Chen Zhang
@zchenstory.bsky.social
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📥 301
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Bacteriologist studying S-layer 🔬🦠🧬 Postdoc at Rudner lab @harvardmed. PhD alumni @epfl
"Watermelon!" this is what my 2yo son calls 😂 --bacterial biofilm photograph at Harvard museum of nature history (guess it's congo red stained and hope never appears in watermelon)
4 months ago
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anna brogan
5 months ago
Very happy to share that a large part of my thesis work is out today: B. subtilis uses the second messenger c-di-AMP to modulate its turgor pressure in response to the state of its cell envelope.
www.nature.com/articles/s41...
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Cyclic-di-AMP modulates cellular turgor in response to defects in bacterial cell wall synthesis - Nature Microbiology
Brogan et al. uncover a signalling pathway in which levels of the nucleotide second messenger c-di-AMP increase in response to defects in cell wall synthesis. This regulatory pathway decreases turgor ...
https://www.nature.com/articles/s41564-025-02027-2
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Tanmay Bharat
5 months ago
The mechanics of a continuous self-assembling surface-layer aids cell division in an archaeon out in
@pnas.org
Tight collaboration with Sherman Foo, Alice Cezanne and
@buzzbaum.bsky.social
, Sulfolobus cryo-ET from
@idocaspy.bsky.social
www.pnas.org/doi/10.1073/...
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A self-assembling surface layer flattens the cytokinetic furrow to aid cell division in an archaeon | PNAS
The surface layer or “S-layer” is a two-dimensional lattice of proteins that coats a wide range of archaea and bacteria in place of a cell wall or ...
https://www.pnas.org/doi/10.1073/pnas.2501044122
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time to admit as a REAL bacteriologist
6 months ago
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Suliana Manley
7 months ago
Our latest preprint
www.biorxiv.org/content/10.1...
, describes Willi Stepp’s project to make smart microscopy even gentler by doing event detection in phase contrast. We developed neural networks to detect mito-LD and mito-lysosome contacts, as well as mitochondrial pre-fission constrictions.
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Anjana Badrinarayanan
7 months ago
Happy to share Asha Joseph and Inchara Adhikashreni's latest work from the lab, describing replisome speed variation in Caulobacter!
www.cell.com/current-biol...
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Live tracking of replisomes reveals nutrient-dependent regulation of replication elongation rates in Caulobacter crescentus
Adhikashreni et al. use quantitative live-cell imaging to track cell-cycle dynamics in hundreds of individual bacteria. They observe nutrient-dependent regulation of replication elongation rates that ...
https://www.cell.com/current-biology/abstract/S0960-9822(25)00294-5?rss=yes
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Andrea Vettiger
7 months ago
It has been coming a long way... happy to share our latest work with you:
www.biorxiv.org/content/10.1...
Here, we show the importance of septal fortification by the Class A Penicillin Binding Protein, PBP1b, in E. coli and provide a molecular mechanism for this function. (1/12).
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The aPBP-type cell wall synthase PBP1b plays a specialized role in fortifying the Escherichia coli division site against osmotic rupture
A multi-protein system called the divisome promotes bacterial division. This apparatus synthesizes the peptidoglycan (PG) cell wall layer that forms the daughter cell poles and protects them from osmo...
https://www.biorxiv.org/content/10.1101/2025.04.02.646830v1
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Matt Lycas
7 months ago
Expansion microscopy of a tardigrade
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Super glad to be one of the awardees!
add a skeleton here at some point
7 months ago
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Mariana Pinho
7 months ago
We have 3 positions for students who want to start a PhD in the next 12 months. If you like advanced fluorescence microscopy techniques and S. aureus cell biology, check links and apply(April 4)
euraxess.ec.europa.eu/jobs/325394
euraxess.ec.europa.eu/jobs/325395
euraxess.ec.europa.eu/jobs/325396
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STCmicrobeblog
8 months ago
schaechter.asmblog.org/schaechter/2...
#MicroSky
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Wait, What? extracurricular DNA (eDNA)
by Christoph — Among biologists, DNA is a household term, the acronym for desoxyribonucleic acid, which hardly anyone pronounces in full. But can you find your way around the zoo of prefixes that are ...
https://schaechter.asmblog.org/schaechter/2025/03/wait-what-extracurricular-dna-edna.html
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Dame lab at Leiden University
9 months ago
In
@molecularmicro.bsky.social
: two special issues on Prokaryotic Chromosome Organization. Many excellent contributions, including a vision article: 'Future directions of the Prokaryotic Chromosome Field', outcome of BioPhyChrom 2023
@biophychrom.bsky.social
onlinelibrary.wiley.com/doi/10.1111/...
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Future Directions of the Prokaryotic Chromosome Field
In September 2023, the Biology and Physics of Prokaryotic Chromosomes meeting ran at the Lorentz Center in Leiden, The Netherlands. As part of the workshop, those in attendance developed a series of ....
https://onlinelibrary.wiley.com/doi/10.1111/mmi.15347
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Ed Boyden
8 months ago
Expansion microscopy (ExM) of the entire mouse body (
pubs.acs.org/doi/10.1021/...
), developed by the labs of Profs. Jae-Byum Chang and Young-Gyu Yoon (former SynthNeuro postdocs running labs at KAIST), could empower studies of how multiple systems (nervous, immune, etc.) interact across scales.
