Early results from our Luxa Biotech-sponsored and #NEIfunded #ClinicalTrial are out in #CellStemCell. The trial uses an adult RPE stem cell therapy for dry age-related #MacularDegeneration. Beautiful cover art by Dr. Yangzi Isabel Tian. Full Text | zurl.co/gQ2bq @cellpress.bsky.social #NIHfunded

Have a safe and happy Halloween!

Stem cell research is opening new doors for treating age-related #MacularDegeneration (AMD), a leading cause of vision loss. Join our co-founders, Drs. Jeffrey Stern and Sally Temple on @BrightFocus Foundation's Macular Chat on Wed, Oct 29.

Less than two weeks left to register for the inaugural conference on Assembloids & Complex Cell-Cell Interactions at @cshlnews.bsky.social Check out the topics and amazing lineup of speakers!

A great piece by our friends at Michigan Medicine! We are grateful to have our first clinical trial in the skilled hands of Drs. Rajesh Rao of Kellogg Eye Center, David Liao of LA Retina and Theodore Leng of Stanford Medicine. Article | zurl.co/0eUMo

Science fun on this beautiful Friday in Albany! The Capital District Postdoc Association held their annual symposium at the University at Albany. NSCI was well represented by CDPA president Sol Toruella, presenters Runia Roy & Catherine Hamann, and new postdocs Jenica Acheta & Alexis Guevara!

Big news! Early results from Cohort 1 of our Luxa Biotechnology-sponsored and #NEIfunded clinical trial are now available online at Cell Stem Cell! Open Access Full Text | zurl.co/piAT4 #NIHfunded #MacularDegeneration #ClinicalTrials

Available now at @stemcellreports.bsky.social: Our #NEIfunded study led by Farhad Farjood, Nathan Boles and Jeffrey Stern reveals the surprising heterogeneity of retinal pigment epithelium cells in the human eye using single cell transcriptomics and proteomics.

🔊 Are you a detail-oriented PhD scientist with cell biology or #biomanufacturing experience? Interested in development of a novel clinical stage cell replacement therapy for dry age-related #MacularDegeneration (AMD)? We are #hiring! Learn more: zurl.co/uwrDd

Today, Liz Fisher presents "PLD3 contributions to vascular dysfunction in the context of AD" during the poster session at #AAIC2025! Poster | #107171 Time | 7:30AM – 4:15PM Where | Exhibit Hall

Today at #AAIC2025: Taylor Bertucci presents "APOE4 alters vascular cells in cognitively normal brains and in vitro models revealing early pathogenic AD contributions of endothelial cells." Session | Dissecting molecular disease mechanisms Time | 2:00 – 3:30PM Location | Hall G

Coming up at #AAIC2025, Taylor Bertucci and Liz Fisher will present data related to APOE and PLD3 contributions to vascular dysfunction in #Alzheimers Disease. Check it out! Alzheimer's Association | zurl.co/jgQ7m

📣 Just announced! Susan Sharfstein of @sunypolytechnic.bsky.social led a successful #FutureManufacturing grant application to develop next generation devices enabling advanced real-time measurement and manipulation in cellular systems. #NSFfunded

We had a terrific time with the #NIIMBLeXperience students hosted by ACPHS and the Stack Family Center for Biopharmaceutical Education and Training (CBET) program! These students are the future of pharmacy, biomanufacturing, bioengineering, and cell science. We love to see it!

Proceedings from the 2024 Global Tau Conference are available through the @alzassociation.bsky.social in collaboration with @CurePSP and the #RainwaterCharitableTrust. Full text | zurl.co/0AnwI

@reppaultonko.bsky.social, we were delighted to discuss our work with you today! We deeply appreciate your advocacy in support of our shared goal - to improve healthcare for patients and ultimately develop cures for Alzheimer's Disease, Macular Degeneration and other neurodegenerative conditions.

