine virome though different life stages led by
@milja001.bsky.social
@ryancook94.bsky.social
www.biorxiv.org/content/10.1...
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Life-Stage Transitions Drive Distinct Gut Viral Communities in Dairy Cattle
Ruminant gut microbial communities profoundly influence host health and environmental impacts, yet their viral components remain poorly characterised across developmental transitions. Here, we analyse...
https://www.biorxiv.org/content/10.1101/2025.05.24.655612v1
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reposted by
Andrew Millard
Ryan Cook
6 months ago
This is probably my last piece of work from my
@medresfdn.bsky.social
funded PhD at
@uniofnottingham.bsky.social
(thanks for all the support over the years!). Contributions from
@milja001.bsky.social
@evelienadri.bsky.social
(and many others not yet on Bluesky) 13/13
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reposted by
Andrew Millard
Ryan Cook
6 months ago
The dairy cow gut virome is a dynamic ecosystem that could be an under-studied player in sustainable agriculture 🔑 Preprint:
www.biorxiv.org/content/10.1...
#Microbiome
#Virome
#ClimateScience
#Agriculture
#Dairy
#Cows
#Methanogens
12/13
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Life-Stage Transitions Drive Distinct Gut Viral Communities in Dairy Cattle
Ruminant gut microbial communities profoundly influence host health and environmental impacts, yet their viral components remain poorly characterised across developmental transitions. Here, we analyse...
https://www.biorxiv.org/content/10.1101/2025.05.24.655612v1
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reposted by
Andrew Millard
Ryan Cook
6 months ago
1,338 vOTUs were predicted complete.
@milja001.bsky.social
and I agreed to manually inspect the annotations of every single one. I started at the top, he started at the bottom (I think he only did 50 though despite agreeing to do half 💁♂️). All of them looked viral in origin, and most were novel 4/13
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reposted by
Andrew Millard
Ryan Cook
6 months ago
We profiled the faecal virome of dairy cows across key life stages with ultra-deep Nanopore and Illumina sequencing 🐮 We recovered over 30,000 vOTUs (approximate to species), and included shallow bulk metagenomes for each sample to place the viruses within the context of their microbial hosts 3/13
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reposted by
Andrew Millard
Ryan Cook
6 months ago
Why does this matter? Dairy cows = 265 million worldwide, huge importance in food production and greenhouse gas emissions. Yet we know very little about their gut viral communities across key life stages 🐄 2/13
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reposted by
Andrew Millard
Ryan Cook
6 months ago
🧬🐄 NEW PREPRINT: Really happy to finally share the last big piece of work from my PhD! Spoiler: Cows are great and so are their viromes 🧵1/13
www.biorxiv.org/content/10.1...
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Life-Stage Transitions Drive Distinct Gut Viral Communities in Dairy Cattle
Ruminant gut microbial communities profoundly influence host health and environmental impacts, yet their viral components remain poorly characterised across developmental transitions. Here, we analyse...
https://www.biorxiv.org/content/10.1101/2025.05.24.655612v1
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Interested in phages ? Want to work as team that will isolate, genome sequence and charachterise 1000s of phage to build a biobank . Come work with me and Martha Clokie at Leicester
jobs.le.ac.uk/vacancies/va...
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Vacancy Search Results - University of Leicester Recruitment Team
View our Latest Vacancies
https://jobs.le.ac.uk/vacancies/vacancy-search-results.aspx
6 months ago
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Take away coffees are served differently in Vietnam..bit fancier than standard Costa slop ,😁
6 months ago
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www.biorxiv.org/content/10.1...
Searching for lytic phages in bacterial genome assemblies ..!
