Since AI slop is again all over Scientific Reports, a thread on the economics of grey-zone publishing. Why does slop keep getting published? What does it mean for science? How can we stop this? Background readings: Understand the strain: tinyurl.com/2b6wxx5r Stop the drain: tinyurl.com/3jfscscy

Socialism is what they called public power. Socialism is what they called social security. Socialism is what they called the growth of free and independent labor organizations. Socialism is their name for almost anything that helps all the people. —Harry Truman, 1952

This team are searching for new "Asgard archaea" to sequence. Let's talk about why these bacteria-like organisms are so fascinating, why they're named for Norse mythology, and why looking at them is unlocking a better understanding of our own genomes. Once considered a type of oddball bacteria🦠...

So, I have read articles written by people who claim that the entire concept of modern medicine is bad, because "artificially" saving people's lives has put a stop to human evolution by letting genetically inferior people breed. Great that those folks are in charge of the CDC now.

Congratulations Margarida Barroso @barroso8.bsky.social for receiving the Carpenter Ranch Award from @histochemicalsoc.bsky.social ! So well deserved!

I wanted to share probably the most important sermon I’ve given and it’s while I’m being arrested. It’s torture pure and simple what happens at #Broadview. I’m ok, though I was thrown to the ground and choked with my pectoral cross. A review of the video shows I was peaceful - did I deserve this?

Research in primate brains has been essential for the development of brain-computer interfaces and artificial neural networks. New funding and policy changes put future such advances at risk, write Cory Miller, @movshon.bsky.social and Doris Tsao. #neuroskyence bit.ly/47MXYLH

Chuck Schumer Helps Pull Democrats Back From Brink Of Courage

Dems. Snatching defeat from the jaws of victory

Previously shared: Systemic shock can lead to vascular dysfunction and organ failure. This issue’s cover features work by Alejandro P. Adam @aleadam.bsky.social showing inflammatory cytokines drives endothelial stress via cytoplasmic DNA. www.jci.org/articles/vie...

Vinculin is a simple adapter protein right? Wrong! That’s been the prevailing view for the 46 years since it was discovered. Here we provide a new paradigm and show that vinculin is a complex mechanosensor itself, containing 6 binary switch domains. www.science.org/doi/10.1126/...

Here's a quick thread with pics summarizing the paper. Many thanks for all the hard work at Albany Med and by our collaborator Pilar Alcaide!

Very proud of this work that is now out on JCI describing a new #signaling pathway downstream of the #cytokine IL-6 in the #endothelium with implications in #sepsis and #shock. Short thread with a summary coming later today. For now just enjoy that gorgeous image taken by my student Fatma Awadalla!

New work from Daoud et al. shows that removal of YAP/TAZ from vascular smooth muscle cells triggers inflammation and immune activation- indicating these factors as essential in vascular health.#vascularbiology sciencedirect.com/science/arti... #CardioSky

The BICAR-ICU-2 trial just dropped! RCT involving IV bicarb in metabolic acidosis among patients with mod-severe AKI Bicarb didn't affect mortality but it reduced the need for dialysis & risk of bacteremia VERY similar conclusions to BICAR-ICU-1 🧵 #1/ jamanetwork.com/journals/jam... #EMIMCC

Stem cell research is opening new doors for treating age-related #MacularDegeneration (AMD), a leading cause of vision loss. Join our co-founders, Drs. Jeffrey Stern and Sally Temple on @BrightFocus Foundation's Macular Chat on Wed, Oct 29.

Monty Python understood p-hacking

Today, I’m joining millions of Americans participating in No Kings rallies across the nation to reject Trump’s corruption and cruelty – and to stand up for democracy. Read more in my latest newsletter, and visit nokings.org to find a rally near you: tonko.house.gov/news/email/s...

New this month in JHC: "Expression of Glial Cell Line–derived Neurotrophic Factor and Its Receptors in Glioblastoma." Click to read: bit.ly/3L1NIHz #glioblastoma #immunohistochemistry #insituhybridization

Add your name ✍ at www.nycures.org so Albany sees 10,000 scientists calling for the future of biomedical research to be built right here in New York. Our first email to members goes out soon—introducing the statewide biomedical institute we’re proposing and how you can help power it forward.

Impressive demonstration of how a leukocyte separates the two ECs to squeeze by. Time to update my TEM lecture slides!

Staff members at the NIH seem to have done the impossible: spend the agency's $48 billion budget. “Everyone has been rallying together to clean up the mess, but it’s a mess that did not need to be made,” an NIH program officer told me. www.nature.com/articles/d41...

@gabbyfredman.bsky.social EPA+DHA may be considered as part of the management of patients with NYHA functional class II-IV HF, irrespective of etiology or LVEF.