We were thrilled to host Dr. Kristen Brennand of @Yale University this week! She gave a terrific talk on "Using Stem Cells to Explore the Genetics Underlying Brain Disease." #Schizophrenia #StemCell @kristenbrennand.bsky.social

Congrats to the winners and to everyone who completed the @CDPHP #WorkforceTeamChallenge! @timesunion.com coverage | zurl.co/DDAjZ

Lamson broke away from runner-up Jack Huber of Delmar around the two-mile mark and never looked back in finishing in 17:06. On the women’s side, Karen Bertasso-Hughes of Selkirk added to her storied resume, claiming her sixth career Workforce Challenge title with a time of 20:05.

We had a blast at the CDPHP #WorkForceChallenge! Jack Huber took 2nd place overall for the 2nd year in a row and the whole team enjoyed the event. @drkiehl.bsky.social @gliaandcake.bsky.social

What a week! Many thanks to the #ARVO2025 organizers for a terrific meeting! We loved spending time with great colleagues, catching up with old friends and hearing about so much inspiring #VisionResearch 👀 in beautiful #SaltLakeCity. @arvoinfo.bsky.social

That's a wrap! Sally Temple, Taylor Bertucci and Kate Tubbesing all spoke at the annual #NIHfunded Alzheimer's Disease Sequencing Project #FunctionalGenomics meeting at the @gladstoneinst.bsky.social. #ADSP #FunGen #Alzheimers

Today! Jeff Stern presents "Safety & Tolerability of RPE Stem Cell-derived RPE Implantation in Patients with Dry Age-related #MacularDegeneration: Early Low Dose Clinical Outcomes" Session Title | Clinical advances in cell & gene therapy Time | 8:30 - 10:15AM Room | Ballroom B #ARVO2025

Today @ #ARVO2025: Brigitte Arduini will present "Preclinical safety and efficacy of an adult progenitor cell product, RPESC-RPE-4W, as therapy for dry Age-Related #MacularDegeneration" Session Info Title | Stem cell and gene therapy Time | 3:15 - 5pm (talk @ 3:15pm) Room | 255E

In 1 week, our own Dylan Murphy will be a guest presenter for the Opalka Gallery PechaKucha night! PechaKucha is a style of presenting in which each person has 20 slides, with 20 seconds to go over each slide, typically using only images. Dylan will present on Charles Darwin's Voyage on the Beagle!

We're looking forward to #ARVO2025! Brigitte Arduini will give a talk describing preclinical safety and efficacy studies that enabled an IND for our adult #stemcell therapy to treat dry Age-related #MacularDegeneration. Jeff Stern will present early Phase 1/2a clinical data.

😍 SOX2-positive, NESTIN-positive neural progenitor cells differentiated from patient-derived induced pluripotent stem cells. NPCs are generated, banked and quality-tested in our core facilitiy, #Neuracell, for distribution to the neuroscience research community. Neuracell | zurl.co/nmGsh

🔊 Today! Sally Temple is presenting on "Using Patient-derived Induced Pluripotent Stem Cell (iPSC)-derived Organoids to Study the Time-Course of Neurodegenerative Disease" at @Indiana University Bloomington. #organoid #neurodegeneration #Neuracell

Drs. Brigitte Arduini and Jeffrey Stern will be presenting preclinical and clinical data, respectively, on our Luxa-sponsored adult stem cell-derived investigational therapy for age-related #MacularDegeneration at the upcoming #ARVO2025 annual meeting! #ClinicalTrial Announcement | zurl.co/jHaZd

@Hudson Valley Community College hosted another terrific Capital Region STEM Poster Showcase today! Mehulkumar Pandya presented data from his NSCI internship studying Tau accumulation in patient-derived neural cells in David Butler's lab. Great job, Mehul! Event Info | zurl.co/VcWv8

Congratulations to Allison Allen, who will begin medical school at Lake Erie College of Osteopathic Medicine this fall! Alli was an intern at NSCI, first in 2019 with Jenny Wang and Xiuli Zhao.

