Super proud that my PhD mentor being awarded the #Burnetmedal at #ASI2025 in Perth, Frank Carbone and the discovery of cross-presentation, and its role in priming killer T cell responses, using his original lecture slides from late 80’s #classicfrank

Joint chromatin accessibility and transcriptomic profiling of human and mouse pancreatic lymph nodes uncovers distinct features of CD4 T cells in T1D @sciimmunology.bsky.social @vahedilab.bsky.social www.science.org/doi/10.1126/...

Are you interested in #type1diabetes research? The Immunology of Diabetes Society Congress in Brisbane, Australia is coming up fast. April 20-24 2026 Abstract submission deadline: January 16h 2026 Early bird registration deadline: March 9th 2026 www.ids2026.com.au @ids-t1d.bsky.social

Excited to share AlphaDIA's publication in Nature Biotechnology! Our open-source DIA framework brings deep learning directly to raw MS data with feature-free processing, transfer learning for any PTM, and performance matching top tools. www.nature.com/articles/s41...

▪️ “There was a time when politicians did not use defamation laws. Most believed they had platform enough to defend their reputations... You & the govt you served in played a big role in changing that. Imagine the consequences.” - Sat Paper Editorial ⤵️ www.thesaturdaypaper.com.au/share/21849/...

As screening and early treatment for type 1 #diabetes become more widespread, the European action for the Diagnosis of Early Non-clinical Type 1 diabetes For disease Interception (EDENT1FI) consortium highlights the need for clearer, more consistent terminology www.thelancet.com/journals/lan... #T1D

A new soft plastics recycling scheme is replacing Australia’s failed REDcycle. Will it mean consumers have to pay more?

🚨 The US government has stopped the funding PubMed, one of the most comprehensive databased of biomedical literature. Try using Europe PMC (europepmc.org) — the European alternative to PubMed with 46M+ articles.

#JaneCaro comments on the absurdity that sees all taxpayers fund private schools while underfunding public schools @janecaro.bsky.social Gift article #Auspol failure #AusLabor fail www.thesaturdaypaper.com.au/share/21678/...

In The Lancet @thelancet.com: Minimum effective low dose of antithymocyte globulin in people aged 5–25 years with recent-onset stage 3 type 1 #diabetes (MELD-ATG): a phase 2, multicentre, double-blind, randomised, placebo-controlled, adaptive dose-ranging trial www.thelancet.com/journals/lan... #T1D

Prediction of progression to type 1 #diabetes with dynamic biomarkers and risk scores thelancet.com/journals/lan... #T1D #MedSky #EndoSky

Video circa 2022.... #auspol

Want to hear all the latest #type1diabetes research? Registration has now opened for the 2026 Immunology of Diabetes Society Congress @ids-t1d.bsky.social www.ids2026.com.au

Disasters are multiplying & the costs are set to skyrocket. The ADF is already stretched, & shouldn't be asked to carry this burden. We need to decide who pays for disaster relief: ordinary Australians, or the fossil fuel industry fuelling the damage? www.abc.net.au/news/2025-09...

Straight to the Pool Room.📌 Excellent explainer on immigration and housing. #auspol www.thenewdaily.com.au/opinion/2025...

Just maybe we need a campaign to reform education. At a time when we all face a huge social upheaval to #transition the #economy, trashing the arts and social sciences and making them inaccessible will only benefit Shell, Santos and Woodside as a delaying tactic. #auspol @jasonclaremp.bsky.social

Interesting report that I missed from last year detailing just how dire R&D funding has gotten in Australia. ~15years of cuts have left us so far off the pace its embarrassing. go8.edu.au/wp-content/u...

Superb science journalism from @nature.com on a handful of bad editors driving most retractions. This was always a concern for mega journals, where editorial oversight quality varies wildly - this report puts names and numbers on the problem. www.nature.com/articles/d41...

Important first-in-human report today for donor pancreatic islet beta-cell transplant to an individual w/Type 1 diabetes. With genome editing, there was no immune response induced or need for immunosuppression. Major implications for transplantation in general @nejm.org www.nejm.org/doi/pdf/10.1...

The ancestral protein of the CRISPR–Cas9 system — less than half the size of its famous descendant — is engineered into an effective DNA-targeting tool that can be delivered by AAV as an epigenome editor for in vivo gene silencing #NBTNV go.nature.com/43JRgno rdcu.be/eyorl

Why working less could be better for you — and your employer www.sbs.com.au/news/article...