New vascular seminars coming up @evborg.bsky.social

Trump Administration Attempts To Link Autism To Tylenol https://theonion.com/trump-administration-attempts-to-link-autism-to-tylenol/

David Baltimore passed away this weekend. A pioneer of molecular virology who won the Nobel prize in medicine & physiology for his discovery of viral reverse transcriptase. This essay he wrote in 2018 reflecting of his 60yr career in science is a great read. www.annualreviews.org/content/jour...

Just signed it! www.standupforscience.net/rfk-impeachm...

Double the discovery, double the momentum 🚀 Europe doubles down on research competitiveness with a major boost to #HorizonEurope: €95.5 billion foreseen for 2021-2027 💰💰💰💰💰💰💰💰💰 €175 billion proposed for 2028-2034 💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰💰

open.substack.com/pub/clauswil... this is very true and highly under appreciated. Not just for a PhD but any high level accomplishment.

The Journal of Histochemistry and Cytochemistry, the Histochemical Society’s flagship journal for 70 years, is seeking manuscript submissions! To learn more & submit: journals.sagepub.com/author-instr... #callforpapers #histochemistry #immunohistochemistry #microscopy

ICYMI: Vasculopathy occurs early in systemic sclerosis, but intervention strategies are lacking. Colin Jamora & team reveal ANGPTL2 as an inducer of vasculopathy that drives cutaneous fibrogenesis in mice—mirroring SSc—and present a therapeutic approach: UAS03. buff.ly/xNYvnRj

Now the scientific method has about a 4% success rate 🧪🧅

🚨URGENT UPDATE ON ACLU/APHA vs NIH CASE 🚨 Court accepting updated list of plaintiffs/grantees impacted! MUST BE SUBMITTED BY **AUGUST 1st 5pm EST**! Please disseminate!!! Message from ACLU team below: 1/

Corrupt. Dangerous. Deeply deeply damaging.

Impressive work following over two thousand volunteers for over two years. Both intervention arms (structured and self guided) showed improvements. Thank you ‪@alzassociation.bsky.social‬ for your work.

Post Sunday morning shows Bhattacharya email...

The Wadsworth Center is expanding it's research focus on #virology /vector-borne diseases! www.asmcareerconnections.org/job/research-scientist-5-g-31/78488664/ This is a unicorn assistant prof equivalent position with 12-month hard money salary and no teaching commitments (!) Reposts appreciated 🙏

Some sweet people have been sending physical cards and letters to the Bethesda Declaration signers. This is so kind and meaningful. It would be GREAT if they received more. Cards can be sent to Ian Morgan NIGMS 45 Center Dr, MSC 6200 Bethesda, MD 20892-6200 Ian will share them with the signers.

It is a strange time when I think that a new policy from this administration makes sense and I actually support. I miss the times where most notices made sense, though. grants.nih.gov/grants/guide...

As Jay said, many of the #BethesdaDeclaration signers will meet with him on Monday. And oh boy are we prepared! While not every signer was invited, we worked together and with our colleagues across #NIH to bring our concerns—and evidence to back them up. Buckle up, this will be a long thread. 🧵

There is a rally on MONDAY at 4:30 PM to stand up for NIH. Please join. Many NIH employees signed the Bethesda Declaration, objecting to the destruction of NIH. The Trump NIH Director asked the signers to meet. The rally follows that meeting, in support. actionnetwork.org/ev...

Rest in peace, Ivar Ivar Giaever, Nobel Winner in Quantum Physics, Dies at 96 www.nytimes.com/2025/07/08/s...

RPI, Albany Medical College share heavy tech amid federal funding worries www.timesunion.com/education/ar...

“On Not Betraying Our Trainees, Especially Now” I won an Extraordinary Achievement Award from the Critical Care Assembly last month The @atscommunity.bsky.social premier journal @atsblueeditor.bsky.social TODAY published the remarks I made on that occasion www.atsjournals.org/doi/10.1164/...

Great new tool for multicolor superresolution live imagining

Would be honored to see @alsobrooks.senate.gov on the growing list of signers! Still appreciating the platform she provided for us at the #SickOfIt rally. Then, I wore a veil to hide my identity. Good to be unmasked!

Today, my NIH colleagues and I did something scary but really important. We spoke up about egregious harms we are seeing happen to research participants and public health through thoughtless and politicized policies at NIH. 🧵1/3 apnews.com/article/nih-...

My Canadian university, Queen's, is offering TWENTY 4-year funded PhDs (40k CAD/yr) for a student of ANY citizenship who has been accepted at a top 100 US university but have had offer rescinded OR are reconsidering offer due to US policy. Details found here👇 www.queensu.ca/grad-postdoc...

Here is the official posting for a faculty job in Pharmacology and Therapeutics at Roswell Park Comprehensive Cancer Center! Feel free to DM or email with questions. roswellpark.wd5.myworkdayjobs.com/en-US/Ext-RP...

History repeats itself, sadly. I was an undergrad student doing my first bench work in Buenos Aires when the economy minister (Cavallo) wanted to close CONICET. That was about 25 years ago... www.nature.com/articles/d41...