Shoutouts to @nyupainresearch.bsky.social @vabraira.bsky.social @dr-lupo.bsky.social @sdavidson.bsky.social @karapedsgastrodoc.bsky.social for helping organize!

New research reveals that the gut can sense microbial flagellin via TLR5-expressing neuropod cells, triggering PYY release & reducing feeding through a gut–brain neural circuit—independent of microbiota or immune cues. @karapedsgastrodoc.bsky.social 🔗 www.nature.com/articles/s41...

@chalysthalee.bsky.social did an amazing job presenting at the ISSR! Such a well-deserved travel award and so proud to have her representing the lab!!

A new study shows that food structure plays a key role in determining which gut hormones are released. @karapedsgastrodoc.bsky.social #GLP1 #GutBrainAxis #FoodStructure #Type2Diabetes #ImperialCollege 📖 Nature Metabolism www.nature.com/articles/s42...

🩸 A new blood test (WBAIL-2) detects gluten-triggered IL-2 release, offering a non-invasive, accurate way to diagnose celiac disease, even in patients on a gluten-free diet! 🌾❌ Game-changer for gut health. sciencedirect.com/science/arti... #guthealthmatters #WBAIL2 @karapedsgastrodoc.bsky.social

Excited to share my first senior author paper in Pain! 🎉 We identify Synaptojanin 1 & Endophilin A1 as key endocytic mediators of nociception. Silencing them blocks spinal synaptic transmission and relieves pain in cancer & postoperative models, without affecting normal behavior. buff.ly/caKMGY3

How bad will it be? Catastrophic. Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come. But, this is the WH's *proposed* budget. Speak up now before it is too late. (inflation adjusted $-s below)

🎤 BLINK AND YOU'LL MISS IT: FLASH TALKS AT THE 5TH ANNUAL AMPIRS! ⚡ This year’s Flash Talks were a whirlwind of brilliance 🎤one mic, infinite insight. And WOW, did our presenters deliver! 👏PRC representing! #PRCpride #violetpride #NYUDental #nyuniversity

Round two- ding ding! 🥊 Time for an AMPIRS photo dump that’ll knock your lanyard off 😎🚨poster session 2 coming in 🤳📸 picture perfect!👌

And just like that, AMPIRS takes its final bow! 🎬Huge cheers to our grand finale presenters and a confetti cannon 🎉 of congrats to all the Flash Talk, Poster and Oral Presentation champs! 🏆 You dazzled, you delivered, you definitely deserve it! #PRCpride #MPBpride

Curtains down on AMPIRS! Dr. Nigel Bunnett, our MPB Chair, brought it home with closing remarks. Huge thanks to our amazing sponsors and a special shoutout to MPB for hosting AMPIRS & Welcoming the Pain Research Center into the fun! And now… cue the real research question: Wheres happy hour? 🍹😄

New study! Aging and nerve injury cause senescent neurons in the peripheral nervous system, driving increased pain; targeting these cells could offer a new pain treatment especially in older adults. @vivtawfik-mdphd.bsky.social @karapedsgastrodoc.bsky.social www.nature.com/articles/s41...

IL-18 signaling in epithelial-derived enterochromaffin cells plays a pivotal role in injury response and stem cell activation in the mouse intestine #gutresearch #epithelialcells #IL18 #stemcells @karapedsgastrodoc.bsky.social www.pnas.org/doi/10.1073/...

@karapedsgastrodoc.bsky.social @margolislabnyu.bsky.social @amergastroassn.bsky.social PRC Website: dental.nyu.edu/research/pai... Margolis Lab: dental.nyu.edu/faculty/mole...

Yes! Your taste buds do talk to your brain🧠! Thank you Dr. Nirupa Chaudhari for a fantastic talk! #brain #NYUdentistry #PRC

Tea 🫖 Time ⏰! Happy monthly birthday shoutout! #PRC #NYUdentistry #NYU #MPB 🎂🥳🎈#happybirthday

A new study with Dr. Yi Ye as a co-author "Associations of Pain, Anxiety, and Depressive Symptoms With Sleep Outcomes in Patients with Head and Neck Squamous Cell Carcinoma: A Cross-Sectional Observational Study" #Pain #Anxiety #Depression #HNSCC onlinelibrary.wiley.com/doi/full/10....

