Application of continuous glucose monitoring & automated insulin delivery technologies for pregnant women with type 1, type 2, or gestational diabetes: an international consensus statement www.thelancet.com/journals/lan... #FREE to read with registration (also FREE) #MedSky #EndoSky #WomensHealthSky

Male #hypogonadism is a clinical syndrome of impaired androgen production from the testes that is usually associated with impaired spermatogenesis and subfertility www.thelancet.com/journals/lan... #testosterone #MensHealth #MedSky #EndoSky #MensHealthSky

According to the 11th edition IDF Diabetes Atlas, an estimated 11·11% of adults worldwide were living with diabetes in 2024, and the prevalence is expected to reach 12·96% by 2050 www.thelancet.com/journals/lan... #FREE to read with registration (also FREE) #MedSky #EndoSky

Endocrine complications occur in 40–60% of survivors of cancer and include hypothalamic–pituitary disorders, dysregulation of steroid and peptide hormones, and dysregulation of bone and metabolism www.thelancet.com/journals/lan... #OpenAccess #MedSjy #EndoSky #OncSky

Although #weightloss in people with #obesity has many health benefits, it can also have adverse #skeletal effects, with increased #bone loss and #fracture risk www.thelancet.com/journals/lan... #osteoporosis #BoneHealth #diets #exercise #BariatricSurgery #GLP-1 receptor agonists #MedSky #EndoSky

Regulation of #endocrine #tumours by aberrant GPCR is not restricted to cortisol-secreting adrenal lesions, but also occurs in tumours of several other organs www.thelancet.com/journals/lan... G-protein coupled receptors #GPCRs

People with type 2 #diabetes are likely to be more susceptible to adverse health effects from PM2·5, which further amplifies #pollution-related #cardiovascular risk www.thelancet.com/journals/lan... #T2D #AirPollution #CardioMetabolicHealth #MedSky #EndoSky

Although very infrequent, cases of #hypothalamic #obesity are a challenging, often intractable medical condition, that can also help to elucidate mechanisms of obesity and eventually identify therapeutic targets www.thelancet.com/journals/lan... #hyperphagia #MedSky #EndoSky

Substantial progress has been made to ensure that women with any type of #diabetes have healthy #pregnancies, with therapeutic advances including #insulin analogues and continuous glucose monitoring (#CGM) technologies www.thelancet.com/journals/lan... #T1D #T2D #GDM #FREE to read w/reg (also FREE)

Quarterly dosed #zodasiran shows evidence of reductions in #LDL #cholesterol with a favourable safety profile, in patients with #HoFH receiving background lipid-lowering therapy www.thelancet.com/journals/lan... #homozygous #familial #hypercholesterolaemia #MedSky #EndoSky #CardioSky

The hypothalamic–pituitary–thyroid axis plays a crucial role in the pathogenesis, diagnosis, risk stratification, effectiveness of radioiodine therapy, & treatment response evaluation in epithelial #thyroid #cancer www.thelancet.com/journals/lan... #thyroidcancer #HPT axis #MedSky #EndoSky #OncSky

The combined action of #TKIs on #thyroid gland function & peripheral deiodinases generates a unique phenotype of primary #hypothyroidism characterised by increased TSH concentrations & a reduced T3 to T4 ratio www.thelancet.com/journals/lan... #tyrosine #kinase #inhibitors #thyroidcancer #EndoSky

#Adrenocortical #carcinoma is a rare malignancy, in contrast to benign #adrenal tumours, which are among the most common human neoplasias with a prevalence of greater than 3% in adults older than 50 years www.thelancet.com/journals/lan... #ACC #OpenAccess #MedSky #EndoSky #OncSky

Multiple endocrine neoplasia type 1 (#MEN1) is characterised by combined occurrence of #parathyroid tumours, #duodenopancreatic #neuroendocrine tumours, and anterior #pituitary adenomas thelancet.com/journals/lan... #MEN1 #FREE to read with registration (also FREE) #MedSky #EndoSky #OncSky

Our #MostRead article in 2025: Definition and diagnostic criteria of #clinical #obesity www.thelancet.com/journals/lan... #FREE to read with registration (also FREE) #MedSky #EndoSky

Adrenal tumours are commonly encountered in every endocrinology practice and related subspecialties nowadays, and require the most accurate evidence-based management, treatment, and follow-up www.thelancet.com/journals/lan... #adrenal #tumours #MedSky #EndoSky #OncSky

