Hi @madamescientist.bsky.social Enjoy some nice music from my youngest! We need a nice music break! youtu.be/Qd46Pf_lp-4?...

📼 Mudam-se Os Tempos Mudam-se as Vontades, José Mário Branco, 1971 https://www.youtube.... #25a74

1/2 Oficiais revoltosos ocupam o QG da Região Militar, levando Santos Júnior, Comandante da PSP do Porto, a alertar o Comando da GNR. Ordens de prevenção rigorosa são emitidas, e tentativas de cooperação entre GNR, PSP e o Regimento de Cavalaria 6 são feitas para retomar o controlo do quartel.…

Comunicação de Tigre (RC Porto). O 1º comunicado só às 04h30 #25a74

📼 Portugal antes do 25 de Abril de 1974 https://bit.ly/2pYaa6r #25a74

♬ O Patrão E Nós, Fausto, 1974 https://j.mp/1jO39fO #25a74

♬ O Povo Unido Jamais Será Vencido, Luís Cília e os Quilapayún, 1974 https://www.youtube.... #25a74

♬ El Pueblo Unido Jamás Será Vencido, Sergio Ortega Alvarado e os Quilapayún, 1973 https://www.youtube.... #25a74

♬ Queixa das almas jovens censuradas, José Mário Branco, 1971 https://www.youtube.... #25a74

♬ Trova Do Vento Que Passa, Adriano Correia de Oliveira, 1964 https://www.youtube.... #25a74

Go Princeton Go! www.dailyprincetonian.com/article/2025... #princeton

he is still talking...

What it's like inside the NIH under current conditions: not good. Terrible uncertainty and low morale, and an inability to order even basic materials because of trouble with the purchasing department:

Times Union published my article today: "Science on the chopping block"

I hope to see you all at the NY State Capitol this Friday at 12:30! standupforscience2025.org/local-event-...

This update means that virtually all NIH study sections and councils, necessary to review and award grants, will not be scheduled until mid-April AT EARLIEST. The end of the fiscal year is September 30, and all appropriated monies must be spent by then. Meanwhile, the backlog continues to grow.

Read every word of this article to see what the Trump folks are doing to the good civil servants at NIH -- and to the important work that protects all of our health. www.theatlantic.com/health/archi...

wow, just wow....

I wrote an opinion piece for my hometown newspaper in Central NY about attacks on NIH/NSF/research and why this harms not just US science but local jobs and economies. Thanks @sciencehomecoming.bsky.social for sparking these efforts! I encourage others to join in! www.syracuse.com/opinion/2025...

Despite reports to the contrary there is still no movement on the #NIH federal register. No cursory notices = no study sections or councils can meet = no new or renewed funding. www.federalregister.gov/agencies/nat...

The only NIH or NSF Notice to be submitted to the federal register today was a cancelation of an NSF Advisory Panel. Federal Granting Agencies are still being kneecapped by the administration

womens college bball is the only good thing going in 2025!

Excellent talk at today's #VirtualPub by Chiara Stringiari, France BioImaging, exploring the technical possibilities & limitations of #FLIM and providing a fantastic overview of recent applications. Want to try it out? Available in #openaccess via France BioImaging & other EuroBioImaging Nodes!

Here are some data documenting the funding "pause" pulled from NIH Reporter. Current results (FY25) (Red) are compared with results from FY21 (first year of Biden Administration) and FY24. Note that data from Reporter lag behind release of NoAs by ~1 week. I will be tracking this going forward.

I just wrote to both MI senators and my representative about this issue and SO SHOULD YOU

If the block on the Federal Register isn’t removed in the next few months, I fear a majority of labs will close within a year. This small procedural wrench has the power to kill US science indefinitely, losing an entire generation of discovery and innovation.

Glad to see this post getting some traction, because the Federal Register is the WHOLE ballgame, folks. To drive this point home, a recent EO declares that all posts to FR now must be approved by the White House. www.whitehouse.gov/presidential...