Green light for pain relief! 🟢 Researchers found green light therapy reduced osteoarthritis pain in rats, via analgesic endolipids engaging the endocannabinoid system. #PainResearch #GreenLight #Osteoarthritis journals.lww.com/pain/fulltex...

🚨Sound the alarm- it’s an AMPIRS photo dump! 🚨Poster Session 1 brought the heat 🔥 Big shoutout to our amazing PRC members who rocked their posters! #NYUDental #nyuniversity #AMPIRS #Painresearchcenter

#PRC Highlight: Happy Flash back Friday! Flashing Back to Cinco De Mayo! 💃🕺🏼🪇 MPB Tea Time always celebrating in style! #PRCpride #teatime #🫖 #cincodemayo #flashbackfridays #thankyou #PRC

New research reveals prolactin as a driver of stress-induced post-surgery pain in women. Blocking prolactin shows promise for better pain management & reduced opioid use! #PostoperativePain #Prolactin #PainResearch www.pnas.org/doi/10.1073/...

Great talk given to the PRC PRIMED Club by guest speaker Manon Bohic on Spinal Oxytocin Modulates Touch Reward and Pain Relief Through Shared Dorsal Horn Circuits. Manon Bohic is a research associate at Rutgers University.👏 #Thankyou for the visit! #SpinalDorsal #PRC #womeninscience

💡 A promising non-opioid strategy—SBI-810 reduces pain, opioid reward, withdrawal, and constipation through selective β-arrestin-2 signaling www.sciencedirect.com/science/arti...

A big shoutout to Nikhil Sharma for joining our MPB Seminar Series! 🙌 @nyupainresearch.bsky.social loved your fascinating deep dive into the enteric nervous system and its connection with peripheral sensory & autonomic ganglia. 👨‍🔬🧠✨ #Neuroscience #PainResearch #MPBSeminar

Special thanks from the #painresearchcenter to @shuibingchen.bsky.social for sharing a talk on Human Pluripotent stem cells, disease modeling and drug screening. Amazing job hosting #DrEdwinRosadoOlivieri! #ChenShuibing #HumanPluripotent #PRC #thankyou!

New study reveals alarmingly high rates of illicit opioid and fentanyl use in the US, much higher than prior estimates, underscores the urgent need for better data to fight the opioid crisis. #OpioidCrisis #Fentanyl #PublicHealth jamanetwork.com/journals/jam...

PRC Highlight: Welcome to the PRC-Structural Biologist Dr. Halil Aydin and Dr. Nestor Jimenez-our Director of the PRC e-phys core!! We are so excited to have you join the team! 👏🥳🎉

Incredibly excited to work with our new neighbors in the Hi bell lab!!

Fantastic science and even more fantastic colleagues @amergastroassn.bsky.social this week. Excited and honored to be elected vice chair of the neurogastro council and work with @brad kuo and Council members! @nyupainresearch.bsky.social @newyorkuniversity.bsky.social @nyulangonepccsm.bsky.social

🎉 Congrats to @sarahanajjar.bsky.social on her awesome Data Blitz presentation and poster, “Sex Differences in Gut Serotonergic Signaling of Visceral Pain” at the USASP meeting in Chicago! 🧠💥🌟 @karapedsgastrodoc.bsky.social @nyupainresearch.bsky.social @usasp.bsky.social

Wonderful talk on immuno-modulatory materials from Jeff Hubbell, NYU’s new Vice President of Life Sciences and Engineering. We are excited to welcome the Hubbell Lab as our new neighbors!🧠💥🌟 @nyupainresearch.bsky.social @nyutandon.bsky.social @karapedsgastrodoc.bsky.social

What lawmakers decide on Capitol Hill impacts you at home & in your lab or clinic. Come to AGA Central during #DDW2025 for tips & resources from AGA advocates like @shaziamsiddique.bsky.social and @jessicakormanmd.bsky.social on how to fight for you & your patients! 📅 Monday, May 5, 12 p.m.

