Australian #NHMRC Ideas grants are out. 8.1% success rate. Lowest since the scheme began. Congrats to the successful few, as it looks like less than 200 were funded. 🧪

Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis www.cell.com/molecular-ce...

Measuring mitochondrial membrane potential @marcliesa.bsky.social , Guillermo Martínez-Corrales et al @ibmb-csic.bsky.social comment on common misinterpretation of mitochondrial membrane potential measurements & suggest guidelines for accurate determination in cells www.embopress.org/doi/full/10....

As a reviewer, please don't overuse AI to write your grants. I understand the need for a quick editing/grammar check, but the structure of the paragraphs and the logic is absolutely awful. I can spot it in a nanosecond.

Excited to share our study out in @natcellbio.nature.com! Led by @mikelangelipid.bsky.social, we identify the first #LipidDroplet lipid quality control pathway: LD-localized FSP1 protects stored lipids from oxidative damage and prevents LD-initiated #ferroptosis. www.nature.com/articles/s41...

Excited to share my postdoc work @olzmannlab.bsky.social! We found lipid droplets, the cell’s lipid storage depots, are subject to oxidative damage and are protected by FSP1. Loss of FSP1 triggers droplet peroxidation and cell death, revealing a new layer of lipid quality control! shorturl.at/B5XYD

reactant and product metabolite ratios revealed metabolic pathways differences between cancer subtypes and noncancer cell lines by @hoylipidlab.bsky.social @sydneyprecisionds.bsky.social @nancyts.bsky.social ➡️ www.embopress.org/doi/full/10....

This is such an incredible paper. Must read if you care about metabolites and cores organ interactions. For me most interesting finding is that the liver is NOT the only organ that converts cholesterol to bile acids. But ther are so many cool onserbwtions www.cell.com/cell/abstrac...

Can we use what we’ve learned so far about #immunometabolism in macrophages and neutrophils as cancer immunotherapy? Not yet, but someday. I’m happy to share our latest review, summarizing the state of the field in the context of #myeloidcells and #lungcancer www.sciencedirect.com/science/arti...

Incredibly proud of our latest publication in @molsystbiol.org led by @nancyts.bsky.social in collab w/ Jean Yang and Lake-Ee Quek - www.embopress.org/doi/full/10.... We curated targeted metabolomic data into pathway-centric ratios and identified subclusters of cancer cells with distinct features.

Our group leader Prof Nigel Turner was interviewed for the Guardian earlier this week, discussing the hype and hope for NAD+ boosters as anti-ageing therapeutics. Read what he (and our collaborator A/Prof Lindsay Wu) had to say about it here: www.theguardian.com/australia-ne... 🧪

A Future Made in Australia … as long as no new knowledge is needed.

ARC has “paused” future rounds of grant schemes pending outcomes of its NCGP Policy Review. All schemes previously scheduled to open before 1 July this year will go ahead. But next year’s Laureates, Industry Fellowships & Discovery Indigenous won’t. See table👇 & www.arc.gov.au/funding-rese...

happy to share our forum now online @Cell_Metabolism! fun for us (Guy & myself) to collaborate with @dfazakerley.bsky.social, Joycelyn, & Sam in putting together what we hope will be a useful piece for the broad metabolism community re: in vitro modeling! www.cell.com/cell-metabol...

When I try to explain how things are actually getting worse, people look at me like I'm crazy.This piece is spot on. #SIStem (senior #womeninSTEM)

Join us in Austin, TXm Feb 9-10 2025, for an Abcam-sponsored symposium on Cancer and Metabolism. -RJD events.abcam.com/event/cancer...

a fitting first post to mark the beautiful PhD thesis defense this afternoon from our lab’s very first student! Kim’s courage to join a brand-new lab and her ensuing grit, enthusiasm, and creativity were exceptional! extremely proud of all she has achieved, stay tuned for some of her cool findings!

I'm thrilled to share our latest research, published in Nature Communications. This work highlights how pancreatic cancer cells hijack cell polarity proteins to regulate macropinocytosis and tumor metabolism, shedding light on potential therapeutic vulnerabilities. www.nature.com/articles/s41...

Registration is open for #METPHYS2025! www.sablesys.com/metphys2025-...

We are hiring! There is still time to apply for an open postdoc position in stem cell metabolomics (mass spec experience required) in our lab, and we’ll soon open applications for a PhD student interested in studying metabolic crosstalk in the bone marrow (but feel free to already send me your CV)!

So good - @voodooglowskulls.bsky.social and Hey Smith in Sydney!

We've seen this movie before, Minister @jasonclaremp.bsky.social, in Japan. Please help us take a different path!

We’ve had nearly 3 years of review, review, review. We need reviews, but it’s blindingly obvious that Australian research needs much greater Government investment while those reviews are done. This was true 3 years ago. Still true now. By @drjr.bsky.social

Only a subset of patients respond to immunotherapy Why? Which ones? We conducted an unbiased analysis of response biomarkers and found that hundreds of possible biomarkers collapse into five latent, orthogonal factors that underlie immunotherapy response. www.nature.com/articles/s41...

You can't save your university by cutting. That's an illusion. You can only weaken it further. See: the logic of Mr George Osborne, 2010-c.2013. Every redundancy programme in fact takes you closer to the edge. How can there still be people out there who don't realise this?

If your #NHMRC ideas grant was unsuccessful and you have a story to share about the impact of this on your #biomedicalresearch, career, team - get in touch. Federal DOH have asked #NARF to collect stories of impact of low funding. #SaveOzScience #DiscoveriesNeedDollars #EMCRs

Huge day in Australian Research with grant outcomes for both #ARC Discovery Projects and #NHMRC Ideas released. Congratulations to all those successful, and sincere apologies to the >85-90% who missed out. It's a brutal, brutal system with so many great grants and research missing out.

Join us in Boston! The Department of Molecular Metabolism (MET) at the Harvard T.H. Chan School of Public Health has just opened a Jr. Faculty search. Apply by January 15, 2025 at academicpositions.harvard.edu/postings/14371

I created a simple flow chart to help my lab trainees choose the most appropriate stats test in Prism (*for single-factor comparisons only). Feel free to share with your group if you think it could be helpful first start.

Interested in tissue immunity in infection, focusing on adipose tissue, brain and immunometabolism? Then come join me & @juanquintana.bsky.social at @lydiabeckeriii.bsky.social as a research assistant Email to arrange an informal chat 🧪 #ImmunoSky #LGBTQSTEM www.jobs.manchester.ac.uk/Job/JobDetai...

First post on here and it's one I always love to post - celebrating the final presentation of our amazing hons Natalie. She did a brilliant job and a great way to finish the year. Always rewarding.

Is basic science undervalued? David Glanzman (UCLA) talks about the decline of 'middle class' labs and that "there is no empirical evidence that the translational approach accomplishes this [cures] any better than the traditional one. Claims to the contrary at this point are mere propaganda."

If you want to work at the interface of #cancer #dormancy #immunity in beautiful #Lisbon reach out to me. We have positions fully funded by #LaCaixa Join our amazing blue sky at Champalimaud Foundation ☀️