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Hidden in plain sight: Bacterial genomes reveal thousands of lytic phages with therapeutic potential
Phages are typically classified as temperate, integrating into host genomes, or lytic, replicating and killing bacteria. Lytic phages are not expected in bacterial genome sequences, yet our analysis o...
https://www.biorxiv.org/content/10.1101/2025.05.06.652010v1
6 months ago
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We
@ryancook94.bsky.social
, updated number of phage genomes we can find in NCBI .... Took longer than it should to do this months ...
millardlab.org/home/bacteriop…
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https://millardlab.org/home/bacteriop…
7 months ago
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reposted by
Andrew Millard
Antonia Sagona
7 months ago
Many congratulations to Mickey
@mickey-tad.bsky.social
for successfully defending his viva today!! My warmest thanks to Andy
@milja001.bsky.social
and Lona Alkhalaf for being his examiners and to
@nezislab.bsky.social
for serving as Exam Advisor!
@warwicklifesci.bsky.social
@albertilab.bsky.social
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reposted by
Andrew Millard
Branko Rihtman
8 months ago
Job claxon! Senior postdoc research associate position at the Becky Mayer Centre for Phage Research at the University of Leicester, working with
@milja001.bsky.social
and Martha Clokie. Brilliant opportunity!
jobs.le.ac.uk/vacancies/11...
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Senior Post Doctoral Research Associate– Protein Lead in Leicester | University of Leicester Recruitment Team
View details and apply for this Senior Post Doctoral Research Associate– Protein Lead vacancy in Leicester. You will lead an independent research project within the Becky Mayer Centre for Pha...
https://jobs.le.ac.uk/vacancies/11536/senior-post-doctoral-research-associate-protein-lead.html
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taxMyPhage made Jans pick...in this month's Capsid and tail ..
phage.directory
ptax.ku.dk
github.com/amillard/tax_m…
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Phage Directory
Phage Directory curates a database of phage labs, phages, and host strains to advance research and phage therapy.
https://phage.directory
8 months ago
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we (
@ryancook94.bsky.social
) updated genomes in INPHARED
millardlab.org/phage-genomes-…
There are more genomes than last month! Shocker. Haven't had a chance to analyse yet
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https://millardlab.org/phage-genomes-…
8 months ago
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Great to have you involved
@remidenise.bsky.social
.might even meet in person at some point :-)
add a skeleton here at some point
8 months ago
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reposted by
Andrew Millard
Ellie Jameson
9 months ago
Phage taxonomy doesn’t have to be taxing, my latest cartoon for the Phage journal. To illustrate 𝘁𝗮𝘅𝗠𝘆𝗣𝗵𝗮𝗴𝗲
lnkd.in/dAXK4sSt
@milja001.bsky.social
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reposted by
Andrew Millard
Krishna Sanjay Chellappa
10 months ago
Found a lot of use through phage genomics workshop hosted by
@milja001.bsky.social
and it was great learning so much from his genomic pipelines. Lots to learn for me in this field, and very complimentary to my work done in the labs (and scraping alpaca poop for phage isolations!)
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reposted by
Andrew Millard
Ryan Cook
10 months ago
And I finally got round to updating the GitHub links...
github.com/RyanCook94/i...
add a skeleton here at some point
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reposted by
Andrew Millard
Ryan Cook
11 months ago
First update of the Bluesky era!
#PhageSky
add a skeleton here at some point
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New year ... new lot of genomes. With
@ryancook94.bsky.social
updated what we can find in Genbank
millardlab.org/phage-genome-j…
With entire set annotated with PHROGs millardlab-inphared.s3.climb.ac.uk/GenomesDB_Jan2…
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https://millardlab.org/phage-genome-j…
10 months ago
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reposted by
Andrew Millard
Ryan Wick
10 months ago
New year, new assemblies! I'm excited to announce Autocycler, my new tool for consensus assembly of long-read bacterial genomes! It's the successor to Trycycler, designed to be faster and less reliant on user intervention. Check it out:
github.com/rrwick/Autoc...
