Sorry but I believe in society

re-upping this in light of the very amusing Granta fiasco

Billionaires must be targeted with tax policy and antitrust policy not because it helps everyone else (though it does) but because their political power must be limited so they can't wreck the world the way they're currently doing

Insane

The vice president of the United States is just standing up here saying people should feel sorry for domestic terrorists who were given free and fair trials and were then convicted in a court of law. Absolutely despicable.

Important: Dems will seek to force Republicans to vote on a bill blocking Trump's illegal $1.8 billion slush fund, Rep Jamie Raskin tells me. Dems will use discharge petition. Hakeem Jeffries is supportive of Raskin's efforts, I'm told. New piece from me: newrepublic.com/article/2106...

This article is essentially a confession that legacy media has so internalized the different benchmarks via which they judge Republicans and Democrats, they're comfortable expressly writing articles on that basis.

The “we don’t have the votes” excuse for refusing to force a vote on impeachment is conceding the point and saying even the opposition party doesn’t think this high crime merits removal from office. It’s not being politically astute and pragmatic, it’s self-defeating in its cowardice.

MIT is doing less research and enrolling fewer graduate students as a result of federal actions, the university president warned. Federally funded research on campus is down more than 20 percent compared to this time last year, she said.

More on the destruction of US science: Federal science agencies lost more jobs in 2025 (12%) than over the previous TWO decades (8%), including 30% of personnel at NSF, 20% at USGS, NOAA, and NIH. NASA lost 12% (now up to 24% by Jan 2026). (Data from www.aip.org/fyi/federal-...)

If you’re having AI do your brainstorming, “your brainstorming muscles are going to get weaker,” the MS NOW host Chris Hayes tells @cwarzel.bsky.social. They discuss the possible effects of letting AI take over creative and generative thinking: www.youtube.com/watch?v=da8U...

We are implementing a similar policy at @arxiv.bsky.social. If there is incontrovertible evidence of LLM slop in a paper, this means the authors did not take the time to read the LLM output and we can't trust anything else in the paper. Penalty is 1 year ban from arXiv followed by...

Why can't we explain enhancer action despite 2 decades of chromosome conformation technologies? 😬 Our new study spearheaded by Leonid Mirny's group points to a flaw in our assumptions, and to a solution from physical principles By @timothyfoldes.bsky.social 💻& @karissalhansen.bsky.social 🧪 🧵👇

We invented “triplet tumbling microscopy” (TTM) to track protein-protein interactions in living cells! Tag your protein with GFP and see it interact with *untagged* binding partners www.biorxiv.org/content/10.6...

its true that i dont understand how the supreme court operates. for example do you get the free RV and house for your mom before or after issuing favorable rulings? is it a *wink wink* deal or more explicit? these are the things the general public doesnt understand

incredibly funny how the outbreak happened after the two main countries involved, the united states and argentina, completely obliterated their public health and regulatory agencies for insane kulturkampf reasons

New preprint out!🧬 How do cells keep replicated sister chromatids linked for DNA repair while folding 3D loops for gene expression? Extrusion folds DNA but separates sisters, while cohesion connects them, risking mutual interference. How do they coexist?🧵👇 🔗 doi.org/10.64898/2026.05.02.722390 1/6

Excited to share our first story led by @martinacapriati.bsky.social! How do cells control the expression of viability genes? We find that single transcription factors can drive both chromatin opening and gene activation from densely co-bound CpG island promoters, including at essential genes

The voice of a deeply corrupt man running a deeply corrupt Court.

🚨Our preprint on DL for single-image super-resolution in microscopy is out!🌟 sl1nk.com/p62yedg Our benchmark recaps an adventure of learning and questioning with @ivanhcenalmor.bsky.social & @iarganda.eurosky.social 🌟 how to objectively assess SISR models & ease the choice for their use in👉 biology🔬

very funny that ilya shapiro walks around like he is some grand arbiter of merit when he would be unemployable if not for wingnut welfare

Q: How do you feel about this administration’s emphasis on fossil fuels and tariffs? A: The leaders of industry know that we need to decarbonize our economy... ... Unfortunately, the Trump administration has been moving in the other direction."

www.nature.com/articles/s41... An insighful study, leveraging MINFLUX to study chromatin dynamics by the @andersshansen.bsky.social lab @natsmb.nature.com . I am left wondering what if how we model chromatin with polymer simualtions needs rethinking, but surely many interesting findings here.

i bet this goes crazy if you’re a dumbass

hi everybody, asmita here back at it again with another preprint for your attention. excited to share our new fluorogenic speed probes that enable whole cell 3D imaging! 🔬

(1/n) Thread @matteomazzocca.bsky.social @domenicnarducci.bsky.social Simon Grosse-Holz @jessematthias.bsky.social preprint Q: how does chromatin move? Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide answers www.biorxiv.org/content/10.1...

Very excited to have been a part of this great work with @matteomazzocca.bsky.social, Simon Grosse-Holz, @jessematthias.bsky.social, and @andersshansen.bsky.social. Please check it out now! www.biorxiv.org/content/10.1...

So I've gotten some secondary confirmation of this, sorta, though it's possible it's—this will shock you, surely—a bit chaotic in its implementation. I'm also hearing that at least in some sub-institutes, phones and laptops are having location services turned on remotely where before they were off.

I am a biologist. This policy is based on disinformation and is also extremely harmful to many of our community members. Here is your biological truth: there is no single and universal set of criteria that delineates or defines "distinct" sexes. We are a beautifully variable species!

A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms.

🔬peeps! I am delighted to finally publish my code for controlling a spatial light modulator (SLM) to perform adaptive optics & to sculpt the vortex beams for STED & MINFLUX microscopy - complete w graphical user interface for easy use! github.com/wiebkejahr/s... Short user manual🧵

Brief thread on our opinion article "Q-rich activation domains: flexible ‘rulers’ for transcription start site selection?". Transcription people are surely aware of the important reports on the DNA sequence determinants of start site (TSS) selection in the human genome that came out this year. 1/15

Please check out our new paper showing that the supposed looping factor ZNF143 has no role in chromatin looping: www.cell.com/molecular-ce... And also check out the companion paper from @andersshansen.bsky.social: www.cell.com/molecular-ce...

Excited to share @domenicnarducci.bsky.social 's paper now out in Mol Cell published back-to-back with the paper from @dewitlab.bsky.social‬ - despite lots of prior work, we find that ZNF143 has no looping function www.sciencedirect.com/science/arti... www.sciencedirect.com/science/arti...

www.biorxiv.org/content/10.1... Our study published today on #bioRxiv describe the identification of a deaminase that converts 5mC to T, enabling direct sequencing of the human methylome and genome. This achievement was made possible through a collaborative effort across all departments at #NEB.

How did we get here, with a prominent anti-vaxxer nominated to lead Health and Human Services, with its $1.7T budget? Much of it can be traced to this retracted 1998 paper, falsely linking the measles, mumps and rubella (MMR) vaccine to autism. 1/3