Honored to moderate a panel on noninvasive mapping of human brain circuits at MGB Neuroscience Day. Great insights from @anastasiayendiki.bsky.social @mghmartinos.bsky.social, @fredschaper.bsky.social @braincircuits.bsky.social, Alex Golby and Pravan Nanda @mgbneurosurgres.bsky.social.

Honored to highlight our work @braincircuits.bsky.social @massgenbrigham.bsky.social Neuro Research Day. Thank you @shansiddiqi.bsky.social @fredschaper.bsky.social Sheena Baratano and Sam Snider for sharing your experience.

Massive, Herculanean work by @laurenahart.bsky.social and Garance Meyer to compile and integrate findings from DBS for epilepsy (20 targets!) including meta-analytical evidence for optimal stimulation sites for the two main targets (ANT & CM). Preprint out now 👇👇

🧠 ⚡️ Preprint alert ⚡️ 🧠 I️n the most comprehensive review of DBS in epilepsy, with 124 studies, 1,210 patients, and 20 anatomical targets we map where stimulation works best and why. Deep Brain Stimulation for Epilepsy: Optimal Targeting and Clinical Outcomes www.researchgate.net/publication/...

Very hard to say goodbye to these fantastic people. I will miss you guys! @braincircuits.bsky.social!

🚨 🥁 Preprint alert: The Deep Brain Stimulation Response Network in Parkinson’s Disease Operates in the High Beta Band ->> www.researchgate.net/publication/... <<--

How does early life adversity impact white matter brain connections and subsequent cognitive abilities? Adversity was associated with lower white matter integrity and later difficulty with arithmetic & receptive language yet interpersonal resilience was protective. www.pnas.org/doi/epub/10....

Was fun to do a podcast about our recent paper on creativity and brain disease with Dr Norman Swan @abcnewsbot.bsky.social @braincircuits.bsky.social @foxmdphd.bsky.social @harvardmed.bsky.social www.abc.net.au/listen/progr...

Epic thread!🧵 #Neurology #NeuroSky #Epilepsy #Neuroscience

An amazing read and what a concise thread !!

This is amazing work!

Lesions causing epilepsy map to a brain circuit, but what about generalized epilepsy? Great new paper (and thread) by @fredschaper.bsky.social identifies this circuit with implications for #DBS. @braincircuits.bsky.social

New @braincircuits.bsky.social paper out at @naturecomms.bsky.social 👇👇

Fantastic new work by @fredschaper.bsky.social on mapping epilepsy onto brain networks! Congratulations Fred & team!

Is generalized epilepsy a seizure of the whole brain or a specific brain network? In our new paper out now in @naturecomms.bsky.social, we investigate this by combining brain abnormalities and DBS with the human connectome. Paper: nature.com/articles/s41... A 🧵 below:

Interested in an update on connectomic and adaptive deep brain stimulation for obsessive compulsive disorder? Take a look at our summary of this exciting field and how things could be brought together out now in BPS: www.biologicalpsychiatryjournal.com/article/S000... A brief 🧵

Out now in Brain A distinct pattern of brain damage intensifies political involvement, regardless of whether you're liberal, conservative, Democrat, or Republican. With coauthors S.Balters,S. Cohen-Zimerman,G.Zamboni,J.Grafman academic.oup.com/brain/advanc... @braincircuits.bsky.social

Can brain damage change your political opinions? “No significant neuroanatomical circuit was associated with political ideology or party affiliation, but a distinct circuit was associated with intensity of political involvement” Work by @shansiddiqi.bsky.social @braincircuits.bsky.social

Boston strong 💪 #marchforscience

Ever wondered how well your Lead-DBS electrode localizations compare to expert solutions on the same data? Now, with Lead-Tutor, you can self-assess!

A study in Nature Medicine provides a comprehensive map of the contributions of environment and genetics to mortality and incidence of common age-related diseases, suggesting that the exposome shapes distinct patterns of disease and mortality risk. #Medsky 🧪

The 12th Annual Deep Brain Stimulation Think Tank Proceedings are out and free to download. Check out Nico Dosenbach as he brings us up to speed on changes in the way we are thinking about the somato-cognitive action network (SCAN) functional connectivity to subcortex.

@andreashorn.org giving his Early Career Researcher Award Plenary lecture showing his imaging pipeline connectomics.

Super deserving of his award, @andreashorn.org identified specific tracts for specific diseases and even specific symptoms -> patient improvements in mx independent cohorts.