This is a red alert for US science, for new cures & treatments for diseases that afflict everyone in this country. This isn't "oh, it will blow over." Soon we will have reached the point of no return destroying what it has taken decades to build. WE NEED TO BE BANGING DOWN THE DOORS IN CONGRESS.

"A freeze on meetings of expert panels that peer review grant proposals at the NIH is kicking in this week ... Trump barred NIH from posting new Federal Register notices, which means any study section not advertised before then cannot take place." #medsky 🧪 www.science.org/content/arti...

I’ve now heard the number: 41/47 study sections will not be meeting. Another end around to being forced to unfreeze the funds

SRO says they are instructed to prepare for the meetings and decisions will be made closer to the date 😵‍💫

Just received an email from a rep of a big company cancelling support to a conference I was organizing over the NIH budget cuts - with the prospects of sales down the company is cutting investment - this is food from local restaurants that will not be ordered - hotel rooms that will not be booked

ARF1 compartments are master regulators of post-Golgi trafficking www.nature.com/articles/s41... and we are now very excited to investigate their role in sorting in polarized epithelia

There hasn’t been an NIH-related post since 1/21. Despite seeing upcoming study section & council dates in eRA commons, these will not take place if they weren’t announced. They’re starving us out until the next budget unless Universities step WAY up.

NCI Council cancelled. That means all grants in funding range from the 3d review period are not going to be paid out (including mine). They kill the best biomedical research system in the world to save 0.6% of the US budget in "waste". Cancer, diabetes, Alzheimer research, new drugs. Great job.

Temporary restraining order granted against NIH www.documentcloud.org/documents/25...

A judge blocked the funding freeze on USAid but: "The Trump administration confirmed to The Associated Press that it had taken USAID off the lease of the building, which it had occupied for decades." this is illegal and by the time the courts act, if ever, there wont be any agency left!

Trombone shorty and Jon Batiste are both Skidmore Summer Jazz Institute alum! Upstate NY represented!

My fav team right now is Tennessee! wow what a never give up attitude kind of team! Pat Summitt is smiling in heaven!

Amazing day in women's college basketball! Full and enthusiastic gyms in Indiana, Texas, Louisiana and many other places.... really amazing progress.

Great lunch of the Multiphoton microscopy conference speakers at SPIE Photonics West! @digmanlab.bsky.social and many others!

Great session today on FLIM! Thanks to Ammasi Periasami for a great session! @barroso8.bsky.social @chiarastringari.bsky.social @stimulatedraman.bsky.social Michael Börsch Laura Marcu Melissa C. Skala Ahmed A. Heikal Karsten König Alex J. Walsh Irene Georgakoudi Angelika C. Rueck Krishanu Ray Et al

Last day with TissueFax slidescanner demo from TissueGnostics! Fast and high resolution confocal imaging, 6 slides or more depending on the version. Taylor, core manager of AMC's imaging facility, got very nice images of whole-tumors. Moreover, the software allows for easy to use imaging analysis

Lovely ER staining in figure 5.

SWIR intensity (top) and NIR lifetime (bottom) imaging of HER2+ spheroids (~500um) using a lightsheet mesoscope developed by Luis Chavez (intes-lab.bme.rpi.edu/people). Look for exciting new stuff coming from the Intes-Barroso collaboration in 2025!

Thanks for the great for the Barroso-Intes-Corr labs holiday party! Its wonderful to see everyone together and enjoying themselves. Happy Holidays and Happy New Year!

Congratulations to Mohd Saqib for being awarded a Keystone grant from The Histochemical Society. Mohd's project is entitled "An Integrated Imaging-Based Approach for Measuring Tumor Immune Suppression Involving PD-1/PD-L1 Interactions and Immune Response Dynamics". Well-deserved Mohd!

Very excited to tell you about a great review on "Modeling intratumor heterogeneity in breast cancer" published in Biofabrication. This was mainly the work of Liz McDonough with David Corr, RPI BME, in collaboration with Fiona Ginty from GE research labs and yours truly. doi.org/10.1088/1758...