Congratulations to Gina and her team on the hard work and great effort; happy to be included in such a cool story! #immunosky #immunometabolism

Only single cell sequencing of the all these post docs will reveal why

Still riding this high of seeing one of the greatest gigs of all time with some of the greatest people 💕 #oasis #murrayfield #feelingsupersonic #morningglory

Dear Europeans who like to suffer through the 30+ degree weather, unable to sleep:

Just out in Infection and Immunity! Our latest review explores how neutrophils balance antimicrobial defense with tissue protection during infection, with a focus on metabolic signaling and NETs. Read it here: journals.asm.org/doi/full/10.... #neutrophils #immunometabolism #NETosis #hostpathogen

A comparison of mouse vs human tumor microenvironments shows a major difference. Mouse TMEs have more macrophages, while human TMEs have more T cells. Chemokine expression patterns are also different. Learn more: www.biorxiv.org/content/10.1...

Can we use what we’ve learned so far about #immunometabolism in macrophages and neutrophils as cancer immunotherapy? Not yet, but someday. I’m happy to share our latest review, summarizing the state of the field in the context of #myeloidcells and #lungcancer www.sciencedirect.com/science/arti...

Mark your calendars for the next T Cell Europe Lecture, featuring Stefano Angiari sharing his latest #immunometabolism research, from @medunigraz.at June 3rd at 5pm CET 11am EST www.t-cells.eu

archive.ph/qvH9r A great interview with one of my favorite “famous” people, Sufjan Stevens, in celebration of the 10th anniversary of one of the greatest and most developed albums of all time #carrieandlowell

P-hacking Removing outliers, using alternative statistical methods and running extra experiments are some methods that could be used to change the P-value. Be careful not to fall in this trap! Stay sceptical! Null results are a normal part of science. www.nature.com/articles/d41...

🚀 Förderung für engagierte Forscher*innen! 💡🔬 Bei der Pioneering Minds Award Ceremony wurden die Forschungsförderungspreise "GESUNDHEIT3000" verliehen. Der Verein #MEFOgraz prämiert innovative Projekte zur Verbesserung von Vorsorge, Früherkennung, Diagnose oder Behandlung ➡ https://bit.ly/4i7H66d.#MEFOgraz

#FactCheckingDay promotes media literacy and the importance of reliable information in the fight against disinformation. ERC Scientific Council member @lukeanthonyoneill.bsky.social shares why acting to counter disinformation matters to him as a scientist. 👇 #FactsMatter

Excited to post for the first time to present our exciting new paper @Nature. The fruit of massive work by Tommaso Vicanolo, @alazozcan.bsky.social and Jackson Li, and our superb collaborators Laiguan and Stefan Uderhardt. True teamwork! Free link: rdcu.be/eeeA2 www.nature.com/articles/s41...

Reviewers! Your job is to improve the scientific quality and integrity of a paper and make suggestions to solidify conclusions, not to gatekeep and make authors jump through unnecessary hoops to reach some invisible bar you’ve set in order to stroke your ego! we’ve all got it tough, don’t make worse

My favorite part about living in Austria is that at random times I’ll get a letter saying “oops we owe you money!” from the electric company, employer, landlord, etc. My landlord randomly lowered my rent by €50/month and then sent me back the difference. Jarring as an American (in a good way)

Fascinating work from MALDI master Ramon Sun and collaborators on glycogen metabolism in NSCLC. A real tour de force and such beautiful images 😍 www.nature.com/articles/s42...

Combining bacterial end joining with programmable nucleases, we induced mtDNA deletions in human cells at varying heteroplasmy and examined their metabolic and cellular effects. Simple tool to apply across any cell type and engineer pathogenic mtDNA deletions. www.sciencedirect.com/science/arti...

I love you, @theonion.com

Cool new stuff from the O’Connell lab! www.sciencedirect.com/science/arti...

Now online in Cancer Discovery: High Glucose Contribution to the TCA Cycle Is a Feature of Aggressive Non–Small Cell Lung Cancer in Patients - by Ling Cai, Nia Hammond, Brandon Faubert, @rjdlab.bsky.social, and colleagues doi.org/10.1158/2159...

Your cells are dying. All the time geneticliteracyproject.org/2025/01/27/y...

Nature research paper: IL-27 elicits a cytotoxic CD8+ T cell program to enforce tumour control https://go.nature.com/4guUvnp

Massive work from Jess Spinelli's lab at UMASS demonstrating a SECOND electron carrier in the mammalian ETC: www.cell.com/cell/fulltex...

