🦠 Mycobacteria aren't just tough, they're interior designers! 🦠 Check out our latest #preprint 🚨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity 🤫 Thread coming soon!

🇪🇺 Smooth publishing experience with #microLife, the new @femsjournals.bsky.social journal of the European Academy for Microbiology. 🙏 @erc.europa.eu, F.R.S-FNRS & WEL-RI for support 4/4

🚨New paper out! #MicroSky Studying obligate predators like Bdellovibrio bacteriovorus is tricky—essential genes for predation are also essential for survival. We expanded its genetic toolbox: 🧬promoters to fine-tune expression 🧬IPTG-inducible system 🧬CRISPRi for rapid knockdown bit.ly/46GUn2c 1/4

So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!

New preprint in the lab! How the mitochondrial ETC works during infection of human macrophages with #Legionella or #Salmonella? Spoiler: there are some similarities and also pathogen-specific differences. Work led by Francisco Garcia and Paula Martínez, with @cbuch.bsky.social at @pasteur.fr

🔬 We’re past the midpoint of the year; perfect time to look back at what’s been discovered so far. From how Salmonella slows its escape from immune cells to the microbes thriving in oil reservoirs, these are the most-read #microLife papers of 2025 so far: buff.ly/TfhOvEc

I was very honored to receive on of the Poster prizes at FEMS MICRO 2025 in Milan a few weeks back. It was such a great conference, heard so many interesting and stimulating talks & poster discussions.

Avirulent Pseudomonas aeruginosa T3SS-negative strains belonging to Clade 5 produce variable quantities of secondary metabolites @femsjournals.bsky.social #microLife from @inaattree.bsky.social with @cbuch.bsky.social academic.oup.com/microlife/ad...

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Congratulations to 2025 GRC Microbial Adhesion and Signal Transduction Poster Award Winners!! 🎆🥂🙌 Thank you @cp-cell.bsky.social and @femsmicro.org for sponsoring! From, Your secret judges 🤫

Congratulations @cbuch.bsky.social ! 👏

FEMS MICRO Milan 2025 is off to a great start with Prof. Carmen Buchrieser presenting her keynote on Legionella pneumophila and the fascinating ways this pathogen mimics eukaryotic cells.

What an inspiring first day at FEMS MICRO Milan! We heard from FEMS Pres. Antonio Ventosa at the Opening while former Pres. Hilary Lappin-Scott helped connect new attendees. Thanks to keynotes Profs. Carmen Buchrieser and Gian Rossolini for sharing their expertise. #FEMS2025

One of the most controversial sessions of the @femsmicro.org Congress—run by Malick Gibani—deals with the so-called *Human challenge studies* of pathogens ie deliberate inoculation of human subjects with virulent agents. The benefits are clear but … is informed consent enough 🤔?

Four leading researchers on bacterial computing in the @femsmicro.org Workshop on the the topic during the Congress—quite amazing talks by @angelgm.bsky.social, Yolanda Schaerli, Manish Kushwaha & Samgram Bagh. Do bacteria compute? Can we make them to compute wth our logic or do they have their own?

At my 1st @femsmicro.org congress (in Milan!) - it's a fantastic meeting. I co-chaired a superb session on Microbial Dark Matter with @jlewillett.bsky.social, who also kicked off the session with a talk on her lab's work. 🤩 We also heard from my FEMS Microbes co-EIC Kathleen Scott! 💪🏽 #FEMS2025

Delighted to have contributed to this fascinating paper led by Prof. Timmis on how helpful microbes can be for humanity at different scales! "The future is not set. There is no fate but what we make for ourselves". -John Connor (Terminator) @microbiotech.bsky.social

New preprint from the lab!! Check it out!

New mini-review on the respiratory microbiome and its contribution to human health from biotechnology 🫁🦠 @tmcoque.bsky.social @microbiotech.bsky.social enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...

Congratulations to @cbuch.bsky.social on the FEMS-Lwoff Award!!! Well-deserved ❤️#FEMS2025

ᑎEᗯ IᑎᑎᗩTE IᗰᗰᑌᑎE EᖴᖴEᑕTOᖇ! Anaya-Sanchez et al Infected macrophages switch to aerobic glycolysis, generating toxic METHYLGLYOXOL Bacteria lacking detox enzyme 𝘨𝘭𝘰𝘈 become highly mutagenic, lose virulence Boosting methylglyoxal helps control 𝘓𝘪𝘴𝘵𝘦𝘳𝘪𝘢 or TB infection www.cell.com/cell-host-mi...

🎶 Straight from the Lab to the Mic: when a Pasteur scientist turns her thesis into a rap 🎶 #FeteDeLaMusique

www.biorxiv.org/content/10.1.... New pre-print of the lab in which we dive deep into Klebsiella-macrophage interface. High structural resolution of the lipid A produced by Klebsiella within the Klebsiella containing vacuole governed bt TLR4 signaling. Superb job led PhD student Toby Bartholomew

Isabel from the BacDive Team will be at the @leibniz-dsmz.bsky.social booth at #FEMS2025 🦠 to answer your questions on #DSMZDigitalDiversity 🖥️🧬 databases.

Thrilled that our latest paper showing that DCs undergo either pyroptosis or apoptosis upon bacterial blockade of host translation to restrict Legionella is now online at the @asm.org journal mBio! Congrats to 1st author @vvazquez.bsky.social & co-authors! 🎉 journals.asm.org/doi/10.1128/...

🧬 Don’t miss the inspiring keynote by Manu Prakash about #frugalscience and #innovation, renowned biophysicist and innovator during our Adapting to Change conference 👇 @pasteur.fr @prakashlab.bsky.social @ibeidlabex.bsky.social www.labexibeid.fr/en/keynote-m...