Good to see reports on this finally out…we need an independent science watchdog to prevent this happening again. The cage, the camera and the con: How a superstar scientist was finally caught out - The Age

"Transmission of maternal oral pathobionts to the infant gut predisposes offspring to exacerbated enteritis" http://dlvr.it/TM6rrb Hiroko Nagao-Kitamoto Nobuhiko Kamada @cp-cellreports.bsky.social

I reviewed this paper a bit ago and have been waiting for it to come out. A great resource for us Bifidobacteria researchers!

If NIH shuts down funding of animal-only grants, get ready for a whole lot of grants to include some pointless organoid experiments just to qualify. What a terrible rule! www.drugdiscoverytrends.com/nih-announce...

Just out in @theconversation.com Melting ice will strengthen the monsoon in northern Australia – but cause drier conditions north of the Equator theconversation.com/melting-ice-...

Latest from my lab: We used CRISPR to knockout PD-1 from islet-specific CD4+ T cells, and show that bystander suppression of islet-specific CD8+ T cells is disrupted, accelerating autoimmune diabetes #type1diabetes #tolerance doi.org/10.1111/imcb...

Earth is trapping much more heat than climate models forecast – and the rate has doubled in 20 years theconversation.com/earth-is-tra...

👩‍💻 We’re hiring! Lê Cao Lab at Uni Melbourne @mig-unimelb.bsky.social needs an R dev to power the next-gen of mixOmics 🚀 Love #RStats, #Bioconductor & multi-omics? Help expand mixOmics, run workshops & publish cutting-edge methods. Apply: unimelb.wd105.myworkdayjobs.com/en-US/UoM_Ex...

What an amazing time to be a biomedical scientist. www.nejm.org/doi/abs/10.1...

Join #MVIF 40 cassyni.com/s/mvif-40 and #MeetTheSpeakers 🇺🇸 @michaelwasney.bsky.social who will talk on Uniform bacterial genetic diversity along the guts of mice inoculated with human stool.

I'm looking for a new postdoc interested in #bioinformatics, #microbiome, and the role of early life events in initiation of autoimmune #type1diabetes

Back when I started studying science governance I never imagined “destroying the world’s leading funder of biomedical research because you’re mad they don’t endorse your fringe COVID theories” would not only be a mainstream policy position but comprise 2/3 of the president’s budget proposal for NIH.

The President’s entire budget proposal destroys the state as we know it, and not in any kind of liberatory way. Here are the proposed NIH & NSF cuts. There will be no coming back from this.

Enjoying the taste of my democracy sausage. #AustraliaVotes

www.uq.edu.au/news/article... #type1diabetes #microbiome

Check the #AISG2025 speaker lineup! 🤩 Prof Jim Johnson Prof Jenny Gunton Prof Shane Grey A/Prof Tracey Putoczki Prof Anand Hardikar A/Prof Sumaira Hasnain Prof Wayne Hawthorn Professor Henry Pleass A/Prof Luciano Martelotto @jimjohnsonsci.bsky.social @lgmartelotto.bsky.social

My lab's latest research out now published with @springernature.com in Nature Communications. www.nature.com/articles/s41... We show that a short-chain fatty acid delivering biotherapy given to adults with #type1diabetes remodeled the gut barrier and #microbiome function.

Pubmed

Looks to me as if the entire NIH site is missing? 😟 Working my way up, PubMed can’t be found (the browser can’t connect to it ⬇️); nor can the parent site, the National Library of Medicine (NLM); nor the NIH main site.

What Trump miscalculates about American power www.thesaturdaypaper.com.au/news/interna... via @thesaturdaypaper.com.au The most important piece I have read since Trump’s re-emergence. The bullying of Zelensky at the White House vindication of Wesley’s analysis.

More attacks on US science by stealth as new research grants still frozen! Grants issued via 2 step process- one to assess science via science board and one a grant review step with a membership of a wider board that get final approval to sign the money of based upon initial recommendation 🧪🧵

1. Today the NIH director issued a new directive slashing overhead rates to 15%. I want to provide some context on what that means and why it matters. grants.nih.gov/grants/guide...

Sounds great if it’s accompanied by increased funding. For the past decade or so funding for research in Oz has stagnated, when factoring inflation it’s going backwards. Flooding more people will likely push the system to collapse. Eg www.theguardian.com/business/202...

Opinion | "The harsh lesson of this term of Parliament is that no major-party government can be trusted to take real climate action," writes @keanebernard.bsky.social. www.crikey.com.au/2024/11/28/l...

Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve #gender #equality? We discuss various strategies in this #Cell Commentary #WomeninSTEM www.cell.com/cell/fulltex... 🧵 1/