Amazing times with @nyupainresearch.bsky.social at the @usasp.bsky.social meeting. Congratulations to all our post docs including @pazduran.bsky.social @sarahanajjar.bsky.social for their amazing presentations! @nyupainresearch.bsky.social @newyorkuniversity.bsky.social

Acute pharmacological inhibition of PIKfyve blocks Nav1.7/1.8 sodium channels, reducing neuropathic & inflammatory pain in mice. This suggests PIKfyve as a target for novel pain therapies #painresearch #ionchannels #drugdiscovery buff.ly/iZ3aFEj

New meta-analysis shows that about 40% of adults with chronic pain also have significant depression or anxiety, highlighting the need to understand the links between mental health conditions and pain! #painresearch #chronicpain #mentalhealth

PRC Highlight: The Jensen Lab is making strides in understanding diseases at the molecular level — paving the way for #future breakthroughs in #oral health and beyond #NYUDentistry #nyuniversity #Jensenlab #3minutemondays

New study shows that MRGPRX2-mediated mast cell activation is heightened in patients with IBS, linking this pathway to increased abdominal pain and sensory hypersensitivity #IBS #AbdominalPain #GutPain

PRC Highlight: @nyupainresearch.bsky.social Dr. Steve Davidson was featured in The New York Times- offering his insights on a BMJ review that examined studies on non-surgical, interventional treatments for low back pain nytimes.com/2025/03/18/w... #nyuniversity #NYUDental #NinaAgrawal @nytimes.com

CONGRATULATIONS to Drs. Sarah Najjar, Lin Hung and Kara Margolis- Their review article: Serotonergic Control of Gastrointestinal Development, Motility, and Inflammation is one of the top 10 most cited articles published in 2023! onlinelibrary.wiley.com/doi/abs/10.100… 🥳🔝🔟

@afshin419.bsky.social @yaldamoayedi.bsky.social

Thank you to Dr. Lynn Petukhova featuring Suzanne Moloney aka CEO, #HidraWear for giving an inspiring Seminar Series hosted by Dr. Yalda Moayedi and the Department of Molecular Pathobiology @nyupainresearch.bsky.social enjoyed this #collabo @petukhova.bsky.social #SuzanneMoloney #nyuniversity #PRC

GPCR Selectivity Unlocked: A Gαi-biased agonist (LM189) shows how β2AR switches between Gαs & Gαi 🎯🔬 #BiasedSignaling #StructuralBiology #GPCR #Gproteinisoforms #LM189 www.science.org/doi/10.1126/...

🚨📸 Behold an uncurated masterpiece aka the latest #Photo #Dump 🤳🎉 shoutout to all the Collegiality Award Winners!!! 👏👏🏆#photodump #awardwinners #livingthedream #nyuniversity #NYUDental #thegemsaloon #PRC #MPB

#itchdoctor Exciting study from the Kim Lab on how mast cells and sensory neurons drive cross-organ pain 💥🧠 #VisceralPain #NeuroImmune #IBS #ICBPS www.researchsquare.com/article/rs-6...

HAPPY BIRTHDAY to all who have a birthday in March! Thank you to #MPB for hosting Tea Time ☕️🫖⏰ #turnupthursdays #happybirthday

NaV1.8/NaV1.9 double knockout mice show their combined role in pain signaling & altered gene expression in DRG neurons. Valuable for studying human pain mutations #ionchannels #pain #neuroscience

A novel mechanism behind episodic neuropathic pain—the interaction between dynamic blood vessel movements and Piezo2 mechanoreceptors in sensory neurons #piezo2 #neuropathicpain #nociceptors buff.ly/e5os312 @tbertalab.bsky.social

TRPV4 on Schwann cells is a potential mediator of mechanically induced pain in oral cancer, check out this article! #TRPV4 #oralcancerpain #Schwanncells pubmed.ncbi.nlm.nih.gov/40144515/

NYU PRC members spotted at the NYU School of Dentistry Dean's Spring Social @ Dave & Buster's! It was a great night of sushi, games, and lots of fun!