Today we’re delighted to launch Sequence ME & Long Covid - the world’s largest long-read, whole-genome study of any disease 🔬 🧬 This £20 million ground breaking initiative will explore the root causes of ME and Long Covid, with the aim of accelerating progress towards diagnostics and treatments.

look at my country man, we’re getting out-No Kings’d by the fuckin’ british

The media management of this Andrew news… pre-shadowed by an unusually frank interview with the head of the CPS in the Sunday Times hinting there might be action… then BBC getting the story…

Thrilled to share that my graduate work is officially published in Neuron! 🎉 www.cell.com/neuron/fullt...

Normalize laughing derisively in men's faces when they deserve it.

Yes,,, your boy has taken a ride in the 4 man bobsled,,, but im an adrenaline junkie and needed to try skeleton. And now I’ve officially joined the team and am gonna try to start competing. 66 years old going 66 mph.

BBC's Arabic radio service in Lebanon closed after 85 years as part of a £28.5m savings drive. 'Just months later, in October 2023, the Russian state-owned Sputnik news agency took over the frequency. Its news bulletin opened with “This is Moscow”, replacing the previous “This is London” intro.' 🙄

Bluesky is the new science Twitter, new study by @whysharksmatter.bsky.social and Julia Wester concludes! "Results show that for every reported professional benefit that scientists once gained from Twitter, scientists can now gain that benefit more effectively on Bluesky than on Twitter."

Do subterranean mammals have hyper-elastic skin thanks to super-sized hyaluronan (HA) polymers? We challenge this popular idea in a new preprint, presenting the first skin elasticity measurements of burrowing rodents & HA size profiles for Ansell’s mole-rat (1/8) 🧪 www.biorxiv.org/content/10.6...

😂

Something compelled me to make this

This is the stranger’s case, And this your mountainish inhumanity

🔴 BREAKING: Labour Together paid controversial PR firm £30k to investigate journalists who were digging into how its undeclared funding Reporters from Sunday Times, Guardian and other outlets targetted *And* Morgan McSweeney knew about it Full story: democracyforsale.substack.com/p/exclusive-...

But, as they say, there is no time like the present [OK, maybe the 1930s if you want to nitpick] But, with some data wrangling, my first NSF Funding Curves! 2/3

Weird and almost universal revisionism today. Even at the time, it was pretty clear that Mandelson wasn't appointed *despite* his dodgy links but *because* of them. Trump's Washington is a dirty swamp. Mandelson was deemed a man able to swim in it. This wasn't a secret. Everybody said it out loud.

I was a White House ethics lawyer. I used to advise people not to even accept a free cup of coffee from someone who had interests before them. And staff followed those rules. I can’t even find the words to describe the scale of Trump’s corruption here.

'"We definitely screwed up" says King...she wishes she'd posted the study as a preprint so that the errors could have been caught sooner' www.nature.com/articles/d41...

"AI is rapidly populating medical records with synthetic content, creating a feedback loop [that] drives a rapid erosion of pathological variability and diagnostic reliability...this renders AI generated documentation clinically useless after just two generations" www.medrxiv.org/content/10.6...

It's rare to see how lobbyists operate. But the Epstein-Mandelson correspondence shows us what happens all the time: plutocrats and government ministers conspiring against the public interest. This is why all lobbying should be in the public domain, but despite Labour and Con promises, it's not. 🧵

A study using fruit flies as a model can explain aspects of neurodegenerative diseases that have baffled scientists for decades. @poppi62.bsky.social's research focuses on axons - which allow brains to control behaviour and movement. www.sciencedirect.com/science/arti...

Make your gene knockouts more efficient with multiplexed Cas12a sgRNAs. Our new paper is out now, with tools available from @addgene.bsky.social , www.plasmids.eu and @vdrc-flies.bsky.social. www.nature.com/articles/s41... #CRISPR #geneediting #Drosophila 🧪🧬✂️🔬🪰 Summary 🧵 below.

TDP43 filaments in synapses

Some initial reactions to the 'published on a Sunday afternoon' letter from the CEO of UKRI. 🧵 www.ukri.org/news/open-le...

and no I haven't put the Mandelson-Epstein-Reinaldo scoop on twitter we journalists *can* make Bluesky the place to break news

FoldMason is out now in @science.org. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and @milot.bsky.social. 📄 www.science.org/doi/10.1126/... 🌐 search.foldseek.com/foldmason 💾 github.com/steineggerla...

We could have 4 JWST’s or a science mission at every planet. The NIH could be funded for two years. Or 1.5 years or so of USAID funding, if it still existed. This is how they’re spending our tax dollars. This is our money.

Working on two paper rejections/major revisions whilst teaching and fighting for your job with only five months left on your contract is....draining... #academia 🧪

Now online! Peripheral cancer attenuates amyloid pathology in Alzheimer’s disease via cystatin-c activation of TREM2

What are we doing here Ed tech is profitable. It is also mostly useless economist.com/united-state... from The Economist

Absolutely cracking work here from Jim's team. I defend the BBC a lot, but when a small team is doing really solid work like this while BBC London is doing puff pieces about the Wicked films, it really does make you wonder what's gone wrong with the big news outlets.

This week, an X user created an AI video of me being chloroformed and prepared for rape. Victims are told it's not real and they're getting offended for no reason. But nudification tools are weapons of sexual assault, and the harm they cause is real 👇 jessasato.substack.com/p/ai-nudific...

www.joxleywrites.jmoxley.co.uk/p/airport-bo... Great piece on “airport book brain” - the tendency of politicians to swallow simplistic solutions. Latest example the Jonathan Haidt book shaping policy on teens and social media

I for one am extremely excited for the entire UK media to spend the next few months obsessing over a single constituency in the Westminster Parliament when general elections to Holyrood and the Senedd are rapidly approaching

This UK university finance dashboard is so good. Incredible public service.

Greens or Lib Dems should campaign on ditching all these contracts which are an abomination and a liability.

Clever new method for assembling DNA oligos into larger sequences without the need for unique overlap sequences. Can't wait for those 'this sequence is too complex' rejection messages from DNA suppliers to become a thing of the past. 🧬🧪 www.nature.com/articles/s41...

Very grim. www.ft.com/content/c894...

reading up on the Pitchfork subscription thing. apparently if you don't subscribe you can no longer read every review. and it sounds like their archive of reviews will not be open to non-subscribers anymore either.

Trick Bag, Aquarium Drunkard, Stereogum, Hearing Things, a billion independent newsletters…just saying! if you cherish the spot where you read about music, especially if it’s eternally dangling on the precipice of financial oblivion because there’s not a corporation behind it, throw them some money.

Deutsche Bank here with the good stuff. Game on.

Northern Lights over Greenland 🇬🇱

What Europe could do is threaten to boycott the World Cup. It won't. But that might actually work. Trump wants his big show.

pretty sure he meant the other thing, grok, but very cool that those are your two things

Delighted to see the vindication of Scotland's position here - not just ScotGov, the policy was approved by Parliament as a whole. It was deliberately wrecked by bully tactics of a right wing UK govt that was willing to sacrifice our environment, our economy and people's jobs, for petty politics.

Hats off to whoever did this (and the beautiful model).