Excited to share our new study using metagenomes to reveal key players in 2,6-Diaminopurine (dZ) Biosynthesis : We explore how some bacteriophages swap dA for 2-aminoadenine (dZ) in their genomes to evade bacterial defenses. #PhageBiology #Metagenomics #bacteriophage www.biorxiv.org/content/10.1...

So happy to share our new study “A Bait-and-Switch strategy links phenotypes to genes coding for Polymer-Degrading Enzymes in Intact Microbiomes.” In this work, we discovered novel chitinases directly on microbiome; a study brilliantly led by Dr. Colleen Yancey www.biorxiv.org/content/10.1...

🧪⚒️Just released an episode on the dynamics of subduction zones with Claudio Faccenna. Not only do trenches roll back and move laterally, they also advance and flip polarity. But when they penetrate the viscous lower mantle they get locked in place. Enjoy listening!

A novel NGS-compatible Enzymatic Strategy Enables Carryover Contamination Removal and Enhances Sequencing Performance. https://www.biorxiv.org/content/10.1101/2025.08.01.668201v1

Dream of avoiding carryover contamination in your NGS experiment? Check out our latest preprint: 🧬 “A Novel NGS-Compatible Enzymatic Strategy Enables Carryover Contamination Removal and Enhances Sequencing Performance” www.biorxiv.org/content/10.1...

This is wild! Engineering E. coli bacteria to turn plastic waste into paracetamol (Tylenol) www.nature.com/articles/s41... www.nature.com/articles/s41...

🧬🧫🦠 @science.org Bacterial reverse transcriptase synthesizes long poly-A–rich cDNA for antiphage defense | Science www.science.org/doi/10.1126/... #microbiology #bacteriophage #antiphage #immunity #DNA #RNAsky #RT #Cryo-EM #DRT9

The BASEL collection of E. coli #phages is limited by its host strain. @humollidorentina.bsky.social @damienpiel.bsky.social @aharms485.bsky.social &co use a modified host to add 36 new phages, revealing roles of O-antigen in recognition & R-M systems in immunity @plosbiology.org 🧪 plos.io/4jirGvX

Proxi-RIMS-seq now enables direct study of epigenetic modifications in microbiomes using Illumina sequencing on genome-resolved microbiomes ! Learn more in our latest work with @phasegenomics: doi.org/10.1093/nar/...

#StandUpForScience #Toulouse @sufs-paris-rp.bsky.social @emmanuelleperez.bsky.social "C'est très important d'avoir un lien très fort entre la recherche et la formation, de former à l'esprit scientifique pour se confronter à la complexité du monde d'aujourd'hui" www.francetvinfo.fr/replay-jt/fr...

Hair ice!! This is caused by a fungus in the wood. I'm always excited to find it when it gets cold.

Genomes assembled from #metagenomes (a.k.a. MAGs) are awesome and have revolutionized our ability to study uncultivated microbes ...BUT: they still don't capture a lot of the 🦠 species that are out there New @jgi.doe.gov paper led by Dongying Wu and Natalia Ivanova: www.science.org/doi/10.1126/...

How can single-cell transcriptomics profile phage infection in individual microbial cells? Check out our preprint with Anika Gupta, Norma Morella, Dmitry Sutormin & other authors, in collaboration with Georg Seelig (UW) and Neel Dey (Fred Hutch). www.biorxiv.org/content/10.1...

Our paper on 🦠queuosine 34 modification of tRNA tyrosine and antibiotic response is finally out in its final form in @eLife ... and quite different from the preprint version. Many thanks to reviewers, editors and kudos to all authors🙏 elifesciences.org/articles/96317

What is the diversity of antiphage systems out there ? We used protein and genomic language models (and defense score!) to start bringing some answers: >45 000 protein families. Leb by E. Mordret. www.biorxiv.org/content/10.1... Interactive UMAP to have fun mdmparis.github.io/antiphage-la...

Methyl-CODEC enables simultaneous methylation and duplex sequencing https://www.biorxiv.org/content/10.1101/2024.12.23.630102v1

Tracking bacterial ‘seeds’ in new soil reveals how they grow, adapt, and pave the way for next-gen microbiome therapies. @gangfang.bsky.social @biorxivpreprint.bsky.social t.co/QisGjqmInv #ImmunoSky 🧪

Transposable element exonization generates a reservoir of evolving and functional protein isoforms: Cell www.cell.com/cell/fulltex...

Stunning free #science vector art for your next poster, paper or talk 🤩 The #NIH has compiled over 2,000 illustrations including swatches and pattern brushes bioart.niaid.nih.gov #rstats #dataviz #phd #illustration

Glad to share our preprint 🏃 **LongTrack**: long read metagenomics-based precise tracking of bacterial strains (and their genomic changes!) after 💩 fecal microbiota transplantation. A 4+ years journey and tour de force by ** @yufan01.bsky.social ** & team. A long 🧵 www.biorxiv.org/content/10.1...

www.biorxiv.org/content/10.1... Our study published today on #bioRxiv describe the identification of a deaminase that converts 5mC to T, enabling direct sequencing of the human methylome and genome. This achievement was made possible through a collaborative effort across all departments at #NEB.

Happy to have found a home again at #bluesky 🙂