Happy to share our new review of structural and biophysical mechanisms of cytoskeletal force transduction: doi.org/10.1146/annu...

Happy #FluorescenceFriday! I captured this shot of a group of embryonic macrophages expressing LifeAct and H2B migrating inside tissue. These cells can use lamellipodia, filopodia, or blebs to migrate, and are frequently switching between these different modes or combining them. So fascinating.

Interdisciplinary course on Artificial Cells next fall in Paris. Registrations are open : www.edu.bio.ens.psl.eu/spip.php?art... For masters, PhD students and postdocs. Every wednesday, 5 to 7 PM, @espciparispsl.bsky.social from September to December. See below for the list of great teachers!

💥 🚀 New preprint! 🎉🥳 How do hundreds of organelles organize themselves into near-perfect patterns inside a cell, without a blueprint? We dive deep into how basal bodies (BBs) self-organize in MCCs - and how actin actively tunes their dynamics into order 🍪 🧵👇 (1/17)

A new Profile is now published in #CYTOSKELETON!!! "Foundational Discoveries in #Actin Regulation: An Interview With Tom Pollard". This is a must read for all actin fans. Huge thanks to Alfred Chin and @evakarasmanis.bsky.social for putting this together. onlinelibrary.wiley.com/doi/10.1002/...

Multinucleate cells challenge deeply-held assumptions about complexity, ecological success and evolution. Postdoc extraordinaire and gifted writer @mrosjac.bsky.social tackles this subject with aplomb - tell us what you think! www.sciencedirect.com/science/arti... @currentbiology.bsky.social

The "Blanchoin cell" @lblanchoin.bsky.social has crawled into the @planetvie.bsky.social website, a free French resource for teaching biology hosted by @normalesup.bsky.social: planet-vie.ens.fr/thematiques/...

Ready for #CellLaVie2026? Program & registration are live! Join us Oct 21–23, 2026 at Institut Pasteur, Paris, for multidisciplinary cell biology, imaging, talks, posters & outreach, w/ Manuel Théry's behind-the-scenes look at the Musée d’Orsay video-mapping project. www.atoutcom.com/cell-la-vie/

Very pleased that after a rigorous (and lengthy) review process, our paper visualizing how myosin generated forces modulate actin filament structure for mechanosensitive recogntion by α-catenin has appeared in @nature.com : www.nature.com/articles/s41...

How can a single cell learn without a brain? We explore this in my paper with @wallaceucsf.bsky.social! We discovered that single cells may learn using molecules similar to those that animal brains use to learn, like CaMKII. Cells can also propagate memory states to their progeny!

Photosynthetic bacteria helped shape Planet Earth. Among them cyanobacteria—microbes that produced the oxygen in Earth’s atmosphere & made complex life possible. They have captivated scientists for decades by offering insights into how life evolved from single cells into multicellular organisms.

🔥Just out in @science.org Magazine 🔥 Our work on the emergent behavior of active polar rods is now online! www.science.org/doi/10.1126/... 🌟 Even more exciting: the work is featured on the cover

🧫 Et si la science devenait une œuvre d’art ? Au @museeorsay.bsky.social, des images de cellules observées au microscope deviennent une performance visuelle pour faire sortir la biologie du laboratoire et révéler l’architecture du vivant. 🎥 www.youtube.com/watch?v=TNQM...

You are finishing your PhD and looking to continue in science? The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro.... Thanks for reposting!

Cytoskeleton enthusiasts: join us for the Cytoskeletal Motors GRC, July 12-17, 2026, in Portland Maine. Abstracts submitted by April 5 will be considered for short talks. Please apply! bit.ly/4cWxvzj

Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating). A brief 🧵 (carried over from the old place)

As independent tests, we also combined cells stained with distinct fluorophores, and found they aggregated into chimeric colonies. We also showed multicellular development was not abolished by cell cycle inhibitors. Thus our fear became a finding: C. flexa can aggregate.

