I gave in! After students asking for it, I now made a simple figure design checklist. To help all scientists w/o graphic skills create clear, accessible, and truthful charts! -> Out in @nature Cell Biology: rdcu.be/erwl4 #DataVisualization #PhD #SciComm Thx for review @bethcimini.bsky.social + 2

Here are some of the best entries in NPR's 2024 College Podcast Challenge.

The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis: @cellpress.bsky.social www.cell.com/cell/fulltex...

Peripheral infection wires T cells in the brain www.nature.com/articles/s41...

I’m thrilled to share our work out now in Nature identifying CREM as a central intracellular checkpoin in #CARNK cells. 📄Link: nature.com/articles/s41... Our story👇🏼

On-demand microglia deliver the therapeutic payload in Alzheimer’s disease @cp-cellstemcell.bsky.social www.cell.com/cell-stem-ce...

🚀 Excited to release BoltzDesign1! ✨ Now with LogMD-based trajectory visualization. 🔗 Demo: rcsb.ai/ff9c2b1ee8 Feedback & collabs welcome! 🙌 🔗: GitHub: github.com/yehlincho/Bo... 🔗: Colab: colab.research.google.com/github/yehli... @sokrypton.org @martinpacesa.bsky.social

A study published in Genome Medicine provides a framework to support the integration of a single untargeted proteomics test into routine diagnostic practice for the diagnosis of mitochondrial and potentially other rare genetic disorders. bit.ly/4dKQ48e #Epigenetics #MedSky

In #Science #Immunology, researchers at @stanfordmedicine.bsky.social studied #IFNs in human #fetal #thymus development. They found type I & II IFNs play distinct but critical roles in cortical & medullary thymic #EpithelialCell differentiation!

These beautiful pins came in! 🙌🏾 they’re gifts for our MINDS post-bacc scholars who will be starting grad school in the fall ❤️🎉 • • Always love supporting women-owned, people-of-color-owned businesses ✨ but I especially love supporting my friends @christineliu.art 😍 twophotonart.com

I am pleased to share our recent publication, fruit of a wonderful collaboration with truly amazing colleagues @adrienneboire.bsky.social and @meningojan.bsky.social, whose work was a tour de force demonstrating that immunology in the brain is a different beast -> www.nature.com/articles/s41...

Today in @nature.com , we report a spatial single-cell atlas of human cortical development, revealing surprisingly early specification of human cortical layers and areas. We built an interactive browser to explore the spatial data: walshlab.org/research/cor... Paper link below 👇

JCI - The gut microbiome controls reactive astrocytosis during Aβ amyloidosis via propionate-mediated regulation of IL-17 www.jci.org/articles/vie...

Online now: Pre-existing epigenetic state and differential NF-κB activation shape type 2 immune cell responses

#GliaPapers #GliaMay2025 MAY COVER Carl Weigert, Mihály (von) Lenhossék, Gustav Retzius, and Hans Held surround hand drawn images of glia from the late 1800 and early 1900s. (see Kettenmann et al, onlinelibrary.wiley.com/doi/10.1002/...)

T cell-specific antigens are discovered at high throughput without killing target cells go.nature.com/3L6cuDp rdcu.be/ekKtU

Our perspective in @natrevimmunol.nature.com on new concepts in neuroimmune interactions that have challenged the old dogma that immune privilege is a result of the isolation of the nervous and immune systems. @jonykipnis.bsky.social www.nature.com/articles/s41...

My mom used to love #FluorescenceFriday, so I will keep posting in her memory ❤️ This photo shows neurons in the hippocampus accumulating phospho-tau in our monkey model of Alzheimer's Disease. Markers: Dapi 🔵, Neun 🔴, pTau 422🟣, AT8🟡

Together with leading science organizations, ASM filed an amicus brief calling for immediate restoration of NIH grants supporting early-career scientists. Read the press release: asm.org/press-releas...

I’m excited to be speaking at #IMMUNOLOGY2025™ on May 7 during the Lymphatic Immunophysiology Major Symposium! Join us to discuss the meningeal lymphatic system and its impact on brain immunity and function. #immunology #neuroimmunology Register today! immunology2025.aai.org/register/ #AAI2025

Excited to share our new work demonstrating a role for astrocytic inflammasome signaling in modulating hippocampal plasticity. @cp-immunity.bsky.social All credit to Kristine Zengeler, who was the brains🧠 and muscle💪 behind this project and is a wonderful collaborator. www.cell.com/immunity/ful...

