Nothing else to say.

My painting HELENA VALLEY

Interesting: onlinelibrary.wiley.com/doi/abs/10.1... do we want an agonists or antagonist of this receptor for pain? My assumption had always been antagonist but maybe that is wrong.

People get uncomfortable thinking about disability justice because they don't like to admit that if you live long enough, you will become disabled. Your body will operate in a way not conformed to by our built environment, and that's really all disability is.

Very proud of our group’s showing at #USASP2026! Thank you to the organizers of this fantastic meeting! @usasp.bsky.social @karapedsgastrodoc.bsky.social @sdavidson.bsky.social @sarahanajjar.bsky.social @yylab.bsky.social @goinsyeah.bsky.social @pazduran.bsky.social @keylinesc.bsky.social

During my undergraduate, I wrote many essays detailing Benjamin’s adamance to virtuous academic-ship. His view of the world still rings true.

my favorite thing is learning something new. my second favorite thing is telling everyone in earshot about it.

NEW PREPRINT 🚨 Why does IBS pain persist? PRC’s Nestor Jimenez-Vargas and the Bunnett Lab uncover how PAR2 signaling from endosomes amplifies fleeting histamine signals to sustain colonic nociceptor hyperexcitability. www.biorxiv.org/content/10.6... @badrsokrat.bsky.social

Gut health finally has a scientific definition. ISAPP’s new consensus defines it as normal GI function without disease or symptoms that affect quality of life. @karapedsgastrodoc.bsky.social www.nature.com/articles/s41...

Thanks @nbcnews.com for covering our #SciImmunoloy paper showing the role of IL-10+ monocytes in sex difference in #pain www.nbcnews.com/health/women... #neuroimmunology Original article in comments

Up close and personal with a branching neurite in a DIV2 hippocampal neuron expressing FTractin-GFP. This was imaged every 6 seconds over 10 minutes on the trusty @zeiss-microscopy.bsky.social LSM880. Happy #FluorescenceFriday

Worth a read: de-siloing research is critical for understanding brain function, brain health and innovative treatment and repair paradigms- as noted here, to do so means it’s critical to utilize observed differences and concordance between species and studies #neuroskyence #glia

Thrilled that my paper is out in the @nature.com. We explored how the brain builds complex tasks by compositionally combining simpler sub-task representations. The brain flexibly performs multiple tasks by dynamically reusing neural subspaces for sensory inputs and motor actions rdcu.be/eRVUk

On the cover of Science Signaling! Work in the Ye lab, led by Naijiang Liu and Xiaojie Shi, shows that blocking epidermal growth factor receptor signaling reduces oral cancer pain AND boosts opioid efficacy. www.science.org/doi/10.1126/...

New paper alert!🤩Super proud that our story led by superstar postdocs @liujinghui.bsky.social and @nerlielisa.bsky.social is finally out! We found how electrical signals are key for promoting organ regenerative growth!!! A thread 🧵https://www.science.org/doi/10.1126/sciadv.aec0687

Have you seen Xu et al’s results in @nature.com that mitochondrial transfer from glia to neurons protects against peripheral neuropathy? bit.ly/46hu5D2 Come discuss this article with @IASPpain’s @NeuPsig and moderator Courtney Bannerman on 18 Feb #journalclub #painresearch

Distinct activation thresholds of unmyelinated C-fiber afferents by dorsal root ganglion and peripheral nerve stimulation https://www.biorxiv.org/content/10.64898/2026.02.02.703367v1

A Multiscale Model of Collective Decision-Making in Hybrid Aspen Tree Tissues Describes Bud-Dormancy Break https://www.biorxiv.org/content/10.64898/2026.02.04.703817v1

Latest preprint from our lab reports that the distinct pH of anterograde (less acidic) and retrograde (more acidic) lysosomal vesicles in the axon depends on assembly of the V1 and V0 domains of the vacuolar H+ ATPase, mediated by the metazoan RAVE complex www.biorxiv.org/content/10.6...

The new glutamate indicators were announced today in @natmethods.nature.com. 🔗 www.nature.com/articles/s41...

In this week’s #PAIN Featured Image, Gomez et al. describe how the SARS-CoV-2 nucleocapsid (N) protein enhances pathological pain through NaV1.7 modulation. Learn more at bit.ly/4piitaH

Day 16 #artAdventCalendar the woman who figured out why lead is particularly stable & 2nd woman to win the Nobel Prize for #physics 🧪🐡👩🏼‍🔬🎢 #histsci: German-American theoretical #physicist Maria Goeppert Mayer (1906-‘72). As the series of increasingly large atomic nuclei grows with additional nucleons🧵

“Basic neuroscience hasn’t produced new drugs.” 💊 Not true - zuranolone (PPD), suzetrigine (pain), gepants (migraine), and more... were born out of a long arc of studies in the lab. I wrote a Perspective on why this matters. @thetransmitter.bsky.social www.thetransmitter.org/drug-develop...