#Hyperprolactinaemia can result from physiological causes, pharmacological agents, or pathological conditions such as #prolactin-secreting #pituitary adenomas and other pituitary stalk-compressing masses www.thelancet.com/journals/lan... #prolactinomas #MedSky #EndoSky #OncSky

The increasing occurrence of euglycemic diabetic ketoacidosis (#DKA), with glucose concentrations below established diagnostic thresholds, makes the availability & use of continuous ketone monitoring (#CKM) technology an important addition to the #diabetes management toolkit tinyurl.com/zs45wamw .

Achieving #normoglycaemia parallels established strategies in other cardiovascular risk conditions—such as normalising blood pressure in hypertension or lowering elevated cholesterol in hypercholesterolemia—to prevent cardiovascular events and death www.thelancet.com/journals/lan... #OpenAccess

📢 CALL FOR PAPERS! In collaboration with the International Diabetes Federation—Western Pacific Congress, jointly held with Australasian Diabetes Congress 2026, we invite ORIGINAL RESEARCH on innovation in #diabetes prevention, diagnosis, management & #stigma reduction in the region. #EndoSky

New Hypothesis—Amylin and the renin-angiotensin system: risk or opportunity in amylin-based therapy? spkl.io/63329AYEvx

Among our most-read in 2025 ⤵️ Ultra-processed foods – what’s the impact? In a Lancet Series, experts warn a global rise in #UPFs presents a growing public health threat. Read the evidence & policy recommendations ⬇️ spkl.io/63323AYDz7

For much of the 20th century, the diagnosis of #adrenal #tumours, defined as enlarged or atypical-appearing adrenal lesions that can be benign or malignant, relied on clinical suspicion of large palpable masses, hormonal manifestations, or autopsy findings www.thelancet.com/journals/lan... #EndoSky

Severe #glucocorticoid-induced #osteoporosis requires a long-term sequential treatment approach consisting of a bone-anabolic agent followed by an antiresorptive drug www.thelancet.com/journals/lan... #BoneHealth #BMD #fractures #OpenAccess #MedSky #EndoSky #RheumSky

In 2024, one in nine adults worldwide was living with diabetes. The number of adults with #diabetes in 2024 exceeded 500 million and is projected to rise to close to 900 million by 2050 www.thelancet.com/journals/lan... #FREE to read with registration (also FREE) #MedSky #EndoSky

The recommendations in this Consensus Statement emphasise the value of #CGM during #preconception and #pregnancy for women with pregestational type 1 #diabetes in reducing pregnancy complications www.thelancet.com/journals/lan... #T1D #T2D #GDM #FREE w/reg #MedSky #EndoSky #WomensHealthSky

New—Zodasiran, an RNAi therapeutic targeting ANGPTL3, for treating patients with #homozygous #familial #hypercholesterolaemia (GATEWAY): an open-label, randomised, phase 2 trial thelancet.com/journals/lan... #HoFH #MedSky #EndoSky #CardioSky

Targeting individuals at high genetic risk of type 1 #diabetes could facilitate efficient screening and identification of presymptomatic type 1 diabetes, helping better inform the natural history of the disease in adults www.thelancet.com/journals/lan... #T1D #FREE to read #MedSky #EndoSky

The global rise in type 1 diabetes cases, combined with limited paediatric type 1 #diabetes services due to resource constraints & a shortage of trained specialists in some LMICs, highlights the need for novel approaches to strengthen & enhance care www.thelancet.com/journals/lan... #FREE to read

New—Application of continuous glucose monitoring & automated insulin delivery technologies for pregnant women with type 1, type 2, or #gestational #diabetes: an international consensus statement thelancet.com/journals/lan... #T1D #T2D #GDM #CGM #AID #FREE to read w/reg (also FREE) #MedSky #EndoSky

Staging #prediabetes and type #2 diabetes: the time to start is now www.thelancet.com/journals/lan... #T2D #MedSky #EndoSky

The anticipated availability of continuous ketone monitoring (CKM) has the potential to reduce the risk of developing diabetic ketoacidosis (#DKA), one of the most life-threatening acute complications of type 1 and type 2 #diabetes www.thelancet.com/journals/lan... #T1D #T2D #MedSky #EndoSky

