See our recent review on proximity chemistry to study RNA biology. If you are interested in getting into the field, this is an easy way to get caught up on the chemistry and technology: www.sciencedirect.com/science/arti...

Last preprint from @vicidominilab.bsky.social with @murat-sunbul.bsky.social! First live-cell diffusivity analysis of lncRNA NEAT1-1, using 🧬biRhoBAST and 🔬FFS. Beyond paraspeckles and microspeckles, we resolve distinct nanoscale complexes in the nucleoplasm. www.biorxiv.org/content/10.6...

New #preprint 😍‼️ led by 2 incredible postdocs @ninizhani.bsky.social & Ranj Papareddy: transforming #UFMylation from a local ribosome rescue pathway to systems level regulator of mRNA splicing www.biorxiv.org/content/10.6... A short 🧵

Excited to share my first PhD student’s @biorxivpreprint.bsky.social! Tracking 5 dyes simultaneously Kavan Gor @embl.org tracks nascent #RNA folding during #ribosome assembly to correlate structural with functional information on single RNA molecules! Check it out! www.biorxiv.org/content/10.1...

Congratulations again, Xiao-Xiao! It is a pleasure to host you as a Humboldt Research Fellow @humboldt-foundation.de. Looking forward to the exciting science ahead!

A new Review by Agnese Nicoli and Michelle Frei examines the progress in developing synthetic small-molecule fluorophores and how these in combination with innovative labeling strategies can advance chemical biology www.nature.com/articles/s41...

A new paper from @aliceyting.bsky.social reports on LaccID, an engineered laccase, that enables hydrogen peroxide-free proximity labeling and electron microscopy of cell surfaces www.nature.com/articles/s41...

Finally out! I’m thrilled to share our new paper (Wolin et al., Cell 2025). This paper describes SPIDR, a high-throughput method for mapping RBP binding sites. By combining #SPIDR with #cryoEM, we identified the exact binding site of LARP1 within the #mRNA channel of the 40S ribosomal subunit.

Teaching an old bacterial protein new tricks: Fast, bright and reversible rhodamine tags for live-cell imaging: www.biorxiv.org/content/10.1... Congratulations to Julian Kompa and the entire team.

Hello! Ever wonder what's "talking to" your favorite transcript, but were too scared to ask? In our review in @cp-cellreports.bsky.social, @mardakheh.bsky.social and I highlight new RNA-focused tools for discovering RNA interactions across organizational scales. Checkit! tinyurl.com/ydn6e3ac

Read the News & Views highlighting this work, here! www.nature.com/articles/s41...

Neat paper in JACS. They use a modified version of RhoBAST to do super-res imaging of demethylation of m6A by FTO pubs.acs.org/doi/10.1021/...

Happy to see my Postdoc work out @natbiotech.nature.com. Using HaloTag and synthetic fluorophores instead of FPs enables us to shift the spectral properties of kinase activity reporters (KARs) to the far-red 🔬. Huge thanks to everyone involved @jinzhanglab.bsky.social! www.nature.com/articles/s41...

Single-molecule live-cell RNA imaging with CRISPR–Csm - @doudna-lab.bsky.social @qb3-berkeley.bsky.social @innovativegenomics.bsky.social go.nature.com/3EJPKsM

Nature research paper: De novo design of transmembrane fluorescence-activating proteins https://go.nature.com/4k2OAZA