It was so great for my lab to be able to contribute to this awesome study led by @fchrisbennett.bsky.social @nachoriko.bsky.social @waisenberg.bsky.social.

Check out this paper from the Movahedi lab! It’s a great companion to ours - showing the populations of brain macrophages that monocytes can replace. Congrats to first author Jonathan Bastos!

Open call for Next Generation Leaders! Our NGL program recognizes early career scientists with fresh and innovative perspectives. For 3 years, NGLs contribute to ongoing research and initiatives at the Allen Institute. Apply by June 3. alleninstitute.org/about/people...

New NYT Article on the first 100 days in Charts www.nytimes.com/interactive/... Deeply concerning in many regards... Sadly (although it is good for folks to understand), NIH funding slowdown made the cut... 1/2

Mammalian cells eliminate nascent chains stalled during co-translational protein translocation by activating a ribosome UFMylation-dependent TAQC process at the ER. Ennis, Wang, Ye et al. establish a role for NEMF-mediated CAT tailing in TAQC. rupress.org/jcb/article/... #ER_literature

Our latest work now online in Cell: Rewriting regulatory DNA to dissect and reprogram gene expression Our new method (Variant-EFFECTS) uses high-throughput prime editing + flow sorting + sequencing to precisely measure effects of noncoding variants on gene expression Thread 👇

Native mass spectrometry enables real time characterization of MAPK phosphorylation cascade and impact of oncogenic RAS mutants on kinetics. doi.org/10.1038/s420...

At Princeton University we are being clear about our continued commitment to diversity and nondiscrimination, in full compliance with law (as opposed to executive order) and consistent with our ethical responsibilities as educators for the entire nation. www.dailyprincetonian.com/article/2025...

Explore top neuroscience meetings and events. Filter events by topic, and see upcoming webinars compiled by @worldwideneuro.bsky.social. Are you organizing a neuroscience conference? Share it with us at [email protected] #neuroskyence www.thetransmitter.org/events/?utm_...

An old favorite of mine - this retinal astrocyte (GFAP) looks like it’s dancing among blood vessels. #science #glia #microscopy

People want institutions to stand up www.thecrimson.com/article/2025...

For news, perspectives and more to help you navigate the early stages of your neuroscience career, visit our Early-Career Resource Center: www.thetransmitter.org/early-career...

Important new information about the Parent F32 (and likely other) funding announcements. 1/n

Dashboard updates jeremymberg.github.io/jeremyberg.g... 1/n

Disheartened to learn this. Dr. Ben Barres was a trailblazing neurobiologist that revolutionized the glia field & served as an advocate for many. Their scientific legacy will continue to be cherished & remembered.

The #HandsOff rally in Chicago is packed!

I’m just sayin’. St Augustine FL is a town of 14,000. In a red county. And we’re doing this. #handsoff #50501 #April5 AND we have some spicy signs!

#handsoff Birmingham, Alabama

Oh wow: Portland Oregon is NOT KIDDING #handsoff

Spectacular view of 100,000 people attending the #HandsOff march in NYC

💙 DC never disappoints. #handsoff

100,000+ people marched at the #HandsOff rally in New York!

#WeekendRead! #NotOnlyInterferons! @nanyanlab.bsky.social &co show @cp-molecularcell.bsky.social that other than inducing pathogenic IFNs in lysosomal storage disorders, STING also play protective functions as a proton channel activating TFEB & inducing lysosomal repair www.cell.com/molecular-ce...

HEY DORKS, GET YOUR SIGNS READY! *Two* upcoming opportunities to Stand Up for Science, together. 🚨TOMORROW APRIL 5TH🚨 In partnership with @indivisible.org we say: HANDS OFF OUR SCIENCE Find an event near you and register here: handsoff2025.com?utm_source=s... #standupforscience #handsoff

AlphaFold’s highly accurate structural models transformed protein biology. Nature reports on the efforts to create a similar system for RNA and why it’s a tougher nut to crack. #RNAsky 🧪

An important point getting overlooked: When NIH cancels "diversity" grants (e.g., diversity supplements, Fs, Ks, etc), they aren't canceling the grants based on *what* the grant studies. They're cancelling them based on *who* is doing the research. And that disallowed "who" is anyone not white.

“When a grant is awarded to a university, there are terms and conditions that go with the grant. It’s basically a legal contract…I don’t think it’s a foregone conclusion that the great majority of the terminations that have been done are in fact legal.” @jeremymberg.bsky.social