According to the 11th edition IDF Diabetes Atlas, an estimated 11·11% of adults worldwide were living with diabetes in 2024, and the prevalence is expected to reach 12·96% by 2050 thelancet.com/journals/lan... #diabetes #FREE to read with registration (also FREE) #MedSky #EndoSky

Acute kidney injury (AKI) is a common and important complication of major surgery, yet recommended preventive care is rarely administered. A new study investigated the effectiveness of a preventive care strategy to reduce moderate or severe AKI after major surgery: spkl.io/63321Ai4Fl

Ageing is associated with cognitive decline & an increased risk of neurodegenerative diseases. A Review explores the neuroprotective mechanisms of endurance exercise & highlights the importance of cardiorespiratory fitness in healthy brain ageing: spkl.io/63323Aia89

New—11th edition of the IDF Diabetes Atlas: global, regional, and national diabetes prevalence estimates for 2024 and projections for 2050 thelancet.com/journals/lan... #diabetes #FREE to read with registration (also FREE) #MedSky #EndoSky

Metabolic dysfunction-associated steatotic liver disease: heterogeneous pathomechanisms and effectiveness of metabolism-based treatment www.thelancet.com/journals/lan... #MASLD #obesity #lipodystrophy #OpenAccess #MedSky #EndoSky #LiverSky

Definition and diagnostic criteria of clinical obesity www.thelancet.com/journals/lan... #clinical #obesity #FREE to read with registration (also FREE) #MedSky #EndoSky

Incretin hormones—glucagon-like peptide-1 (GLP-1) & glucose-dependent insulinotropic peptide (GIP)—act as a critical link connecting #digestion, #metabolism, & #cardiovascular function, supporting physiological adaptations to nutrient intake thelancet.com/journals/lan... #incretins #MedSky #EndoSky

Prediabetes remission is a distinct and actionable endpoint that redirects the disease trajectory towards health, rather than merely slowing the decline to β-cell dysfunction and type 2 diabetes www.thelancet.com/journals/lan... #prediabetes #remission #FREE to read with registration (also FREE)

Reaching #prediabetes #remission is linked to a decades-long benefit, halving the risk of #cardiovascular death or hospitalisation for heart failure in diverse populations. Targeting remission might represent a new approach to cardiovascular prevention www.thelancet.com/journals/lan... #OpenAccess

Heterozygous familial hypercholesterolemia is a common genetic condition characterised by high LDL cholesterol levels from a young age. A Review in @thelancetendo.bsky.social discusses the latest knowledge familial hypercholesterolaemia & its unmet clinical needs: spkl.io/63320AiBFu

Individuals on long-term oral #glucocorticoid treatment display an estimated prevalence of #osteoporosis or fractures as high as 30–50%, rendering glucocorticoid therapy the most common cause of secondary and iatrogenic osteoporosis thelancet.com/journals/lan... #MedSky #EndoSky #RheumSky

With more people with type 1 #diabetes living into older adulthood, new research and clinical-care models that consider multiple important life stage transitions and their effect on type 1 diabetes care and self-management are needed www.thelancet.com/journals/lan... #T1D #MedSky #EndoSky

In adults with #islet #autoantibody positivity, the lower risk of progression to type 1 #diabetes compared with children, combined with the high background prevalence of mild non-autoimmune dysglycaemia, presents substantial challenges for clinical management www.thelancet.com/journals/lan... #T1D

The prevalence of overweight and obesity in China has continued to increase over the last decade, with mounting health and economic consequences www.thelancet.com/journals/lan... #obesity #China #MedSky #EndoSky

New in the January Issue: Continuous ketone monitoring for people with #diabetes: international expert recommendations on the application of a new technology www.thelancet.com/journals/lan... #FREE to read with registration (also FREE) #MedSky #EndoSky

New in the January Issue: Task shifting and task sharing in paediatric type 1 #diabetes care: a global survey www.thelancet.com/journals/lan... #T1D #FREE to read #MedSky #EndoSky

New in the January Issue: Genetic risk-targeted islet autoantibody screening for presymptomatic type 1 #diabetes in adults www.thelancet.com/journals/lan... #T1D #FREE to read #MedSky #EndoSky

New in the January Issue: Staging #prediabetes and type 2 #diabetes: the time to start is now www.thelancet.com/journals/lan... #T2D #MedSky #EndoSky