This is one of those stories where every interview had me like 🤯🤯🤯. For @nature.com Outlook, I dove into the surprising field of cancer neuroscience. Edited by the amazing @scchak.bsky.social www.nature.com/articles/d41... #neuroskyence

The study shows how individual fingerprint ridges deform when we touch different textures, revealing how subtle stretching and shifting along the ridge flanks may drive our remarkably fine tactile sensitivity. buff.ly/4z67Vf1

🧠 We're hiring! 🧠 Are you passionate about neuroscience and education? Join our faculty at UNC Chapel Hill to inspire and teach the next generation of neuroscientists. Apply now: 🔗​​https://unc.peopleadmin.com/postings/308455 #Neuroscience #TeachingJobs #AcademicJobs #HigherEd

Robots don’t just “think”—someone codes their brain. AI doesn’t “learn”—people design its rules. If we want these systems to be just, fair, and brilliant, we need diverse coders shaping the algorithms. #STEMEducation #Robot #Robotics #NoireSTEMinist #STEMForAll #CSEdWeek #CSPowersAI #STEAM

A new blog about our recent three publications on the Nociceptive Apparatus Paradigm #painresearch #physio #neuroskyence painlosophy.wordpress.com/2025/12/06/t...

Read yet another review today that ascribes GECIs' larger SNR vs GEVIs to their being evolved earlier (suggesting the GECIs are better optimized). This assumption is understandable but incorrect. GEVIs' photonic response per molecule per AP have been as good as GECIs since ASAP3.

Fantastic thread on voltage vs calcium imaging. Via photon flux change per molecule per action potential, they’re similar. What makes voltage imaging so much harder, then? Integration time (EPSPs/APs are short), lim ability to jam GEVIs into membrane, and small size of subthreshold Vm changes. 🧪🧠🤖

PRC’s very own Associate Director, Steve Davidson, PhD, took the spotlight as our Keynote Speaker at the 1st NYC Area Pain Research Meet Up! 🎤✨ Talk Title: Humanizing Pain Neurobiology for Translational Gain.

🚀 NAPS applications open this week! The North American Pain School (@napainschool.bsky.social) brings together leading experts in #PainResearch for an immersive #SummerSchool training and networking experience in Québec. 📍 Apply Nov 28–Jan 31 👉 northamericanpainschool.com/registration/

I take on average 10,000 stills and a half hour of video every week. Most I'll never think about again. This I'll hold onto until I grow old. 4 hours ago. Zero edits. No recoloring. No cropping. Nothing. Just straight up reality. 🦑

PhD students and Postdocs: The Night Science Podcast (@nightsciencepod.bsky.social) is producing an episode highlighting young scientists talking about their creative process. DM me if you'd like us to consider you for this, & read below what PhD student Davis Garner will contribute! ⬇️

#BookSky I have not been reading as much as I want lately so big reviews have been on hold. I finished off Haruki Murakami's Dance Dance Dance. Fun to read, it was OK. I tried Hermann Hesse's Steppenwolf. Also, just OK. Maybe it's a sign of growth these literary characters aren't packing a punch. 🤷

Reposting this as a reminder to check back when this book comes out 👍

Pretty exciting to develop simpler, faster ways to target specific neuronal subtypes 🤩 I'm looking forward to seeing this be expanded and integrated in future pain studies ☄️ #PainResearch #Neuroscience #DRG #FACS

🎉 Join the 1st NYC Area Pain Research Meet-Up! 🗓 Fri, Dec 5 | 3–6 PM @nyupainresearch.bsky.social , 433 1st Ave, NY, NY Don’t miss Dr. Steve Davidson’s keynote: “Humanizing Pain Neurobiology for Translational Gain” — plus great company & treats! Registration below 👇 💫 #PainResearch

The Maldives just became the first country to ban tobacco for an entire generation. Anyone born on or after Jan 1, 2007 can never buy or use tobacco — residents and tourists included. www.empr.com/news/maldive....

📢🔬Check out our latest study on the specific role of endocytic mediators in pain-related synaptic transmission, now out in PAIN. @mariafialho.bsky.social #PainResearch #Neuroscience #SynapticTransmission

Help: We have developed an organoid model of diabetic neuropathy. It has oligodendrocytes, myelin, and adding diabetic stimuli makes them lose myelination, and break down mitochondria. Further yet, we show this can be prevented with pharmacological intervention. Which foundations may like this?

Brain-wide single-neuron bases of working memory for sounds in humans https://www.biorxiv.org/content/10.1101/2025.11.10.687666v1

unbelievable

People moan about AI taking people’s jobs, so interact and keep demand high for in person jobs - Go to the post office when you need to renew/post/register things - Go to the bank and get money out - Go to the shops and spend money, stop buying online - Go use public transport - Go to the library

Very grateful to be at the right place and the right time to run alongside a champion. #NYC #NYCMarathon #Legend #Kipchoge

Important announcement 📣 i’m serving face i’m sorry

So true. But then MORE THINGS arrive to get done. And that's just rude.