Amazing first talk by @barbarahollunder.bsky.social on OCD circuit subsymptoms as modulated by DBS at #brainstimconf

I am hiring: PhD students, postdocs, admin personnel. Email me if you know somebody that may be interested in joining us in Cologne! 👇👇 Please RT for reach! 🙏🙏

It’s a no brainer to join THE BEST brainer! 🧠@andreashorn.org is hiring, don’t wait to apply! Great opportunity to work with one of the best mentors and people in the field ☺️

I am excited to announce that I will be founding an institute for network stimulation at the University Hospital Cologne – already this coming May!

"fMRI does not measure neural activity". Correct, but...

Do we need to stimulate different circuits to improve different dystonia symptoms with STN DBS? Work by Konstantin Butenko, @andreashorn.org @braincircuits.bsky.social out today in @PNAS says yes: Engaging dystonia networks with subthalamic stimulation | PNAS www.pnas.org/doi/10.1073/...

🚨Interested in Dystonia?🚨 @braincircuits.bsky.social GPi DBS for dystonia is effective. More recently, STN DBS has been investigated, as an alternative. In what enfolded like a stunning thriller to me, Konstantin Butenko tells a tale of two networks… www.pnas.org/doi/10.1073/...

The brain’s action-mode is created by a dedicated action-mode network (AMN) rdcu.be/d5odm. In the brain’s mode continuum, AMN sits opposite DMN’s default-mode, as yin-yang. AMN might be key in pain, apathy, Parkinson’s. New @natrevneurosci.bsky.social w/ Marc Raichle & @gordonneuro.bsky.social 🧵 ⬇️

I keep updating the DBS starter pack – and super happy we have already 109 folks on here! Am I missing somebody? go.bsky.app/B9A9Cho

If circuits are in danger - we’re always here for the rescue!

Today we say goodbye to @bahnebahners.bsky.social who spent the last year with us as a Thiemann visiting fellow – safe travels, don't be a stranger & thank you so much for bringing so much fun, joy and science into the lab & the @braincircuits.bsky.social!

Why do different studies of brain atrophy in schizophrenia identify different brain regions? New paper by @braincircuits.bsky.social shows these regions are part of one common network. www.massgeneralbrigham.org/en/about/new...

Great Neuroimaging SIG to kick off the last morning at #AES2024 in Los Angeles. Lots of exciting techniques and datasets!

Spectacular talk by @caromenard666.bsky.social on BBB disruptions in MDD focusing on pericytes and presenting female-centered results! 🧠🦹🏼‍♀️ #ACNP2024

Coming to #AES2024? Why spend the last conference day sleeping in when you could come to the Neuroimaging SIG? See you at 7am Dec 10 if you're curious about applications of brain gradients in TLE to understand cognitive and clinical phenotypes! 🌈 🌅

Hey #ACNP2024 👋🏻 First-timer both to ACNP and Phoenix! I am an instructor at @harvardmed.bsky.social and will be presenting my work on the involvement of non-neuronal processes in MDD on Tuesday (T130). Stop by for a chat!🧠 Want a spoiler? Join @nikosdaskalakis.bsky.social talk on Monday at 9:30am ⚡️

Very happy to see this one out in the world 😁 a joint endeavour with Val Kebets 🌟 We used PLS to identify components linking symptoms of psychopathology with multimodal imaging markers in the ABCD dataset Get all the deets 👉 elifesciences.org/articles/87992

Let's talk numbers: To date, since Oct 25th, we have found 395,000 Bluesky posts that link to a research paper or other research object that has a scholarly identifier like a DOI, PubMed ID, URN etc This is enormously high for a platform that has only been open since Feb to general sign-ups.

In case you missed the excellent talk from @fredschaper.bsky.social and Robert Fisher last month, the recording has been uploaded: youtu.be/pjIfTYQkqUE Mark your calendars for the next installment on December 19th with the fantastic @bahnebahners.bsky.social and @allisonwatersphd.bsky.social!

Had a lot of fun writing this news & views article on Converging Cortical Axes with @bogglerapture.bsky.social shorturl.at/LsB5p

Tune in below at 12 EST today if you want to hear all about neuromodulation for epilepsy and Bob’s tips on job searching in academia👏🧠

How can someone lose a part of their vision and not know it? Visual deficits that go unnoticed challenges the view that our conscious experiences are what we know best. We review the surprisingly common phenomena @braincircuits.bsky.social Last day of free access to the full PDF⏱️ t.co/CBBLrhy5sB

Have you ever felt like you're in a surreal world where sizes and scales are all warped? No, it's not a fantasy—it's a real medical condition! Come dive with me into this mind-bending phenomenon called Alice in Wonderland Syndrome (AIWS): onlinelibrary.wiley.com/doi/abs/10.1...

Excited to join Bluesky! I’m an engineer, neurologist, and neuroscientist interested in causal mapping of neurological and psychiatric symptoms to human brain circuits to identify therapeutic targets for neuromodulation. #DBS, #TMS