I'm delighted to share a new story from our lab published today at @cp-cellmetabolism.bsky.social! In it, we describe how cellular therapies for cancer can be metabolically and epigenetically enhanced by redirecting how glucose is utilized during in vitro expansion. 1/ www.cell.com/cell-metabol...

Really interesting paper 🧪 🤩 Immune evasion through mitochondrial transfer 😮 Ikeda et al find that #mitochondria from cancer cells can #transfer over to T cells - altering their #metabolism & reducing antitumour immunity www.nature.com/articles/s41... www.nature.com/articles/d41... @nature.com

Fresh off the press! 🥳 Congrats to @alessiazotta.bsky.social @lukeanthonyoneill.bsky.social and team for this awesome paper, about mitochondrial complex III driving IL-10 production by macrophages. Thanks for having me and my Austrian colleagues as a part of this! ☺️ www.science.org/doi/10.1126/...

Distinct myeloid-derived suppressor cell populations in human glioblastoma doi.org/10.1126/scie...

Congratulations to Gabriel Rinnerthaler in the Division of Oncology @medunigraz and team for this new publication—an important clinical trial on how to harness the immunogenic properties of certain chemotherapies with immunotherapy combo and reduce toxicity www.nature.com/articles/s43...

My two personalities

💀

Pro-inflammatory macrophage activation does not require inhibition of oxidative phosphorylation | EMBO reports www.embopress.org/doi/full/10....

We thank the reviewer for their useful suggestions, which have greatly improved the paper

Love seeing that miRNAs are getting their flowers again in 2024 www.science.org/doi/10.1126/...

Minor inconveniences that left-handers suffer from in the lab 🧪 🥼: • When the aspirator hose in the cell culture hood comes from the right side and you have to twist your wrist in an awkward way to hold the aspirator pipette and also try not to make the hose knock things over in the hood

New paper out in @ScienceMagazine! In 8 studies (multiple platforms, methods, time periods) we find: misinformation evokes more outrage than trustworthy news, when it does it's shared more + ppl are less likely to read before sharing. w/ @killianmcl1 @Klonick @mollycrockett 🧵👇

A new compelling study demonstrating that so-called “M2” macrophages, often simply classified by the surface marker CD206, are actually essential in orchestrating anti-tumor responses. This negates previous studies referring to CD206+ macs as only immunosuppressive. rupress.org/jem/article-...

The real secret to the "Mediterranean diet" is eating equal qualities of pasta and antipasto so that they annihilate one another

Remember what they took from us.

where my lab night owls at?! 🧪

I'm looking at these cabinet appointments and vowing to never have impostor syndrome again

Here’s my spreadsheet of starter packs (>80!) related to broadly ‘mechanistic biology’ plus some intriguing extras Complete with collective nouns I’ve been tracking these but now can’t keep up Hope it’s helpful 2/2 docs.google.com/spreadsheets...

A Tuesday pick-me-up: here’s Deacon the blind senior goodboy rocking a beanie for the colder winter days #dogsofbluesky #australiancattledog 🧪 #weratedogs #patagonia

Life of a scientist

Happy Friday Bluesky scientists! 🧪 Let’s kick off some conversations, starting with a loaded question: what is your favorite scientific paper of all time? (Maybe a seminal study or just one that is so simple and elegant that you love) #academicsky #immunosky #biomedsky

An updated starter pack for #metabolism and #mitochondrialbiology go.bsky.app/VavECSX

Our preview of the recent Cancer Cell paper on itaconate in the tumour microenvironment. 🧪 I hope you enjoy the summary and perspective. www.sciencedirect.com/science/arti...

An exciting new story from Stefano Angiari et al. that was a joint collaboration between MedUniGraz and Uni Verona, demonstrating a protective role of the metabolite pantethine in T cell pathogenicity during #MS. Congrats! #immunometabolism #neuro jneuroinflammation.biomedcentral.com/articles/10....

Interested in #Immunometabolism? Here's a small starter pack of some great people to follow here on Bluesky! If you'd like to be added, please let me know :) go.bsky.app/MvxkA4Q

Waves of new BlueSky arrivals in last few days! I’ve been tracking starter packs relevant to molecular/mechanistic/genetic/cellular…etc biology Hope it’s helpful but warning: now a v long thread! Probably the last time I can do this...

Hi BlueSky friends! Sad about the US election and the downfall of #scienceTwitter, but happy to see many old and new friends migrating over here. Let’s talk and share about #academic research! I’m an #immunology researcher with interest in #immunometabolism and #tumorimmunology. Nice to meet you!