🔊 Just out! Drs. David Butler and Eain Murphy teamed up to investigate the impact of HSV-1 infection on Tau protein pathology, a key aspect of Alzheimer's Disease and other neurodegenerative conditions. #Neuracell Open Access | zurl.co/M50DS

We are truly inspired by the PSP community and grateful for their support of our work to develop a gene therapy for PSP and other tauopathies. The 22nd annual SW Florida Support Group Awareness and Memorial Walk is this weekend in Marco Island, FL. @Curepsp | zurl.co/PO361

Congratulations to Dr. Kristen Zuloaga on her newest publication and recent promotion to full professor at Albany Medical College! We're so happy for you! @zuloagalab.bsky.social Full text | zurl.co/H0jXb

The 22nd Annual @CurePSP Awareness and Memorial Walk will be held on Saturday, March 29. This incredible community is doing important work to support patients, caregivers and researchers seeking to development treatments. Read on: Naples Daily News | zurl.co/fjYE2

We are excited for the release of early clinical data on adult retinal pigment epithelium stem cell (RPESC)-derived cell replacement therapy to treat dry Age-related Macular Degeneration! The trial is sponsored by Luxa Biotechnology with support from NEI and CIRM. Endpoints News| zurl.co/Mjhxe

CIRM blog | zurl.co/W4Ef2

Today, Sally Temple is giving the keynote for @fda.gov 's "Cell Therapies and Tissue-Based Products: A Public Workshop on Generating Scientific Evidence to Facilitate Development." We're looking forward to a terrific lineup of speakers on this important, timely topic. Info | zurl.co/G7EE8

Luxa Biotechnology, a joint venture of NSCI and Y2 Solutions, has announced that the RPESC-RPE-4W investigational adult stem cell therapy for dry Age-related #MacularDegeneration has received an RMAT designation from the U.S. FDA! Businesswire | zurl.co/eJl5o

We ❤️ directed differentiations! This year, we're looking forward to a cross-institute collaborative effort to build better neurovascular models to study Alzheimer's Disease. #stemcell #Alzheimers #neurodegeneration

Dr. Taylor Bertucci is speaking at her alma mater, Rensselaer Polytechnic Institute, today at noon! #stemcell #Alzheimers #neurodegeneration #neurovascular

ANOTHER exceptional 3D organoid models session at #SCMND2025? What a treat! Come join us in Edinburgh this March for some incredible science! Submit your abstract and register here 👉👉https://scmnd.com/ #iPSC #organoids #neuroscience #dementia #neurodegeneration #Edinburgh #UKDRI

Emerging data point to a connection between phospho-Tau, which contributes to neurodegenerative pathology, and viral infections. Several groups are studying this phenomenon from different angles, described in a recent article on Alzforum. Alzforum | zurl.co/9ZnCW

Next week, Sally Temple will be speaking at Rensselaer Polytechnic Institute on "Neurodegenerative Disease Modeling with Brain Organoids.” Where | Isermann Auditorium When | Jan 15, 3pm - 4pm #Neuracell #organoid #Alzheimers

Our hearts go out to the families, patients and caregivers affected by FTD and other neurodegenerative tauopathies. We are proud to collaborate with terrific scientists to improve understanding and advance therapies as part of the #TauConsortium. This is why we do what we do. NYT | zurl.co/hDdSP

Join today's 7:30pm poster session at the #cshlbrain meeting! Liz Fisher will present her poster "Cell type specific effects of Phospholipase D3 (PLD3) on vascular signaling networks in the context of disease." @gliaandcake.bsky.social @cshlnews.bsky.social

Check out this timely preprint in Nature on methodological and analytical rigor in the area of neural #organoids, transplantation and modeling of human brain cell types, evolution and disease. Full-text | zurl.co/jhdYA @natureportfolio.bsky.social #cshlbrain #neurodegeneration

We're looking forward to the #cshlbrain meeting next week! Drs. Sally Temple and Liz Fisher will be presenting on neurovascular aspects of #Alzheimers Disease. #organoid #neurodegeneration @cshlnews.bsky.social @gliaandcake.bsky.social zurl.co/ir9I

Congratulations to Jack Huber on winning the 2024 Turkey Trot 10K with a time of 31:06! www.timesunion.com/sports/artic...

A tremendous multi-institutional effort has combined 36 scRNA-seq datasets into a human neural #organoid cell atlas. >1.7M individual cells, comparison to human brain data, and a user interface. Check it out! Open Access | zurl.co/8Pyg