An actin-labeled cell line happily dividing courtesy of NeuroCyto CRISPR wizard @nicolasjullien.bsky.social (🔬 multi-point 20-hour acquisition, 5 min framerate) 🧪

#ResultatScientifique🔎| Comment les cellules végétales orientent-elles correctement leur division pour construire des tissus cohérents ? ✍️ @mc-caillaud.bsky.social @camilagoldy.bsky.social ▶️ buff.ly/JWEIPoD buff.ly/Joa0GPo

Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de

Happy to highlight our collaborative work from our @ijmonod.bsky.social team with @destriano.bsky.social, B. Goyeau and M. Chabanon. Cytoplasmic crowding acts as a porous medium that hinders macromolecular diffusivity. Plus: a clever way to measure cell volume. www.pnas.org/doi/10.1073/...

A few seconds of eternity: From microscope to museum❣️ It was truly delightful to be part of this project, celebrating life as a continuous dance of creation, collapse, and renewal. 🔄 Kudos to @manuelthery.bsky.social @lblanchoin.bsky.social #cytomorpholab members, and @museeorsay.bsky.social

We spend way too much time manually analyzing #microtubules 🔬 Together with Mario, Justus, Dominik, Felix & Erik we used synthetic data and foundation models to build a fully automated segmentation pipeline.
 #microscopy, #imageanalysis & #AI Check out our preprint: www.biorxiv.org/content/10.6...

My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!

📣 #Job alert! Looking to establish your own independent research in cell biology, development or evo-devo? The @cnrs.fr is recruiting 7 scientists in that area of research. Here are updated unofficial guidelines. Reach out to members of the committee if you have questions c3n-cn.fr/section-24-w...

Le CNRS a proposé au Sénat des mesures fortes pour renforcer la place des femmes en science. Cette sous-représentation n’est pas une fatalité : elle résulte de biais, de stéréotypes, d’inégalités et de violences tout au long des parcours scolaires et professionnels.

#Communiqué 🗞️ En 2026, pour célébrer ses 40 ans, le @museeorsay.bsky.social devient un véritable théâtre du vivant. Deux soirées dans la Nef plongeront le public dans un spectacle immersif au coeur des dynamiques cellulaires donnant vie à l’architecture de la gare. 👉 www.cnrs.fr/fr/presse/un...

👉Excited to share our latest work @natmicrobiol.nature.com, revealing a decrease in cytoplasmic crowding during filamentous growth in the human fungal pathogen Candida albicans. Furthermore we found that inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen rdcu.be/eT1Su

🚨 Je cherche des chercheur-ses de toutes disciplines pour un doc radio pour parler de leur sujet de recherche mais aussi de leur quotidien (une journée type au labo). Contrainte supplémentaire, le labo doit être hors de Paris. Plus d'infos : forms.gle/hw9wH2p5UH4A...

Cells can hunt prey, solve mazes, and learn from past experience. Does this mean they can think, at some level? Find out more at our upcoming session on "Cell Behavior and Cognition" at the ASCB/EMBO #cellbio2025 meeting, Saturday 1-3 pm rm 115.

#RésultatScientifique 🔎 | Comment les filaments d'actine s'organisent à l'intérieur des cellules et des tissus vivants 🔬 @institutfresnel.bsky.social 🤝 @univ-amu.fr @centralemed.bsky.social @cnrs.fr 📍 @cnrs-dr12.bsky.social

is there a direct crosstalk between actin and vimentin intermediate filaments? Our work shows that vimentin promotes actin assembly by stabilizing ATP-subunits at the barbed end. Fantastic work done by @lilianpaty.bsky.social with @romet-jegou-lab.bsky.social www.biorxiv.org/content/10.1...

⚡Ready to grow and be inspired as a scientist? We’re looking for a *PhD student* to join our lab at @crg.eu in Barcelona and explore how cells self-organize, uncovering life’s inner design💡 We offer strong mentoring, cutting-edge science, and a vibrant international team🌍 Check the link below!

Very excited that my final postdoctoral work is now online in Cell @cellpress.bsky.social. www.sciencedirect.com/science/arti... Using 16 (!) cryo-EM structures, we uncovered how the three proteins coronin, cofilin and AIP1 work together to rapidly disassemble actin filaments.