🌍Explore the frontlines of global health with Peter Hotez! A must-watch conference on vaccines and infectious disease challenges. Dive into the science shaping our world 👇 @pasteur.fr @ibeidlabex.bsky.social www.labexibeid.fr/en/ibeid-pet...

Let’s start our 14th edition of the Labex Day with a keynote lecture by @drrachellowe.bsky.social on how to improve surveillance, preparedness and response to climate-sensitive disease outbreaks & emergences. @ibeidlabex.bsky.social @pasteur.fr @bastinlab.bsky.social @salehlabparis.bsky.social

@cristancholina.bsky.social, laureate of our last call for proposals, is now presenting her work on modeling the spread of Chikungunya in Réunion island. @scauchemez.bsky.social @institutpasteur.bsky.social

Mathilde Gendrin, IBEID junior group, has joined us from Institut Pasteur de la Guyane to present her work on the role of the microbiota in mosquito physiology. @institutpasteur.bsky.social

Very interesting results by Nathan Ribot on the identification of a novel type of Plasmodium oocystes division. @institutpasteur.bsky.social

We conclude our morning sessions with Isabelle Louradour, S2I IBEID fellow, guiding us through her results on how Leishmania and Sauroleishmania hybridization can inform on parasite genomic compatibility and transcriptomic adaptation. @pasteur.fr

We are now moving to Mycobacterial phenotypic variation with Giulia Manina, formerly supported as an IBEID junior group. @institutpasteur.bsky.social

Let’s move to TBEV pathogenesis and neurological outcomes using innovative mouse models with our Seed Grant laureate Caroline Manet. @institutpasteur.bsky.social

Elena Capuzzo, PhD student selected for an End of thesis extension, is now presenting her results on controlling Staphylococcus aureus infection by cold atmospheric plasma in skin burn wound models. @institutpasteur.bsky.social @00capu.bsky.social

Adeline Mallet, head of the Ultrastructural Bioimaging facility, is presenting cutting-edge technologies to visualize intraflagellar transport in Trypanosomas. @pasteur.fr @bastinlab.bsky.social

How to prime mosquito immunity with fungus? A potential strategy to reduce vector competence by Christian Mitri, group leader in Anna-Bella Failloux research unit. @pasteur.fr

Gaelle Gonzalez is now presenting her One Health project to diagnose West Nile and Usutu in Nouvelle-Aquitaine and how the IBEID Emergency Action funding she received cross link with her recently obtained PEPR PREZODE. @anses-fr.bsky.social @pasteur.fr @prezode.bsky.social

Mehdi Khelfa, laureate from our last call for proposals, now presenting his recent results on plasmacytoid DC heterogeneity upon HIV infected CD4 T cell stimulation. @pasteur.fr @institutcochin.bsky.social

A pleasure to have @fernando-batista.bsky.social, IBEID’s grantee from @gloverlab.bsky.social , presenting his project on the dynamic relationship between Trypanosoma brucei and the tsetse fly. @pasteur.fr

New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...

📢🔬 Unlock Your Potential at FEMS MICRO Milan🌟 Wind down after a day of scientific sessions at our Poster Networking Reception. This is your chance to stand by your poster & discuss your findings, enjoy refreshments, & explore the scientific research. ➡️ Register today buff.ly/6f7yHDV

Prepare to be inspired and discover the new FEMS MICRO Milan 2025 day-to-day programme: buff.ly/eyLAber Designed to go beyond traditional presentations, this year’s programme offers interactive opportunities to exchange ideas and spark collaborations. #FEMS2025

Both mushrooms on your plate and the tangled cables behind your computer use electric currents along "wires" to transfer signals. ⚡ This #FEMSmicroBlog explains how fungi transmit electrical signals within their hyphal networks and the challenges to study them. #FascinatingMicrobes buff.ly/V8kBKO4

🦠 Bacteria and archaea fine-tune CRISPR immunity by silencing ‘extraneous’ CRISPR RNAs (ecrRNAs) that could sabotage defense. Weinberg’s lab @UniLeipzig & @BeiselLab reveal 3 strategies in type II-C systems that mitigate ecrRNAs and maintain precision. ✂️🧬 buff.ly/xcSOMpG

In the #Archaea H. volcanii, Marchfelder lab deleted all 4 #proviruses (∆Halfvol1–4) and found: ⬆️ Swarming & chemotaxis ⬆️ H₂O₂ resistance ⬆️ Cell elongation ⬇️ CRISPR expression Turns out, these proviruses are active and likely cause chronic infection!🧬🦠 buff.ly/SSXPfdz

I will be recruiting new postdocs with start dates end 2025 - early 2026. If you'd like to work at the Pasteur Institute in the heart of Paris surrounded by amazing scientists, reach out to discuss possible projects on SynBio / Bacterial Immunity!

Marie Curie fellowship, post-doc hosting oppotunity in my lab. MSCA Post-doctoral Fellowship at IBPC Paris on RNA modifications in bacteria (FRANCE) 🦠💫 euraxess.ec.europa.eu/jobs/hosting...

Our latest paper is out! Congratulations to @leaswistak.bsky.social et al for this amazing #cryoET work that elucidates the initial stages of #T3SS dependent vacuolar damage during #Shigella infection. We will do a deep-dive later! journals.plos.org/plosbiology/...

New postdoc position in our lab (2 y+): evolutionary genomics of integrons and MGEs with focus on vibrio-phage interactions. Great environment @pasteur.fr for science, career building. Super collaborators @celineloot.bsky.social @amazeld.bsky.social @fredoleroux.bsky.social 3 weeks to apply!