We invite you to explore the preliminary program for @CellSymposia #CSMito2026 and consider joining us in Glasgow, Scotland, June 21–23, 2026 for what promises to be an engaging and interdisciplinary meeting. 🔗 http://dlvr.it/TQMpPG

Have you ever wondered how many N-Glycans or #glycoproteins there are on cells? The numbers are massive: calculations suggest about 20 to 200 million N-glycans per human cell! Read the full blog post: research.bidmc.org/ncfg/blog/24... #glycobiology #glycotime #cells #biology

Exciting new preprint on oxytocin neural circuits for massage led by Manon Bohic in Vicky Abraira’s lab. Sasha and I were glad to contribute imaging experiments to this collaborative effort, spanning mice to humans. Vicky is a master at bringing people together. www.biorxiv.org/content/10.6...

🧠⚡️💊New @nature.com publication ! Mimicking opioid analgesia in cortical pain circuits We built a brain-behavior framework to decode spontaneous chronic pain in mice—and to biologically mimic morphine with a synthetic opioid gene therapy nature.com/articles/s41... @pennmedicine.bsky.social

I've been waiting for this Titeca et al. story from Anne-Claude Gavin's lab to come out: A systematic, comprehensive analysis of lipid transfer protein cargo selection, a truly massive undertaking. What a time to work in lipid biology. Cool stuff every few days. www.nature.com/articles/s41...

Happy new year! I've so enjoyed the end-of-year lists of people's favorite papers from 2025, so I made a list of 16 #lipidtime studies from 2025 that I found interesting. Here they are in no particular order (please add more if you would like!), and here's to much more exciting science in 2026! 🧪

To all lipid-curious cell biologists: check out this comprehensive overview of lipid-based methods by @gerryhammond.bsky.social and colleagues in @jcb.org — a school of Babel fish for #lipidtime: rupress.org/jcb/article/...

Check out our new work! In collaboration with @moitrayee-lab.bsky.social lab at Yale!

Organelles do NOT have a single uniform pH. And if you think they must, because “protons diffuse fast,” this paper is for you. A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

A preprint from my lab @yalepharm.bsky.social: doi.org/10.1101/2025... show molecular mechanisms of uncoupling nociceptive and neurotrophic TrkA signaling, using #singleMolecule #microscopy, #cryoEM, #electrophysiology, #signaling, offering a clear blueprint to target this long sought-after pathway!

Super cool! Congratulations!

Join us in welcoming our next 2025–2026 Pharmacology Seminar Series speaker: our very own Dr. Moi Bhattacharyya! She will be presenting her work at 12 pm on Thursday, November 20th in the Brady Auditorium.

1/🚨 New preprint out!🚨 We uncovered that #PI3K-driven wild-type RAS activation bypasses #KRAS inhibition in pancreatic adenocarcinoma (#PDAC) to drive #resistance. 🔑PI3K isn’t just a downstream RAS effector – it can be an upstream RAS regulator. 📄 www.biorxiv.org/content/10.1...

Excited to attend and speak at the GRC grc.org/neurotrophic-m… about our work on NGF receptor TrkA @yalepharm.bsky.social @yaleschoolofmed.bsky.social! Dr. Shailesh Kumar from my lab is also presenting a poster. Looking forward to hearing about cool new discoveries in the area!

Thank you @hypothesisfund.bsky.social and @krishnanyamuna.bsky.social for this opportunity to shed ‘light’ on membrane contacts! Honored to be part of this and congratulations to my fellow awardees. Can’t wait to start this scientific adventure @yalepharm.bsky.social @yaleschoolofmed.bsky.social!

Very excited to host Dr. Stephen Sligar this Thursday! Anyone doing membrane protein biophysics will immediately recognize his immense contributions in enabling reconstitution of membrane proteins in lipid nanodiscs and subsequent applications! Hope to see many of you there!

ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🍬🍭🔬 For the first time, we’re able to study the molecular architecture of the glycocalyx at single-sugar resolution—a longstanding challenge in glycobiology! #glycotime Preprint and #bluetorial below!!

I am excited to host @eboyden3.bsky.social for a seminar in @yalepharm.bsky.social on Thursday, Feb 13. I hope to see many of you there!

@fda.govFDA Approves Novel Non-Opioid Treatment for Moderate to Severe Acute Pain www.fda.gov/news-events/...

Every once in a while we publish a paper that moves a whole field forward. I think that's the case for this one from the Bugaj lab, where they describe proteins for THERMOGENETIC control of cellular behavior. www.nature.com/articles/s41...

Amazing new work from the lab of @aliceyting.bsky.social @stanfordmedicine.bsky.social @stanfordbiosci.bsky.social, engineered GPCRs for ligand-activated cell responses www.nature.com/articles/s41...

Book rec: Neanderthal Man by 2022 @nobelprize.bsky.social laureate Svante Pääbo. A fascinating dive into sequencing ancient 🧬. Captures the thrills, setbacks, and Pääbo’s personal vulnerabilities during groundbreaking science.