Live on Oct 7, the MBoC 2025 Early Career Award Webinar (Part 1) runs 12–1 pm ET. > Keynote: Margaret Gardel (UChicago) > lightning talks from UCSF, UVM, ETH Zurich, Cambridge & Harvard > moderation by John Aitchison Free to attend → www.ascb.org/ascb-meeting... #ASCB #CellBiology

”Please inhibit responsibly: Natural and synthetic actin toxins as useful tools in cell biology” I had a lot of fun going down different actin inhibitor rabbit holes with @onishilab.bsky.social on this perspective! www.molbiolcell.org/doi/10.1091/... www.molbiolcell.org/cms/10.1091/...

We’re organizing a conference at @ijmonod.bsky.social in Paris, January 2026, in memory of M.P. Sheetz — pioneer in cell mechanics and mechanobiology, co-discoverer of kinesin, and founder of @mbisg.bsky.social. Join us to explore his legacy. mikeinmemoriam.sciencesconf.org

Allocation of resources among multiple daughter cells. New study from Alison Wirshing, Daniel Lew and colleagues @mit.edu: rupress.org/jcb/article/... #Cytoskeleton #Development

New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵

Which city is the best for Cytoskeleton research? Dresden? Barcelona? Cambridge ? Noooo ... you all know its Paris, right? 😎 Registering to the annual meeting on Friday 14th of November is now open: pcd2025.sciencesconf.org Keynote speeches by @carter-lab.bsky.social and Verena Ruprecht !

A new #UExM probe for #Actin! Fun times thinking/developing/testing with @centriolelab.bsky.social & @lreymond.bsky.social ! Congrats to all ! If interested in #UExM, or #HAK-Actin, feel free to reach out ! Soon available at @spirochrome.com #Expansion #Microscopy #ProtistsOnSky

🌱✂️ How do plant cells decide where to divide? Our work shows that actin can override the geometric rules—guiding cells to divide in alternative orientations. #PlantScience #CellBiology #Arabidopsis @camilagoldy.bsky.social @rdplab.bsky.social www.biorxiv.org/content/10.1...

Microtubules: the architect of muscles. Watch how microtubules transport mitochondria in proximity to energy consuming sarcomeres in muscles of flies and mice. @jeromeavellaneda.bsky.social @nunoluis.bsky.social @ibdm.bsky.social with @gomeslabo.bsky.social www.sciencedirect.com/science/arti...

We have used many microwells to confine biochemical reactions in our recent studies. We wanted to share the protocol for preparing and characterizing microwells; this protocol is now published here : www.frontiersin.org/journals/cel... @manuelthery.bsky.social @lblanchoin.bsky.social

#science 🧬 | Non, ce ne sont ni les slips de Superman, ni ceux de Walter White dans Breaking Bad. C’est une cellule ... et la même photographiée 36 fois. Sensation, adaptation, mémoire… la cellule est plus futée qu’on ne le croit 🤯. Pour en savoir plus 👉 youtu.be/dX4rDXLJAdI

We have used many microwells to confine biochemical reactions in our recent studies. We wanted to share the protocol for preparing and characterizing microwells; this protocol is now published here : www.frontiersin.org/journals/cel... @manuelthery.bsky.social @lblanchoin.bsky.social

🔬 From JCB’s July issue (rupress.org/jcb/issue/22...): a PtK2 cell plated on a micropattern and injected with low doses of soluble actin (orange) and tubulin (blue) in order to generate speckles along the corresponding filaments. From @manuelthery.bsky.social group (rupress.org/jcb/article/...).

this focused issue includes a great method by @alexandra-colin.bsky.social to make closed microwell in order to encapsulate your favorite reconstitution mix in compartments of controled size and shape. 🔴🟥🔻❤️

Interested in reconstitution methods? Love cell biology? Check out the accepted manuscripts in our Research Topic on Reconstitution Methods in Cell Biology! We are still open for submissions so if you're writing something exciting this summer, send it here: www.frontiersin.org/research-top...

Want to brush up your French? Check the summary of our work with @stefvass.bsky.social, “Plongée au cœur de l'endocytose axonale”, just out in the June issue of Médecine/Science! Open access here: www.medecinesciences.org/fr/articles/... And we got the cover 😎