(1/5)
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Home
A tool for generating consensus long-read assemblies for bacterial genomes - rrwick/Autocycler
https://github.com/rrwick/Autocycler/wiki
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reposted by
Andrew Millard
Julia Willett
11 months ago
Published just in time for the holidays! I learned so much while writing about the past, present, and future of E. faecalis research with Gary. Check it out! 🦠🧫🧪🔬
journals.asm.org/doi/10.1128/...
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Insights into ecology, pathogenesis, and biofilm formation of Enterococcus faecalis from functional genomics | Microbiology and Molecular Biology Reviews
SUMMARYEnterococcus faecalis is a significant resident of the gastrointestinal tract of most animals, including humans. Although generally non-pathogenic in healthy hosts, this microbe is adept at the exploitation of compromises in host immune functions, ...
https://journals.asm.org/doi/10.1128/mmbr.00081-23
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reposted by
Andrew Millard
Phage papers
11 months ago
Isolation, characterization, and genomic analysis of BUCT627: a lytic bacteriophage targeting Stenotrophomonas maltophilia. DOI: 10.1093/femsle/fnae076 https://pubmed.ncbi.nlm.nih.gov/39349986/
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Isolation, characterization, and genomic analysis of BUCT627: a lytic bacteriophage targeting Stenotrophomonas maltophilia - PubMed
Stenotrophomonas infections pose significant therapeutic challenges due to escalating resistance to antibiotics and chemotherapeutic agents. Phages offer a potential solution by virtue of their specific bacterial targeting capabilities. In this study, we isolated a new Stenotrophomonas bacteriophage …
https://pubmed.ncbi.nlm.nih.gov/39349986/
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We are getting a new name and a £4 Million donation . Thanks to Jimmy Mayer, we will become the " Becky Mayer Centre for Phage Research "
le.ac.uk/news/2024/de...
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Pioneering centre receives £4 million boost | News | University of Leicester
https://le.ac.uk/news/2024/december/phage-donation
11 months ago
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We (
@ryancook94.bsky.social
) updated number complete phage genomes we can find in Genbank. downloads and links on
millardlab.org/phage-genomes-…
11 months ago
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We updated complete genomes we can find in Genbank . Big increase this month with lots of new Microviridae from what looks like a single study . All links on
millardlab.org/phages-genomes…
an
d github.com/RyanCook94/inp
to download latest data
12 months ago
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reposted by
Andrew Millard
Paul Hoskisson 🧫 🦠🐸
over 1 year ago
Two Post-Doc positions in my group in collaboration with Claudio Avignone-Rossa & GSK using
#engineeringbiology
to improve
#sustainability
of industrial
#Streptomyces
fermentations
strathvacancies.engageats.co.uk/Vacancies/W/...
pls RT-happy to chat MicrobioSoc conference next wk,reach out by email
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Research Associates x 2 posts (606597)
https://strathvacancies.engageats.co.uk/Vacancies/W/1496/0/425029/15019/research-associates-x-2-posts-606597
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reposted by
Andrew Millard
Bede Constantinides
almost 2 years ago
Hostile 1.0.0 released and live on Bioconda - Adds human genomes masked against bacteria, viruses and phage (thanks for phage genomes
@milja001.bsky.social
!) - Improved automatic index download - Improved genome masking - Bug fixes
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GitHub - bede/hostile: Accurate host read removal
Accurate host read removal. Contribute to bede/hostile development by creating an account on GitHub.
https://github.com/bede/hostile
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reposted by
Andrew Millard
Professor Lesley Hoyles
almost 2 years ago
Christina Hazard gave us a great talk on this work a few weeks ago. Really nice study.
add a skeleton here at some point
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reposted by
Andrew Millard
Willem van Schaik
almost 2 years ago
New PhD position in the MRC Doctoral Training Programme for an Oct 2024 start with
@milja001.bsky.social
and myself as supervisors. The gut phageome as a driver for microbiome dynamics in critically ill patients Scroll down on
more.bham.ac.uk/mrc-aim/phd-...
for details
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