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Jörg Enderlein
9 months ago
I'm thrilled to share that our review article, "Molecular Level Super-Resolution Fluorescence Imaging," has now been published online (
www.annualreviews.org/content/jour...
)! We provide a comprehensive overview of fluorescence super-res methods that push the limits towards molecular-scale imaging.
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Molecular Level Super-Resolution Fluorescence Imaging | Annual Reviews
Over the last 30 years, fluorescence microscopy, renowned for its sensitivity and specificity, has undergone a revolution in resolving ever-smaller details. This advancement began with stimulated emis...
https://www.annualreviews.org/content/journals/10.1146/annurev-biophys-071524-105321
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Luciano A. Masullo
9 months ago
ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬 The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now.
#glycotime
#microscopy
www.biorxiv.org/content/10.1...
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Boston Bacterial Meeting
9 months ago
SAVE THE DATE ‼️ 📆 📢 BBM 2025 will be held on June 9-10th at the Harvard Science Center feat. the one and only Dr. Petra Levin as keynote! We can't wait to see you there. Registration and scholarship applications open next week.
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Evelina Tutucci
10 months ago
Awesome data from the Moffit lab!
#spatialbiology
www.science.org/doi/abs/10.1...
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Highly multiplexed spatial transcriptomics in bacteria
Single-cell decisions made in complex environments underlie many bacterial phenomena. Image-based transcriptomics approaches offer an avenue to study such behaviors, yet these approaches have been hin...
https://www.science.org/doi/abs/10.1126/science.adr0932?af=R
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STCmicrobeblog
10 months ago
STC is back
schaechter.asmblog.org/schaechter/2...
#MicroSky
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Is there a future for STC?
by Roberto – The short answer to that question is an enthusiastic YES! Of course, there is a future for STC, and I think it is bright. The long answer, well... that's what this post is all about It r...
https://schaechter.asmblog.org/schaechter/2025/01/is-there-a-future-for-stc.html
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Séamus Holden 🔬🦠🧫
10 months ago
Interested in a single molecule bacteriology PhD? Deadline 16th Jan. Location Warwick, UK Broad topic is the physical biology of the bacterial cell wall. Could suit almost any scientific background, eg biology, physics, biochemistry, chemistry, computer science.
www.findaphd.com/phds/project...
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Single molecule biology of bacterial cell wall remodelling at University of Warwick on FindAPhD.com
PhD Project - Single molecule biology of bacterial cell wall remodelling at University of Warwick, listed on FindAPhD.com
https://www.findaphd.com/phds/project/single-molecule-biology-of-bacterial-cell-wall-remodelling/?p179557
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Tom Ellis
10 months ago
Exciting new
#synbio
engineered living materials work from Chao Zhong, Peng Huang and Bolin An's team in Shenzhen has just come out on bioRxiv. Lovely demonstration of how engineered E.coli can sense and treat in vivo.
www.biorxiv.org/content/10.1...
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Ákos T Kovács
10 months ago
Bacteria use exogenous peptidoglycan as a danger signal to trigger biofilm formation
#Vibriocholerae
@naturemicrobiol.bsky.social
from
@knutdrescher.bsky.social
www.nature.com/articles/s41...
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Bacteria use exogenous peptidoglycan as a danger signal to trigger biofilm formation - Nature Microbiology
Peptidoglycan released by neighbouring kin or non-kin cell lysis induces physiological changes that protect from a range of stresses, including phage predation.
https://www.nature.com/articles/s41564-024-01886-5
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Jan-Willem Veening
12 months ago
I had some help 🎶 Teamwork makes the dream work! Checkout our latest preprint spearheaded by Jessica Burnier in a great collaboration with the labs of Waldemar Vollmer,
@nizet.bsky.social
& Malcolm Winkler
#MicroSky
www.biorxiv.org/content/10.1...
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A bacterial cell wall repair and modification system to resist host antibacterial factors
Pathogenic bacteria have acquired the ability to resist antibacterial defense mechanisms of the host. Streptococci are common in animal microbiota and include opportunistic pathogens like Group A Stre...
https://www.biorxiv.org/content/10.1101/2024.11.08.622053v1
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Saloni
11 months ago
Many people talk about the "Golden Age of Antibiotics", but I hadn't seen it visualized properly. Just how many types of antibiotics were discovered during that time? So, I visualized it myself!
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HARIBO bacter for happy holidays
11 months ago
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add a skeleton here at some point
11 months ago
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Mark A. Hanson
11 months ago
PLOS to move away from APC model. PLOS moves designed to make publishing equitable.
plos.org/redefining-p...
#ScientificPublishing
#AcademicSky
#AcademicChatter
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Redefining Publishing: PLOS, supported by the Gordon and Betty Moore Foundation & Robert Wood Johnson Foundation, is launching an important new initiative
PLOS believes in a better future where science is open to all, for all. We are redefining publishing by demonstrating that new solutions are feasible and deliver tangible benefits for the entire resea...
https://plos.org/redefining-publishing/
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Drew Bridges
12 months ago
Excited to share our latest, "Biofilm dispersal patterns revealed using far-red fluorogenic probes."
@plos.bsky.social
We developed a cell-labeling strategy using far-red dyes to image dense microbial communities (where fluorescent proteins often do not work well)
journals.plos.org/plosbiology/...
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